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  1. Cell–cell communications of various cell populations within tumor microenvironment play an essential role in primary tumor growth, metastasis evolution, and immune escape. Nevertheless, comprehensive investiga...

    Authors: Liu-xun Chen, Shen-jie Zeng, Xv-dong Liu, Hai-bin Tang, Jia-wu Wang and Qing Jiang
    Citation: Journal of Translational Medicine 2023 21:113
  2. Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a complex, heterogenous disease. It has been suggested that subgroups of people with ME/CFS exist, displaying a specific cluster of symptoms. In...

    Authors: Anouk W. Vaes, Maarten Van Herck, Qichen Deng, Jeannet M. Delbressine, Leonard A. Jason and Martijn A. Spruit
    Citation: Journal of Translational Medicine 2023 21:112
  3. Fibroblast growth factor receptor 3 is known as a favorable aim in vast range of cancers, particularly in bladder cancer treatment. Pharmacophore and QSAR modeling approaches are broadly utilized for developin...

    Authors: Mahmoud Ganji, Shohreh Bakhshi, Alireza Shoari and Reza Ahangari Cohan
    Citation: Journal of Translational Medicine 2023 21:111
  4. Preclinical evidence from us and others demonstrates that the anticancer effects of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors can be enhanced with focal radiation therapy (RT), but only when RT is delive...

    Authors: Vanessa Klapp, Aitziber Buqué, Norma Bloy, Ai Sato, Takahiro Yamazaki, Xi Kathy Zhou, Silvia C. Formenti, Lorenzo Galluzzi and Giulia Petroni
    Citation: Journal of Translational Medicine 2023 21:110
  5. Inadequate immunity caused by poor immune surveillance leads to tumorigenesis, while excessive immunity due to breakdown of immune tolerance causes autoimmune genesis. Although the function of immunity during ...

    Authors: Yuan Sui, Shuping Li, Xue-Qi Fu, Zhizhuang Joe Zhao and Shu Xing
    Citation: Journal of Translational Medicine 2023 21:109
  6. The prognosis of B-cell acute lymphoblastic leukemia (B-ALL) has improved significantly with current first-line therapy, although the recurrence of B-ALL is still a problem. Toll-like receptor 9 (TLR9) agonist...

    Authors: Ling Bai, Lei Zhou, Wei Han, Jingtao Chen, Xiaoyi Gu, Zheng Hu, Yongguang Yang, Wei Li, Xiaoying Zhang, Chao Niu, Yongchong Chen, Hui Li and Jiuwei Cui
    Citation: Journal of Translational Medicine 2023 21:108
  7. The incidence and mortality rate of gastrointestinal cancers are high worldwide. Increasing studies have illustrated that the occurrence, progression, metastasis and prognosis of cancers are intimately linked ...

    Authors: Weili Liu, Yuan Gao, Hua Li, Xinxing Wang, Min Jin, Zhiqiang Shen, Dong Yang, Xuelian Zhang, Zilin Wei, Zhaoli Chen and Junwen Li
    Citation: Journal of Translational Medicine 2023 21:107
  8. The Bacillus Calmette-Guérin (BCG) vaccine was discovered a century ago and has since been clinically applicable. BCG can not only be used for the prevention of tuberculosis, but also has a non-specific protec...

    Authors: Jingjing Chen, Li Gao, Xinya Wu, Yuxin Fan, Meixiao Liu, Li Peng, Jieqin Song, Bingxue Li, Aihua Liu and Fukai Bao
    Citation: Journal of Translational Medicine 2023 21:106
  9. The role of microRNA (miRNA) in modulating the function of cancer stem cells through diverse signaling pathway has been evidenced. We here identified a role of microRNA (miRNA) family, specifically miR-148/152...

    Authors: Xiaoying Li, Lin Li and Jiangying Wu
    Citation: Journal of Translational Medicine 2023 21:105
  10. Recent numerous epidemiology and clinical association studies reported that ApoE polymorphism might be associated with the risk and severity of coronavirus disease 2019 (COVID-19), and yielded inconsistent result...

    Authors: Feng Chen, Yanting Chen, Qiongwei Ke, Yongxiang Wang, Zheng Gong, Xiongjin Chen, Yujie Cai, Shengnan Li, Yuanhong Sun, Xiaoping Peng, Yao Ji, Tianzhen Zhang, Wenxian Wu, Lili Cui and Yan Wang
    Citation: Journal of Translational Medicine 2023 21:103
  11. In the past decades studies on anti-tumoral drugs inhibiting matrix metalloproteinase (MMPs) were disappointing. Recently, we demonstrated that mature endothelial cells (ECs) and endothelial colony forming cel...

