Skip to content


Journal of Translational Medicine

Cardiovascular, metabolic and Lipoprotein translation

Section edited by Nehal N. Mehta

This section aims to speed mechanistic understanding, development of novel diagnostics and potential therapeutic targets within cardiovascular, metabolic diseases and lipoprotein diseases. The section is open to experiments involving cellular models, animal models, observational studies and clinical trials that are distinguished for their novelty in approach, design or indication, timeliness, and unique ability to translate laboratory concepts from the bench to the bedside.

Highest priority will be given to those manuscripts which are specifically focused on cardiovascular, metabolic and lipid disorders which enrich understanding of disease mechanism, novel therapeutics and state-of-the-art scientific technique.

Previous Page Page 1 of 8 Next Page
  1. Content type: Research

    MicroRNAs (miRNAs) are small RNAs regulating gene expression post-transcriptionally. While acquired changes of miRNA and mRNA profiles in cancer have been extensively studied, little is known about expression ...

    Authors: Masood Abu-Halima, Mustafa Kahraman, Dominic Henn, Tanja Rädle-Hurst, Andreas Keller, Hashim Abdul-Khaliq and Eckart Meese

    Citation: Journal of Translational Medicine 2018 16:60

    Published on:

  2. Content type: Research

    There is a preponderance of evidence implicating diabetes with increased coronary artery disease (CAD) and calcification (CAC) in human patients with metabolic syndrome (MetS), but the effect of diabetes on CA...

    Authors: Jill K. Badin, Ayeeshik Kole, Benjamin Stivers, Victor Progar, Anisha Pareddy, Mouhamad Alloosh and Michael Sturek

    Citation: Journal of Translational Medicine 2018 16:58

    Published on:

  3. Content type: Research

    Familial hypercholesterolemia (FH) is a genetic disorder that result in abnormally high low-density lipoprotein cholesterol levels, markedly increased risk of coronary heart disease (CHD) and tendon xanthomas ...

    Authors: Lucía Baila-Rueda, Itziar Lamiquiz-Moneo, Estíbaliz Jarauta, Rocío Mateo-Gallego, Sofía Perez-Calahorra, Victoria Marco-Benedí, Ana M. Bea, Ana Cenarro and Fernando Civeira

    Citation: Journal of Translational Medicine 2018 16:6

    Published on:

  4. Content type: Research

    Metabolic syndrome (MetS) is a highly prevalent condition that identifies individuals at risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. Prevention of these diseases relies on ear...

    Authors: Michelle D. Robinson, Ina Mishra, Sneha Deodhar, Vipulkumar Patel, Katrina V. Gordon, Raul Vintimilla, Kim Brown, Leigh Johnson, Sid O’Bryant and David P. Cistola

    Citation: Journal of Translational Medicine 2017 15:258

    Published on:

  5. Content type: Review

    Spondylarthritis (SpA) is an inflammatory rheumatic disease associated with increased incidence of major adverse cardiovascular events (MACEs). Recently, Paramarta et al. proposed the use of the tyrosine kinas...

    Authors: Loukman Omarjee, Vincent Jaquinandi and Guillaume Mahe

    Citation: Journal of Translational Medicine 2017 15:255

    Published on:

  6. Content type: Research

    Image-guided high intensity focused ultrasound has been used as an extracorporeal cardiac pacing tool and to enhance homing of stem cells to targeted tissues. However, molecular changes in the myocardium after...

    Authors: Kee W. Jang, Tsang-Wei Tu, Matthew E. Nagle, Bobbi K. Lewis, Scott R. Burks and Joseph A. Frank

    Citation: Journal of Translational Medicine 2017 15:252

    Published on:

  7. Content type: Review

    GlycA is a novel spectroscopic marker of systemic inflammation with low intra-individual variability and other attributes favoring its clinical use in patients with chronic inflammatory and autoimmune diseases...

    Authors: Margery A. Connelly, James D. Otvos, Irina Shalaurova, Martin P. Playford and Nehal N. Mehta

    Citation: Journal of Translational Medicine 2017 15:219

    Published on:

  8. Content type: Research

    Ex-vivo normothermic perfusion strategies are a promising new instrument in organ transplantation. The perfusion conditions are designed to be protective however the artificial environment can induce a local i...

    Authors: Sarah A. Hosgood, Tom Moore, Theresa Kleverlaan, Tom Adams and Michael L. Nicholson

    Citation: Journal of Translational Medicine 2017 15:216

    Published on:

  9. Content type: Research

    Renal denervation (RDN) is a promising therapeutic method in cardiology. Its currently most investigated indication is resistant hypertension. Other potential indications are atrial fibrillation, type 2 diabet...

    Authors: Jean-Claude Lubanda, Miroslav Chochola, Mikuláš Mlček, Petr Neužil, Josef Marek, Štěpán Havránek, Sylvie Kuchynková, Zdeňka Fingrová, Kao-Hsuan Aimee Huang and Aleš Linhart

    Citation: Journal of Translational Medicine 2017 15:215

    Published on:

  10. Content type: Research

    Meaningful translational large animal models for cardiac diseases are indispensable for studying disease mechanisms, development of novel therapeutic strategies, and evaluation of potential drugs.

