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Nutrition & metabolism

Section edited by Laura Soldati

This section aims to provide a platform for the interaction and mutual validation between basic and applied research in the field of nutrition. In the area of Translational Medicine, we believe that the field ought to be taken into greater account in order to generate advanced applications for diagnosis and therapy and, at the same time, to develop new instruments of investigation.

Studies on all aspects of nutrition and metabolism with applications in medicine and biotechnology will be considered for publication. The section not only welcomes contributions that employ traditional clinical, metabolic and epidemiologic methods, but is also interested in molecular and cell biology applied to human and animal nutrition.

Featured articles

Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade
Hsing-Chun Kuo, et al

Obesity and colorectal cancer: molecular features of adipose tissue
Javier Martinez-Useros and Jesus Garcia-Foncillas

Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation
Tri Vuong, et al

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  1. Content type: Review

    Advanced studies of microRNAs (miRNAs) have revealed their manifold biological functions, including control of cell proliferation, cell cycle and cell death. However, it seems that their roles as key regulator...

    Authors: Bing Chen, Hongbin Li, Xiao Zeng, Pengbo Yang, Xinyu Liu, Xia Zhao and Shufang Liang

    Citation: Journal of Translational Medicine 2012 10:228

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  2. Content type: Research

    Epithelial-mesenchymal transition of tubular cells is a widely recognized mechanism that sustains interstitial fibrosis in diabetic nephropathy (DN). The signaling of FGF-2, a growth factor involved in this me...

    Authors: Valentina Masola, Maurizio Onisto, Gianluigi Zaza, Antonio Lupo and Giovanni Gambaro

    Citation: Journal of Translational Medicine 2012 10:213

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  3. Content type: Research

    Nonylphenol (NP), an environmental organic compound, has been demonstrated to enhance reactive-oxygen species (ROS) synthesis. Chronic exposure to low-dose adenine (AD) has been reported to induce chronic kidn...

    Authors: Chia-Hung Yen, Cheuk-Kwan Sun, Steve Leu, Christopher Glenn Wallace, Yu-Chun Lin, Li-Teh Chang, Yung-Lung Chen, Tzu-Hsien Tsa, Ying-Hsien Kao, Pei-Lin Shao, Chi-Ying Hsieh, Yen-Ta Chen and Hon-Kan Yip

    Citation: Journal of Translational Medicine 2012 10:147

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  4. Content type: Research

    Obesity is an important cardiovascular risk factor. This study tested the effect of obesity reduction on preserving left ventricular ejection fraction (LVEF) and attenuating inflammation, oxidative stress and ...

    Authors: Hui-Ting Wang, Chu-Feng Liu, Tzu-Hsien Tsai, Yung-Lung Chen, Hsueh-Wen Chang, Ching-Yen Tsai, Steve Leu, Yen-Yi Zhen, Han-Tan Chai, Sheng-Ying Chung, Sarah Chua, Chia-Hung Yen and Hon-Kan Yip

    Citation: Journal of Translational Medicine 2012 10:145

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  5. Content type: Research

    Low birth weight has been linked to an increased risk to develop obesity, type 2 diabetes, and hypertension in adult life, although the mechanisms underlying the association are not well understood. The object...

    Authors: Carmen Ivorra, Consuelo García-Vicent, Felipe Javier Chaves, Daniel Monleón, José Manuel Morales and Empar Lurbe

    Citation: Journal of Translational Medicine 2012 10:142

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  6. Content type: Research

    This study tested the hypothesis that obesity suppresses circulating number as well as the function of endothelial progenitor cells (EPCs) and left ventricular ejection fraction (LVEF).

    Authors: Tzu-Hsien Tsai, Han-Tan Chai, Cheuk-Kwan Sun, Chia-Hung Yen, Steve Leu, Yung-Lung Chen, Sheng-Ying Chung, Sheung-Fat Ko, Hsueh-Wen Chang, Chiung-Jen Wu and Hon-Kan Yip

    Citation: Journal of Translational Medicine 2012 10:137

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  7. Content type: Research

    Experimental studies suggested that high serum calcium may be important in the pathogenesis of vascular diseases. Since calcium seems to affect specifically the cerebrovascular district, aim of this study was ...

    Authors: Tiziana Montalcini, Gaetano Gorgone and Arturo Pujia

    Citation: Journal of Translational Medicine 2012 10:114

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  8. Content type: Research

    Nutrition has been widely recognized to influence the risk of kidney stone formation. Therefore the aim of our study was to assess: a) whether usual diet of women with idiopathic calcium nephrolithiasis (ICN) ...

    Authors: Tiziana Meschi, Antonio Nouvenne, Andrea Ticinesi, Beatrice Prati, Angela Guerra, Franca Allegri, Federica Pigna, Laura Soldati, Giuseppe Vezzoli, Giovanni Gambaro, Fulvio Lauretani, Marcello Maggio and Loris Borghi

    Citation: Journal of Translational Medicine 2012 10:63

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