Skip to main content

Translational Imaging

Section edited by Ravinder Reddy and Mohammed Haris

The Translational Imaging section provides a platform for rapid dissemination of the advances in medical imaging research emphasizing clinical translation. The topics covered in this section will include methodological innovations in early diagnoses of human diseases and monitoring of therapeutic responses from all the major imaging modalities (MRI, PET, US etc.,). Articles considered for publication include studies in human subjects, pre-clinical models and ex vivo systems dealing with imaging of human pathophysiologies.

Page 1 of 2

  1. Angiogenesis inhibitors have been identified to improve the efficacy of immunotherapy in recent studies. However, the delayed therapeutic effect of immunotherapy poses challenges in treatment planning. Therefo...

    Authors: Xi Xu, Mengjie Ma, Kunlin Ye, Dong Zhang, Xinhui Chen, Jiayang Wu, Xukai Mo, Zeyu Xiao, Changzheng Shi and Liangping Luo
    Citation: Journal of Translational Medicine 2024 22:198
  2. Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. This study aimed to construct immune-related long non-coding RNAs (lncRNAs) signature and radiomics signature to probe ...

    Authors: Jixin Luan, Di Zhang, Bing Liu, Aocai Yang, Kuan Lv, Pianpian Hu, Hongwei Yu, Amir Shmuel, Chuanchen Zhang and Guolin Ma
    Citation: Journal of Translational Medicine 2024 22:107
  3. Identifying precise biomarkers of immunotherapy response for non-small cell lung carcinoma (NSCLC) before treatment is challenging. This study aimed to construct and investigate the potential performance of a ...

    Authors: Jie Peng, Dan Zou, Xudong Zhang, Honglian Ma, Lijie Han and Biao Yao
    Citation: Journal of Translational Medicine 2024 22:87
  4. Hepatocellular carcinoma (HCC) is a common liver malignancy with limited treatment options. Previous studies expressed the potential synergy of sorafenib and NK cell immunotherapy as a promising approach again...

    Authors: Guangbo Yu, Zigeng Zhang, Aydin Eresen, Qiaoming Hou, Emilie Elizabeth Garcia, Zeyang Yu, Nadine Abi-Jaoudeh, Vahid Yaghmai and Zhuoli Zhang
    Citation: Journal of Translational Medicine 2024 22:76
  5. Chest Computed tomography (CT) scans detect lung nodules and assess pulmonary fibrosis. While pulmonary fibrosis indicates increased lung cancer risk, current clinical practice characterizes nodule risk of mal...

    Authors: Yucheng Liu, Hao Yun Hsu, Tiffany Lin, Boyu Peng, Anjali Saqi, Mary M. Salvatore and Sachin Jambawalikar
    Citation: Journal of Translational Medicine 2024 22:51
  6. Immune checkpoint inhibitors (ICIs) have emerged as one of the most promising first-line therapeutics in the management of non-small cell lung cancer (NSCLC). However, only a subset of these patients responds ...

    Authors: Sevinj Yolchuyeva, Leyla Ebrahimpour, Marion Tonneau, Fabien Lamaze, Michele Orain, François Coulombe, Julie Malo, Wiam Belkaid, Bertrand Routy, Philippe Joubert and Venkata SK. Manem
    Citation: Journal of Translational Medicine 2024 22:42
  7. Magnetic resonance fingerprinting (MRF) enables fast myelin quantification via the myelin water fraction (MWF), offering a noninvasive method to assess brain development and disease. However, MRF-derived MWF l...

    Authors: Hyun Gi Kim, Dongyeob Han, Jimin Kim, Jeong-Sun Choi and Kyung-Ok Cho
    Citation: Journal of Translational Medicine 2023 21:914
  8. To develop and validate a conventional MRI-based radiomic model for predicting prognosis in patients with IDH wild-type glioblastoma (GBM) and reveal the biological underpinning of the radiomic phenotypes.

    Authors: Fangzhan Guan, Zilong Wang, Yuning Qiu, Yu Guo, Dongling Pei, Minkai Wang, Aoqi Xing, Zhongyi Liu, Bin Yu, Jingliang Cheng, Xianzhi Liu, Yuchen Ji, Dongming Yan, Jing Yan and Zhenyu Zhang
    Citation: Journal of Translational Medicine 2023 21:841
  9. The recurrence and metastasis of hepatocellular carcinoma (HCC) are mainly caused by microvascular invasion (MVI). Our study aimed to uncover the cellular atlas of MVI+ HCC and investigate the underlying immune i...

