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Cell, Tissue and Gene Therapy

Section edited by David Stroncek

This section aims to improve communication between basic and clinical research related to cell, tissue and gene therapies. Effective clinical therapies require efficient translation of research between the bench and bedside to allow the discovery, development, scale up, and production of cells, tissues and vectors. These therapies are being used to treat patients with a range of diseases including cancer, cardiovascular diseases, autoimmune disorders.

Studies considered for publication include those regarding the nature of cells, tissues and vectors used in clinical therapies; methods to collect, isolate and modify cells; and novel reagents, equipment, and instruments used in production. The section also welcomes research into the application of clinical therapies; factors that effect the safety and efficacy; in particular the potency, stability and purity of cells or tissue; and issues related to the safety of cell and tissue donors.

Featured articles

Phase I and registry study of autologous bone marrow concentrate evaluated in PDE5 inhibitor refractory erectile dysfunction

Research | Mark Bieri et al


Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients​​​​​​​

Review | Christopher J. Rogers et al


Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreak

Review |  Michael Har-Noy & Reuven Or 

Page 9 of 11

  1. The naked caspase-3 small interfering RNA (siRNA) infused into the renal artery during cold preservation was effective, but did not protect auto-transplant porcine kidneys with increased inflammation and apopt...

    Authors: Cheng Yang, Long Li, Yinjia Xue, Zitong Zhao, Tian Zhao, Yichen Jia, Ruiming Rong, Ming Xu, Michael L Nicholson, Tongyu Zhu and Bin Yang
    Citation: Journal of Translational Medicine 2013 11:210
    Content type: Research Published on:

  2. Ulcerative colitis (UC) is the most common form of inflammatory bowel disease in the USA. A key component of UC is the increase in inflammatory angiogenesis of the colon during active disease. This increase is...

    Authors: Walter E Cromer, Chaitanya V Ganta, Mihir Patel, James Traylor, Christopher G Kevil, J Steven Alexander and J Michael Mathis
    Citation: Journal of Translational Medicine 2013 11:207
    Content type: Research Published on:

  3. Longikaurin A is a natural ent-kaurene diterpenoid isolated from Isodon genus. The ent-kaurene diterpenoids isolated from medicinal plants have been shown to have anti-disease effects. The present study was desig...

    Authors: Qing-Feng Zou, Ji-Ke Du, Hua Zhang, Hong-Bo Wang, Ze-Dong Hu, Shu-Peng Chen, Yong Du, Man-Zhi Li, Dan Xie, Juan Zou, Han-Dong Sun, Jian-Xin Pu and Mu-Sheng Zeng
    Citation: Journal of Translational Medicine 2013 11:200
    Content type: Research Published on:

  4. The quality and safety of cell therapy products must be maintained throughout their production and quality control cycle, ensuring their final use in the patient. We validated the Lymulus Amebocyte Lysate (LAL...

    Authors: Deborah Rustichelli, Sara Castiglia, Monica Gunetti, Katia Mareschi, Elena Signorino, Michela Muraro, Laura Castello, Fiorella Sanavio, Marco Leone, Ivana Ferrero and Franca Fagioli
    Citation: Journal of Translational Medicine 2013 11:197
    Content type: Methodology Published on:

  5. Autism is a pervasive neurodevelopmental disorder. At present there are no defined mechanisms of pathogenesis and therapy is mostly limited to behavioral interventions. Stem cell transplantation may offer a un...

    Authors: Yong-Tao Lv, Yun Zhang, Min Liu, Jia-na-ti Qiuwaxi, Paul Ashwood, Sungho Charles Cho, Ying Huan, Ru-Cun Ge, Xing-Wang Chen, Zhao-Jing Wang, Byung-Jo Kim and Xiang Hu
    Citation: Journal of Translational Medicine 2013 11:196
    Content type: Research Published on:

  6. Oncolytic viruses have shown potential as cancer therapeutics, but not all patients seem to benefit from therapy. Polymorphisms in Fc gamma receptors (FcgRs) lead to altered binding affinity of IgG between the...

    Authors: Mari Hirvinen, Raita Heiskanen, Minna Oksanen, Saila Pesonen, Ilkka Liikanen, Timo Joensuu, Anna Kanerva, Vincenzo Cerullo and Akseli Hemminki
    Citation: Journal of Translational Medicine 2013 11:193
    Content type: Research Published on:

  7. The current study sought to investigate the safety of intraoperative and early postoperative continuous hyperthermic intraperitoneal perfusion (IEPCHIP) at different temperatures in a swine model of experiment...

    Authors: Sheng Li, Yong-lei Zhang, Jia-yuan Sun, Ya-wei Hua and Pei-hong Wu
    Citation: Journal of Translational Medicine 2013 11:181
    Content type: Research Published on:

  8. Adipose-derived stromal cells (ADSCs) are a good alternative to multipotent stem cells for regenerative medicine. Low tidal volume (LVT) has proved to be an effective ventilation strategy. However, it is not k...

    Authors: Zuo Di Liang, Xiu Ru Yin, Da Sheng Cai, Heng Zhou and Ling Pei
    Citation: Journal of Translational Medicine 2013 11:179
    Content type: Research Published on:

  9. Mesenchymal stem cells (MSCs) are known to be capable of suppressing inflammatory responses. We previously reported that intra-abdominal implantation of bone marrow-derived MSCs (BM-MSCs) sheet by laparotomy a...

    Authors: Xian-ming Fu, Aika Yamawaki-Ogata, Hideki Oshima, Yuichi Ueda, Akihiko Usui and Yuji Narita
    Citation: Journal of Translational Medicine 2013 11:175
    Content type: Research Published on:

  10. Regenerative medicine and particular adult stem cells represent an alternative option with several fruitful therapeutic applications in patients suffering from chronic lung diseases including idiopathic pulmon...

    Authors: Argyris Tzouvelekis, Vassilis Paspaliaris, George Koliakos, Paschalis Ntolios, Evangelos Bouros, Anastasia Oikonomou, Athanassios Zissimopoulos, Nikolaos Boussios, Brian Dardzinski, Dimitrios Gritzalis, Antonis Antoniadis, Marios Froudarakis, George Kolios and Demosthenes Bouros
    Citation: Journal of Translational Medicine 2013 11:171
    Content type: Research Published on:

  11. Glioblastoma multiforme (GBM) is one of the most aggressive forms of cancer with a high rate of recurrence. We propose a novel oncolytic vaccinia virus (VACV)-based therapy using expression of the bone morphog...

    Authors: Rohit Duggal, Ulrike Geissinger, Qian Zhang, Jason Aguilar, Nanhai G Chen, Elena Binda, Angelo L Vescovi and Aladar A Szalay
    Citation: Journal of Translational Medicine 2013 11:155
    Content type: Research Published on:

  12. Colorectal cancer (CRC) remains one of the most common cancers worldwide. We observed that MUC20 was significantly up-regulated in CRC patients with poor prognosis based on the microarray analysis. However, li...

    Authors: Xiuying Xiao, Lisha Wang, Ping Wei, Yayun Chi, Dali Li, Qifeng Wang, Shujuan Ni, Cong Tan, Weiqi Sheng, Menghong Sun, Xiaoyan Zhou and Xiang Du
    Citation: Journal of Translational Medicine 2013 11:151
    Content type: Research Published on:

  13. Peripheral vascular disease of the lower extremities comprises a clinical spectrum that extends from no symptoms to presentation with critical limb ischemia (CLI). Bone marrow derived Mesenchymal Stem Cells (B...

    Authors: Pawan K Gupta, Anoop Chullikana, Rajiv Parakh, Sanjay Desai, Anjan Das, Sanjay Gottipamula, Sagar Krishnamurthy, Naveen Anthony, Arun Pherwani and Anish S Majumdar
    Citation: Journal of Translational Medicine 2013 11:143
    Content type: Research Published on:

  14. The α2-adrenoreceptor agonist dexmedetomidine is known to provide renoprotection against ischemia and reperfusion (I/R) injury. However the underlying molecular mechanisms remain unclear. The purpose of this stud...

    Authors: Yanna Si, Hongguang Bao, Liu Han, Hongwei Shi, Yuan Zhang, Li Xu, Chenhui Liu, Jinsong Wang, Xiaobing Yang, Akbar Vohra and Daqing Ma
    Citation: Journal of Translational Medicine 2013 11:141
    Content type: Research Published on:

  15. While PDE5 inhibitors have revolutionized treatment of ED, approximately 30% of patients are non-responsive. A significant cause of this is vascular and smooth muscle dysfunction, as well as nerve atrophy. Aut...

    Authors: Thomas E Ichim, Timothy Warbington, Octav Cristea, Joseph L Chin and Amit N Patel
    Citation: Journal of Translational Medicine 2013 11:139
    Content type: Review Published on:

  16. Modified cell-based angiogenic therapy has become a promising novel strategy for ischemic heart and limb diseases. Most studies focused on myoblast, endothelial cell progenitors or bone marrow mesenchymal stro...

    Authors: Evgeny K Shevchenko, Pavel I Makarevich, Zoya I Tsokolaeva, Maria A Boldyreva, Veronika Yu Sysoeva, Vsevolod A Tkachuk and Yelena V Parfyonova
    Citation: Journal of Translational Medicine 2013 11:138
    Content type: Research Published on:

  17. In an attempt to engineer a regulatory compliant form of cell assisted lipotransfer in the U.S., the authors developed Autologous Fat Transfer with In-situ Mediation (AIM) for reconstruction of a refractory surgi...

    Authors: Allan Y Wu and David M Morrow
    Citation: Journal of Translational Medicine 2013 11:136
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2014 12:269

  18. Endothelial progenitor cells (EPCs) contribute to tumor angiogenesis and growth. We previously reported that over-expression of an inhibitor of DNA binding/differentiation 1 (Id1) in EPCs can enhance EPC proli...

    Authors: Yajuan Su, Lingjuan Gao, Lichen Teng, Ying Wang, Jialin Cui, Shiyun Peng and Songbin Fu
    Citation: Journal of Translational Medicine 2013 11:132
    Content type: Research Published on:

  19. Interactions between dendritic cells (DCs) and T cells play a critical role in the development of glomerulonephritis, which is a common cause of chronic kidney disease. DC-specific intercellular adhesion molec...

    Authors: Minchao Cai, Jing Wu, Chaoming Mao, Jianmin Ren, Pu Li, Xiao Li, Jiuchang Zhong, Chundi Xu and Tong Zhou
    Citation: Journal of Translational Medicine 2013 11:103
    Content type: Research Published on:

  20. Hepatopulmonary syndrome (HPS) is characterized by advanced liver disease, hypoxemia and intrapulmonary vascular dilatation (IPVD). The pathogenesis of HPS is not completely understood. Recent findings have es...

    Authors: Bin Yi, Jing Zeng, Guansong Wang, Guisheng Qian and Kaizhi Lu
    Citation: Journal of Translational Medicine 2013 11:98
    Content type: Research Published on:

  21. Mesenchymal stem cells (MSCs) are multi-potent non-hematopoietic progenitor cells possessing an immune-regulatory function, with suppression of proliferation of activated lymphocytes. In this study, adult livi...

    Authors: Hyunah Lee, Jae Berm Park, Sanghoon Lee, Soyoung Baek, HyunSoo Kim and Sung Joo Kim
    Citation: Journal of Translational Medicine 2013 11:96
    Content type: Research Published on:

  22. Celiac disease (CD) is mainly characterised by villous atrophy and mucosal architectural rearrangement. The fibroblasts (FBs) are the most abundant mesenchymal cell type in the intestinal mucosa and are respon...

    Authors: Leda Roncoroni, Luca Elli, Maria Teresa Bardella, Gianluca Perrucci, Michele Ciulla, Vincenza Lombardo, Carolina Tomba, Dario Conte and Luisa Doneda
    Citation: Journal of Translational Medicine 2013 11:91
    Content type: Research Published on:

  23. The use of adenoviral vector for gene therapy is still an important strategy for advanced cancers, however, the lack of the requisite coxsackie-adenovirus receptor in cancer cells and host immune response to a...

    Authors: Hua-shan Shi, Li-ping Yang, Wei Wei, Xiao-qing Su, Xiao-peng Li, Meng Li, Shun-tao Luo, Hai-long Zhang, Lian Lu, Yong-qiu Mao, Bing Kan and Li Yang
    Citation: Journal of Translational Medicine 2013 11:86
    Content type: Research Published on:

  24. Angiogenesis is a critical part of the endogenous repair process in brain injury and disease, and requires at least two sequential steps. First, angiogenic sprouting of endothelial cells occurs, which entails ...

    Authors: Mo Dao, Ciara C Tate, Michael McGrogan and Casey C Case
    Citation: Journal of Translational Medicine 2013 11:81
    Content type: Research Published on:

  25. Mesenchymal stem cell (MSC) transplantation has emerged as a promising therapy for liver fibrosis. Issues concerning poor MSC survival and engraftment in the fibrotic liver still persist and warrant developmen...

