Skip to main content

Articles

Page 1 of 109

  1. Adipose tissue-derived adipokines are involved in various crosstalk between adipose tissue and other organs. Omentin1, a novel adipokine, exerts vital roles in the maintenance of body metabolism, insulin resis...

    Authors: Jingui Hu, Tao Liu, Fei Fu, Zekun Cui, Qiong Lai, Yuanyuan Zhang, Boyang Yu, Fuming Liu, Junping Kou and Fang Li
    Citation: Journal of Translational Medicine 2022 20:447
  2. Metastasis is the primary cause of cancer-related mortality. Metastasis involves a complex multistep process during which individual tumor cells spread primarily through destruction of the endothelial barrier,...

    Authors: Guoxin Zhang, Mengyuan Li, Dandan Zhou, Xingjiu Yang, Wenlong Zhang and Ran Gao
    Citation: Journal of Translational Medicine 2022 20:446
  3. According to the Global Cancer Statistics in 2020, the incidence and mortality of colorectal cancer (CRC) rank third and second among all tumors. The disturbance of ubiquitination plays an important role in th...

    Authors: Wei Zhang, Yan Yang, Liewen Lin, Jingquan He, Jingjing Dong, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Fanna Liu and Yong Dai
    Citation: Journal of Translational Medicine 2022 20:445
  4. Adrenocortical carcinoma (ACC) is an extremely rare, aggressive tumor with few effective therapeutic options or drugs. Mitotane (Mtn), which is the only authorized therapeutic drug, came out in 1970 and is sti...

    Authors: Liwen Ren, Yihui Yang, Wan Li, Xiangjin Zheng, Jinyi Liu, Sha Li, Hong Yang, Yizhi Zhang, Binbin Ge, Sen Zhang, Weiqi Fu, Dexin Dong, Guanhua Du and Jinhua Wang
    Citation: Journal of Translational Medicine 2022 20:444
  5. Gliomas account for about 80% of all malignant brain and other central nervous system (CNS) tumors. Temozolomide (TMZ) resistance represents a major treatment hurdle. Adrenomedullin (ADM) has been reported to ...

    Authors: Zongze He, Meixiong Cheng, Junting Hu, Lingtong Liu, Ping Liu, Longyi Chen, Deqian Cao and Jian Tang
    Citation: Journal of Translational Medicine 2022 20:443
  6. Advances in our understanding of the tumor microenvironment have radically changed the cancer field, highlighting the emerging need for biomarkers of an active, favorable tumor immune phenotype to aid treatmen...

    Authors: Shimaa Sherif, Raghvendra Mall, Hossam Almeer, Adviti Naik, Abdulaziz Al Homaid, Remy Thomas, Jessica Roelands, Sathiya Narayanan, Mahmoud Gasim Mohamed, Shahinaz Bedri, Salha Bujassoum Al-Bader, Kulsoom Junejo, Davide Bedognetti, Wouter Hendrickx and Julie Decock
    Citation: Journal of Translational Medicine 2022 20:442
  7. This study incorporates the results of subgroup analyses of currently published randomized controlled trials (RCTs) and real-world cohort studies to compare the effectiveness and safety of new direct oral anti...

    Authors: Xuedong Jia, Zhao Yin, Wan Zhang, Shuzhang Du and Jian Kang
    Citation: Journal of Translational Medicine 2022 20:441
  8. Glioblastoma (GBM) is the most common primary malignant brain tumor that leads to lethality. Several studies have demonstrated that mitochondria play an important role in GBM and that mitochondria-related gene...

    Authors: Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin and Yang Li
    Citation: Journal of Translational Medicine 2022 20:440
  9. Globally, gastric cancer is the third most common cancer and the third leading cause of cancer death. Proximal and distal gastric cancers have distinct clinical and biological behaviors. The microbial composit...

    Authors: Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang and Lisong Teng
    Citation: Journal of Translational Medicine 2022 20:439
  10. Diverse drug vulnerabilities owing to the Chromatin regulators (CRs) genetic interaction across various cancers, but the identification of CRs genetic interaction remains challenging.