    Authors: Yi Wang, Gui-Qi Zhu, Rui Yang, Cheng Wang, Wei-Feng Qu, Tian-Hao Chu, Zheng Tang, Chun Yang, Li Yang, Chang-Wu Zhou, Geng-Yun Miao, Wei-Ren Liu, Ying-Hong Shi and Meng-Su Zeng
    Citation: Journal of Translational Medicine 2023 21:734
  10. Gastrointestinal stromal tumors (GISTs) carrying different KIT exon 11 (KIT-11) mutations exhibit varying prognoses and responses to Imatinib. Herein, we aimed to determine whether computed tomography (CT) rad...

    Authors: Qing-Wei Zhang, Ran-Ying Zhang, Zhi-Bo Yan, Yu-Xuan Zhao, Xin-Yuan Wang, Jing-Zheng Jin, Qi-Xuan Qiu, Jie-Jun Chen, Zhen-Hui Xie, Jiang Lin, Hui Cao, Yan Zhou, Hui-Min Chen and Xiao-Bo Li
    Citation: Journal of Translational Medicine 2023 21:726
  11. The advent of immunotherapy, a groundbreaking advancement in cancer treatment, has given rise to the prominence of the tumor microenvironment (TME) as a critical area of research. The clinical implications of ...

    Authors: Wendi Kang, Xiang Qiu, Yingen Luo, Jianwei Luo, Yang Liu, Junqing Xi, Xiao Li and Zhengqiang Yang
    Citation: Journal of Translational Medicine 2023 21:598
  12. With metabolic alterations of the tumor microenvironment (TME) contributing to cancer progression, metastatic spread and response to targeted therapies, non-invasive and repetitive imaging of tumor metabolism ...

    Authors: Emily Hoffmann, Daniel Schache, Carsten Höltke, Jens Soltwisch, Stephan Niland, Tobias Krähling, Klaus Bergander, Martin Grewer, Christiane Geyer, Linda Groeneweg, Johannes A. Eble, Thomas Vogl, Johannes Roth, Walter Heindel, Bastian Maus, Anne Helfen…
    Citation: Journal of Translational Medicine 2023 21:577
  13. This study investigated the correlation between the expression of DARS2 and metabolic parameters of 18F-FDG PET/CT, and explored the potential mechanisms of DARS2 affecting the proliferation and glycolysis of lun...

    Authors: Xu-Sheng Liu, Ling-Ling Yuan, Yan Gao, Xing Ming, Yao-Hua Zhang, Yu Zhang, Zi-Yue Liu, Yi Yang and Zhi-Jun Pei
    Citation: Journal of Translational Medicine 2023 21:574
  14. The ventral tegmental area (VTA) contains heterogeneous cell populations. The dopaminergic neurons in VTA play a central role in reward and cognition, while CamKIIα-positive neurons, composed mainly of glutama...

    Authors: Ning Zheng, Zhu Gui, Xiaodong Liu, Yang Wu, Huadong Wang, Aoling Cai, Jinfeng Wu, Xihai Li, Challika Kaewborisuth, Zhijian Zhang, Qitian Wang, Anne Manyande, Fuqiang Xu and Jie Wang
    Citation: Journal of Translational Medicine 2023 21:543
  15. Finding a noninvasive radiomic surrogate of tumor immune features could help identify patients more likely to respond to novel immune checkpoint inhibitors. Particularly, CD73 is an ectonucleotidase that catal...

    Authors: Ralph Saber, David Henault, Nouredin Messaoudi, Rolando Rebolledo, Emmanuel Montagnon, Geneviève Soucy, John Stagg, An Tang, Simon Turcotte and Samuel Kadoury
    Citation: Journal of Translational Medicine 2023 21:507
  16. Glioma grade 4 (GG4) tumors, including astrocytoma IDH-mutant grade 4 and the astrocytoma IDH wt are the most common and aggressive primary tumors of the central nervous system. Surgery followed by Stupp proto...

