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Nutrition & Metabolism

Section edited by Laura Soldati

This section aims to provide a platform for the interaction and mutual validation between basic and applied research in the field of nutrition. In the area of Translational Medicine, we believe that the field ought to be taken into greater account in order to generate advanced applications for diagnosis and therapy and, at the same time, to develop new instruments of investigation.

Studies on all aspects of nutrition and metabolism with applications in medicine and biotechnology will be considered for publication. The section not only welcomes contributions that employ traditional clinical, metabolic and epidemiologic methods, but is also interested in molecular and cell biology applied to human and animal nutrition.

Featured articles

Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade
Hsing-Chun Kuo, et al

Obesity and colorectal cancer: molecular features of adipose tissue
Javier Martinez-Useros and Jesus Garcia-Foncillas

Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation
Tri Vuong, et al

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  1. Vitamin D deficiency is common among the population, but its relationship with mortality of postmenopausal females is unclear. The aim of this study is to explore the association between serum 25-Hydroxyvitami...

    Authors: Jia-Wei Shi, Jiang-Nan Wu, Xiao-Yong Zhu, Wen-Hui Zhou, Jin-Ying Yang and Ming-Qing Li
    Citation: Journal of Translational Medicine 2023 21:629
  2. Owing to the heterogeneity of Alzheimer's disease (AD), its pathogenic mechanisms are yet to be fully elucidated. Evidence suggests an important role of metabolism in the pathophysiology of AD. Herein, we iden...

    Authors: Piaopiao Lian, Xing Cai, Cailin Wang, Ke Liu, Xiaoman Yang, Yi Wu, Zhaoyuan Zhang, Zhuoran Ma, Xuebing Cao and Yan Xu
    Citation: Journal of Translational Medicine 2023 21:628
  3. Triglyceride glucose index (TyG index) has been recommended as an alternative indicator of insulin resistance. However, the association between TyG and regression from prediabetes to normoglycemia remains to b...

    Authors: Xiaojie Chen, Danfeng Liu, Weiting He, Haofei Hu and Wenjian Wang
    Citation: Journal of Translational Medicine 2023 21:624
  4. Chronic obstructive pulmonary disease (COPD) patients often exhibit gastrointestinal symptoms, A potential association between COPD and Colorectal Cancer (CRC) has been indicated, warranting further examination.

    Authors: Youtao Zhou, Zikai Lin, Shuojia Xie, Yuan Gao, Haobin Zhou, Fengzhen Chen, Yuewu Fu, Cuiyan Yang and Chuanfeng Ke
    Citation: Journal of Translational Medicine 2023 21:587
  5. Insulin resistance (IR) is considered the main driver of obesity related metabolic complications, and is related to oxidative stress and inflammation, which in turn promote each other. There is currently no sp...

    Authors: Álvaro González-Domínguez, Thalía Belmonte, Jesús Domínguez-Riscart, Pablo Ruiz-Ocaña, Inés Muela-Zarzuela, Ana Saez-Benito, Raúl Montañez-Martínez, Rosa M. Mateos and Alfonso M. Lechuga-Sancho
    Citation: Journal of Translational Medicine 2023 21:559
  6. Limited research has been conducted on the potential relationship between the dietary inflammation index (DII) and mortality, particularly in individuals with Helicobacter pylori (H. pylori) infection. This st...

    Authors: Yu-Jun Xiong, Lei-Lei Du, Yun-Lian Diao, Jun Wen, Xiang-Bin Meng, Jun Gao, Chun-Li Shao, Wen-Yao Wang, Xing-yun Zhu and Yi-Da Tang
    Citation: Journal of Translational Medicine 2023 21:538
  7. Studies have examined the effect of weight change on osteoporosis, but the results were controversial. Among them, few had looked at weight change over the life span. This study aimed to fill this gap and inve...

    Authors: Jiacheng Wang, Yi Zheng, Yawen Wang, Chengjun Zhang, Yanfeng Jiang, Chen Suo, Mei Cui, Tiejun Zhang, Xingdong Chen and Kelin Xu
    Citation: Journal of Translational Medicine 2023 21:536
  8. No evidence has been found of a relationship between remnant cholesterol (RC) and the likelihood of gestational diabetes mellitus (GDM) in pregnant women. The aim of our study was to investigate the link betwe...