    Authors: Bo Chen, Pengfei Li, Mingyue Liu, Kaidong Liu, Min Zou, Yiding Geng, Shuping Zhuang, Huanhuan Xu, Linzhu Wang, Tingting Chen, Yawei Li, Zhangxiang Zhao, Lishuang Qi and Yunyan Gu
    Citation: Journal of Translational Medicine 2022 20:438
  11. Metabolic disturbance has been reported in patients with epilepsy. Still, the evidence about the causal role of metabolites in facilitating or preventing epilepsy is lacking. Systematically investigating the c...

    Authors: Jiahao Cai, Xiaoyu Li, Shangbin Wu, Yang Tian, Yani Zhang, Zixin Wei, Zixiang Jin, Xiaojing Li, Xiong Chen and Wen-Xiong Chen
    Citation: Journal of Translational Medicine 2022 20:437
  12. The clinical observation showed a potential additive effect of anti-PD-1 agents and cetirizine in patients with advanced melanoma.

    Authors: Domenico Mallardo, Ester Simeone, Vito Vanella, Maria Grazia Vitale, Marco Palla, Luigi Scarpato, Miriam Paone, Teresa De Cristofaro, Valentina Borzillo, Alessio Cortellini, Francesca Sparano, Sandro Pignata, Francesco Fiore, Corrado Caracò, Piera Maiolino, Antonella Petrillo…
    Citation: Journal of Translational Medicine 2022 20:436
  13. Nephrectomy is considered the backbone of managing patients with localized and selected metastatic renal cell carcinoma (mRCC). The prognostic role of nephrectomy has been widely investigated with cytokines an...

    Authors: Sara Elena Rebuzzi, Alessio Signori, Giuseppe Luigi Banna, Annalice Gandini, Giuseppe Fornarini, Alessandra Damassi, Marco Maruzzo, Ugo De Giorgi, Umberto Basso, Silvia Chiellino, Luca Galli, Paolo Andrea Zucali, Emanuela Fantinel, Emanuele Naglieri, Giuseppe Procopio, Michele Milella…
    Citation: Journal of Translational Medicine 2022 20:435
  14. Gallbladder cancer (GBC) is a highly aggressive malignant cancer in the biliary system with poor prognosis. XPO1 (chromosome region maintenance 1 or CRM1) mediates the nuclear export of several proteins, mainl...

    Authors: Cheng Zhao, Zi-yi Yang, Jian Zhang, Ou Li, Shi-lei Liu, Chen Cai, Yi-jun Shu, Li-jia Pan, Wei Gong and Ping Dong
    Citation: Journal of Translational Medicine 2022 20:434
  15. The immune checkpoint inhibitors (ICIs) combined with other therapeutic strategies have shown exciting results in various malignancies, and ICIs have now become the gold standard for current cancer treatment. ...

    Authors: Dong Shao, Yaping Chen, Hao Huang, Yingting Liu, Junjun Chen, Dawei Zhu, Xiao Zheng, Lujun Chen and Jingting Jiang
    Citation: Journal of Translational Medicine 2022 20:433
  16. Chimeric antigen receptor (CAR)-T cell therapy is a powerful adoptive immunotherapy against both B-cell malignancies and some types of solid tumors. Interleukin (IL) -15 is an important immune stimulator that ...

    Authors: Ying Zhang, Qinghui Zhuang, Fang Wang, Can Zhang, Chang Xu, Aiqin Gu, William H. Zhong, Yi Hu and Xiaosong Zhong
    Citation: Journal of Translational Medicine 2022 20:432
  17. The pathogenesis of kidney stone disease (KSD) is not fully understood, and potential contributing factors remain to be explored. Several studies have revealed that the urinary microbiome (urobiome) of stone f...

    Authors: Sen-Yuan Hong, Yuan-Yuan Yang, Jin-Zhou Xu, Qi-Dong Xia, Shao-Gang Wang and Yang Xun
    Citation: Journal of Translational Medicine 2022 20:431
  18. Akkermansia muciniphila (A. muciniphila) is present in the human gut microbiota from infancy and gradually increases in adulthood. The potential impact of the abundance of A. muciniphila has been studied in major...

    Authors: Arun Prasath Lakshmanan, Selvasankar Murugesan, Souhaila Al Khodor and Annalisa Terranegra
    Citation: Journal of Translational Medicine 2022 20:430
  19. Patients with long-COVID often complain of continuous fatigue, myalgia, sleep problems, cognitive dysfunction, and post-exertional malaise. No data are available on EMG recording of evoked myopotentials (M-wav...

