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Cell, tissue and gene therapy

Section edited by David Stroncek

This section aims to improve communication between basic and clinical research related to cell, tissue and gene therapies. Effective clinical therapies require efficient translation of research between the bench and bedside to allow the discovery, development, scale up, and production of cells, tissues and vectors. These therapies are being used to treat patients with a range of diseases including cancer, cardiovascular diseases, autoimmune disorders.

Studies considered for publication include those regarding the nature of cells, tissues and vectors used in clinical therapies; methods to collect, isolate and modify cells; and novel reagents, equipment, and instruments used in production. The section also welcomes research into the application of clinical therapies; factors that effect the safety and efficacy; in particular the potency, stability and purity of cells or tissue; and issues related to the safety of cell and tissue donors.

Featured articles

A therapeutic cancer vaccine against GL261 murine glioma
Mark S. Kindy, et al



Endothelium-targeted human Delta-like 1 enhances the regeneration and homing of human cord blood stem and progenitor cells
Deng-Mei Tian, Ying-Min Liang and Yong-Qing Zhang


Obesity inhibits the osteogenic differentiation of human adipose-derived stem cells
Amy L. Strong, et al

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  1. Stored platelets undergo deleterious changes, referred to as platelet storage lesions (PSLs), which accelerate the desialylation of platelets and result in their phagocytosis and clearance by hepatic macrophag...

    Authors: Jooyoung Cho, Hyunkyung Kim, Jaewoo Song, June-Won Cheong, Jeong Won Shin, Woo Ick Yang and Hyun Ok Kim

    Citation: Journal of Translational Medicine 2018 16:199

    Content type: Research

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  2. Spinal cord injury (SCI) is one of the most severe central nervous system injuries. Currently, transplanting bone marrow mesenchymal stem cells (BMSCs) is considered a therapeutic option for SCI. Tanshinone II...

    Authors: Xue-Mei Zhang, Jiao Ma, Yang Sun, Bing-Qian Yu, Zhuo-Min Jiao, Duo Wang, Mei-Yu Yu, Jin-Yue Li and Jin Fu

    Citation: Journal of Translational Medicine 2018 16:193

    Content type: Research

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  3. To explore the mechanism of the different clinical efficacies of mesenchymal stem cell transplantation (MSCT) and identify a possible serum biomarker for predicting the therapeutic effect of MSCT in rheumatoid...

    Authors: Yi Yang, Xiao He, Rongseng Zhao, Wei Guo, Ming Zhu, Wei Xing, Dongpo Jiang, Chongyang Liu and Xiang Xu

    Citation: Journal of Translational Medicine 2018 16:165

    Content type: Research

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  4. The reconstruction of bone defects is often impaired by radiotherapy since bone quality is compromised by radiation. This study aims to investigate the therapeutic efficacy of the composite cell sheets-bone ma...

    Authors: Huan Liu, Yang Jiao, Wei Zhou, Shizhu Bai, Zhihong Feng, Yan Dong, Qian Liu, Xiaoke Feng and Yimin Zhao

    Citation: Journal of Translational Medicine 2018 16:137

    Content type: Research

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  5. Cell homing is the mechanism by which an injury releases signaling molecules that cause recruitment, proliferation, migration and differentiation of progenitor cells. Stromal derived factor-1 (SDF-1) and its r...

    Authors: Melissa Kristocheck, Lucinara D. Dias, Carine Ghem, Bruna Eibel, Renato A. K. Kalil and Melissa M. Markoski

    Citation: Journal of Translational Medicine 2018 16:133

    Content type: Research

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  6. Stem cell therapy has been applied in the treatment of acute-on-chronic liver failure (ACLF). However, its clinical efficiency is still debatable. The aim of this systematic review and meta-analysis is to eval...

    Authors: Ran Xue, Qinghua Meng, Jinling Dong, Juan Li, Qinwei Yao, Yueke Zhu and Hongwei Yu

    Citation: Journal of Translational Medicine 2018 16:126

    Content type: Research

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  7. A major complication after allogeneic hematopoietic stem cell transplantation (aSCT) is the reactivation of herpesviruses such as cytomegalovirus (CMV) and Epstein–Barr virus (EBV). Both viruses cause signific...