    Authors: Yajing Gao, Yanhua Hu and Lan Xiang
    Citation: Journal of Translational Medicine 2023 21:531
  9. This paper aimed to examine the effects of probiotics on eight factors in overweight or obese children by meta-analysis, namely, body mass index (BMI), total cholesterol (TC), triglyceride (TG), high-density l...

    Authors: Ya Li, Tonghua Liu, Lingling Qin and Lili Wu
    Citation: Journal of Translational Medicine 2023 21:525
  10. Abdominal obesity has long been considered as a crucial risk factor of stroke. Chinese visceral adiposity index (CVAI), a novel surrogate indicator of abdominal obesity, has been confirmed as a better predicto...

    Authors: Zenglei Zhang, Lin Zhao, Yiting Lu, Xu Meng and Xianliang Zhou
    Citation: Journal of Translational Medicine 2023 21:518
  11. Diet may influence biological aging and the discrepancy (∆age) between a subject’s biological age (BA) and chronological age (CA). We aimed to investigate the correlation of dietary flavonoids with the ∆age of...

    Authors: Wenmin Xing, Wenyan Gao, Zhenlei Zhao, Xiaogang Xu, Hongyan Bu, Huili Su, Genxiang Mao and Jun Chen
    Citation: Journal of Translational Medicine 2023 21:492
  12. The pathogenic mechanisms shared between kidney stones and diabetes at the transcriptional level remain elusive, and the molecular mechanisms by which resveratrol exerts its protective effects against these co...

    Authors: Shanlin Shen, Jiafeng Wei, Weiting Kang and Tengteng Wang
    Citation: Journal of Translational Medicine 2023 21:491
  13. Diabetic nephropathy (DN) is one of the serious microvascular complications of diabetes mellitus (DM). A growing body of research has demonstrated that the inflammatory state plays a critical role in the incid...

    Authors: Meng Yan, Wenwen Li, Rui Wei, Shuwen Li, Yan Liu, Yuqian Huang, Yunye Zhang, Zihao Lu and Qian Lu
    Citation: Journal of Translational Medicine 2023 21:490
  14. The plant-based paleolithic diet (PD) and the paleolithic-like lifestyle (PLL) may reduce the risk of chronic diseases, including colorectal adenomas. These dietary and lifestyle approaches are proposed to exe...

    Authors: Yi Xiao, Yaxu Wang, Haitao Gu, Zhiquan Xu, Yunhao Tang, Hongmei He, Linglong Peng and Ling Xiang
    Citation: Journal of Translational Medicine 2023 21:482
  15. Obesity is a condition that is often associated with sleep disorders, including reduced sleep quality (SQ). Very low calorie ketogenic diet (VLCKD) has proven to be effective in the management of obesity and a...

    Authors: Luigi Barrea, Ludovica Verde, Cherubino Di Lorenzo, Silvia Savastano, Annamaria Colao and Giovanna Muscogiuri
    Citation: Journal of Translational Medicine 2023 21:479
  16. Diabetic retinopathy (DR) development is associated with disturbances in the gut microbiota and related metabolites. Butyric acid is one of the short-chain fatty acids (SCFAs), which has been found to possess ...

    Authors: Yinhua Huang, Zhijie Wang, Bo Ye, Jacey Hongjie MA, Shangli Ji, Wang Sheng, Suna Ye, Yiwen Ou, Yanfang Peng, Xu Yang, Jiansu Chen and Shibo Tang
    Citation: Journal of Translational Medicine 2023 21:451
  17. This systematic review and meta-analysis study aimed to evaluate the effectiveness of probiotics supplementation on glycaemic control in patients with type 2 diabetes mellitus (T2DM) based on the data from the...

    Authors: Guang Li, Hao Feng, Xin-Liang Mao, Yan-Jun Deng, Xiao-Bao Wang, Qiong Zhang, Yan Guo and Su-Mei Xiao
    Citation: Journal of Translational Medicine 2023 21:442
  18. Impaired sensitivity to thyroid hormones is a newly proposed clinical entity associated with hyperuricemia in the subclinical hypothyroid population. However, it is unknown whether the association exists in th...

