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Computational modelling and Epidemiology

Section edited by Michael N. Liebman and Sabrina Molinaro

This section aims to allow rapid communication of methods and results that utilize computational modeling and epidemiologic approaches in translational medicine. The focus will be on population-based studies that extend towards more molecular level analysis. 

Submission of studies involving methods development is encouraged where actual application and results can be shown in the healthcare and life sciences domains. Among the approaches highlighted in this section are data-mining for health impact, data modeling, health record system design, applications of epidemiologic analysis, public policy evaluation, hypothesis evaluation and testing, risk assessment in healthcare and life sciences. These articles will describe the perspective on translational medicine where the approach and results reflect the computational modeling and epidemiologic aspects of this emerging area of research.

Featured articles

Impact of lockdown on Covid-19 case fatality rate and viral mutations spread in 7 countries in Europe and North America

Research | Maria Pachetti et al

Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach

Research | Syed Ovais Aftab et al


The effects of statins on dental and oral health: a review of preclinical and clinical studies

Review | Shabnam Tahamtan et al

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  1. Clozapine is highly effective in treatment-resistant schizophrenia, although, there remains significant variability in the response to this drug. To better understand this variability, the objective of this st...

    Authors: Claire H Li, Robert E Stratford Jr, Nieves Velez de Mendizabal, Thomas IFH Cremers, Bruce G Pollock, Benoit H Mulsant, Gary Remington and Robert R Bies
    Citation: Journal of Translational Medicine 2014 12:203
  2. Numerous inflammation-related pathways have been shown to play important roles in atherogenesis. Rapid and efficient assessment of the relative influence of each of those pathways is a challenge in the era of ...

    Authors: Héctor De León, Stéphanie Boué, Walter K Schlage, Natalia Boukharov, Jurjen W Westra, Stephan Gebel, Aaron VanHooser, Marja Talikka, R Brett Fields, Emilija Veljkovic, Michael J Peck, Carole Mathis, Vy Hoang, Carine Poussin, Renee Deehan, Katrin Stolle…
    Citation: Journal of Translational Medicine 2014 12:185
  3. Traditional Chinese Medicine Constitution (TCMC) refers to an integrated, metastable and natural specialty of individual in morphosis, physiological functions and psychological conditions. It is formed on the ...

    Authors: Youzhi Sun, Pei Liu, Yi Zhao, Lei Jia, Yanhua He, Steve An Xue, Xiao Zheng, Zhiyu Wang, Neng Wang and Jianping Chen
    Citation: Journal of Translational Medicine 2014 12:140
  4. Methicillin-resistant Staphylococcus aureus (MRSA) has been a deadly pathogen in healthcare settings since the 1960s, but MRSA epidemiology changed since 1990 with new genetically distinct strain types circulatin...

    Authors: Charles M Macal, Michael J North, Nicholson Collier, Vanja M Dukic, Duane T Wegener, Michael Z David, Robert S Daum, Philip Schumm, James A Evans, Jocelyn R Wilder, Loren G Miller, Samantha J Eells and Diane S Lauderdale
    Citation: Journal of Translational Medicine 2014 12:124
  5. Human diseases frequently cause complications such as obesity-induced diabetes and share numbers of pathological conditions, such as inflammation, by dysfunctions of common functional modules, such as protein–...

    Authors: Hyojung Paik, Hyoung-Sam Heo, Hyo-jeong Ban and Seong Beom Cho
    Citation: Journal of Translational Medicine 2014 12:99
  6. The clinical prediction of survival is among the most challenging tasks because it refers to the process whereby the medical team assimilates clinical data using subjective methods. The purpose of this prospec...

    Authors: Liu Hui, Liu Qigui, Ren Sashuang, Liu Xiliang and Luan Guihong
    Citation: Journal of Translational Medicine 2014 12:78
  7. Each year in China, 30,000 babies are born with congenital hearing impairment. However, the molecular etiology of hearing impairment in the Yunnan Province population where more than 52 minorities live has not...

    Authors: Feng Xin, Yongyi Yuan, Xiaoming Deng, Mingyu Han, Guojian Wang, Jiandong Zhao, Xue Gao, Jun Liu, Fei Yu, Dongyi Han and Pu Dai
    Citation: Journal of Translational Medicine 2013 11:312
  8. Integrative understanding of preclinical and clinical data is imperative to enable informed decisions and reduce the attrition rate during drug development. The volume and variety of data generated during drug...

    Authors: Lena Brynne, Anders Bresell and Niclas Sjögren
    Citation: Journal of Translational Medicine 2013 11:250
  9. A new section of the Journal of Translational Medicine is being introduced to encourage rapid communication of methods and results that utilize computational modeling and epidemiologic approaches in translational...

    Authors: Michael N Liebman and Sabrina Molinaro
    Citation: Journal of Translational Medicine 2012 10:210

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