    Authors: Frédérique Retornaz, Stanislas Rebaudet, Chloé Stavris and Yves Jammes
    Citation: Journal of Translational Medicine 2022 20:429
  20. Osteoarthritis (OA) is the most common type of degenerative arthritis and affects the entire joint, causing pain, joint inflammation, and cartilage damage. Various risk factors are implicated in causing OA, an...

    Authors: Hyun Sik Na, Seon-Yeong Lee, Dong Hwan Lee, Jin Seok Woo, Si-Young Choi, Keun-Hyung Cho, Seon Ae Kim, Eun Jeong Go, A Ram Lee, Jeong-Won Choi, Seok Jung Kim and Mi-La Cho
    Citation: Journal of Translational Medicine 2022 20:428
  21. Long non-coding RNAs (lncRNAs) are closely related to the occurrence and development of cancer. Abnormally expressed lncRNA can be used as a diagnostic marker for cancer. In this study, we aim to investigate t...

    Authors: Jun Wang, Yuan Xiang, Sheng-Xi Yang, Hui-Min Zhang, Hui Li, Qi-Bei Zong, Le-Wei Li, Li-Li Zhao, Ruo-Han Xia, Chao Li, Le-Yuan Bao, Tong-Cun Zhang and Xing-Hua Liao
    Citation: Journal of Translational Medicine 2022 20:426
  22. In the last decades, the ortho-aesthetic-functional rehabilitation had significant advances with the advent of implantology. Despite the success in implantology surgeries, there is a percentage of failures mai...

    Authors: Carlos Henrique Alves, Karolayne Larissa Russi, Natália Conceição Rocha, Fábio Bastos, Michelle Darrieux, Thais Manzano Parisotto and Raquel Girardello
    Citation: Journal of Translational Medicine 2022 20:425
  23. Detecting trans-ethnic common associated genetic loci can offer important insights into shared genetic components underlying complex diseases/traits across diverse continental populations. However, effective s...

    Authors: Jiahao Qiao, Zhonghe Shao, Yuxuan Wu, Ping Zeng and Ting Wang
    Citation: Journal of Translational Medicine 2022 20:424
  24. The diversity of histologic composition reflects the inter- and intra-tumor heterogeneity of lung adenocarcinomas (LUADs) macroscopically. Insights into the oncological characteristics and tumor microenvironme...

    Authors: Dianke Li, Huansha Yu, Junjie Hu, Shaoling Li, Yilv Yan, Shuangyi Li, Liangdong Sun, Gening Jiang, Likun Hou, Lele Zhang and Peng Zhang
    Citation: Journal of Translational Medicine 2022 20:423
  25. Currently, there is no regenerative therapy for patients with neurological and neurodegenerative disorders. Cell-therapies have emerged as a potential treatment for numerous brain diseases. Despite recent adva...

    Authors: Ruslan Rust, Rebecca Z. Weber, Melanie Generali, Debora Kehl, Chantal Bodenmann, Daniela Uhr, Debora Wanner, Kathrin J. Zürcher, Hirohide Saito, Simon P. Hoerstrup, Roger M. Nitsch and Christian Tackenberg
    Citation: Journal of Translational Medicine 2022 20:421
  26. Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) worldwide. SGLT2 inhibitors are clinically effective in halting DKD progression. However, the underlying mechanisms remain u...

    Authors: Yong-Ping Lu, Ze-Yu Zhang, Hong-Wei Wu, Li-Jing Fang, Bo Hu, Chun Tang, Yi-Qing Zhang, Lianghong Yin, Dong-E. Tang, Zhi-Hua Zheng, Ting Zhu and Yong Dai
    Citation: Journal of Translational Medicine 2022 20:420
  27. This clinical trial evaluated a novel telomerase-targeting therapeutic cancer vaccine, UV1, in combination with ipilimumab, in patients with metastatic melanoma. Translational research was conducted on patient...

    Authors: Espen Basmo Ellingsen, Gergana Bounova, Iliana Kerzeli, Irantzu Anzar, Donjete Simnica, Elin Aamdal, Tormod Guren, Trevor Clancy, Artur Mezheyeuski, Else Marit Inderberg, Sara M. Mangsbo, Mascha Binder, Eivind Hovig and Gustav Gaudernack
    Citation: Journal of Translational Medicine 2022 20:419
  28. Neuroligins are postsynaptic cell adhesion molecules that are relevant to many neurodevelopmental disorders. They are differentially enriched at the postsynapse and interact with their presynaptic ligands, neu...

