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Cancer Metabolism

Section edited by Violena Pietrobon

© © natali_mis / stock.adobeTumor cells reprogram nutrient acquisition and metabolic pathways to support abnormal growth and metastasis, a dysfunctional process that is a hallmark of cancer. 

The Cancer Metabolism section will offer a solid framework to promote and disseminate innovative studies examining metabolic reprogramming in cancer cells, including fatty acid, mitochondrial, glycolytic and other metabolic networks.

We are interested in research that investigates and characterizes metabolic alterations in tumors at the molecular level by explaining why this reprogramming occurs and identifying links between such phenomena and cell proliferation and metastasis. We will also consider studies regarding the correlation between genomic mutations, gene expression, epigenetic regulation and metabolic pathway alterations. Of particular interest are investigations focused on translational and clinical aspects and those regarding metabolically targeted pharmacological therapies, with emphasis on patient responsiveness.

  1. Currently, no molecular classification is established for bladder cancer based on metabolic characteristics. Therefore, we conducted a comprehensive analysis of bladder cancer metabolism-related genes using mu...

    Authors: Chaozhi Tang, Meng Yu, Jiakang Ma and Yuyan Zhu

    Citation: Journal of Translational Medicine 2021 19:205

    Content type: Research

    Published on:

  2. Liver fibrosis occurs in response to any etiology of chronic liver injury. Lack of appropriate clinical intervention will lead to liver cirrhosis or hepatocellular carcinoma (HCC), seriously affecting the qual...

    Authors: Jingyao Cai, Min Hu, Zhiyang Chen and Zeng Ling

    Citation: Journal of Translational Medicine 2021 19:186

    Content type: Review

    Published on: