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Cardiovascular, Metabolic and Lipoprotein Translation

Section edited by Nehal N. Mehta and Tommaso Angelone
© Juan Gärtner/ stock.adob

This section aims to speed mechanistic understanding, development of novel diagnostics and potential therapeutic targets within cardiovascular, metabolic diseases and lipoprotein diseases. The section is open to experiments involving cellular models, animal models, observational studies and clinical trials that are distinguished for their novelty in approach, design or indication, timeliness, and unique ability to translate laboratory concepts from the bench to the bedside.

Highest priority will be given to those manuscripts which are specifically focused on cardiovascular, metabolic and lipid disorders which enrich understanding of disease mechanism, novel therapeutics and state-of-the-art scientific technique.

Featured articles


Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study

Research | Yvonne Baumer et al


Comprehensive analysis of differential immunocyte infiltration and the potential ceRNA networks during epicardial adipose tissue development in congenital heart disease

Research | Li Ma et al


Extracellular vesicles in diabetes mellitus induce alterations in endothelial cell morphology and migration​​​​​​​

Research | Sharon F Wu et al

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  1. Ex-vivo normothermic perfusion strategies are a promising new instrument in organ transplantation. The perfusion conditions are designed to be protective however the artificial environment can induce a local i...

    Authors: Sarah A. Hosgood, Tom Moore, Theresa Kleverlaan, Tom Adams and Michael L. Nicholson
    Citation: Journal of Translational Medicine 2017 15:216
    Content type: Research Published on:

  2. Renal denervation (RDN) is a promising therapeutic method in cardiology. Its currently most investigated indication is resistant hypertension. Other potential indications are atrial fibrillation, type 2 diabet...

    Authors: Jean-Claude Lubanda, Miroslav Chochola, Mikuláš Mlček, Petr Neužil, Josef Marek, Štěpán Havránek, Sylvie Kuchynková, Zdeňka Fingrová, Kao-Hsuan Aimee Huang and Aleš Linhart
    Citation: Journal of Translational Medicine 2017 15:215
    Content type: Research Published on:

  3. Meaningful translational large animal models for cardiac diseases are indispensable for studying disease mechanisms, development of novel therapeutic strategies, and evaluation of potential drugs.

    Authors: Mariann Gyöngyösi, Noemi Pavo, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Georg Goliasch, Ljubica Mandic, Jutta Bergler-Klein, Alfred Gugerell, Andras Jakab, Zsuzsanna Szankai, Levente Toth, Rita Garamvölgyi, Gerald Maurer, Frederic Jaisser…
    Citation: Journal of Translational Medicine 2017 15:202
    Content type: Research Published on:

  4. MicroRNAs (miRNAs) are a class of regulatory RNAs that regulate gene expression post-transcriptionally. Little, however, is known on the expression profile of circulating miRNAs in Tetralogy of Fallot (TOF) pa...

    Authors: Masood Abu-Halima, Eckart Meese, Andreas Keller, Hashim Abdul-Khaliq and Tanja Rädle-Hurst
    Citation: Journal of Translational Medicine 2017 15:156
    Content type: Research Published on:

  5. Regular physical activity is recommended for patients with chronic heart failure to improve their functional capacity, and walking is a popular, effective, and safe form of physical activity. Pedometers have s...

    Authors: Tomas Vetrovsky, Michal Siranec, Jiri Parenica, Martin Griva, Jiri Stastny, Jan Precek, Radek Pelouch, Vaclav Bunc, Ales Linhart and Jan Belohlavek
    Citation: Journal of Translational Medicine 2017 15:153
    Content type: Protocol Published on:

  6. Diabetic nephropathy (DN) is a severe complication of diabetes mellitus (DM). Pancreas or islet transplantation has been reported to prevent the development of DN lesions and ameliorate or reverse existing glo...

    Authors: Yongwei Jiang, Wenjian Zhang, Shiqing Xu, Hua Lin, Weiguo Sui, Honglin Liu, Liang Peng, Qing Fang, Li Chen and Jinning Lou
    Citation: Journal of Translational Medicine 2017 15:147
    Content type: Research Published on:

  7. Radiolabeled RGD peptides detect αvβ3 integrin expression associated with angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied whether cardiac positron emission tomography (PET...

