Skip to main content

Cell Death and Senescence

Section edited by Lorenzo Gullazzi and Melissa Myint

© © ipopba / Getty Images / iStockThis section aims to to provide a platform for research on cell death and senescence. Dysfunctions in the molecular and cellular mechanisms through which individual eukaryotic cells respond to stress (either successfully or not) and interact with their host in the process, including (but not limited to) the DNA damage response, the unfolded protein response, autophagy, RCD and cellular senescence have been attributed pathological significance in a plethora of human disorders

This section welcomes original research contributions, review articles, and commentaries discussing mechanistic and pathophysiological aspects of these processes. 

  1. The identifying of B-cell lymphoma 2 (Bcl-2) as a therapeutic target has led to a paradigm shift in acute myeloid leukemia (AML) treatment. Pyroptosis is a novel antitumor therapeutic mechanism due to its cyto...

    Authors: Fanghua Ye, Wen Zhang, Chenying Fan, Jiajia Dong, Min Peng, Wenjun Deng, Hui Zhang and Liangchun Yang
    Citation: Journal of Translational Medicine 2023 21:606