    Authors: Zhiyuan Wu, Yue Jiang, Pingan Li, Yutao Wang, Haiping Zhang, Zhiwei Li, Xia Li, Lixin Tao, Bo Gao and Xiuhua Guo
    Citation: Journal of Translational Medicine 2023 21:436
  19. Sarcopenia has been recognized as a third category of complications in people with diabetes. However, few studies focus on the reduction of skeletal muscle mass in young people with diabetes. The aim of this s...

    Authors: Ruina Li, Sixian Lin, Jiayuan Tu, Yongzhuang Chen, Bin Cheng, Xiaoqiao Mo and Tian Xie
    Citation: Journal of Translational Medicine 2023 21:393
  20. Diabetic kidney disease (DKD) is a severe complication of diabetes. Currently, no effective measures are available to reduce the risk of DKD progression. This study aimed to establish a weighted risk model to ...

    Authors: Tianxiao Zhang, Xiaodan Wang, Yueying Zhang, Ying Yang, Congying Yang, Huiyi Wei and Qingbin Zhao
    Citation: Journal of Translational Medicine 2023 21:381
  21. Diabetic kidney disease (DKD) has been the leading cause of chronic kidney disease in developed countries. Evidence of the benefits of resveratrol (RES) for the treatment of DKD is accumulating. However, compr...

    Authors: Shengnan Chen, Bo Li, Lei Chen and Hongli Jiang
    Citation: Journal of Translational Medicine 2023 21:380
  22. Observational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between omega-3 fatty acids and type 2 diabetes. We aim to evaluate the causa...

    Authors: Chunyan Hu, Yulin Zhou, Xueyan Wu, Xiaojing Jia, Yuanyue Zhu, Ruizhi Zheng, Shuangyuan Wang, Lin Lin, Hongyan Qi, Hong Lin, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yu Xu, Yuhong Chen…
    Citation: Journal of Translational Medicine 2023 21:370
  23. Higher vitamin D concentrations and grip strength contribute to lower individual-level risk of dementia, while apolipoprotein 4 (APOE e4) genotype carries increases dementia risk, but whether combination of id...

    Authors: Jiangtao Feng, Qi Wang and Yuan Zhang
    Citation: Journal of Translational Medicine 2023 21:355
  24. Central precocious puberty (CPP) is a common disease in prepubertal children and results mainly from disorders in the endocrine system. Emerging evidence has highlighted the involvement of gut microbes in horm...

    Authors: Xiaoyan Huang, Jixiong Chen, Haozhe Zou, Peng Huang, Hailing Luo, Haidan Li, Yuhua Cai, Li Liu, Yongsheng Li, Xiaojie He and Wei Xiang
    Citation: Journal of Translational Medicine 2023 21:316
  25. Alcoholism is a widespread and damaging behaviour of people throughout the world. Long-term alcohol consumption has resulted in alcoholic liver disease (ALD) being the leading cause of chronic liver disease. M...

    Authors: Chuyun Yan, Wanting Hu, Jinqi Tu, Jinyao Li, Qionglin Liang and Shuxin Han
    Citation: Journal of Translational Medicine 2023 21:300
  26. Micronutrients have been associated with disease severity and poorer clinical outcomes in patients with COVID-19. However, there is a paucity of studies examining if the relationship with micronutrient status ...

    Authors: Josh McGovern, John Wadsworth, Anthony Catchpole, Conor Richards, Donald C. McMillan, Tadhg Kelliher, Emma Goodall, Ellie Murray, Terry Melaugh, Shannon McPhillips, Kathryn Brice, Katie Barbour, Sophie Robinson, Peter Moffitt, Olivia Kemp, Dinesh Talwar…
    Citation: Journal of Translational Medicine 2023 21:284
  27. There are inconsistent results of cohort studies analyzing the association between fish intake and mortality.

    Authors: Jian Zhou, Xiankui Tan, Yihan Li, Rongjun Wan, Ziyi Wu, Zhengjun Lin, Wanchun Wang, Yingquan Luo and Tang Liu
    Citation: Journal of Translational Medicine 2023 21:280
  28. Non-alcoholic fatty liver disease (NAFLD) is a serious public health issue globally, currently, the treatment of NAFLD lies still in the labyrinth. In the inchoate stage, the combinatorial application of food ...