    Authors: Michele Dal Bo, Maurizio Polano, Tamara Ius, Federica Di Cintio, Alessia Mondello, Ivana Manini, Enrico Pegolo, Daniela Cesselli, Carla Di Loreto, Miran Skrap and Giuseppe Toffoli
    Citation: Journal of Translational Medicine 2023 21:450
  17. Chimeric antigen receptor (CAR) T cell therapy is an exciting cell-based cancer immunotherapy. Unfortunately, CAR-T cell therapy is associated with serious toxicities such as cytokine release syndrome (CRS) an...

    Authors: Pamela Leland, Dhiraj Kumar, Sridhar Nimmagadda, Steven R. Bauer, Raj K. Puri and Bharat H. Joshi
    Citation: Journal of Translational Medicine 2023 21:367

    The Correction to this article has been published in Journal of Translational Medicine 2023 21:636

  18. To explore an optimal model to predict the response of patients with axillary lymph node (ALN) positive breast cancer to neoadjuvant chemotherapy (NAC) with machine learning using clinical and ultrasound-based...

    Authors: Hao Zhang, Wen Cao, Lianjuan Liu, Zifan Meng, Ningning Sun, Yuanyuan Meng and Jie Fei
    Citation: Journal of Translational Medicine 2023 21:337
  19. Accurate differentiation of pseudoprogression (PsP) from tumor progression (TP) in glioblastomas (GBMs) is essential for appropriate clinical management and prognostication of these patients. In the present st...

    Authors: Laiz Laura de Godoy, Suyash Mohan, Sumei Wang, MacLean P. Nasrallah, Yu Sakai, Donald M. O’Rourke, Stephen Bagley, Arati Desai, Laurie A. Loevner, Harish Poptani and Sanjeev Chawla
    Citation: Journal of Translational Medicine 2023 21:287
  20. Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impaired social and communication skills, narrow interests, and repetitive behavior. It is known that the cerebellum plays a vit...

    Authors: Manoj Kumar, Chandrakanta Hiremath, Sunil Kumar Khokhar, Eshita Bansal, Kommu John Vijay Sagar, Hansashree Padmanabha, Akhila S. Girimaji, Shweta Narayan, M. Thomas Kishore, B. K. Yamini, A. R. Jac Fredo, Jitender Saini and Rose Dawn Bharath
    Citation: Journal of Translational Medicine 2023 21:246
  21. Stratification of DNA mismatch repair (MMR) status in patients with colorectal cancer (CRC) enables individual clinical treatment decision making. The present study aimed to develop and validate a deep learnin...

    Authors: Wuteng Cao, Huabin Hu, Jirui Guo, Qiyuan Qin, Yanbang Lian, Jiao Li, Qianyu Wu, Junhong Chen, Xinhua Wang and Yanhong Deng
    Citation: Journal of Translational Medicine 2023 21:214
  22. Identifying predictive non-invasive biomarkers of immunotherapy response is crucial to avoid premature treatment interruptions or ineffective prolongation. Our aim was to develop a non-invasive biomarker for p...

    Authors: Benito Farina, Ana Delia Ramos Guerra, David Bermejo-Peláez, Carmelo Palacios Miras, Andrés Alcazar Peral, Guillermo Gallardo Madueño, Jesús Corral Jaime, Anna Vilalta-Lacarra, Jaime Rubio Pérez, Arrate Muñoz-Barrutia, German R. Peces-Barba, Luis Seijo Maceiras, Ignacio Gil-Bazo, Manuel Dómine Gómez and María J. Ledesma-Carbayo
    Citation: Journal of Translational Medicine 2023 21:174
  23. 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) identifies carotid plaque inflammation and predicts stroke recurrence.

    Authors: Eduardo Garcia, Pol Camps-Renom, Núria Puig, Alejandro Fernández-Leon, Ana Aguilera-Simón, Aleyda Benitez-Amaro, Arnau Solé, David Vilades, José Luis Sanchez-Quesada, Joan Martí-Fàbregas, Elena Jiménez-Xarrié, Sonia Benitez and Vicenta Llorente-Cortés
    Citation: Journal of Translational Medicine 2023 21:131
  24. Ki-67 labeling index (LI) is an important indicator of tumor cell proliferation in glioma, which can only be obtained by postoperative biopsy at present. This study aimed to explore the correlation between Ki-...