    Authors: Anastasia Chillà, Cecilia Anceschi, Elena Frediani, Francesca Scavone, Tommaso Del Rosso, Giuseppe Pelagio, Antonio Tufaro, Giuseppe De Palma, Mario Del Rosso, Gabriella Fibbi, Paola Chiarugi, Anna Laurenzana and Francesca Margheri
    Citation: Journal of Translational Medicine 2023 21:102
  12. Renal denervation (RDN) was still performed without any intra-procedural method for nerve mapping. Whether renal nerve stimulation (RNS) is an efficient way to identify renal autonomic innervation and optimize...

    Authors: Hang Liu, Yidan Li, Hao Zhou, Weijie Chen, Yanping Xu, Huaan Du, Bo Zhang, Tianli Xia, Dan Li, Zhenhong Ou, Ruotian Tang, Qingsong Chen, Binyi Zhao and Yuehui Yin
    Citation: Journal of Translational Medicine 2023 21:100
  13. Osteosarcoma (OS) is the most frequent and aggressive primary malignant sarcoma among adolescents and chemotherapy has not substantially progressed for decades. New insights into OS development and therapeutic...

    Authors: Yifeng Sun, Chunming Zhang, Qiongxuan Fang, Wenqiang Zhang and Wei Liu
    Citation: Journal of Translational Medicine 2023 21:99
  14. An increased prevalence of psychiatric comorbidities (including depression and anxiety disorder) has been observed among patients with chronic fatigue syndrome (CFS). However, few studies have examined the pre...

    Authors: Chi Chen, Hei-Tung Yip, Kam-Hang Leong, Wei-Cheng Yao, Chung-Lieh Hung, Ching-Huang Su, Chien-Feng Kuo and Shin-Yi Tsai
    Citation: Journal of Translational Medicine 2023 21:98
  15. Atherosclerosis is driven by synergistic interactions between pathological biomechanical and lipid metabolic factors. Long noncoding RNAs (LncRNAs) have been implicated in atherogenesis. The purpose of this st...

    Authors: Yang Hong, Yue Zhang, Hui Chen, Xueqing Tang, Hongrui Zhao, Ziyu Meng, Xueling Jia, Wenfeng Liu, Xiaohan Li, Lin Wang, Xinrui Zhong, Xuefeng Bai, Heyang Sun, Philipp Kopylov, Bestavashvili Afina, Dmitry Shchekochikhin…
    Citation: Journal of Translational Medicine 2023 21:97
  16. Alterations in oral microbiota in patients with systemic lupus erythematosus (SLE) is less evaluated. The aim of this study was to compare the characteristics of the oral microbiome in SLE patients and healthy...

    Authors: Jinyan Guo, Guangying Cui, Wei Huang, Zhaohui Zheng, Tianfang Li, Guanmin Gao, Zhen Huang, Yuwei Zhan, Suying Ding, Shengyun Liu, Zujiang Yu and Zhigang Ren
    Citation: Journal of Translational Medicine 2023 21:95
  17. Endometrial cancer (EC) is a common gynecological cancer that endangers women health. Although substantial progresses of EC management have been achieved in recent years, the incidence of EC still remains high...

    Authors: Pengzhu Huang, Xiangqin Fan, Hongfei Yu, Kaiwen Zhang, Huanrong Li, Yingmei Wang and Fengxia Xue
    Citation: Journal of Translational Medicine 2023 21:94
  18. Gut microbiota plays a critical role in the onset and development of depression, but the underlying molecular mechanisms are unclear. This study was conducted to observe the characteristics of gut microbiota, ...

    Authors: Jing Xie, Qi Zhong, Wen-tao Wu and Jian-jun Chen
    Citation: Journal of Translational Medicine 2023 21:93
  19. The popular statistics-based Genome-wide association studies (GWAS) have provided deep insights into the field of complex disorder genetics. However, its clinical applicability to predict disease/trait outcome...

    Authors: Ashley J. W. Lim, C. Tera Tyniana, Lee Jin Lim, Justina Wei Lynn Tan, Ee Tzun Koh, Samuel S. Chong, Chiea Chuen Khor, Khai Pang Leong and Caroline G. Lee
    Citation: Journal of Translational Medicine 2023 21:92
  20. Length of stay (LOS) is an important metric for evaluating the management of inpatients. This study aimed to explore the factors impacting the LOS of inpatients with type-2 diabetes mellitus (T2DM) and develop...

    Authors: Juntao Tan, Zhengyu Zhang, Yuxin He, Yue Yu, Jing Zheng, Yunyu Liu, Jun Gong, Jianjun Li, Xin Wu, Shengying Zhang, Xiantian Lin, Yuxi Zhao, Xiaoxin Wu, Songjia Tang, Jingjing Chen and Wenlong Zhao
    Citation: Journal of Translational Medicine 2023 21:91
  21. Observational studies have found that both short and long sleep duration are associated with increased risk of metabolic syndrome (MetS). This study aimed to examine the associations of genetically determined ...

    Authors: Yannis Yan Liang, Jie Chen, Miaoguan Peng, Jiajin Zhou, Xinru Chen, Xiao Tan, Ningjian Wang, Huan Ma, Lan Guo, Jihui Zhang, Yun-Kwok Wing, Qingshan Geng and Sizhi Ai
    Citation: Journal of Translational Medicine 2023 21:90
  22. Albumin is the most abundant protein in serum and serves as a transporter of free fatty acids (FFA) in blood vessels. In type 2 diabetes mellitus (T2DM) patients, the reduced serum albumin level is a risk fact...

    Authors: Hongyi Liu, Anji Ju, Xuan Dong, Zongrui Luo, Jiaze Tang, Boyuan Ma, Yan Fu and Yongzhang Luo
    Citation: Journal of Translational Medicine 2023 21:89
  23. Little is known on the association of types of grains with mortality and the moderating effect of lifestyle on this association. This study aims to evaluate the single or joint associations of types of grains ...

    Authors: Yongjie Chen, Boran Sun, Caihong Wang, Keming Zhang, Wenli Lu and Guowei Huang
    Citation: Journal of Translational Medicine 2023 21:88
  24. Diabetic nephropathy (DN) is a complex disease involving the upregulation of many inflammation-related proteins. Alternative polyadenylation (APA), a crucial post-transcriptional regulatory mechanism, has been...

    Authors: Tingting Zhao, Dongdong Zhan, Shuang Qu, Song Jiang, Wenhua Gan, Weisong Qin, Chunxia Zheng, Fang Cheng, Yinghui Lu, Mingwei Liu, Jinsong Shi, Hongwei Liang, Yi Wang, Jun Qin, Ke Zen and Zhihong Liu
    Citation: Journal of Translational Medicine 2023 21:86
  25. Infantile hemangioma (IH) is the most common tumor among infants, but the exact pathogenesis of IH is largely unknown. Our previous study revealed that glucose metabolism may play an important role in the path...

    Authors: Kaiying Yang, Tong Qiu, Jiangyuan Zhou, Xue Gong, Xuepeng Zhang, Yuru Lan, Zixin Zhang and Yi Ji
    Citation: Journal of Translational Medicine 2023 21:85
  26. Gastric cancer (GC) is the third-leading cause of cancer-associated mortalities globally. The deregulation of circular RNAs (circRNAs) and microRNAs (miRNAs or miRs) is widely implicated in the pathogenesis an...

    Authors: Jun You, Yinan Chen, Donghan Chen, Yongwen Li, Tinghao Wang, Jingtao Zhu, Qingqi Hong and Qiyuan Li
    Citation: Journal of Translational Medicine 2023 21:83
  27. Our previous study showed that fucosyltransferase 2 (Fut2) deficiency is closely related to colitis. Colitis increases the risk for the development of colorectal cancer (CRC). This study aimed to investigate t...

    Authors: Weijun Wang, Xuelian Tang, Caihan Duan, Shuxin Tian, Chaoqun Han, Wei Qian, Xin Jiang, Xiaohua Hou and Rong Lin
    Citation: Journal of Translational Medicine 2023 21:82
  28. Sirtuin 3 (Sirt3) is a controversial regulator of carcinogenesis. It residents in the mitochondria and gradually decays during aging. In this study, we tried to investigate the role of Sirt3 in carcinogenesis ...

    Authors: Liyi Wu, Xinyi Yan, Ruibo Sun, Ye Ma, Wanyu Yao, Baogui Gao, Qingyuan Zhang, Junxiong You, Hao Wang, Qinrui Han and Xuegang Sun
    Citation: Journal of Translational Medicine 2023 21:81
  29. The systemic immune-inflammation index (SII) is a novel biomarker to predict the prognosis of some malignant tumors based on neutrophil, platelet, and lymphocyte counts. Evidence is scarce about the prognostic...