    Authors: Ki-Kwang Oh, Sang-Jun Yoon, Su-Been Lee, Sang Youn Lee, Haripriya Gupta, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Dong Joon Kim and Ki-Tae Suk
    Citation: Journal of Translational Medicine 2023 21:263
  29. Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resista...

    Authors: Duygu Ağagündüz, Mehmet Arif Icer, Ozge Yesildemir, Tevfik Koçak, Emine Kocyigit and Raffaele Capasso
    Citation: Journal of Translational Medicine 2023 21:240
  30. The impact of integrated lifestyles on health has attracted a lot of attention. It remains unclear whether adherence to low-risk healthy lifestyle factors is protective in individuals with metabolic syndrome a...

    Authors: Mengying Niu, Jiahao Chen, Rongyao Hou, Yu Sun, Qi Xiao, Xudong Pan and Xiaoyan Zhu
    Citation: Journal of Translational Medicine 2023 21:239
  31. To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways.

    Authors: Fayaz Ahmad Mir, Raghvendra Mall, Ehsan Ullah, Ahmad Iskandarani, Farhan Cyprian, Tareq A. Samra, Meis Alkasem, Ibrahem Abdalhakam, Faisal Farooq, Shahrad Taheri and Abdul-Badi Abou-Samra
    Citation: Journal of Translational Medicine 2023 21:229
  32. Diabetic nephropathy (DN) is a main cause of chronic renal failure. Despite decades of extensive study, the molecular mechanisms underlying diabetic tubulointerstitial injury remain unclear. We aim to identify...

    Authors: Jialu Liu, Guangzhong Duan, Wenxia Yang, Shumin Zhang, Fuyou Liu, Youming Peng, Lin Sun, Yu Liu and Li Xiao
    Citation: Journal of Translational Medicine 2023 21:228
  33. The impact of metabolically healthy obesity (MHO) on kidney dysfunction remains debatable. Moreover, few studies have focused on the early stages of kidney dysfunction indicated by hyperfiltration and mildly r...

    Authors: Hong Zhang, Rui Chen, Xiaohong Xu, Minxing Yang, Wenrong Xu, Shoukui Xiang, Long Wang, Xiaohong Jiang, Fei Hua and Xiaolin Huang
    Citation: Journal of Translational Medicine 2023 21:216
  34. Increased circulating uric acid (UA) concentration may disrupt cardiac function in heart failure patients, but the specific mechanism remains unclear. Here, we postulate that hyperuremia induces sterol regulat...

    Authors: Bowen Lou, Haoyu Wu, Hannes Ott, Katrin Bennewitz, Chen Wang, Gernot Poschet, Hui Liu, Zuyi Yuan, Jens Kroll and Jianqing She
    Citation: Journal of Translational Medicine 2023 21:199
  35. Body mass index (BMI) and lipid parameters are the most commonly used anthropometric parameters and biomarkers for assessing nonalcoholic fatty liver disease (NAFLD) risk. This study aimed to assess and quanti...

    Authors: Song Lu, Qiyang Xie, Maobin Kuang, Chong Hu, Xinghui Li, Huijian Yang, Guotai Sheng, Guobo Xie and Yang Zou
    Citation: Journal of Translational Medicine 2023 21:192
  36. Despite the many signs of progress in pharmacotherapies, metabolic syndrome (MetS) is one of the main public-health burdens worldwide. Our study aimed to compare the effect of breastfeeding (BF) in women with ...

    Authors: Maryam Farahmand, Maryam Rahmati, Fereidoun Azizi and Fahimeh Ramezani Tehrani
    Citation: Journal of Translational Medicine 2023 21:177
  37. Previous studies have reported that high fasting plasma glucose (FPG), even that within the normal range, is associated with the risk of type 2 diabetes (T2D). Nevertheless, these findings are limited to speci...

    Authors: Linfeng He, Wenbin Zheng, Zeyu Li, Lu Chen, Wen Kong and Tianshu Zeng
    Citation: Journal of Translational Medicine 2023 21:175
  38. Type 2 diabetes (T2D) is a critical healthcare challenge and priority in Qatar which is listed amongst the top 10 countries in the world, with its prevalence presently at 17% double the global average. MicroRN...

