Skip to content

Advertisement

Disease biomarkers

Section edited by Xiangdong Wang

This section aims to bridge the identification and validation of discovered gene or protein-based, network or dynamic network biomarkers with human diseases, patient phenotypes, or clinical applications, and accelerate the development of human disease-specific biomarkers for the early diagnosis, monitoring, evaluation, and prediction of diseases. Conditions including cancers, cardiovascular and metabolic diseases will be the focus of study. This section will promote the innovation and development of disease-specific biomarkers by integrating multidisciplinary aspects of science.

Studies considered for publication include those regarding the development of advanced biotechnologies for biomarker discovery and development, identifying biomarkers associated with the early detection of diseases, monitoring of disease severity and duration as well as patient responses to therapies, prediction of patient outcomes and the evaluation, regulation and ethics of disease biomarkers.

Page 1 of 5

  1. Content type: Research

    MUC4 is a membrane-bound mucin that promotes carcinogenetic progression and is often proposed as a promising biomarker for various carcinomas. In this manuscript, we analyzed large scale genomic datasets in or...

    Authors: Nicolas Jonckheere and Isabelle Van Seuningen

    Citation: Journal of Translational Medicine 2018 16:259

    Published on:

  2. Content type: Research

    Even though multi-focused psychosocial residence rehabilitation intervention (MPRRI) programs are widely implemented by the Shanghai Cancer Rehabilitation Club, these programs have not been rigorously evaluate...

    Authors: Xuefen Chen, Xiaohuan Gong, Changhong Shi, Li Sun, Zheng Tang, Zhengping Yuan, Jiwei Wang and Jinming Yu

    Citation: Journal of Translational Medicine 2018 16:250

    Published on:

  3. Content type: Research

    Metabolomics represent a valuable tool to recover biological information using body fluids and may help to characterize pathophysiological mechanisms of the studied disease. This approach has not been widely u...

    Authors: Abdellah Tebani, Lenaig Abily-Donval, Isabelle Schmitz-Afonso, Bénédicte Héron, Monique Piraud, Jérôme Ausseil, Farid Zerimech, Bruno Gonzalez, Stéphane Marret, Carlos Afonso and Soumeya Bekri

    Citation: Journal of Translational Medicine 2018 16:248

    Published on:

  4. Content type: Commentary

    We have previously reported that nuclear expression of the Hippo transducer TAZ in association with Wnt pathway mutations negatively impacts survival outcomes in advanced gastric cancer (GC) patients. Here, we...

    Authors: Matteo Pallocca, Frauke Goeman, Francesca De Nicola, Elisa Melucci, Francesca Sperati, Irene Terrenato, Laura Pizzuti, Beatrice Casini, Enzo Gallo, Carla Azzurra Amoreo, Patrizia Vici, Luigi Di Lauro, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Marco Mazzotta…

    Citation: Journal of Translational Medicine 2018 16:247

    Published on:

  5. Content type: Research

    Alternative N-glycosylation has significant structural and functional consequences on immunoglobulin G (IgG) and can affect immune responses, acting as a switch between pro- and anti-inflammatory IgG functionalit...

    Authors: Di Liu, Xi Chu, Hao Wang, Jing Dong, Si-Qi Ge, Zhong-Yao Zhao, Hong-Li Peng, Ming Sun, Li-Juan Wu, Man-Shu Song, Xiu-Hua Guo, Qun Meng, You-Xin Wang, Gordan Lauc and Wei Wang

    Citation: Journal of Translational Medicine 2018 16:235

    Published on:

  6. Content type: Research

    Expression of the NPM1 gene, encoding nucleophosmin, is upregulated in cancers. Although more than ten NPM1 transcripts are known, the reports were usually limited to one predominant transcript. In leukemia, the

    Authors: Luiza Handschuh, Pawel Wojciechowski, Maciej Kazmierczak, Malgorzata Marcinkowska-Swojak, Magdalena Luczak, Krzysztof Lewandowski, Mieczyslaw Komarnicki, Jacek Blazewicz, Marek Figlerowicz and Piotr Kozlowski

    Citation: Journal of Translational Medicine 2018 16:232

    Published on:

  7. Content type: Research

    There is increasing interest in using extracellular vesicle-derived microRNAs (miRNAs) as biomarkers in renal dysfunction and injury. Preliminary evidence indicates that miRNAs regulate the progression of glom...