    Authors: Maria Grönman, Miikka Tarkia, Tuomas Kiviniemi, Paavo Halonen, Antti Kuivanen, Timo Savunen, Tuula Tolvanen, Jarmo Teuho, Meeri Käkelä, Olli Metsälä, Mikko Pietilä, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Anne Roivainen and Antti Saraste
    Citation: Journal of Translational Medicine 2017 15:144
    Content type: Research Published on:

  8. The endothelium is a key variable in the pathogenesis of atherosclerosis and its complications, particularly coronary artery disease (CAD). Current evidence suggests that the endothelial status can be regarded...

    Authors: Martino Deidda, Cristina Piras, Christian Cadeddu Dessalvi, Damiana Congia, Emanuela Locci, Federica Ascedu, Gianfranco De Candia, Mauro Cadeddu, Giorgio Lai, Raimondo Pirisi, Luigi Atzori and Giuseppe Mercuro
    Citation: Journal of Translational Medicine 2017 15:112
    Content type: Research Published on:

  9. The lack of early diagnosis, progression markers and effective pharmacological treatment has dramatic unfavourable effects on clinical outcomes in patients with peripheral artery disease (PAD). Addressing thes...

    Authors: Giorgio Aquila, Cinzia Fortini, Antonio Pannuti, Serena Delbue, Micaela Pannella, Marco Bruno Morelli, Cristiana Caliceti, Fausto Castriota, Monica de Mattei, Alessia Ongaro, Agnese Pellati, Pasquale Ferrante, Lucio Miele, Luigi Tavazzi, Roberto Ferrari, Paola Rizzo…
    Citation: Journal of Translational Medicine 2017 15:98
    Content type: Research Published on:

  10. A series of clinical trials have confirmed the correlation between vascular calcification (VC) and cardiovascular events and mortality. However, current treatments have little effects on the regression of VC. ...

    Authors: Adham Sameer A. Bardeesi, Jingwei Gao, Kun Zhang, Suntian Yu, Mengchao Wei, Pinming Liu and Hui Huang
    Citation: Journal of Translational Medicine 2017 15:95
    Content type: Review Published on:

  11. Cell loss and subsequent deterioration of contractile function are hallmarks of chronic heart failure (HF). While apoptosis has been investigated as a participant in the progression of HF, it is unlikely that ...

    Authors: Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy and Adriana Adameová
    Citation: Journal of Translational Medicine 2017 15:86
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:103

  12. Hypertrophic cardiomyopathy (HCM) patients with early repolarization (ER) pattern are at higher risk of ventricular arrhythmia, yet the genetic background of this situation has not been well investigated. Here...

    Authors: Yanhong Chen, Hector Barajas-Martinez, Dongxiao Zhu, Xihui Wang, Chonghao Chen, Ruijuan Zhuang, Jingjing Shi, Xueming Wu, Yijia Tao, Weidong Jin, Xiaoyan Wang and Dan Hu
    Citation: Journal of Translational Medicine 2017 15:78
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:101

  13. We aimed to determine the circulating miRNA expression profile associated with BAV and aortic dilation to provide diagnostic and prognostic biomarkers for BAV and/or aortic dilation.

    Authors: Neus Martínez-Micaelo, Raúl Beltrán-Debón, Isabel Baiges, Marta Faiges and Josep M. Alegret
    Citation: Journal of Translational Medicine 2017 15:76
    Content type: Research Published on:

  14. Congenital heart disease (CHD) is a common birth defect, and most cases occur sporadically. Mutations in key genes that are responsible for cardiac development could contribute to CHD. To date, the genetic cau...

    Authors: Yanyan Qian, Deyong Xiao, Xiao Guo, Hongbo Chen, Lili Hao, Xiaojing Ma, Guoying Huang, Duan Ma and Huijun Wang
    Citation: Journal of Translational Medicine 2017 15:69
    Content type: Research Published on:

  15. Cardioprotective value of ischemic post- (IPostC), remote (RIC) conditioning in acute myocardial infarction (AMI) is unclear in clinical trials. To evaluate cardioprotection, most translational animal studies ...

    Authors: Tamás Baranyai, Zoltán Giricz, Zoltán V. Varga, Gábor Koncsos, Dominika Lukovic, András Makkos, Márta Sárközy, Noémi Pávó, András Jakab, Csilla Czimbalmos, Hajnalka Vágó, Zoltán Ruzsa, Levente Tóth, Rita Garamvölgyi, Béla Merkely, Rainer Schulz…
    Citation: Journal of Translational Medicine 2017 15:67
    Content type: Research Published on:

  16. We previously demonstrated that endothelial microparticles (EMPs) are increased in mitral valve diseases and impair valvular endothelial cell function. Perioperative systemic inflammation is an important risk ...