    Authors: Regina Gary, Michael Aigner, Stephanie Moi, Stefanie Schaffer, Anja Gottmann, Stefanie Maas, Robert Zimmermann, Jürgen Zingsem, Julian Strobel, Andreas Mackensen, Josef Mautner, Andreas Moosmann and Armin Gerbitz

    Citation: Journal of Translational Medicine 2018 16:124

    Content type: Methodology

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  8. The role of rabbit synovial fluid-derived mesenchymal stem cells (rbSF-MSCs) in cartilage defect repair remains undefined. This work evaluates the in vivo effects of rbSF-MSCs to repair knee articular cartilag...

    Authors: Zhaofeng Jia, Qisong Liu, Yujie Liang, Xingfu Li, Xiao Xu, Kan Ouyang, Jianyi Xiong, Daping Wang and Li Duan

    Citation: Journal of Translational Medicine 2018 16:123

    Content type: Research

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  9. Pancreatic ductal adenocarcinoma (PDAC) has been increasing by 0.5% per year in the United States. PDAC portends a dismal prognosis and novel therapies are needed. This study describes the generation and chara...

    Authors: Michael P. O’Leary, Audrey H. Choi, Sang-In Kim, Shyambabu Chaurasiya, Jianming Lu, Anthony K. Park, Yanghee Woo, Susanne G. Warner, Yuman Fong and Nanhai G. Chen

    Citation: Journal of Translational Medicine 2018 16:110

    Content type: Research

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  10. Saethre–Chotzen syndrome is an autosomal dominantly inherited disorder caused by mutations in the twist family basic helix-loop-helix transcription factor 1 (TWIST1) gene. Surgical procedures are frequently re...

    Authors: Shanshan Bai, Dong Li, Liang Xu, Huichuan Duan, Jie Yuan and Min Wei

    Citation: Journal of Translational Medicine 2018 16:103

    Content type: Research

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  11. Radiation-induced lung toxicity (RILT) is a severe complication of radiotherapy in patients with thoracic tumors. Through proteomics, we have previously identified vitronectin (VTN) as a potential biomarker fo...

    Authors: Tian-Le Shen, Mi-Na Liu, Qin Zhang, Wen Feng, Wen Yu, Xiao-Long Fu and Xu-Wei Cai

    Citation: Journal of Translational Medicine 2018 16:100

    Content type: Research

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  12. Members in Motin family, or Angiomotins (AMOTs), are adaptor proteins that localize in the membranous, cytoplasmic or nuclear fraction in a cell context-dependent manner. They control the bioprocesses such as ...

    Authors: Tingting Huang, Yuhang Zhou, Jinglin Zhang, Alfred S. L. Cheng, Jun Yu, Ka Fai To and Wei Kang

    Citation: Journal of Translational Medicine 2018 16:98

    Content type: Review

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  13. Bone marrow stromal cells (BMSCs) have classically been cultured in media supplemented with fetal bovine serum (FBS). As an alternative to FBS, pooled solvent detergent apheresis platelets, HPGF-C18, was evalu...

    Authors: Jiaqiang Ren, Dawn Ward, Steven Chen, Katherine Tran, Ping Jin, Marianna Sabatino, Pamela G. Robey and David F. Stroncek

    Citation: Journal of Translational Medicine 2018 16:65

    Content type: Research

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  14. Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly characterized by retinal pigment epithelium (RPE) degeneration with accumulation of abnormal intracellular deposits (lip...

    Authors: George Inana, Christopher Murat, Weijun An, Xiang Yao, Ian R. Harris and Jing Cao

    Citation: Journal of Translational Medicine 2018 16:63

    Content type: Research

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  15. Multiple sclerosis (MS) is a progressively debilitating neurological condition in which the immune system abnormally erodes the myelin sheath insulating the nerves. Mesenchymal stem cells (MSC) have been used ...

    Authors: Neil H. Riordan, Isabela Morales, Giselle Fernández, Nicole Allen, Neal E. Fearnot, Michael E. Leckrone, Dedra Jones Markovich, Darla Mansfield, Dorita Avila, Amit N. Patel, Santosh Kesari and Jorge Paz Rodriguez

    Citation: Journal of Translational Medicine 2018 16:57

    Content type: Research

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  16. Kidneys from deceased donors are being used to meet the growing need for grafts. However, delayed graft function (DGF) and acute rejection incidences are high, leading to adverse effects on graft outcomes. Opt...