    Authors: Javier Perez-Hernandez, Dolores Olivares, Maria J. Forner, Ana Ortega, Elena Solaz, Fernando Martinez, Felipe J. Chaves, Josep Redon and Raquel Cortes

    Citation: Journal of Translational Medicine 2018 16:228

    Published on:

  8. Content type: Research

    Circulating exosomes from prostate cancer (PCa) patients undergoing radiotherapy are attractive candidate biomarkers for monitoring treatment response. Multiple workflows for isolation and content characteriza...

    Authors: Bijaya Malla, Daniel M. Aebersold and Alan Dal Pra

    Citation: Journal of Translational Medicine 2018 16:223

    Published on:

  9. Content type: Research

    MicroRNAs play roles in the pathogenesis of bronchial asthma. However, the mechanism of miR-29c in allergic asthma remains unclear. This study is to elucidate the regulation of Th cell differentiation by miR-2...

    Authors: Xinxing Zhang, Xin Zhao, Huiming Sun, Yongdong Yan, Li Huang, Wenjin Gu, Wujun Jiang, Yuqing Wang, Canhong Zhu, Wei Ji, Chuangli Hao and Zhengrong Chen

    Citation: Journal of Translational Medicine 2018 16:218

    Published on:

  10. Content type: Research

    Little has been known about the role of non-coding RNA regulatory network in the patterns of growth and invasiveness of gastric cancer (GC) development.

    Authors: Jia Cheng, Huiqin Zhuo, Mao Xu, Linpei Wang, Hao Xu, Jigui Peng, Jingjing Hou, Lingyun Lin and Jianchun Cai

    Citation: Journal of Translational Medicine 2018 16:216

    Published on:

  11. Content type: Research

    Membranous glomerulonephritis (MGN) is the most common cause of nephrotic syndrome in adult patients. Despite extensive evidences suggested that many immune-related genes could serve as effective biomarkers in...

    Authors: Chengwei Zhang, Lei Leng, Xiaoming Zhang, Yao Zhao and Zhaozheng Li

    Citation: Journal of Translational Medicine 2018 16:210

    Published on:

  12. Content type: Research

    The early and accurate diagnosis of tuberculosis (TB) is critical for controlling the global TB epidemic. Although early studies have supported the potential role of cytokine biomarkers in blood for the diagno...

    Authors: Sen Wang, Yang Li, Yaojie Shen, Jing Wu, Yan Gao, Shu Zhang, Lingyun Shao, Jialin Jin, Ying Zhang and Wenhong Zhang

    Citation: Journal of Translational Medicine 2018 16:206

    Published on:

  13. Content type: Research

    Abnormal microRNAs (miRNAs) were reported to be involved in the mechanism of Graves’ disease (GD). Dysregulated miRNAs may be overlapping in different cells and can be secreted to circulation. We chose miRNAs ...

    Authors: Xinxin Chen, Fengjiao Huang, Yicheng Qi, Mengxi Zhou, Qinglei Yin, Ying Peng, Yulin Zhou, Guang Ning and Shu Wang

    Citation: Journal of Translational Medicine 2018 16:188

    Published on:

  14. Content type: Research

    The functions of the protein expressed in the nucleus and cytoplasm were different or opposite. The previous study found that oncogene Klf4 played a role of tumor suppressor in the nasopharyngeal cytoplasm. Cetux...

    Authors: Xiqing Li, Zunlan Zhao, Shijiang Yi, Lei Ma, Ming Li, Mingyue Liu, Yaping Zhang and Guangzhi Liu

    Citation: Journal of Translational Medicine 2018 16:183

    Published on:

  15. Content type: Research

    Implantation failure is not only a major cause of early pregnancy loss, but it is also an obstacle to assisted reproductive technologies. The identification of potential circulating biomarkers for recurrent mi...

    Authors: Qian Yang, Wen-Wen Gu, Yan Gu, Na-Na Yan, Yan-Yan Mao, Xing-Xing Zhen, Jian-Mei Wang, Jing Yang, Hui-Juan Shi, Xuan Zhang and Jian Wang

    Citation: Journal of Translational Medicine 2018 16:186

    Published on:

  16. Content type: Research

    We previously reported early on-treatment significant modulation in circulating regulatory T cell (Treg), myeloid derived suppressor cells (MDSC) and antigen-specific type I CD4+ and CD8+ T cells that correlat...