    Authors: Ze-Bang Lin, Hong-Bo Ci, Yan Li, Tian-Pu Cheng, Dong-Hong Liu, Yan-Sheng Wang, Jun Xu, Hao-Xiang Yuan, Hua-Ming Li, Jing Chen, Li Zhou, Zhi-Ping Wang, Xi Zhang, Zhi-Jun Ou and Jing-Song Ou
    Citation: Journal of Translational Medicine 2017 15:4
    Content type: Research Published on:

  17. Thyroid hormones have been associated with renal dysfunction in cross-sectional studies. However, prospective studies exploring the effect of thyroid hormones on renal function decline were sparse and got cont...

    Authors: Xiaolin Huang, Lin Ding, Kui Peng, Lin Lin, Tiange Wang, Zhiyun Zhao, Yu Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Yufang Bi, Guang Ning and Min Xu
    Citation: Journal of Translational Medicine 2016 14:336
    Content type: Research Published on:

  18. Cyclin-dependent kinase inhibitor 2A/2B (CDKN2A/2B) near chromosome 9p21 have been associated with both atherosclerosis and artery calcification, but the underlying mechanisms remained largely unknown. Considerin...

    Authors: Shuyu Zhou, Yumeng Zhang, Li Wang, Zhizhong Zhang, Biyang Cai, Keting Liu, Hao Zhang, Minhui Dai, Lingli Sun, Xiaomeng Xu, Huan Cai, Xinfeng Liu, Guangming Lu and Gelin Xu
    Citation: Journal of Translational Medicine 2016 14:333
    Content type: Research Published on:

  19. Intrauterine growth restriction (IUGR) is a risk factor for hypertension (HT) and chronic renal disease (CRD). A reduction in the nephron number is proposed to be the underlying mechanism; however, the mechani...

    Authors: Farid Boubred, Laurent Daniel, Christophe Buffat, Michel Tsimaratos, Charles Oliver, Martine Lelièvre-Pégorier and Umberto Simeoni
    Citation: Journal of Translational Medicine 2016 14:331
    Content type: Research Published on:

  20. Cardiovascular diseases (CVD) are an important cause of death worldwide. Anthocyanins are a subgroup of flavonoids found in berries, flowers, fruits and leaves. In epidemiological and clinical studies, these p...

    Authors: Jordano Ferreira Reis, Valter Vinicius Silva Monteiro, Rafaelli de Souza Gomes, Matheus Moraes do Carmo, Glauber Vilhena da Costa, Paula Cardoso Ribera and Marta Chagas Monteiro
    Citation: Journal of Translational Medicine 2016 14:315
    Content type: Review Published on:

  21. Angiopoietin-2 (Ang-2), a ligand of the Tie-2 receptor, plays an important role in maintaining endothelial cells and in destabilizing blood vessels. Collateral artery growth (arteriogenesis) is a key adaptive ...

    Authors: Xiaoyong Tan, Kai Yan, Meiping Ren, Ni Chen, Yongjie Li, Xin Deng, Liqun Wang, Rong Li, Mao Luo, Yong Liu, Yan Liu and Jianbo Wu
    Citation: Journal of Translational Medicine 2016 14:306
    Content type: Research Published on:

  22. Previous studies have suggested that people with obesity showed elevated serum levels of leptin as well as lipid dysfunction and proprotein convertase subtilisin/kexin type 9 (PCSK9) played an important role i...

    Authors: Ying Du, Sha Li, Chuan-Jue Cui, Yan Zhang, Sheng-Hua Yang and Jian-Jun Li
    Citation: Journal of Translational Medicine 2016 14:276
    Content type: Research Published on:

  23. Research and development of new drugs requires both long time and high costs, whereas safety and tolerability profiles make the success rate of approval very low. Drug repurposing, applying known drugs and com...

    Authors: Junichi Ishida, Masaaki Konishi, Nicole Ebner and Jochen Springer
    Citation: Journal of Translational Medicine 2016 14:269
    Content type: Review Published on:

  24. Urtica dioica has traditionally been used in the management of cardiovascular disorders especially hypertension. The aim of this study was to explore pharmacological base of its use in...

    Authors: Rahila Qayyum, Hafiz Misbah-ud-Din Qamar, Shamim Khan, Umme Salma, Taous Khan and Abdul Jabbar Shah
    Citation: Journal of Translational Medicine 2016 14:254
    Content type: Research Published on:

  25. Understanding the underlying mechanism of thrombus formation and its components is critical for effective prevention and treatment of ischemic stroke. The generation of thrombotic clots requires conversion of ...

