Skip to main content

Translational Craniofacial and Dental Medicine

Section edited by Giuseppe Intini

In recent years, several innovations in dental, oral, and craniofacial sciences have been commercialized, transforming clinical practice in the United States and throughout the world. These innovations have been supported by translational research in the fields of tissue regeneration, implantology, biomaterials, computer sciences, informatics, bioinformatics, and genetics. The Translational Craniofacial and Dental Medicine section, by disseminating novel research studies, aims to foster new discoveries in the field of Craniofacial and Dental Medicine.

We are interested in research that investigates innovative approaches in all craniofacial and dental specialties, including oral medicine and oral pathology. We will consider studies regarding therapeutic approaches for treatment of diseases and for tissue regeneration, biomaterials for restorative prosthesis and implantology, diagnostic tools, imaging, and large data analysis. Translational genomics and precision medicine studies that identify novel prognostic markers, tailored interventions, and prophylactic approaches are also welcome.

  1. Periodontitis is a major inflammatory disease of the oral mucosa that is not limited to the oral cavity but also has systemic consequences. Although the importance of chronic periodontitis has been emphasized,...

    Authors: Hansong Lee, Ji-Young Joo, Dong Hyun Sohn, Junho Kang, Yeuni Yu, Hae Ryoun Park and Yun Hak Kim
    Citation: Journal of Translational Medicine 2022 20:504
  2. MicroRNA (miRNA) is accepted as a critical regulator of cell differentiation. However, whether microRNA-223 (miR-223) could affect the osteogenic differentiation of periodontal ligament (PDL)-derived cells is ...

    Authors: Zheng Zhang, Minghui Wang, Youli Zheng, Yanmei Dai, Jiashu Chou, Xiaowei Bian, Pengcheng Wang, Changyi Li and Jing Shen
    Citation: Journal of Translational Medicine 2022 20:465
  3. In the last decades, the ortho-aesthetic-functional rehabilitation had significant advances with the advent of implantology. Despite the success in implantology surgeries, there is a percentage of failures mai...

    Authors: Carlos Henrique Alves, Karolayne Larissa Russi, Natália Conceição Rocha, Fábio Bastos, Michelle Darrieux, Thais Manzano Parisotto and Raquel Girardello
    Citation: Journal of Translational Medicine 2022 20:425
  4. Periodontitis is an inflammatory disease initiated by dysbiosis of the local microbial community. Periodontitis can result in destruction of tooth-supporting tissue; however, overactivation of the host immune ...

    Authors: Hongbing Lin, Huishan Chen, Xuetao Zhao, Tong Ding, Yawei Wang, Zhen Chen, Yue Tian, Peipei Zhang and Yuqin Shen
    Citation: Journal of Translational Medicine 2022 20:279
  5. Sclerostin is the protein product of the SOST gene and is known for its inhibitory effects on bone formation. The monoclonal antibody against sclerostin has been approved as a novel treatment method for osteoporo...

    Authors: Chufang Liao, Shanshan Liang, Yining Wang, Ting Zhong and Xiangning Liu
    Citation: Journal of Translational Medicine 2022 20:221
  6. Extracellular vesicles (EVs) play a key role in constructing a microenvironment that favors the differentiation of stem cells. The present work aimed to determine the molecular mechanisms by which EV derived f...

    Authors: Chaoting Yan, Na Li, Tong Xiao, Xiaying Ye, Lin Fu, Yu Ye, Tao Xu and Jinhua Yu
    Citation: Journal of Translational Medicine 2022 20:208
  7. Emerging evidence shows that periodontal disease (PD) may increase the risk of Coronavirus disease 2019 (COVID-19) complications. Here, we undertook a two-sample Mendelian randomization (MR) study, and investi...

    Authors: Yi Wang, Hui Deng, Yihuai Pan, Lijian Jin, Rongdang Hu, Yongyong Lu, Wenhai Deng, Weijian Sun, Chengshui Chen, Xian Shen and Xiu-Feng Huang
    Citation: Journal of Translational Medicine 2021 19:528

    The Letter to the Editor to this article has been published in Journal of Translational Medicine 2022 20:113

  8. Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment app...

    Authors: Hongbing Lin, Huishan Chen, Xuetao Zhao, Zhen Chen, Peipei Zhang, Yue Tian, Yawei Wang, Tong Ding, Lijing Wang and Yuqin Shen
    Citation: Journal of Translational Medicine 2021 19:456
  9. Dental implants are considered the gold standard replacement for missing natural teeth. The successful clinical performance of dental implants is due to their ability to osseointegrate with the surrounding bon...

    Authors: Noura M. AlOtaibi, Michael Dunne, Ashraf F. Ayoub and Kurt B. Naudi
    Citation: Journal of Translational Medicine 2021 19:276