    Authors: Janet Retseck, Alexis Nasr, Yan Lin, Huang Lin, Prateek Mendiratta, Lisa H. Butterfield and Ahmad A. Tarhini

    Citation: Journal of Translational Medicine 2018 16:184

    Published on:

  17. Content type: Research

    Patients with brain tumor or pancreatic cancer exhibit the poorest prognosis, while immune fitness and cellular immune exhaustion impacts their survival immensely. This work identifies differences in the immun...

    Authors: Zhenjiang Liu, Thomas Poiret, Qingda Meng, Martin Rao, Anna von Landenberg, Esther Schoutrop, Davide Valentini, Ernest Dodoo, Inti Peredo-Harvey and Markus Maeurer

    Citation: Journal of Translational Medicine 2018 16:182

    Published on:

  18. Content type: Research

    Circulating tumor cells (CTCs) have been suggested as potential prognostic indicators for multiple tumors, including gastric cancer; however, pre- and post-operative CTC changes in resectable gastric cancer an...

    Authors: Qiyue Zhang, Fei Shan, Ziyu Li, Jing Gao, Yilin Li, Lin Shen, Jiafu Ji and Ming Lu

    Citation: Journal of Translational Medicine 2018 16:171

    Published on:

  19. Content type: Research

    The carboxyl terminus of Hsc70-interacting protein (CHIP) is an E3 ubiquitin ligase that plays a controversial role in different cancers, either as a tumor suppressor or a tumor promoter. To date, the exact fu...

    Authors: Jingjing Xu, Jun Zhou, Hanjue Dai, Fei Liu, Wenjing Li, Wenjuan Wang and Feng Guo

    Citation: Journal of Translational Medicine 2018 16:169

    Published on:

  20. Content type: Research

    Symptomatic peripheral artery disease (PAD) is an atherosclerotic occlusive disease affecting the lower extremities. The cause of symptomatic PAD is atherosclerosis, vascular dysfunctions, impaired angiogenesi...

    Authors: Line Ea Hemstra, Anders Schlosser, Jes Sanddal Lindholt and Grith L. Sorensen

    Citation: Journal of Translational Medicine 2018 16:159

    Published on:

  21. Content type: Research

    Granulin epithelin precursor (GEP) is reported to function as a growth factor stimulating proliferation and migration, and conferring chemoresistance in many cancer types. However, the expression and functiona...

    Authors: Yi Pan, Siu Tim Cheung, Joanna Hung Man Tong, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon Siu Man Ng, Tony Wing Chung Mak, Ka Fai To and Anthony Wing Hung Chan

    Citation: Journal of Translational Medicine 2018 16:150

    Published on:

  22. Content type: Research

    Diabetic kidney disease is a renal microvascular disease caused by diabetes, known as one of the most serious and lethal complications of diabetes. Early renal hypertrophy is the main pathological feature, whi...

    Authors: Yue Wang, Zong-ji Zheng, Yi-jie Jia, Yan-lin Yang and Yao-ming Xue

    Citation: Journal of Translational Medicine 2018 16:146

    Published on:

  23. Content type: Research

    Increasing studies showed that miR-200 family (miR-200s) clusters are aberrantly expressed in multiple human cancers, and miR-200s clusters function as tumor suppressor genes by affecting cell proliferation, self...

    Authors: Jing-dong Zhou, Liu-chao Zhang, Ting-juan Zhang, Yu Gu, De-hong Wu, Wei Zhang, Ji-chun Ma, Xiang-mei Wen, Hong Guo, Jiang Lin and Jun Qian

    Citation: Journal of Translational Medicine 2018 16:135

    Published on:

  24. Content type: Research

    Prostate cancer (PCa) is a fatal malignant tumor among males in the world and the metastasis is a leading cause for PCa death. Biomarkers are therefore urgently needed to detect PCa metastatic signature at the...

    Authors: Yuxin Lin, Feifei Chen, Li Shen, Xiaoyu Tang, Cui Du, Zhandong Sun, Huijie Ding, Jiajia Chen and Bairong Shen

    Citation: Journal of Translational Medicine 2018 16:134

    Published on:

  25. Content type: Research

    Cancer and coagulation activation are tightly related. The extent to which factors related to both these pathologic conditions concur to patient prognosis intensely animates the inherent research areas. The st...