    Authors: Ningfang Du, Weiquan Shu, Kefeng Li, Yao Deng, Xinxin Xu, Yao Ye, Feng Tang, Renling Mao, Guangwu Lin, Shihong Li and Xuhao Fang
    Citation: Journal of Translational Medicine 2023 21:119
  25. Human epidermal growth factor receptor 2 (HER2) overexpressed associated with poor prognosis in breast cancer and HER2 has been defined as a therapeutic target for breast cancer treatment. We aimed to explore ...

    Authors: Hao Cui, Yue Sun, Dantong Zhao, Xudong Zhang, Hanqing Kong, Nana Hu, Panting Wang, Xiaoxuan Zuo, Wei Fan, Yuan Yao, Baiyang Fu, Jiawei Tian, Meixin Wu, Yue Gao, Shangwei Ning and Lei Zhang
    Citation: Journal of Translational Medicine 2023 21:44
  26. Due to the temporal and spatial heterogeneity of human epidermal growth factor receptor 2 (HER2) expression in breast tumors, immunohistochemistry (IHC) cannot accurately reflect the HER2 status in real time, ...

    Authors: Jiyun Shi, Shuaifan Du, Rongxi Wang, Hannan Gao, Qi Luo, Guozhu Hou, Yidong Zhou, Zhaohui Zhu and Fan Wang
    Citation: Journal of Translational Medicine 2023 21:19
  27. To investigate the association between computed tomography (CT)-detected extramural venous invasion (EMVI)-related genes and immunotherapy resistance and immune escape in patients with gastric cancer (GC).

    Authors: Hao Yang, Xinyi Gou, Caizhen Feng, Yinli Zhang, Fan Chai, Nan Hong, Yingjiang Ye, Yi Wang, Bo Gao and Jin Cheng
    Citation: Journal of Translational Medicine 2023 21:4
  28. Positron Emission Tomography (PET) imaging with Prostate-Specific Membrane Antigen (PSMA) and Fluorodeoxyglucose (FDG) represent promising biomarkers for risk-stratification of Prostate Cancer (PCa). We verifi...

    Authors: Matteo Bauckneht, Cecilia Marini, Vanessa Cossu, Cristina Campi, Mattia Riondato, Silvia Bruno, Anna Maria Orengo, Francesca Vitale, Sonia Carta, Silvia Chiola, Sabrina Chiesa, Alberto Miceli, Francesca D’Amico, Giuseppe Fornarini, Carlo Terrone, Michele Piana…
    Citation: Journal of Translational Medicine 2023 21:3
  29. Early prediction of response to neoadjuvant chemotherapy (NACT) is important to aid personalized treatment in osteosarcoma. Diffusion-weighted Intravoxel Incoherent Motion (IVIM) MRI was used to evaluate the p...

    Authors: Esha Baidya Kayal, Sameer Bakhshi, Devasenathipathy Kandasamy, Mehar Chand Sharma, Shah Alam Khan, Venkatesan Sampath Kumar, Kedar Khare, Raju Sharma and Amit Mehndiratta
    Citation: Journal of Translational Medicine 2022 20:625
  30. This study aimed to develop a radiogenomic prognostic prediction model for colorectal cancer (CRC) by investigating the biological and clinical relevance of intratumoural heterogeneity.

    Authors: Min-Er Zhong, Xin Duan, Ma-yi-di-li Ni-jia-ti, Haoning Qi, Dongwei Xu, Du Cai, Chenghang Li, Zeping Huang, Qiqi Zhu, Feng Gao and Xiaojian Wu
    Citation: Journal of Translational Medicine 2022 20:574
  31. Tumor-infiltrating lymphocytes (TILs) have become a promising biomarker for assessing tumor immune microenvironment and predicting immunotherapy response. However, the assessment of TILs relies on invasive pat...

    Authors: Guan-Hua Su, Yi Xiao, Lin Jiang, Ren-Cheng Zheng, He Wang, Yan Chen, Ya-Jia Gu, Chao You and Zhi-Ming Shao
    Citation: Journal of Translational Medicine 2022 20:471
  32. The aim of this study was to determine the expression and function of heterogeneous nuclear ribonucleoprotein R (HNRNPR) in esophageal carcinoma (ESCA), the correlation between its expression and 18F-fluorodeoxyg...

    Authors: Xiao-Yu Liu, Yan Gao, Xue-Yan Kui, Xu-Sheng Liu, Yao-hua Zhang, Yu Zhang, Chang-Bin Ke and Zhi-Jun Pei
    Citation: Journal of Translational Medicine 2022 20:450
  33. Several new generation CDK4/6 inhibitors have been developed and approved for breast cancer therapy in combination with endocrine therapeutics. Application of these inhibitors either alone or in combination in...