    Authors: Qipeng Sun, Zhengyu Huang, Fei Han, Ming Zhao, Ronghua Cao, Daqiang Zhao, Liangqing Hong, Ning Na, Heng Li, Bin Miao, Jianmin Hu, Fanhang Meng, Yanwen Peng and Qiquan Sun

    Citation: Journal of Translational Medicine 2018 16:52

    Content type: Research

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  17. Cell therapies are being investigated as potential disease modifying treatment options for osteoarthritis (OA). Progenza (PRG) comprises in vitro expanded mesenchymal stem cells derived from human donor adipos...

    Authors: D. Kuah, S. Sivell, T. Longworth, K. James, A. Guermazi, F. Cicuttini, Y. Wang, S. Craig, G. Comin, D. Robinson and J. Wilson

    Citation: Journal of Translational Medicine 2018 16:49

    Content type: Research

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  18. The role of transforming growth factorβ (TGF-β)-induced tumor progression in advanced malignancy is well established, but the involvement of long non-coding RNAs (lncRNAs) in TGF-β signaling remains unclear. T...

    Authors: Teng Huang, Wei Huang, Hong Lu, Bi-yun Zhang, Jun Ma, Di Zhao, Yi-jun Wang, Da-hai Yu and Xia He

    Citation: Journal of Translational Medicine 2018 16:46

    Content type: Research

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  19. Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery. The ideal treatment for such tissue loss is autografting, but donor sites are often limited. Tissue engineering (TE)...

    Authors: Pan Wu, Haojiao Chen, Ronghua Jin, Tingting Weng, Jon Kee Ho, Chuangang You, Liping Zhang, Xingang Wang and Chunmao Han

    Citation: Journal of Translational Medicine 2018 16:29

    Content type: Review

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  20. We have recently shown that memory B cells from murine CMV immune donor animals adoptively transferred into immunodeficient mice were highly effective in protecting from a viral infection indicating a therapeu...

    Authors: Hannes Tittlbach, Andrea Schneider, Julian Strobel, Robert Zimmermann, Stefanie Maas, Bernd Gebhardt, Georg Rauser, Michael Mach, Andreas Mackensen, Thomas H. Winkler and Julia Winkler

    Citation: Journal of Translational Medicine 2017 15:228

    Content type: Methodology

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  21. Degenerative disc disease (DDD) is a common cause of lower back pain with radicular symptoms and has a significant socioeconomic impact given the associated disability. Limited effective conservative therapeut...

    Authors: Christopher Centeno, Jason Markle, Ehren Dodson, Ian Stemper, Christopher J. Williams, Matthew Hyzy, Thomas Ichim and Michael Freeman

    Citation: Journal of Translational Medicine 2017 15:197

    Content type: Research

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  22. Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a poss...

    Authors: Emanuela Cherubini, Salvatore Mariotta, Davide Scozzi, Rita Mancini, Giorgia Osman, Michela D’Ascanio, Pierdonato Bruno, Giuseppe Cardillo and Alberto Ricci

    Citation: Journal of Translational Medicine 2017 15:196

    Content type: Research

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  23. This review based on translational research predicts that the transcription factor p53 is the key effector of all anti-acne therapies. All-trans retinoic acid (ATRA) and isotretinoin (13-cis retinoic acid) enhanc...

    Authors: Bodo C. Melnik

    Citation: Journal of Translational Medicine 2017 15:195

    Content type: Review

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  24. Reduced levels of endothelial progenitor cells (EPCs) counts have been reported in diabetic mellitus (DM) patients and other diabetes-related disorder. EPCs are a circulating, bone marrow-derived cell populati...

    Authors: Rashmi K. Ambasta, Harleen Kohli and Pravir Kumar

    Citation: Journal of Translational Medicine 2017 15:185

    Content type: Review

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  25. In humans, the heterochronic cascade composed of the RNA-binding protein LIN28 and its major target, the let-7 family of microRNAs (miRNAs), is highly regulated during human erythroid ontogeny. Additionally, down...

