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Section edited by Mary Salvatore

The Fibrosis section aims to gather current high-quality research to better understand the process of normal tissue repair as well as the pathogenetic mechanisms responsible for the onset and progression of tissue fibrosis that leads to organ dysfunction and failure. Fibrosis is the common denominator in a variety of chronic diseases including idiopathic pulmonary fibrosis, liver cirrhosis, and ulcerative colitis, among others. These fibrotic diseases affect a vast number of people across the world significantly impacting the quality of their life and increasing health care costs.

The section will focus on high-quality research from basic science to clinical trials. The expert members of our Editorial Board are committed to ensuring a productive scientific discussion and welcome your thought-provoking contributions to Fibrosis.

  1. Renal tubulointerstitial fibrosis is the hallmark of various chronic kidney diseases. Symmetric dimethylarginine (SDMA) is an independent cardiovascular risk factor in patients with chronic kidney diseases, wh...

    Authors: Yanzhe Wang, Ming Wu, Dongping Chen, Bo Tan, Pinglan Lin, Di Huang and Chaoyang Ye
    Citation: Journal of Translational Medicine 2023 21:326
  2. Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT. Howev...

    Authors: Liangmei Chen, Xiaofan Li, Yiyao Deng, Jianwen Chen, Mengjie Huang, Fengge Zhu, Zhumei Gao, Lingling Wu, Quan Hong, Zhe Feng, Guangyan Cai, Xuefeng Sun, Xueyuan Bai and Xiangmei Chen
    Citation: Journal of Translational Medicine 2023 21:323
  3. Hypertrophic scar is a fibrotic disease following wound healing and is characterized by excessive extracellular matrix deposition. Autologous microfat grafting proves an effective strategy for the treatment th...

    Authors: Qian Yu, Qiang Dai, Zonglin Huang, Chen Li, Li Yan, Xin Fu, Qian Wang, Yi Zhang, Lei Cai, Zhigang Yang and Ran Xiao
    Citation: Journal of Translational Medicine 2023 21:231
  4. Fibrosis, a process caused by excessive deposition of extracellular matrix (ECM), is a common cause and outcome of organ failure and even death. Researchers have made many efforts to understand the mechanism o...

    Authors: Yangdan Liu, Dongsheng Wen, Chiakang Ho, Li Yu, Danning Zheng, Steven O’Reilly, Ya Gao, Qingfeng Li and Yifan Zhang
    Citation: Journal of Translational Medicine 2023 21:164
  5. Authors: Monica Pernia Marin and Mary Salvatore
    Citation: Journal of Translational Medicine 2023 21:59