    Authors: Slaven Pikija, Vladimir Trkulja, Johannes Sebastian Mutzenbach, Mark R. McCoy, Patricia Ganger and Johann Sellner
    Citation: Journal of Translational Medicine 2016 14:250
    Content type: Research Published on:

  26. Although recent studies indicate that epicardial adipose tissue expresses brown fat-like genes, such as PGC1α, UCP1 and PRDM16, the association of these genes with type 2 diabetes mellitus (DM2) in coronary ar...

    Authors: Inmaculada Moreno-Santos, Luis Miguel Pérez-Belmonte, Manuel Macías-González, María José Mataró, Daniel Castellano, Miguel López-Garrido, Carlos Porras-Martín, Pedro L. Sánchez-Fernández, Juan José Gómez-Doblas, Fernando Cardona, Eduardo de Teresa-Galván and Manuel Jiménez-Navarro
    Citation: Journal of Translational Medicine 2016 14:243
    Content type: Research Published on:

  27. The Wellcome Trust, the World Health Organization, and cardiologists have advocated for the idea of a “polypill” containing multiple cardiovascular drugs to be co-formulated into a single pill for over a decad...

    Authors: Reed F. Beall, Jon-David R. Schwalm, Mark D. Huffman, Tara McCready, Salim Yusuf and Amir Attaran
    Citation: Journal of Translational Medicine 2016 14:242
    Content type: Research Published on:

  28. Hyperlipidemia is a major component of metabolic syndrome, and often predicts cardiovascular diseases. We developed a new therapeutic agent berberine compounds (BC), consisting of berberine, oryzanol and vitam...

    Authors: Meng Li, Xiangbing Shu, Hanchen Xu, Chunlei Zhang, Lili Yang, Li Zhang and Guang Ji
    Citation: Journal of Translational Medicine 2016 14:237
    Content type: Research Published on:

  29. Intra-operative cell salvage (CS) was reported to have no impairment on blood coagulation in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surge...

    Authors: Sheliang Shen, Jun Zhang, Wenyuan Wang, Jiayin Zheng and Yihong Xie
    Citation: Journal of Translational Medicine 2016 14:228
    Content type: Research Published on:

  30. Psoriasis is a chronic inflammatory disease of the skin and joints that may also have systemic inflammatory effects, including the development of cardiovascular disease (CVD). Multiple epidemiologic studies ha...

    Authors: S. Santilli, D. R. Kast, I. Grozdev, L. Cao, R. L. Feig, J. B. Golden, S. M. Debanne, R. C. Gilkeson, C. E. Orringer, T. S. McCormick, N. L. Ward, K. D. Cooper and N. J. Korman
    Citation: Journal of Translational Medicine 2016 14:217
    Content type: Research Published on:

  31. Endothelial dysfunction associated with hypercholesterolemia is an early event in atherosclerosis characterized by redox imbalance associated with high superoxide production and reduced nitric oxide (NO) and h...

    Authors: Daniele M. Guizoni, Gabriel G. Dorighello, Helena C. F. Oliveira, Maria A. Delbin, Marta H. Krieger and Ana P. Davel
    Citation: Journal of Translational Medicine 2016 14:213
    Content type: Research Published on:

  32. Aspirin (ASA) is the most widely used medicine to prevent cardiovascular diseases; however, the mechanisms by which ASA exerts its anti-proliferative effect remain not fully understood. This study was designed...

    Authors: Xin Guo, Lijin Yu, Min Chen, Tian Wu, Xiangdong Peng, Ren Guo and Bikui Zhang
    Citation: Journal of Translational Medicine 2016 14:211
    Content type: Research Published on:

  33. Macrophages play important roles in adipose tissue inflammation and its consequences. Unfortunately, a detailed description of the macrophage phenotypes in different human adipose tissues is not available.

    Authors: Ivana Kralova Lesna, Anna Kralova, Sona Cejkova, Jiri Fronek, Marek Petras, Alena Sekerkova, Filip Thieme, Libor Janousek and Rudolf Poledne
    Citation: Journal of Translational Medicine 2016 14:208
    Content type: Research Published on:

  34. Long noncoding RNAs (lncRNAs) are non-protein coding transcripts regulating a variety of physiological and pathological functions. However, their implication in heart failure is still largely unknown. The aim ...