    Authors: James L. Tatum, Joseph D. Kalen, Paula M. Jacobs, Lisa A. Riffle, Amy James, Lai Thang, Chelsea Sanders, Melinda G. Hollingshead, Falguni Basuli, Jianfeng Shi and James H. Doroshow
    Citation: Journal of Translational Medicine 2022 20:375
  34. Although eukaryotic initiation factor 6 (eIF6) is a novel therapeutic target, data on its importance in the development of esophageal carcinoma (ESCA) remains limited. This study evaluated the correlation betw...

    Authors: Yan Gao, Lingling Yuan, Jing Zeng, Fuyan Li, Xiaohui Li, Fan Tan, Xusheng Liu, Huabing Wan, Xueyan Kui, Xiaoyu Liu, Changbin Ke and Zhijun Pei
    Citation: Journal of Translational Medicine 2022 20:303
  35. Prostate cancer (PCa) is the second most prevalent cancer in males worldwide, yet detecting PCa and its metastases remains a major challenging task in clinical research setups. The present study aimed to chara...

    Authors: Xi Zhang, Binbin Xia, Hong Zheng, Jie Ning, Yinjie Zhu, Xiaoguang Shao, Binrui Liu, Baijun Dong and Hongchang Gao
    Citation: Journal of Translational Medicine 2022 20:275
  36. The aim of this study was to compare Dynamic Susceptibility Contrast Enhanced MRI (DSC-MRI) and PET with [18F]flurodeoxyglucose (FDG-PET) in the diagnosis of Alzheimer’s Disease (AD) and amnestic Mild Cognitiv...

    Authors: Aleksandra Wabik, Elżbieta Trypka, Joanna Bladowska, Mikołaj Statkiewicz, Marek Sąsiadek and Anna Zimny
    Citation: Journal of Translational Medicine 2022 20:259
  37. Pantothenate kinase (PANK) is the first and rate-controlling enzymatic step in the only pathway for cellular coenzyme A (CoA) biosynthesis. PANK-associated neurodegeneration (PKAN), formerly known as Hallervor...

    Authors: Yanan Li, Jeffrey Steinberg, Zane Coleman, Shubo Wang, Chitra Subramanian, Yimei Li, Zoltan Patay, Walter Akers, Charles O. Rock, Suzanne Jackowski and Puneet Bagga
    Citation: Journal of Translational Medicine 2022 20:103
  38. Chemoresistance gradually develops during treatment of epithelial ovarian cancer (EOC). Metabolic alterations, especially in vivo easily detectable metabolites in paclitaxel (PTX)-resistant EOC remain unclear.

    Authors: Jing Lu, Ying Li, Yong Ai Li, Li Wang, An Rong Zeng, Xiao Liang Ma and Jin Wei Qiang
    Citation: Journal of Translational Medicine 2022 20:92
  39. To develop and validate a survival model with clinico-biological features and 18F- FDG PET/CT radiomic features via machine learning, and for predicting the prognosis from the primary tumor of colorectal cancer.

    Authors: Lilang Lv, Bowen Xin, Yichao Hao, Ziyi Yang, Junyan Xu, Lisheng Wang, Xiuying Wang, Shaoli Song and Xiaomao Guo
    Citation: Journal of Translational Medicine 2022 20:66
  40. The study investigated the predictive value of tumor angiogenesis observed by 18F-ALF-NOTA-PRGD2 II (denoted as 18F-Alfatide II) positron emission tomography (PET)/computed tomography (CT) before concurrent chemo...

    Authors: Yuchun Wei, Xueting Qin, Xiaoli Liu, Jinsong Zheng, Xiaohui Luan, Yue Zhou, Jinming Yu and Shuanghu Yuan
    Citation: Journal of Translational Medicine 2022 20:63
  41. The prevalence of diffuse-type gastric cancer (GC), especially signet ring cell carcinoma (SRCC), has shown an upward trend in the past decades. This study aimed to develop computed tomography (CT) based radio...