    Authors: Sahar I. Da’as, Ikhlak Ahmed, Waseem H. Hasan, Doua A. Abdelrahman, Elbay Aliyev, Sabah Nisar, Ajaz Ahmad Bhat, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Khalid A. Fakhro and Ammira S. Al-Shabeeb Akil
    Citation: Journal of Translational Medicine 2023 21:171
  39. The relationship between muscle and prognosis, especially that between muscle distribution across different body parts, and the related prognosis is not well established.

    Authors: Chen-An Liu, Tong Liu, Yi-Zhong Ge, Meng-Meng Song, Guo-Tian Ruan, Shi-Qi Lin, Hai-Lun Xie, Jin-Yu Shi, Xin Zheng, Yue Chen, Liuyi Shen, Li Deng and Han-Ping Shi
    Citation: Journal of Translational Medicine 2023 21:154
  40. Studies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on a...

    Authors: Mina Amiri, Maryam Mousavi, Fereidoun Azizi and Fahimeh Ramezani Tehrani
    Citation: Journal of Translational Medicine 2023 21:137
  41. Obesity is accompanied by hormonal, inflammatory and endothelial alterations. These alterations induce a stimulation of several other mechanisms that contribute to the hypertensive state and to increase the ca...

    Authors: Luigi Barrea, Ludovica Verde, Pasquale Santangeli, Stefania Lucà, Annamaria Docimo, Silvia Savastano, Annamaria Colao and Giovanna Muscogiuri
    Citation: Journal of Translational Medicine 2023 21:128
  42. Computed tomographies (CT) are useful for identifying muscle loss in non-small lung cancer (NSCLC) cachectic patients. However, we lack consensus on the best cutoff point for pectoralis muscle loss. We aimed t...

    Authors: Sarah Santiloni Cury, Diogo de Moraes, Jakeline Santos Oliveira, Paula Paccielli Freire, Patricia Pintor dos Reis, Miguel Luiz Batista Jr, Érica Nishida Hasimoto and Robson Francisco Carvalho
    Citation: Journal of Translational Medicine 2023 21:116
  43. Endometrial cancer (EC) is a common gynecological cancer that endangers women health. Although substantial progresses of EC management have been achieved in recent years, the incidence of EC still remains high...

    Authors: Pengzhu Huang, Xiangqin Fan, Hongfei Yu, Kaiwen Zhang, Huanrong Li, Yingmei Wang and Fengxia Xue
    Citation: Journal of Translational Medicine 2023 21:94
  44. Observational studies have found that both short and long sleep duration are associated with increased risk of metabolic syndrome (MetS). This study aimed to examine the associations of genetically determined ...

    Authors: Yannis Yan Liang, Jie Chen, Miaoguan Peng, Jiajin Zhou, Xinru Chen, Xiao Tan, Ningjian Wang, Huan Ma, Lan Guo, Jihui Zhang, Yun-Kwok Wing, Qingshan Geng and Sizhi Ai
    Citation: Journal of Translational Medicine 2023 21:90
  45. Albumin is the most abundant protein in serum and serves as a transporter of free fatty acids (FFA) in blood vessels. In type 2 diabetes mellitus (T2DM) patients, the reduced serum albumin level is a risk fact...

    Authors: Hongyi Liu, Anji Ju, Xuan Dong, Zongrui Luo, Jiaze Tang, Boyuan Ma, Yan Fu and Yongzhang Luo
    Citation: Journal of Translational Medicine 2023 21:89
  46. Diabetic nephropathy (DN) is a complex disease involving the upregulation of many inflammation-related proteins. Alternative polyadenylation (APA), a crucial post-transcriptional regulatory mechanism, has been...

    Authors: Tingting Zhao, Dongdong Zhan, Shuang Qu, Song Jiang, Wenhua Gan, Weisong Qin, Chunxia Zheng, Fang Cheng, Yinghui Lu, Mingwei Liu, Jinsong Shi, Hongwei Liang, Yi Wang, Jun Qin, Ke Zen and Zhihong Liu
    Citation: Journal of Translational Medicine 2023 21:86

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  • 2022 Citation Impact
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    6.9 - 5-year Impact Factor
    1.458 - SNIP (Source Normalized Impact per Paper)
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