    Authors: Ghazanfar Ali Nasir, Sadia Mohsin, Mohsin Khan, Sulaiman Shams, Gibran Ali, Shaheen N Khan and Sheikh Riazuddin
    Citation: Journal of Translational Medicine 2013 11:78
    Content type: Research Published on:

  26. Heart failure is one of the key causes of morbidity and mortality world-wide. The recent findings that regeneration is possible in the heart have made stem cell therapeutics the Holy Grail of modern cardiovasc...

    Authors: Leo Bockeria, Vladimir Bogin, Olga Bockeria, Tatyana Le, Bagrat Alekyan, Erik J Woods, Amalia A Brown, Thomas E Ichim and Amit N Patel
    Citation: Journal of Translational Medicine 2013 11:56
    Content type: Review Published on:

  27. Age-related macular degeneration (AMD) is the leading cause of blindness in people over age 55 in the U.S. and the developed world. This condition leads to the progressive impairment of central visual acuity. ...

    Authors: Heather Melville, Matthew Carpiniello, Kia Hollis, Andrew Staffaroni and Nady Golestaneh
    Citation: Journal of Translational Medicine 2013 11:53
    Content type: Review Published on:

  28. Experimental clinical stem cell therapy has been used for more than a decade to alleviate the adverse aftermath of acute myocardial infarction (aMI). The post-infarcted myocardial microenvironment is character...

    Authors: Ewa Przybyt, Guido Krenning, Marja GL Brinker and Martin C Harmsen
    Citation: Journal of Translational Medicine 2013 11:39
    Content type: Research Published on:

  29. The early peritoneal invasion of epithelial ovarian cancer (EOC) by tumoral aggregates presents in ascites is a major concern. The role of the microenvironment seems to be important in this process but the lac...

    Authors: Cyril Touboul, Raphael Lis, Halema Al Farsi, Christophe M Raynaud, Mohamed Warfa, Hamda Althawadi, Eliane Mery, Massoud Mirshahi and Arash Rafii
    Citation: Journal of Translational Medicine 2013 11:28
    Content type: Research Published on:

  30. The discovery of mesenchymal stem cells (MSCs) or MSC-like cells in cartilage tissue does not tie in well with the established view that MSCs derive from a perivascular niche. The presence of MSCs may raise co...

    Authors: Karin Benz, Claudia Stippich, Christian Freudigmann, Juergen A Mollenhauer and Wilhelm K Aicher
    Citation: Journal of Translational Medicine 2013 11:27
    Content type: Research Published on:

  31. Linker for activation of T cells (LAT), a transmembrane adaptor protein, plays a role in T cell and mast cell function, while it remains unclear how histone modifications mediate LAT expression in allergic ast...

    Authors: Cheng-ye Li, Juan Peng, Lian-pin Ren, Li-xing Gan, Xiao-jiong Lu, Qian Liu, Wen Gu and Xue-jun Guo
    Citation: Journal of Translational Medicine 2013 11:26
    Content type: Research Published on:

  32. Kidneys derived from brain dead donors have lower graft survival and higher graft-function loss compared to their living donor counterpart. Heat Shock Proteins (HSP) are a large family of stress proteins invol...

    Authors: Leon FA van Dullemen, Eelke M Bos, Theo A Schuurs, Harm H Kampinga, Rutger J Ploeg, Harry van Goor and Henri GD Leuvenink
    Citation: Journal of Translational Medicine 2013 11:22
    Content type: Research Published on:

  33. Stem cell therapy is a promising treatment for cerebral palsy, which refers to a category of brain diseases that are associated with chronic motor disability in children. Autologous MSCs may be a better cell s...

    Authors: Guojun Chen, Yali Wang, Zhenyu Xu, Feng Fang, Renmei Xu, Yue Wang, Xiaoli Hu, Lixing Fan and Houqi Liu
    Citation: Journal of Translational Medicine 2013 11:21
    Content type: Research Published on:

  34. Mesenchymal stem cells (MSC) can serve as carriers to deliver oncolytic measles virus (MV) to ovarian tumors. In preparation for a clinical trial to use MSC as MV carriers, we obtained cells from ovarian cance...