    Authors: Jaira F. de Vasconcellos, Colleen Byrnes, Y. Terry Lee, Joshua M. Allwardt, Megha Kaushal, Antoinette Rabel and Jeffery L. Miller

    Citation: Journal of Translational Medicine 2017 15:169

    Content type: Research

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  26. Cardiovascular disease remains a major health care challenge. The knowledge about the underlying mechanisms of the respective vascular disease etiologies has greatly expanded over the last decades. This includ...

    Authors: Christoph S. Nabzdyk, Leena Pradhan-Nabzdyk and Frank W. LoGerfo

    Citation: Journal of Translational Medicine 2017 15:164

    Content type: Review

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  27. In an attempt to increase the therapeutic potential for myocardial regeneration, there is a quest for new cell sources and types for cell therapy protocols. The pathophysiology of heart diseases may affect cel...

    Authors: Lucinara Dadda Dias, Karina Rabello Casali, Carine Ghem, Melissa Kristocheck da Silva, Grasiele Sausen, Patrícia Bonini Palma, Dimas Tadeu Covas, Renato A. K. Kalil, Beatriz D. Schaan, Nance Beyer Nardi and Melissa Medeiros Markoski

    Citation: Journal of Translational Medicine 2017 15:161

    Content type: Research

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  28. Cell-based therapy is being explored as an alternative treatment option for critical limb ischemia (CLI), a disease associated with high amputation and mortality rates and poor quality of life. However, therap...

    Authors: Adas Darinskas, Mindaugas Paskevicius, Gintaras Apanavicius, Gintaris Vilkevicius, Liutauras Labanauskas, Thomas E. Ichim and Rytis Rimdeika

    Citation: Journal of Translational Medicine 2017 15:143

    Content type: Research

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  29. Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. We evaluated the safety and prelimi...

    Authors: Himanshu Bansal, Kristin Comella, Jerry Leon, Poonam Verma, Diwaker Agrawal, Prasad Koka and Thomas Ichim

    Citation: Journal of Translational Medicine 2017 15:141

    Content type: Research

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  30. Children with congenital heart defects (CHDs) are at high risk for myocardial failure after operative procedures with cardiopulmonary bypass (CPB). Recent studies suggest that microRNAs (miRNA) are involved in...

    Authors: Masood Abu-Halima, Martin Poryo, Nicole Ludwig, Janine Mark, Ina Marsollek, Christian Giebels, Johannes Petersen, Hans-Joachim Schäfers, Ulrich Grundmann, Thomas Pickardt, Andreas Keller, Eckart Meese and Hashim Abdul-Khaliq

    Citation: Journal of Translational Medicine 2017 15:117

    Content type: Research

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  31. Numerous studies have investigated the role of the dietary factors in the prevention of cognitive decline but the short-term effects of foods choice on cognitive performances in the elderly are poorly explored...

    Authors: Elisa Mazza, Antonietta Fava, Yvelise Ferro, Marta Moraca, Stefania Rotundo, Carmela Colica, Francesco Provenzano, Rosa Terracciano, Marta Greco, Daniela Foti, Elio Gulletta, Diego Russo, Domenico Bosco, Arturo Pujia and Tiziana Montalcini

    Citation: Journal of Translational Medicine 2017 15:109

    Content type: Research

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  32. Retinal degeneration (RD), such as age-related macular degeneration (AMD) and retinitis pigmentosa, is one of the leading causes of blindness. Presently, no satisfactory therapeutic options are available for t...

    Authors: Zhimin Tang, Yi Zhang, Yuyao Wang, Dandan Zhang, Bingqiao Shen, Min Luo and Ping Gu

    Citation: Journal of Translational Medicine 2017 15:99

    Content type: Review

    Published on:

  33. Adeno-associated virus (AAV) gene therapy vectors have shown the best outcomes in human clinical studies for the treatment of genetic diseases such as hemophilia. However, these pivotal investigations have als...

    Authors: David M. Markusic, Timothy C. Nichols, Elizabeth P. Merricks, Brett Palaschak, Irene Zolotukhin, Damien Marsic, Sergei Zolotukhin, Arun Srivastava and Roland W. Herzog

    Citation: Journal of Translational Medicine 2017 15:94

    Content type: Research

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  34. The use of fetal bovine serum (FBS) as a media supplement for the ex vivo expansion of bone-marrow derived mesenchymal stromal cells (BM-MSC) has been discouraged by regulatory agencies, due to the risk of tra...

