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Translational Metagenomics

Section edited by Souhaila Al Khodor

© Kateryna_Kon / stock.adobe.comThe Translational Metagenomics section aims to embrace studies addressing the role of the human microbiome in health and disease. This section encompasses studies about the development and application of metagenomics, metatranscriptomics, microbial metabolomics or novel bioinformatics tools used to improve our knowledge on the microbiome. 

The Translational Metagenomics section is especially interested in studies that go beyond description of the microbial composition and include experimental models used to support the proposed role of the microbiome in human health and diseases. In addition, studies about metagenomics integration with other omics are highly recommended. Studies of pathogens interaction with the host will not be considered.

  1. The causes of gestational diabetes mellitus (GDM) are still unclear. Recent studies have found that the imbalance of the gut microbiome could lead to disorders of human metabolism and immune system, resulting ...

    Authors: Yao Su, Hong-Kun Wang, Xu-Pei Gan, Li Chen, Yan-Nan Cao, De-Cui Cheng, Dong-Yao Zhang, Wen-Yu Liu, Fei-Fei Li and Xian-Ming Xu

    Citation: Journal of Translational Medicine 2021 19:366

    Content type: Research

    Published on:

  2. Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis (UC) and Crohn's Disease, are most often a polygenic disorder with contributions from the intestinal microbiome, defects in barrier funct...

    Authors: Juan Huang, Ziyan Yang, Yanyun Li, Xingxing Chai, Yanfang Liang, Bihua Lin, Ziyu Ye, Shaobing Zhang, Zhengping Che, Hailiang Zhang, Xueying Zhang, Zhao Zhang, Tao Chen, Weiqing Yang and Jincheng Zeng

    Citation: Journal of Translational Medicine 2021 19:356

    Content type: Research

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  3. The gastrointestinal microbiome is an important component of the human body and is closely related to human health and disease. This study describes the hotspots of the human gastrointestinal microbiome resear...

    Authors: Xingzhu Yuan, Chengting Chang, Xinrong Chen and Ka Li

    Citation: Journal of Translational Medicine 2021 19:327

    Content type: Review

    Published on:

  4. Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmun...

    Authors: Xiuli Lin, Yingying Liu, Lili Ma, Xiaomeng Ma, Liping Shen, Xueying Ma, Zhaoyu Chen, Hao Chen, Donghong Li, Zhumin Su and Xiaohong Chen

    Citation: Journal of Translational Medicine 2021 19:317

    Content type: Research

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  5. The fecal microbiota in pancreatic ductal adenocarcinoma (PDAC) and in autoimmune pancreatitis (AIP) patients remains largely unknown. We aimed to characterize the fecal microbiota in patients with PDAC and AI...

    Authors: Wenli Zhou, De Zhang, Zhengpeng Li, Huiqing Jiang, Jingnan Li, Rongrong Ren, Xuefeng Gao, Jianfeng Li, Xin Wang, Weifeng Wang and Yunsheng Yang

    Citation: Journal of Translational Medicine 2021 19:215

    Content type: Research

    Published on: