Medical bioinformatics

Section edited by Samir K. Brahmachari

The explosion of genome sequencing data along with genotype to phenotype correlation studies has created data deluge in the area of biomedical sciences. The aim of the Medical bioinformatics section is to aid the development and maturation of the field by providing a platform for the translation of these datasets into useful clinical applications. The increase in computing capabilities and availability of different data from advanced technologies will allow researchers to build System Biology models of various diseases in order to efficiently develop new therapeutic interventions and reduce the current prohibitively large costs of drug discovery.

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  1. Methodology

    Implementation of the CDC translational informatics platform - from genetic variants to the national Swedish Rheumatology Quality Register

    Sequencing of the human genome and the subsequent analyses have produced immense volumes of data. The technological advances have opened new windows into genomics beyond the DNA sequence. In parallel, clinical...

    Imad Abugessaisa, David Gomez-Cabrero, Omri Snir, Staffan Lindblad, Lars Klareskog, Vivianne Malmström and Jesper Tegnér

    Journal of Translational Medicine 2013 11:85

    Published on: 2 April 2013

  2. Research

    In silico approaches for designing highly effective cell penetrating peptides

    Cell penetrating peptides have gained much recognition as a versatile transport vehicle for the intracellular delivery of wide range of cargoes (i.e. oligonucelotides, small molecules, proteins, etc.), that other...

    Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Arun Sharma, Pallavi Kapoor, Atul Tyagi and Gajendra P S Raghava

    Journal of Translational Medicine 2013 11:74

    Published on: 22 March 2013

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