    Authors: Chiara Mandoj, Laura Pizzuti, Domenico Sergi, Isabella Sperduti, Marco Mazzotta, Luigi Di Lauro, Antonella Amodio, Silvia Carpano, Anna Di Benedetto, Claudio Botti, Francesca Ferranti, Anna Antenucci, Maria Gabriella D’Alessandro, Paolo Marchetti, Silverio Tomao, Giuseppe Sanguineti…

    Citation: Journal of Translational Medicine 2018 16:129

    Published on:

  26. Content type: Research

    Recently, accumulating evidences have revealed that microRNA-106 (miR-106) may serve as a non-invasive and cost-effective biomarker in gastric cancer (GC) detection. However, inconsistent results have prevente...

    Authors: Qiliang Peng, Yi Shen, Kaisu Lin, Li Zou, Yuntian Shen and Yaqun Zhu

    Citation: Journal of Translational Medicine 2018 16:127

    Published on:

  27. Content type: Research

    Intra-tumoral heterogeneity has been recently addressed in different types of cancer, including breast cancer. A concept describing the origin of intra-tumoral heterogeneity is the cancer stem-cell hypothesis,...

    Authors: Pascale Kündig, Charlotte Giesen, Hartland Jackson, Bernd Bodenmiller, Bärbel Papassotirolopus, Sandra Nicole Freiberger, Catharine Aquino, Lennart Opitz and Zsuzsanna Varga

    Citation: Journal of Translational Medicine 2018 16:118

    Published on:

    The Correction to this article has been published in Journal of Translational Medicine 2018 16:180

  28. Content type: Research

    A working group on the Oxford classification of IgA nephropathy (IgAN) recently reported that crescents detected in kidney tissue predicted a worse renal outcome. However, this finding must be validated in ind...

    Authors: Xiaoyan Zhang, Sufang Shi, Yan Ouyang, Meng Yang, Manman Shi, Xiaoxia Pan, Jicheng Lv, Zhaohui Wang, Hong Ren, Pingyan Shen, Weiming Wang, Hong Zhang, Jingyuan Xie and Nan Chen

    Citation: Journal of Translational Medicine 2018 16:115

    Published on:

  29. Content type: Research

    CA125 is a prevalently used serum biomarker for detecting ovarian cancer over the last three decades. However, it has a significant deficiency in screening for early-stage cancer. With the purpose of exploring...

    Authors: Zhuowei Gu, Yifeng He, Yue Zhang, Mo Chen, Keqi Song, Yuting Huang, Qing Li and Wen Di

    Citation: Journal of Translational Medicine 2018 16:114

    Published on:

  30. Content type: Research

    Nonalcoholic fatty liver disease (NAFLD) is a prevalent complication of extreme obesity. Loading of the liver with fat can progress to inflammation and fibrosis including cirrhosis. The molecular factors invol...

    Authors: Xin Chu, Qunyan Jin, Hui Chen, G. Craig Wood, Anthony Petrick, William Strodel, Jon Gabrielsen, Peter Benotti, Tooraj Mirshahi, David J. Carey, Christopher D. Still, Johanna K. DiStefano and Glenn S. Gerhard

    Citation: Journal of Translational Medicine 2018 16:108

    Published on:

  31. Content type: Research

    Human tissues are invaluable resources for researchers worldwide. Biobanks are repositories of such human tissues and can have a strategic importance for genetic research, clinical care, and future discoveries...

    Authors: Ehsan Ullah, Raghvendra Mall, Reda Rawi, Naima M. Moustaid, Adeel A. Butt and Halima Bensmail

    Citation: Journal of Translational Medicine 2018 16:99

    Published on:

  32. Content type: Research

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is clinically defined and characterised by persistent disabling tiredness and exertional malaise, leading to functional impairment.

    Authors: Alice M. Richardson, Don P. Lewis, Badia Kita, Helen Ludlow, Nigel P. Groome, Mark P. Hedger, David M. de Kretser and Brett A. Lidbury

    Citation: Journal of Translational Medicine 2018 16:97

    Published on:

  33. Content type: Research

    Urinary miRNAs may potentially serve as noninvasive biomarkers in various kidney diseases to reflect disease activity, severity and progression, especially those correlated with the pathogenesis of kidney dise...