    Authors: Martina Bernardi, Francesco Agostini, Katia Chieregato, Eliana Amati, Cristina Durante, Mario Rassu, Marco Ruggeri, Sabrina Sella, Elisabetta Lombardi, Mario Mazzucato and Giuseppe Astori

    Citation: Journal of Translational Medicine 2017 15:90

    Content type: Research

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  35. Hepatocellular carcinoma (HCC) is one of the most common cancers in China and frequently occurs with chronic hepatitis B virus infection. To investigate whether cell-based cancer immunotherapy induces tumor sp...

    Authors: Yanyan Han, Yeting Wu, Chou Yang, Jing Huang, Yabing Guo, Li Liu, Ping Chen, Dongyun Wu, Junyun Liu, Jin Li, Xiangjun Zhou and Jinlin Hou

    Citation: Journal of Translational Medicine 2017 15:64

    Content type: Research

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  36. Clinical trials of Chimeric Antigen Receptor (CAR) T cells manufactured from autologous peripheral blood mononuclear cell (PBMC) concentrates for the treatment of hematologic malignancies have been promising, ...

    Authors: David F. Stroncek, Daniel W. Lee, Jiaqiang Ren, Marianna Sabatino, Steven Highfill, Hanh Khuu, Nirali N. Shah, Rosandra N. Kaplan, Terry J. Fry and Crystal L. Mackall

    Citation: Journal of Translational Medicine 2017 15:59

    Content type: Research

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  37. Critical limb ischemia (CLI) causes severe ischemic rest pain, ulcer, and gangrene in the lower limbs. In spite of angioplasty and surgery, CLI patients without suitable artery inflow or enough vascular bed in...

    Authors: Makoto Samura, Tohru Hosoyama, Yuriko Takeuchi, Koji Ueno, Noriyasu Morikage and Kimikazu Hamano

    Citation: Journal of Translational Medicine 2017 15:49

    Content type: Review

    Published on:

  38. Bone marrow mesenchymal stem cells (BMMSCs) and bone marrow mononuclear cells (BMMNCs) are both used to treat spastic cerebral palsy. However, the differences in therapeutic effect remain unknown.

    Authors: Xuebin Liu, Xiaojun Fu, Guanghui Dai, Xiaodong Wang, Zan Zhang, Hongbin Cheng, Pei Zheng and Yihua An

    Citation: Journal of Translational Medicine 2017 15:48

    Content type: Research

    Published on:

  39. Sarcopenia, osteoporosis and osteoarthritis are the most frequent musculoskeletal disorders affecting older people. The main aim of this study was to test the hypothesis that the balance between BMPs and myost...

    Authors: Manuel Scimeca, Eleonora Piccirilli, Francesca Mastrangeli, Cecilia Rao, Maurizio Feola, Augusto Orlandi, Elena Gasbarra, Elena Bonanno and Umberto Tarantino

    Citation: Journal of Translational Medicine 2017 15:34

    Content type: Research

    Published on:

  40. Mesenchymal stem cell (MSC) has been widely explored in the past decade as a cell-based treatment for various diseases. However, poor survival of adaptively transferred MSCs limits their clinical therapeutic p...

    Authors: Shuo Wang, Chao Zhang, Sidikejiang Niyazi, Long Zheng, Jiawei Li, Weitao Zhang, Ming Xu, Ruiming Rong, Cheng Yang and Tongyu Zhu

    Citation: Journal of Translational Medicine 2017 15:33

    Content type: Research

    Published on:

  41. We performed a randomized, double-blind, cross-over study to assess the neuroregenerative potential of intravenous granulocyte colony-stimulating factor (G-CSF) followed by infusion of mobilized peripheral blo...

    Authors: Wee-Jin Rah, Young-Ho Lee, Jin-Hwa Moon, Hyun-Ju Jun, Hye-Ryeong Kang, Hani Koh, Hye Jung Eom, Ji Young Lee, Young Jun Lee, Ji Young Kim, Yun-Young Choi, Kyeongil Park, Mi Jung Kim and Seung-Hyun Kim

    Citation: Journal of Translational Medicine 2017 15:16

    Content type: Research

    Published on:

  42. Stromal vascular fraction (SVF) can easily be obtained from a mini-lipoaspirate procedure of fat tissue and platelet rich plasma (PRP) can be obtained from peripheral blood. The SVF contains a mixture of cells...