    Authors: Emily K Mader, Greg Butler, Sean C Dowdy, Andrea Mariani, Keith L Knutson, Mark J Federspiel, Stephen J Russell, Evanthia Galanis, Allan B Dietz and Kah-Whye Peng
    Citation: Journal of Translational Medicine 2013 11:20
    Content type: Research Published on:

  35. ECBio has developed proprietary technology to consistently isolate, expand and cryopreserve a well-characterized population of stromal cells from human umbilical cord tissue (UCX® cells). The technology has re...

    Authors: Jorge M Santos, Rita N Bárcia, Sandra I Simões, Manuela M Gaspar, Susana Calado, Ana Água-Doce, Sílvia CP Almeida, Joana Almeida, Mariana Filipe, Mariana Teixeira, José P Martins, Luís Graça, Maria EM Cruz, Pedro Cruz and Helder Cruz
    Citation: Journal of Translational Medicine 2013 11:18
    Content type: Research Published on:

  36. Pharmacologic reactivation of fetal hemoglobin expression is a promising strategy for treatment of sickle cell disease and β-thalassemia. The objective of this study was to investigate the effect of the methyl...

    Authors: Yinghong He, Gerhard Rank, Miaomiao Zhang, Junyi Ju, Ronghua Liu, Zhen Xu, Fiona Brown, Loretta Cerruti, Chi Ma, Renxiang Tan, Stephen M Jane and Quan Zhao
    Citation: Journal of Translational Medicine 2013 11:14
    Content type: Research Published on:

  37. Interferon-γ (IFN-γ) is regarded as a potent antitumor agent, but its clinical application is limited by its short half-life and significant side effects. In this paper, we tried to develop IFN-γ gene therapy ...

    Authors: Ran-yi Liu, Ying-hui Zhu, Ling Zhou, Peng Zhao, Hong-li Li, Lan-cai Zhu, Hong-yu Han, Huan-xin Lin, Liang Kang, Jiang-xue Wu and Wenlin Huang
    Citation: Journal of Translational Medicine 2012 10:256
    Content type: Research Published on:

  38. We tested whether apoptotic adipose-derived mesenchymal stem cells (A-ADMSCs) were superior to healthy (H)-ADMSCs at attenuating organ damage and mortality in sepsis syndrome following cecal ligation and punct...

    Authors: Chia-Lo Chang, Steve Leu, Hsin-Ching Sung, Yen-Yi Zhen, Chung-Lung Cho, Angela Chen, Tzu-Hsien Tsai, Sheng-Ying Chung, Han-Tan Chai, Cheuk-Kwan Sun, Chia-Hung Yen and Hon-Kan Yip
    Citation: Journal of Translational Medicine 2012 10:244
    Content type: Research Published on:

  39. Ischemia is the major cause of acute kidney injury (AKI), associated with high mortality and morbidity. Mesenchymal stem cells (MSCs) have multilineage differentiation potential and can be a potent therapeutic...

    Authors: Muhammad Shareef Masoud, Sanam Saiqa Anwar, Muhammad Zeeshan Afzal, Azra Mehmood, Shaheen N Khan and Sheikh Riazuddin
    Citation: Journal of Translational Medicine 2012 10:243
    Content type: Research Published on:

  40. The secretory small GTPase Rab27b was recently identified as an oncogene in breast cancer (BC) in vivo and in vitro studies. This research was designed to further explore the clinical and prognostic significan...

    Authors: Jia-Xing Zhang, Xiao-Xia Huang, Man-Bo Cai, Zhu-Ting Tong, Jie-Wei Chen, Dong Qian, Yi-Ji Liao, Hai-Xia Deng, Ding-Zhun Liao, Ma-Yan Huang, Yi-Xin Zeng, Dan Xie and Shi-Juan Mai
    Citation: Journal of Translational Medicine 2012 10:242
    Content type: Research Published on:

  41. The use of large animals as an experimental model for novel treatment techniques has many advantages over the use of laboratory animals, so veterinary medicine is becoming an increasingly important translation...

    Authors: Darja Pavlin, Maja Cemazar, Gregor Sersa and Natasa Tozon
    Citation: Journal of Translational Medicine 2012 10:234
    Content type: Review Published on:

  42. Machine perfusion (MP) of kidney graft provides benefits against preservation injury, however decreased graft quality requires optimization of the method. We examined the chronic benefits of MP on kidney graft...