    Authors: Mariann Gyöngyösi, Noemi Pavo, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Georg Goliasch, Ljubica Mandic, Jutta Bergler-Klein, Alfred Gugerell, Andras Jakab, Zsuzsanna Szankai, Levente Toth, Rita Garamvölgyi, Gerald Maurer, Frederic Jaisser…

    Citation: Journal of Translational Medicine 2017 15:202

    Published on:

  11. Content type: Research

    MicroRNAs (miRNAs) are a class of regulatory RNAs that regulate gene expression post-transcriptionally. Little, however, is known on the expression profile of circulating miRNAs in Tetralogy of Fallot (TOF) pa...

    Authors: Masood Abu-Halima, Eckart Meese, Andreas Keller, Hashim Abdul-Khaliq and Tanja Rädle-Hurst

    Citation: Journal of Translational Medicine 2017 15:156

    Published on:

  12. Content type: Protocol

    Regular physical activity is recommended for patients with chronic heart failure to improve their functional capacity, and walking is a popular, effective, and safe form of physical activity. Pedometers have s...

    Authors: Tomas Vetrovsky, Michal Siranec, Jiri Parenica, Martin Griva, Jiri Stastny, Jan Precek, Radek Pelouch, Vaclav Bunc, Ales Linhart and Jan Belohlavek

    Citation: Journal of Translational Medicine 2017 15:153

    Published on:

  13. Content type: Research

    Diabetic nephropathy (DN) is a severe complication of diabetes mellitus (DM). Pancreas or islet transplantation has been reported to prevent the development of DN lesions and ameliorate or reverse existing glo...

    Authors: Yongwei Jiang, Wenjian Zhang, Shiqing Xu, Hua Lin, Weiguo Sui, Honglin Liu, Liang Peng, Qing Fang, Li Chen and Jinning Lou

    Citation: Journal of Translational Medicine 2017 15:147

    Published on:

  14. Content type: Research

    Radiolabeled RGD peptides detect αvβ3 integrin expression associated with angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied whether cardiac positron emission tomography (PET...

    Authors: Maria Grönman, Miikka Tarkia, Tuomas Kiviniemi, Paavo Halonen, Antti Kuivanen, Timo Savunen, Tuula Tolvanen, Jarmo Teuho, Meeri Käkelä, Olli Metsälä, Mikko Pietilä, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Anne Roivainen and Antti Saraste

    Citation: Journal of Translational Medicine 2017 15:144

    Published on:

  15. Content type: Research

    The endothelium is a key variable in the pathogenesis of atherosclerosis and its complications, particularly coronary artery disease (CAD). Current evidence suggests that the endothelial status can be regarded...

    Authors: Martino Deidda, Cristina Piras, Christian Cadeddu Dessalvi, Damiana Congia, Emanuela Locci, Federica Ascedu, Gianfranco De Candia, Mauro Cadeddu, Giorgio Lai, Raimondo Pirisi, Luigi Atzori and Giuseppe Mercuro

    Citation: Journal of Translational Medicine 2017 15:112

    Published on:

  16. Content type: Research

    The lack of early diagnosis, progression markers and effective pharmacological treatment has dramatic unfavourable effects on clinical outcomes in patients with peripheral artery disease (PAD). Addressing thes...

    Authors: Giorgio Aquila, Cinzia Fortini, Antonio Pannuti, Serena Delbue, Micaela Pannella, Marco Bruno Morelli, Cristiana Caliceti, Fausto Castriota, Monica de Mattei, Alessia Ongaro, Agnese Pellati, Pasquale Ferrante, Lucio Miele, Luigi Tavazzi, Roberto Ferrari, Paola Rizzo…

    Citation: Journal of Translational Medicine 2017 15:98

    Published on:

  17. Content type: Review

    A series of clinical trials have confirmed the correlation between vascular calcification (VC) and cardiovascular events and mortality. However, current treatments have little effects on the regression of VC. ...

    Authors: Adham Sameer A. Bardeesi, Jingwei Gao, Kun Zhang, Suntian Yu, Mengchao Wei, Pinming Liu and Hui Huang

    Citation: Journal of Translational Medicine 2017 15:95

    Published on:

  18. Content type: Research

    Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that ...

    Authors: Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy and Adriana Adameová

    Citation: Journal of Translational Medicine 2017 15:86

    Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:103

  19. Content type: Research

    Hypertrophic cardiomyopathy (HCM) patients with early repolarization (ER) pattern are at higher risk of ventricular arrhythmia, yet the genetic background of this situation has not been well investigated. Here...

    Authors: Yanhong Chen, Hector Barajas-Martinez, Dongxiao Zhu, Xihui Wang, Chonghao Chen, Ruijuan Zhuang, Jingjing Shi, Xueming Wu, Yijia Tao, Weidong Jin, Xiaoyan Wang and Dan Hu

    Citation: Journal of Translational Medicine 2017 15:78

    Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:101

  20. Content type: Research

    We aimed to determine the circulating miRNA expression profile associated with BAV and aortic dilation to provide diagnostic and prognostic biomarkers for BAV and/or aortic dilation.

    Authors: Neus Martínez-Micaelo, Raúl Beltrán-Debón, Isabel Baiges, Marta Faiges and Josep M. Alegret

    Citation: Journal of Translational Medicine 2017 15:76

    Published on:

Previous Page Page 1 of 8 Next Page

2016 Journal Metrics