    Authors: Changming Zhang, Shaoshan Liang, Shuiqin Cheng, Wei Li, Xia Wang, Chunxia Zheng, Caihong Zeng, Shaolin Shi, Lu Xie, Ke Zen and Zhihong Liu

    Citation: Journal of Translational Medicine 2018 16:91

    Published on:

  34. Content type: Review

    Squamous cell carcinoma (SCC) is well-known for its high rate of metastasis with poor prognosis. CD109 is a glycosylphosphatidylinositol-anchored cell-surface glycoprotein. Recently, CD109 emerges as a potenti...

    Authors: Ruixia Qi, Fengyun Dong, Qiang Liu, Yoshiki Murakumo and Ju Liu

    Citation: Journal of Translational Medicine 2018 16:88

    Published on:

  35. Content type: Research

    S100A9 protein, which is recently classified as a novel damage associated molecular pattern, is released from stressed cells undergoing necrosis or secreted by living cells undergoing a stress that act as endo...

    Authors: Rui Wu, Yuhong Zhang, Yu Xiang, Yishu Tang, Fang Cui, Ju Cao, Lan Zhou, Yan You and Liang Duan

    Citation: Journal of Translational Medicine 2018 16:83

    Published on:

  36. Content type: Research

    Telocytes (TCs), a recently discovered novel type of interstitial cells, were also found in a wide variety of human and mammalian reproductive organs/tissues, including uterus, oviduct and placenta. Previously...

    Authors: Xiao-Juan Jiang, Dragos Cretoiu, Zong-Ji Shen and Xiao-Jun Yang

    Citation: Journal of Translational Medicine 2018 16:85

    Published on:

  37. Content type: Research

    Immune checkpoint inhibitors (anti-CTLA-4, anti-PD-1, or the combination) enhance anti-tumor immune responses, yielding durable clinical benefit in several cancer types, including melanoma. However, a subset o...

    Authors: Michael F. Gowen, Keith M. Giles, Danny Simpson, Jeremy Tchack, Hua Zhou, Una Moran, Zarmeena Dawood, Anna C. Pavlick, Shaohui Hu, Melissa A. Wilson, Hua Zhong, Michelle Krogsgaard, Tomas Kirchhoff and Iman Osman

    Citation: Journal of Translational Medicine 2018 16:82

    Published on:

  38. Content type: Research

    Squamous cell carcinoma (SCC) of the conjunctiva is a common cancer in Africa mainly associated with solar ultraviolet (UV) exposure and human immunodeficiency virus (HIV) infection. We analyzed the role of HI...

    Authors: Noemy Starita, Luigi Buonaguro, Franco M. Buonaguro and Maria Lina Tornesello

    Citation: Journal of Translational Medicine 2018 16:77

    Published on:

  39. Content type: Research

    This study addresses whether the association of adiponectin gene (ADIPOQ) variants with idiopathic recurrent pregnancy loss (RPL) is influenced by obesity.

    Authors: Maryam Dendana, Wael Bahia, Ramzi R. Finan, Mariam Al-Mutawa and Wassim Y. Almawi

    Citation: Journal of Translational Medicine 2018 16:76

    Published on:

  40. Content type: Research

    Controversy exists in previous studies on macrophage M1/M2 polarization in chronic obstructive pulmonary disease (COPD). We hypothesized that formyl peptide receptor (FPR), a marker of efferocytosis and mediat...

    Authors: Yung-Che Chen, Meng-Chih Lin, Chih-Hung Lee, Shih-Feng Liu, Chin-Chou Wang, Wen-Feng Fang, Tung-Ying Chao, Chao-Chien Wu, Yu-Feng Wei, Huang-Chih Chang, Chia-Cheng Tsen and Hung-Chen Chen

    Citation: Journal of Translational Medicine 2018 16:69

    Published on:

  41. Content type: Research

    Human neutrophil antigen 3 (HNA-3) is encoded by the SLC44A2 gene. Antibodies against HNAs can cause severe, often fatal, transfusion reactions, known as transfusion-related acute lung injury, and neonatal neu...

    Authors: Guo-Jin Ou, Pin-Can Su, Hao Yu, Xin Ji, Fan Liu, Sheng-Lan Wang, Yu-Jie Kong, Ling Li, Jue Wang, Zhong Liu and Willy Albert Flegel

    Citation: Journal of Translational Medicine 2018 16:67

    Published on:

  42. Content type: Research

    MicroRNAs are of special interest in cancer research and hold significant promise as diagnostic and prognostic biomarkers for malignant disease. MiR-362-5p have been found to exert both oncogenic and tumor sup...

