Skip to main content

Regenerative Medicine

Section edited by Francisco Silva

The field of regenerative medicine encompasses various strategies such as the use of materials and biologics to take the place or remodel compromised tissues, both structurally and functionally, in order to facilitate tissue healing. 

The ability to remodel tissue and organ microenvironments damaged by age, disease, or trauma has a tremendous impact on the current standard of care in treating patients suffering from various diseases. Over the past two decades, tissue engineering and regenerative medicine has emerged as an exciting path towards therapies.  An improved understanding of how age, environmental factors and the various stages of disease progression and their impact on the innate regeneration will also likely be important in advancing the field.

The section encourages contributions aimed at advancing the research and development and clinical translation in the field, and welcomes submissions of studies aimed at advancing the various technologies that encompass regenerative medicine, which ultimately will aid in the development and translation of novel therapies for those suffering from unmet medical needs.

  1. Pulsed electromagnetic fields (PEMFs) show promise as a treatment for knee osteoarthritis (KOA) by reducing inflammation and promoting chondrogenic differentiation of bone marrow-derived mesenchymal stem cells...

    Authors: Kangping Song, Jing Hu, Ming Yang, Yong Xia, Chengqi He, Yonghong Yang and Siyi Zhu
    Citation: Journal of Translational Medicine 2024 22:741
  2. The traumatic spinal cord injury (SCI) can cause immediate multi-faceted function loss or paralysis. Microglia, as one of tissue resident macrophages, has been reported to play a critical role in regulating in...

    Authors: Penghui Li, Junlong Zhao, Yangguang Ma, Liang Wang, Shiqian Liang, Fan Fan, Tiaoxia Wei, Lei Feng, Xueyu Hu, Yiyang Hu, Zhe Wang and Hongyan Qin
    Citation: Journal of Translational Medicine 2024 22:724
  3. Inadequate nerve regeneration and an inhibitory local microenvironment are major obstacles to the repair of spinal cord injury (SCI). The activation and differentiation fate regulation of endogenous neural ste...

    Authors: Cong Xing, Song Liu, Liyue Wang, Hongpeng Ma, Mi Zhou, Hao Zhong, Shibo Zhu, Qiang Wu and Guangzhi Ning
    Citation: Journal of Translational Medicine 2024 22:723
  4. Aging is a multifaceted process that affects all organ systems. With the increasing trend of population aging, aging-related diseases have resulted in significant medical challenges and socioeconomic burdens. ...

    Authors: Lu Wang, Zihui Deng, Yun Li, Yiqi Wu, Renqi Yao, Yuan Cao, Min Wang, Feihu Zhou, Hanyu Zhu and Hongjun Kang
    Citation: Journal of Translational Medicine 2024 22:722