    Authors: Xing Liu, Fuzhou Hua, Danying Yang, Yue Lin, Lieliang Zhang, Jun Ying, Hongguang Sheng and Xifeng Wang
    Citation: Journal of Translational Medicine 2022 20:418
  29. The association between body mass index (BMI) and Alzheimer's disease (AD) remains controversial. Genetic and environmental factors are now considered contributors to AD risk. However, little is known about th...

    Authors: Shiqi Yuan, Wentao Wu, Wen Ma, Xiaxuan Huang, Tao Huang, MIn Peng, Anding Xu and Jun Lyu
    Citation: Journal of Translational Medicine 2022 20:417
  30. Bowen's disease is a cutaneous squamous cell carcinoma (CSCC) in situ. If left untreated, BD may progress to invasive CSCC. CSCC is one of the most common cutaneous carcinoma in the elderly and the advanced, m...

    Authors: Tang Biao, He Cai-feng, Lu Xiao-hong, Chang Xiao-li, Liu Wen-bei, Wang Jun, Ci Chao and Yuan Tao
    Citation: Journal of Translational Medicine 2022 20:416
  31. Colorectal cancer (CRC) is one of the most common malignancies and the patient survival rate remains unacceptably low. The anti-programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) antibody-ba...

    Authors: Lian-sheng Cheng, Yong-feng Cheng, Wen-ting Liu, Aolin Shen, Dayan Zhang, Tingjuan Xu, Wu Yin, Min Cheng, Xiaopeng Ma, Fengrong Wang, Qun Zhao, Xiaoli Zeng, Yan Zhang and Guodong Shen
    Citation: Journal of Translational Medicine 2022 20:415
  32. To figure out the functions of thymic stromal lymphopoietin (TSLP) in IgG4-related disease (IgG4-RD).

    Authors: Hui Lu, Xunyao Wu, Yu Peng, Ruijie Sun, Yuxue Nie, Jingna Li, Mu Wang, Yaping Luo, Linyi Peng, Yunyun Fei, Jiaxin Zhou, Wen Zhang and Xiaofeng Zeng
    Citation: Journal of Translational Medicine 2022 20:414
  33. Next generation sequencing (NGS) of human specimen is expected to improve prognosis and diagnosis of human diseases, but its sensitivity urges for well-defined sampling and standardized protocols in order to a...

    Authors: Uwe Michel, Orr Shomroni, Barbara Müller, Peter Lange, Gabriela Salinas, Mathias Bähr and Jan Christoph Koch
    Citation: Journal of Translational Medicine 2022 20:413
  34. Berberine (BBR), an isoquinoline alkaloid isolated from Rhizoma Coptis, is widely used in the treatment of hyperlipidemia (HLP) in China. At present, the efficacy of BBR against HLP is relatively clear, but th...

    Authors: Yuting Chen, Kaipeng Li, Han Zhao, Zhangsen Hao, Yuxin Yang, Mingming Gao and Ding Zhao
    Citation: Journal of Translational Medicine 2022 20:412
  35. Authors: Jonathan T. Sims, Ching-Yun Chang, Josh Poorbaugh, Montanea Daniels, Stephanie L. Beasley, Lin Zhang, George H. Rodgers, Fabio Lena, Leonardo G. Lacerenza, Bruno Sposato, Annabelle Dupont, Sophie Susen, Giacomo Casalini, Mario Corbellino, Justin Stebbing and Venkatesh Krishnan
    Citation: Journal of Translational Medicine 2022 20:411
  36. With the development of digital pathology and the renewal of deep learning algorithm, artificial intelligence (AI) is widely applied in tumor pathology. Previous researches have demonstrated that AI-based tumo...

    Authors: Zefeng Shen, Jintao Hu, Haiyang Wu, Zeshi Chen, Weixia Wu, Junyi Lin, Zixin Xu, Jianqiu Kong and Tianxin Lin
    Citation: Journal of Translational Medicine 2022 20:409
  37. Atrial fibrosis plays a critical role in the development of atrial fibrillation (AF). Exosomes are a promising cell-free therapeutic approach for the treatment of AF. The purposes of this study were to explore...