    Authors: Simona Greco, Germana Zaccagnini, Alessandra Perfetti, Paola Fuschi, Rea Valaperta, Christine Voellenkle, Serenella Castelvecchio, Carlo Gaetano, Nicoletta Finato, Antonio Paolo Beltrami, Lorenzo Menicanti and Fabio Martelli
    Citation: Journal of Translational Medicine 2016 14:183
    Content type: Research Published on:

  35. Differentially expressed genes in the left atria of mitral regurgitation (MR) pigs have been linked to peroxisome proliferator-activated receptor (PPAR) signaling pathway in the KEGG pathway. However, specific...

    Authors: Mien-Cheng Chen, Jen-Ping Chang, Yu-Sheng Lin, Kuo-Li Pan, Wan-Chun Ho, Wen-Hao Liu, Tzu-Hao Chang, Yao-Kuang Huang, Chih-Yuan Fang and Chien-Jen Chen
    Citation: Journal of Translational Medicine 2016 14:157
    Content type: Research Published on:

  36. Hemodynamic load leads to cardiac hypertrophy and heart failure. While afterload (pressure overload) induces concentric hypertrophy, elevation of preload (volume overload) yields eccentric hypertrophy and is a...

    Authors: Belal A. Mohamed, Abdul R. Asif, Moritz Schnelle, Mohamed Qasim, Sara Khadjeh, Dawid Lbik, Peter Schott, Gerd Hasenfuss and Karl Toischer
    Citation: Journal of Translational Medicine 2016 14:149
    Content type: Research Published on:

  37. Integration of whole-heart activation simulations and inverse potential mapping (IPM) could benefit the guidance and planning of electrophysiological procedures. Routine clinical application requires a fast an...

    Authors: P. Bhagirath, A. W. M. van der Graaf, J. de Hooge, N. M. S. de Groot and M. J. W. Götte
    Citation: Journal of Translational Medicine 2016 14:147
    Content type: Methodology Published on:

  38. To investigate whether vascular endothelial growth factor B (VEGF-B) improves myocardial survival and cardiac stem cell (CSC) function in the ischemia–reperfusion (I/R) heart and promotes CSC mobilization and ...

    Authors: Guo-hua Li, Bin Luo, Yan-xia Lv, Fei Zheng, Lu Wang, Meng-xi Wei, Xian-yu Li, Lei Zhang, Jia-ning Wang, Shi-you Chen, Jun-Ming Tang and Xiaohua He
    Citation: Journal of Translational Medicine 2016 14:116
    Content type: Research Published on:

  39. Thoracic aortic aneurysms and dissections (TAAD) are silent but possibly lethal condition with up to 40 % of cases being hereditary. Genetic background is heterogeneous. Recently next-generation sequencing ena...

    Authors: J. K. Poninska, Z. T. Bilinska, M. Franaszczyk, E. Michalak, M. Rydzanicz, E. Szpakowski, A. Pollak, B. Milanowska, G. Truszkowska, P. Chmielewski, A. Sioma, H. Janaszek-Sitkowska, A. Klisiewicz, I. Michalowska, M. Makowiecka-Ciesla, P. Kolsut…
    Citation: Journal of Translational Medicine 2016 14:115
    Content type: Research Published on:

  40. The prevalence of hyperuricemia has increased dramatically during the past several decades. Studies indicating uric acid is an independent risk factor for hypertension did not sufficiently control for other kn...

    Authors: Fengjiang Wei, Ning Sun, Chunyou Cai, Shuzhi Feng, Jianli Tian, Wentao Shi, Weili Xu, Yaogang Wang, Xilin Yang and Wei-Dong Li
    Citation: Journal of Translational Medicine 2016 14:110
    Content type: Research Published on:

  41. Mammalian microRNAs (miR) regulate the expression of genes relevant for the development of adaptive and innate immunity against cancer. Since T cell dysfunction has previously been reported in patients with re...

    Authors: Margherita Gigante, Paola Pontrelli, Wolfgang Herr, Maddalena Gigante, Morena D’Avenia, Gianluigi Zaza, Elisabetta Cavalcanti, Matteo Accetturo, Giuseppe Lucarelli, Giuseppe Carrieri, Michele Battaglia, Walter J. Storkus, Loreto Gesualdo and Elena Ranieri
    Citation: Journal of Translational Medicine 2016 14:84
    Content type: Research Published on:

  42. Energy metabolism disorder is a critical process in lung ischemia–reperfusion injury (LIRI). This study was aimed to determine the effects of resolvin D1 (RvD1) on the energy metabolism in LIRI.