    Authors: Qiu-Ling Ma, Jing-Han Wang, Min Yang, Huan-ping Wang and Jie Jin

    Citation: Journal of Translational Medicine 2018 16:68

    Published on:

  43. Content type: Research

    Circulating microRNAs (miRNAs) are emerging as novel biomarkers for detecting cardiovascular diseases. In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting...

    Authors: Yong Song, Hilda Higgins, Jing Guo, Katrina Harrison, En Nee Schultz, Belinda J. Hales, Eric K. Moses, Jack Goldblatt, Nicholas Pachter and Guicheng Zhang

    Citation: Journal of Translational Medicine 2018 16:42

    Published on:

  44. Content type: Research

    An extensive crosstalk co-regulates the Hippo and Wnt pathway. Preclinical studies revealed that the Hippo transducers YAP/TAZ mediate a number of oncogenic functions in gastric cancer (GC). Moreover, comprehe...

    Authors: Elisa Melucci, Beatrice Casini, Livia Ronchetti, Laura Pizzuti, Francesca Sperati, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Enzo Gallo, Carla Azzurra Amoreo, Domenico Sergi, Irene Terrenato, Patrizia Vici, Luigi Di Lauro, Maria Grazia Diodoro, Edoardo Pescarmona…

    Citation: Journal of Translational Medicine 2018 16:22

    Published on:

  45. Content type: Research

    Dental caries is a major worldwide oral disease afflicting a large proportion of children. As an important host factor of caries susceptibility, saliva plays a significant role in the occurrence and developmen...

    Authors: Kun Wang, Yufei Wang, Xiuqing Wang, Qian Ren, Sili Han, Longjiang Ding, Zhongcheng Li, Xuedong Zhou, Wei Li and Linglin Zhang

    Citation: Journal of Translational Medicine 2018 16:11

    Published on:

  46. Content type: Research

    Bladder cancer (BCa) is one of the most common cancers in the urinary system among the world. Previous studies suggested that TMEM40 expression level was significantly associated with clinicopathological param...

    Authors: Zhen-Fei Zhang, Han-Rong Zhang, Qing-Yan Zhang, Shu-Yu Lai, Yu-Zhen Feng, Yi Zhou, Si-Rong Zheng, Rong Shi and Jue-Yu Zhou

    Citation: Journal of Translational Medicine 2018 16:9

    Published on:

  47. Content type: Research

    To screen tumors with microsatellite instability (MSI) arising due to DNA mismatch repair deficiency (dMMR), a panel of five quasi-monomorphic mononucleotide-repeat markers amplified in a multiplex PCR (Pentap...

    Authors: Yuko Takehara, Takeshi Nagasaka, Akihiro Nyuya, Tomoko Haruma, Junko Haraga, Yoshiko Mori, Keiichiro Nakamura, Toshiyoshi Fujiwara, C. Richard Boland and Ajay Goel

    Citation: Journal of Translational Medicine 2018 16:5

    Published on:

  48. Content type: Research

    Plasma extracellular vesicles (EVs), especially exosome-like vesicles (ELVs), are being increasingly explored as a source of potential noninvasive disease biomarkers. The discovery of blood-based biomarkers as...

    Authors: Ruzena Stranska, Laurens Gysbrechts, Jens Wouters, Pieter Vermeersch, Katarzyna Bloch, Daan Dierickx, Graciela Andrei and Robert Snoeck

    Citation: Journal of Translational Medicine 2018 16:1

    Published on:

  49. Content type: Research

    In our previous study, we revealed that MEG3 was a tumor suppressor gene in retinoblastoma and inhibited proliferation of retinoblastoma cells by regulating the activity of the Wnt/β-catenin pathway. Here, we ...

    Authors: Yali Gao, Peng Huang and Jun Zhang

    Citation: Journal of Translational Medicine 2017 15:268

    Published on:

  50. Content type: Research

    Sepsis represents a complex disease with the dysregulated inflammatory response and high mortality rate. The goal of this study was to identify potential transcriptomic markers in developing pediatric sepsis b...

    Authors: Yiping Li, Yanhong Li, Zhenjiang Bai, Jian Pan, Jian Wang and Fang Fang

    Citation: Journal of Translational Medicine 2017 15:254

    Published on:

2017 Journal Metrics

Advertisement