    Authors: Hongting Hao, Sen Yan, Xinbo Zhao, Xuejie Han, Ning Fang, Yun Zhang, Chenguang Dai, Wenpeng Li, Hui Yu, Yunlong Gao, Dingyu Wang, Qiang Gao, Yu Duan, Yue Yuan and Yue Li
    Citation: Journal of Translational Medicine 2022 20:407
  38. Glucocorticoid signalling is closely related to both epilepsy and associated cognitive impairment, possibly through mechanisms involving neuronal apoptosis. As a critical enzyme for glucocorticoid action, the ...

    Authors: Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin, Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C. Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li and Xinshi Wang
    Citation: Journal of Translational Medicine 2022 20:406
  39. Second primary malignancy (SPM) represents the leading long-term cause of death among patients with index head and neck squamous cell carcinoma (HNSCC). We aimed to quantify the association between postoperati...

    Authors: Xiaoke Zhu, Jian Zhou, Liang Zhou, Ming Zhang, Chunli Gao and Lei Tao
    Citation: Journal of Translational Medicine 2022 20:405
  40. Microparticles (MPs) are 100–1000 nm heterogeneous submicron membranous vesicles derived from various cell types that express surface proteins and antigenic profiles suggestive of their cellular origin. MPs co...

    Authors: Yu Liu, Sufei Wang, Hui Xia, Xueyun Tan, Siwei Song, Shujing Zhang, Daquan Meng, Qing Chen and Yang Jin
    Citation: Journal of Translational Medicine 2022 20:404
  41. The role of germline genetic factors in determining survival from cutaneous melanoma (CM) is not well understood.

    Authors: Mathias Seviiri, Richard A. Scolyer, D. Timothy Bishop, Julia A. Newton-Bishop, Mark M. Iles, Serigne N. Lo, Johnathan R. Stretch, Robyn P. M. Saw, Omgo E. Nieweg, Kerwin F. Shannon, Andrew J. Spillane, Scott D. Gordon, Catherine M. Olsen, David C. Whiteman, Maria Teresa Landi, John F. Thompson…
    Citation: Journal of Translational Medicine 2022 20:403
  42. Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer-related deaths worldwide. Aberrant cellular metabolism is a hallmark of cancer cells, and disturbed metabolism showed clinica...

    Authors: Zhan Wang, Miao-Miao Wang, Yan Geng, Chen-Yang Ye and Yuan-Sheng Zang
    Citation: Journal of Translational Medicine 2022 20:402
  43. Omega-3 may alleviate the severity of coronavirus disease 2019 (COVID-19) by reducing the C-reactive protein (CRP) level, a marker for systemic inflammation. Because the scientific evidence indicating such a r...

    Authors: Amira Mohamed Taha, Ahmad Shehata Shaarawy, Mohamed Mosad Omar, Khaled Abouelmagd, Noran Magdy Shalma, Mais Alhashemi, Hala Mahmoud Ahmed, Ahmed Hafez Allam and Mohamed Abd-ElGawad
    Citation: Journal of Translational Medicine 2022 20:401
  44. An imbalance in the expression of vascular endothelial growth factor (VEGF) and its receptor (VEGF-R) during pregnancy plays an important role in the pathogenesis of gestational diabetes mellitus (GDM) and ecl...

    Authors: Alayi Bolatai, Yujing He and Na Wu
    Citation: Journal of Translational Medicine 2022 20:400
  45. Peripheral biomarkers are increasingly vital non-invasive methods for monitoring coronary artery disease (CAD) progression. Their superiority in early detection, prognosis evaluation and classified diagnosis i...

    Authors: Xiaoteng Feng, Yifan Zhang, Min Du, Sijin Li, Jie Ding, Jiarou Wang, Yiru Wang and Ping Liu
    Citation: Journal of Translational Medicine 2022 20:399
  46. By identifying individuals at high risk for non-alcoholic fatty liver disease (NAFLD), interventional programs could be targeted more effectively. Some studies have demonstrated that triglyceride glucose-body ...

    Authors: Haofei Hu, Yong Han, Changchun Cao and Yongcheng He
    Citation: Journal of Translational Medicine 2022 20:398

Annual Journal Metrics