    Authors: Kristin Comella, Robert Silbert and Michelle Parlo

    Citation: Journal of Translational Medicine 2017 15:12

    Content type: Research

    Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:108

  43. The repair of urinary bladder tissue is a necessity for tissue loss due to cancer, trauma, or congenital abnormalities. Use of intestinal tissue is still the gold standard in the urological clinic, which leads...

    Authors: Dorothea Leonhäuser, Katja Stollenwerk, Volker Seifarth, Isabella M. Zraik, Michael Vogt, Pramod K. Srinivasan, Rene H. Tolba and Joachim O. Grosse

    Citation: Journal of Translational Medicine 2017 15:3

    Content type: Research

    Published on:

  44. Induced pluripotent stem cells (iPSC) possess an enormous potential as both, scientific and therapeutic tools. Their application in the regenerative medicine provides new treatment opportunities for numerous d...

    Authors: Maciej P. Walczak, Anna M. Drozd, Ewelina Stoczynska-Fidelus, Piotr Rieske and Dawid P. Grzela

    Citation: Journal of Translational Medicine 2016 14:341

    Content type: Research

    Published on:

  45. Recent studies suggest that immunotherapy using T regulatory cells (Tregs) prolongs remission in type 1 diabetes (T1DM). Here, we report factors that possibly affect the efficacy of this treatment.

    Authors: Natalia Marek-Trzonkowska, Małgorzata Myśliwiec, Dorota Iwaszkiewicz-Grześ, Mateusz Gliwiński, Ilona Derkowska, Magdalena Żalińska, Maciej Zieliński, Marcelina Grabowska, Hanna Zielińska, Karolina Piekarska, Anna Jaźwińska-Curyłło, Radosław Owczuk, Agnieszka Szadkowska, Krystyna Wyka, Piotr Witkowski, Wojciech Młynarski…

    Citation: Journal of Translational Medicine 2016 14:332

    Content type: Research

    Published on:

  46. Myocardial recovery with left ventricular assist device (LVAD) therapy is highly variable and difficult to predict. Next generation ribonucleic acid (RNA) sequencing is an innovative, rapid, and quantitative a...

    Authors: Kajari Dhar, Alexandra M. Moulton, Eric Rome, Fang Qiu, Jeff Kittrell, Eugenia Raichlin, Ronald Zolty, John Y. Um, Michael J. Moulton, Hesham Basma, Daniel R. Anderson, James D. Eudy and Brian D. Lowes

    Citation: Journal of Translational Medicine 2016 14:327

    Content type: Research

    Published on:

  47. Adipose derived stromal cells (ASCs) are a rich and convenient source of cells for clinical regenerative therapeutic approaches. However, applications of ASCs often require cell expansion to reach the needed d...

    Authors: Mandana Haack-Sørensen, Bjarke Follin, Morten Juhl, Sonja K. Brorsen, Rebekka H. Søndergaard, Jens Kastrup and Annette Ekblond

    Citation: Journal of Translational Medicine 2016 14:319

    Content type: Research

    Published on:

  48. Cell-based therapies such as autologous chondrocyte implantation are promising therapeutic approaches to treat cartilage defects to prevent further cartilage degeneration. To assure consistent quality of cell-...

    Authors: Christoph Bartz, Miriam Meixner, Petra Giesemann, Giulietta Roël, Grit-Carsta Bulwin and Jeske J. Smink

    Citation: Journal of Translational Medicine 2016 14:317

    Content type: Research

    Published on:

  49. The endometrial regenerative cell (ERC) is a novel type of adult mesenchymal stem cell isolated from menstrual blood. Previous studies demonstrated that ERCs possess unique immunoregulatory properties in vitro...

    Authors: Shanzheng Lu, Ganggang Shi, Xiaoxi Xu, Grace Wang, Xu Lan, Peng Sun, Xiang Li, Baoren Zhang, Xiangying Gu, Thomas E. Ichim and Hao Wang

    Citation: Journal of Translational Medicine 2016 14:300

    Content type: Research

    Published on:

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