    Authors: Qifeng Zhao, Ji Wu, Qingwang Hua, Zhiyong Lin, Leping Ye, Weixi Zhang, Guowei Wu, Jie Du, Jie Xia, Maoping Chu and Xingti Hu
    Citation: Journal of Translational Medicine 2016 14:81
    Content type: Research Published on:

  43. To explore whether plasma fatty acids and SNPs in the fatty acid desaturase (FADS) gene associated with type 2 diabetes (T2D) and coronary artery disease (CAD).

    Authors: Si-Wei Li, Jin Wang, Ying Yang, Zhi-Jie Liu, Lin Cheng, Huan-Yu Liu, Pei Ma, Wan Luo and Song-Mei Liu
    Citation: Journal of Translational Medicine 2016 14:79
    Content type: Research Published on:

  44. Aspirin resistance established by different laboratory methods is still a debated problem. Using COX1 specific methods no aspirin resistance was detected among healthy volunteers. Here we tested the effect of ...

    Authors: Nóra Homoródi, Emese G. Kovács, Sarolta Leé, Éva Katona, Amir H. Shemirani, Gizella Haramura, László Balogh, Zsuzsanna Bereczky, Gabriella Szőke, Hajna Péterfy, Róbert G. Kiss, István Édes and László Muszbek
    Citation: Journal of Translational Medicine 2016 14:74
    Content type: Research Published on:

  45. Lower leg ischemia, myopathy, and limb dysfunction are distinguishing features of peripheral artery disease (PAD). The myopathy of PAD is characterized by myofiber degeneration in association with extracellula...

    Authors: Duy M. Ha, Lauren C. Carpenter, Panagiotis Koutakis, Stanley A. Swanson, Zhen Zhu, Mina Hanna, Holly K. DeSpiegelaere, Iraklis I. Pipinos and George P. Casale
    Citation: Journal of Translational Medicine 2016 14:39
    Content type: Research Published on:

  46. Endothelial progenitor cells (EPCs) contribute to recanalization of deep vein thrombosis (DVT). This study aimed to detect miRNA expression profiles in EPCs from patients with DVT and characterize the role of ...

    Authors: Lingshang Kong, Nan Hu, Xiaolong Du, Wenbin Wang, Hong Chen, Wendong Li, Sen Wei, Hao Zhuang, Xiaoqiang Li and Chenglong Li
    Citation: Journal of Translational Medicine 2016 14:23
    Content type: Research Published on:

  47. Heart failure with ejection fraction (HFpEF) is a syndrome resulting from several co-morbidities in which specific mediators are unknown. The platelet proteome responds to disease processes. We hypothesize tha...

    Authors: Roseanne Raphael, Diana Purushotham, Courtney Gastonguay, Marla A. Chesnik, Wai-Meng Kwok, Hsiang-En Wu, Sanjiv J. Shah, Shama P. Mirza and Jennifer L. Strande
    Citation: Journal of Translational Medicine 2016 14:18
    Content type: Research Published on:

  48. Psoriasis patients exhibit an increased risk of atherothrombotic events, including myocardial infarction and stroke. Clinical evidence suggests that psoriasis patients with early onset and more severe disease ...

    Authors: Jackelyn B. Golden, Yunmei Wang, Yi Fritz, Doina Diaconu, Xiufen Zhang, Sara M. Debanne, Daniel I. Simon, Thomas S. McCormick and Nicole L. Ward
    Citation: Journal of Translational Medicine 2015 13:382
    Content type: Research Published on:

  49. XBP1 is a key transcription factor of the unfolded protein response in mammalian cells, which is involved in several cardiovascular pathological progression including cardiac hypertrophy and myocardial infarct...

    Authors: Quanlu Duan, Chen Chen, Lei Yang, Ni Li, Wei Gong, Sheng Li and Dao Wen Wang
    Citation: Journal of Translational Medicine 2015 13:363
    Content type: Research Published on:

  50. Gamma-glutamyltransferase (GGT) is a well-established independent risk factor for cardiovascular mortality related to atherosclerotic disease. Four GGT fractions have been identified in plasma, but only b-GGT ...

    Authors: Eugenia Belcastro, Maria Franzini, Silvana Cianchetti, Evelina Lorenzini, Silvia Masotti, Vanna Fierabracci, Angela Pucci, Alfonso Pompella and Alessandro Corti
    Citation: Journal of Translational Medicine 2015 13:325
    Content type: Research Published on:
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