    Authors: Raphael Thuillier, Ricardo Codas, Etienne Marchand, Hubert Lathelize, Olivier Page, Alexandre Valagier, Lionel Badet and Thierry Hauet
    Citation: Journal of Translational Medicine 2012 10:233
    Content type: Research Published on:

  43. Despite the successes of recombinant hematopoietic-stimulatory factors at accelerating bone marrow reconstitution and shortening the neutropenic period post-transplantation, significant challenges remain such ...

    Authors: J Christopher Mizer, Thomas E Ichim, Doru T Alexandrescu, Constantin A Dasanu, Famela Ramos, Andrew Turner, Erik J Woods, Vladimir Bogin, Michael P Murphy, David Koos and Amit N Patel
    Citation: Journal of Translational Medicine 2012 10:231
    Content type: Review Published on:

  44. Numerous preclinical and clinical studies have investigated the regenerative potential and the trophic support of mesenchymal stem cells (MSCs) following their injection into a target organ. Clinicians favor t...

    Authors: Murali Krishna Mamidi, Gurbind Singh, Juani Mazmin Husin, Kavitha Ganesan Nathan, Gopinath Sasidharan, Zubaidah Zakaria, Ramesh Bhonde, Anish Sen Majumdar and Anjan Kumar Das
    Citation: Journal of Translational Medicine 2012 10:229
    Content type: Research Published on:

  45. GADD45B is a member of the growth arrest DNA damage-inducible gene family associated with cell growth control, apoptosis, and DNA damage repair response. The aim of this study is to detect the role of GADD45B ...

    Authors: Lisha Wang, Xiuying Xiao, Dali Li, Yayun Chi, Ping Wei, Yiqin Wang, Shujuan Ni, Cong Tan, Xiaoyan Zhou and Xiang Du
    Citation: Journal of Translational Medicine 2012 10:215
    Content type: Research Published on:

  46. Inactivaion of tumor suppressor genes (TSGs) by promoter CpG methylation frequently occurs in tumorigenesis, even in the early stages, contributing to the initiation and progression of human cancers. Deleted in l...

    Authors: Zhaohui Wang, Lili Li, Xianwei Su, Zifen Gao, Gopesh Srivastava, Paul G Murray, Richard Ambinder and Qian Tao
    Citation: Journal of Translational Medicine 2012 10:209
    Content type: Research Published on:

  47. Endometrial regenerative cells (ERC) and bone marrow stromal cells (BMSC) are being used in clinical trials. While they have been reported to have similar characteristics, they have not been directly compared.

    Authors: Huan Wang, Ping Jin, Marianna Sabatino, Jiaqiang Ren, Sara Civini, Vladimir Bogin, Thomas E Ichim and David F Stroncek
    Citation: Journal of Translational Medicine 2012 10:207
    Content type: Research Published on:

  48. Fork head box M1 (FoxM1) is a proliferation-associated transcription factor essential for cell cycle progression. Numerous studies have documented that FoxM1 has multiple functions in tumorigenesis and its ele...

    Authors: Yi-Jun Xue, Ri-Hai Xiao, Da-Zhi Long, Xiao-Feng Zou, Xiao-Ning Wang, Guo-Xi Zhang, Yuan-Hu Yuan, Geng-Qing Wu, Jun Yang, Yu-Ting Wu, Hui Xu, Fo-Lin Liu and Min Liu
    Citation: Journal of Translational Medicine 2012 10:200
    Content type: Research Published on:

  49. Embryonic stem cells (ESCs) are pluripotent stem cells and can form tumors containing cells from all three germ layers. Similarities between pluripotent stem cells and malignant tumor cells have been identifie...

    Authors: Xinrong Peng, Tao Liu, Ying Wang, Qiaoling Yan, Huajun Jin, Linfang Li, Qijun Qian and Mengchao Wu
    Citation: Journal of Translational Medicine 2012 10:196
    Content type: Research Published on:

  50. Adipose tissue is an attractive source of cells for therapeutic purposes because of the ease of harvest and the high frequency of mesenchymal stem cells (MSCs). Whilst it is clear that MSCs have significant th...

    Authors: Sinead P Blaber, Rebecca A Webster, Cameron J Hill, Edmond J Breen, Donald Kuah, Graham Vesey and Benjamin R Herbert
    Citation: Journal of Translational Medicine 2012 10:172
    Content type: Research Published on:
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