Advertisement
Section edited by Luis F. Alguacil
The Neuroscience section aims to encourage publications that help to reduce the gap between basic preclinical science and medical applications for the patients in the neuroscience field.
Betel quid dependence is associated with functional connectivity changes of the anterior cingulate cortex: a resting-state fMRI study
Tao Liu, et alNGF eye-drops topical administration in patients with retinitis pigmentosa, a pilot study
Benedetto Falsini, et alDevelopment of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1
Sharon K Michelhaugh, et al
Research
Hearing loss and ovarian dysfunction are key features of Perrault syndrome (PRLTS) but the clinical and pathophysiological features of hearing impairment in PRLTS individuals have not been addressed. Mutations...
Journal of Translational Medicine 2017 15:25
Published on: 8 February 2017
Research
Studies have indicated that bone marrow stromal cell (BMSC) administration is a promising approach for stroke treatment. For our study, we chose sodium ferulate (SF) and n-butylidenephthalide (BP) combined with B...
Journal of Translational Medicine 2016 14:223
Published on: 28 July 2016
Research
Systemic inflammation, neurocognitive impairments, and morphologic brain changes are associated with obstructive sleep apnea (OSA). Understanding their longitudinal evolution and interactions after surgical tr...
Journal of Translational Medicine 2016 14:139
Published on: 17 May 2016
Research
Vagus nerve stimulation (VNS) has become the most common non-pharmacological treatment for intractable drug-resistant epilepsy. However, the contribution of VNS to neurological rehabilitation following stroke ...
Journal of Translational Medicine 2016 14:101
Published on: 27 April 2016
Research
It is generally acknowledged that drug dependence is connected with abnormal functional organization in the individual’s brain. The present study aimed to identify the anterior cingulate cortex (ACC) abnormali...
Journal of Translational Medicine 2016 14:33
Published on: 2 February 2016
Research
Autosomal recessive non-syndromic hearing loss (ARNSHL) is highly heterogeneous, and mutations in the gene encoding transmembrane channel-like 1 (TMC1) have been implicated in its development. To date, 35 homo...
Journal of Translational Medicine 2016 14:29
Published on: 28 January 2016
Research
Preclinical trials have shown beneficial effects of nerve growth factor (NGF) administration on visual function in animal models of retinitis pigmentosa (RP). The aim of this pilot study was to explore the po...
Journal of Translational Medicine 2016 14:8
Published on: 9 January 2016
The Erratum to this article has been published in Journal of Translational Medicine 2016 14:43
Research
Parkinson’s disease (PD) is well documented to be associated with elevated systemic oxidative stress and perceptual impairments. Furthermore, the striatum and extrastriatal cortical areas, which are involved i...
Journal of Translational Medicine 2015 13:386
Published on: 21 December 2015
Research
Autophagy is demonstrated to be involved in acute ischemic stroke(AIS), which, however, is confined to cells and/or animals levels. The aim of this study was to determine two autophagy biomarkers, Beclin1 and ...
Journal of Translational Medicine 2015 13:359
Published on: 14 November 2015
Research
There is a paucity of effective therapies for recurrent/aggressive meningiomas. Establishment of improved in vitro and in vivo meningioma models will facilitate development and testing of novel therapeutic app...
Journal of Translational Medicine 2015 13:227
Published on: 15 July 2015
Research
Schizophrenia is a widespread and debilitating mental disorder. However, the underlying molecular mechanism of schizophrenia remains largely unknown and no objective laboratory tests are available to diagnose ...
Journal of Translational Medicine 2015 13:226
Published on: 14 July 2015
Research
Rodents are incapable of emesis and consequently the emetic potential of glucagon-like peptide-1 receptor (GLP-1R) agonists in studies designed to assess a potential blood glucose lowering action of the compou...
Journal of Translational Medicine 2014 12:327
Published on: 10 December 2014
Research
A cochlear implant (CI) is an artificial hearing device that can replace a damaged cochlea. The present study examined the use of growth factor-eluting gelatin hydrogel coatings on the electrodes to minimize i...
Journal of Translational Medicine 2014 12:280
Published on: 4 October 2014
Research
our objective was to examine the plasma levels of three biological markers involved in cerebral ischemia (IL-6, glutamate and TNF-alpha) in stroke patients and compare them with two different rat models of foc...
Journal of Translational Medicine 2014 12:220
Published on: 3 August 2014
Research
Prevailingly, adult mammalian neurogenesis is thought to occur in discrete, separate locations known as neurogenic niches that are best characterized in the subgranular zone (SGZ) of the dentate gyrus and in t...
Journal of Translational Medicine 2014 12:75
Published on: 22 March 2014
Research
Racial and regional factors are important for the clinical diagnosis of non-syndromic hearing impairment. Comprehensive genetic analysis of deaf patients in different regions of China must be performed to prov...
Journal of Translational Medicine 2014 12:64
Published on: 11 March 2014
Research
Inherited genetic defects play an important role in congenital hearing loss, contributing to about 60% of deafness occurring in infants. Hereditary nonsyndromic hearing loss is highly heterogeneous, and most p...
Journal of Translational Medicine 2013 11:284
Published on: 9 November 2013
Research
MicroRNAs have recently emerged as key regulators of cancers, miR-329 located on 14q32.31 is one of down-regulated miRNAs in glioma, but the function and molecular mechanisms of miR-329 in determining the mali...
Journal of Translational Medicine 2013 11:172
Published on: 17 July 2013
Research
When patients with ocular motor deficits come to the clinic, in numerous situations it is hard to relate their behavior to one or several deficient neural structures. We sought to demonstrate that neuromimetic...
Journal of Translational Medicine 2013 11:125
Published on: 22 May 2013
Methodology
Neurodegenerative diseases such as Alzheimer’s are associated with the aggregation of endogenous peptides and proteins that contribute to neuronal dysfunction and loss. The glymphatic system, a brain-wide peri...
Journal of Translational Medicine 2013 11:107
Published on: 1 May 2013