    Authors: Tao Chen, Jing Wu, Chunhui Cui, Qinglie He, Xunjun Li, Weiqi Liang, Xiaoyue Liu, Tianbao Liu, Xuanhui Zhou, Xifan Zhang, Xiaotian Lei, Wei Xiong, Jiang Yu and Guoxin Li
    Citation: Journal of Translational Medicine 2022 20:38
  42. Preoperative diagnosis of pheochromocytoma (PHEO) accurately impacts preoperative preparation and surgical outcome in PHEO patients. Highly reliable model to diagnose PHEO is lacking. We aimed to develop a mag...

    Authors: Jianqiu Kong, Junjiong Zheng, Jieying Wu, Shaoxu Wu, Jinhua Cai, Xiayao Diao, Weibin Xie, Xiong Chen, Hao Yu, Lifang Huang, Hongpeng Fang, Xinxiang Fan, Haide Qin, Yong Li, Zhuo Wu, Jian Huang…
    Citation: Journal of Translational Medicine 2022 20:31
  43. With the high spatial resolution and the potential to reach deep brain structures, ultrasound-based brain stimulation techniques offer new opportunities to non-invasively treat neurological and psychiatric dis...

    Authors: Eva Matt, Lisa Kaindl, Saskia Tenk, Anicca Egger, Teodora Kolarova, Nejla Karahasanović, Ahmad Amini, Andreas Arslan, Kardelen Sariçiçek, Alexandra Weber and Roland Beisteiner
    Citation: Journal of Translational Medicine 2022 20:26
  44. This study aimed to evaluate the utility of radiomics-based machine learning analysis with multiparametric DWI and to compare the diagnostic performance of radiomics features and mean diffusion metrics in the ...

    Authors: Kun Sun, Zhicheng Jiao, Hong Zhu, Weimin Chai, Xu Yan, Caixia Fu, Jie-Zhi Cheng, Fuhua Yan and Dinggang Shen
    Citation: Journal of Translational Medicine 2021 19:443
  45. Cystic fibrosis (CF) patients present with a variety of symptoms, including mood and cognition deficits, in addition to classical respiratory, and autonomic issues. This suggests that brain injury, which can b...

    Authors: Bhaswati Roy, Marlyn S. Woo, Susana Vacas, Patricia Eshaghian, Adupa P. Rao and Rajesh Kumar
    Citation: Journal of Translational Medicine 2021 19:419
  46. Pelvic magnetic resonance imaging (MRI) and whole-body positron emission tomography-computed tomography (PET-CT) play an important role at primary diagnostic work-up and in detecting recurrent disease in endom...

    Authors: Heidi Espedal, Hege F. Berg, Tina Fonnes, Kristine E. Fasmer, Camilla Krakstad and Ingfrid S. Haldorsen
    Citation: Journal of Translational Medicine 2021 19:406
  47. Misdiagnosis of multiple sclerosis (MS) and neuromyelitis optica (NMO) may delay the treatment, resulting in poor prognosis. However, the precise identification of these two diseases is still challenging in cl...

    Authors: Jing Huang, Bowen Xin, Xiuying Wang, Zhigang Qi, Huiqing Dong, Kuncheng Li, Yun Zhou and Jie Lu
    Citation: Journal of Translational Medicine 2021 19:377
  48. Pathological complete response (pCR) is considered a surrogate endpoint for favorable survival in breast cancer patients treated with neoadjuvant chemotherapy (NAC). Predictive biomarkers of treatment response...

    Authors: Fengling Li, Yongquan Yang, Yani Wei, Ping He, Jie Chen, Zhongxi Zheng and Hong Bu
    Citation: Journal of Translational Medicine 2021 19:348
  49. Mental disorders widely contribute to the modern global disease burden, creating a significant need for improvement of treatments. Scalp stimulation methods (such as scalp acupuncture and transcranial electric...

    Authors: Jin Cao, Thalia Celeste Chai-Zhang, Yiting Huang, Maya Nicole Eshel and Jian Kong
    Citation: Journal of Translational Medicine 2021 19:343

Annual Journal Metrics

  • 2022 Citation Impact
    7.4 - 2-year Impact Factor
    6.9 - 5-year Impact Factor
    1.458 - SNIP (Source Normalized Impact per Paper)
    1.544 - SJR (SCImago Journal Rank)

    2022 Speed
    10 days submission to first editorial decision for all manuscripts (Median)
    84 days submission to accept (Median)

    2022 Usage 
    4,243,080 downloads
    32,614 Altmetric mentions