    Authors: Linghao Meng, Yujia Yang, Xu Hu, Ruohan Zhang and Xiang Li
    Citation: Journal of Translational Medicine 2023 21:79
  30. Acral melanoma (AM) is the most common subtype in Chinese melanoma patients with a very poor prognosis. However, our understanding of the disease pathogenesis and molecular landscape is limited by the few stud...

    Authors: Rong Huang, Gaigai Shen, Yu Ren, Kelin Zheng, Jiayu Wang, Yan Shi, Jiani C. Yin, Lanqun Qin, Guiying Zhang, Mengke Zhao, Xinyu Su, Luqiao Li, Fufeng Wang, Yang Shao, Baorui Liu and Zhengyun Zou
    Citation: Journal of Translational Medicine 2023 21:78
  31. Chronic inflammation is a well-known risk factor for the development of gastric cancer (GC). Nevertheless, the molecular mechanisms underlying inflammation-related GC progression are incompletely defined.

    Authors: Tingting Xu, Mengyan Xie, Xinming Jing, Huning Jiang, Xi Wu, Xinzhu Wang and Yongqian Shu
    Citation: Journal of Translational Medicine 2023 21:77
  32. Identifying candidates responsive to treatment is important in lupus nephritis (LN) at the renal flare (RF) because an effective treatment can lower the risk of progression to end-stage kidney disease. However...

    Authors: Ding-Jie Lee, Ping-Huang Tsai, Chien-Chou Chen and Yang-Hong Dai
    Citation: Journal of Translational Medicine 2023 21:76
  33. Metastatic castration-resistant prostate cancer remains a challenging condition to treat. Among the available therapeutic options, the androgen receptor signaling inhibitors abiraterone acetate plus prednisone...

    Authors: Pier Vitale Nuzzo, Filippo Pederzoli, Calogero Saieva, Elisa Zanardi, Giuseppe Fotia, Andrea Malgeri, Sabrina Rossetti, Loana Valenca Bueno, Livia Maria Q. S. Andrade, Anna Patrikidou, Ricardo Pereira Mestre, Mikol Modesti, Sandro Pignata, Giuseppe Procopio, Giuseppe Fornarini, Ugo De Giorgi…
    Citation: Journal of Translational Medicine 2023 21:75
  34. CD4+ cytotoxic T cells (CD4 CTLs) are CD4+ T cells with major histocompatibility complex-II-restricted cytotoxic function. Under pathologic conditions, CD4 CTLs hasten the development of autoimmune disease or vir...

    Authors: Ziyi Chen, Meng Zhang, Yufeng Liu, Zhe Chen, Ling Wang, Wenjuan Wang, Jincheng Wang, Mingqian He, Bingyin Shi and Yue Wang
    Citation: Journal of Translational Medicine 2023 21:74
  35. The correlation and difference in T-cell phenotypes between peripheral blood lymphocytes (PBLs) and the tumor immune microenvironment (TIME) in patients with gastric cancer (GC) is not clear. We aimed to chara...

    Authors: Jing Ma, Jianhui Li, Nan He, Meirui Qian, Yuanyuan Lu, Xin Wang and Kaichun Wu
    Citation: Journal of Translational Medicine 2023 21:73
  36. Enterococcus faecalis (Efa) has been shown to be a “driver bacteria” in the occurrence and development of colorectal cancer (CRC). This study aims to explore the effect of specific metabolites of Efa on CRC.

    Authors: Li Zhang, Jing Liu, Mingxia Deng, Xiangliu Chen, Lushun Jiang, Jiajie Zhang, Lisheng Tao, Wei Yu and Yunqing Qiu
    Citation: Journal of Translational Medicine 2023 21:72
  37. Patients suffering from chronic pain often also exhibit depression symptoms. Soluble epoxide hydrolase (sEH) inhibitors can decrease blood levels of inflammatory cytokines. However, whether inhibiting sEH sign...

    Authors: Ailin Luo, Zifeng Wu, Shan Li, Cindy B. McReynolds, Di Wang, Hanyu Liu, Chaoli Huang, Teng He, Xinying Zhang, Yuanyuan Wang, Cunming Liu, Bruce D. Hammock, Kenji Hashimoto and Chun Yang
    Citation: Journal of Translational Medicine 2023 21:71
  38. Periodontal ligament stem cells (PDLSCs) are important seed cells for tissue engineering to realize the regeneration of alveolar bone. Understanding the gene regulatory mechanisms of osteogenic lineage differe...

    Authors: Linglu Jia, Dongfang Li, Ya-Nan Wang, Dongjiao Zhang and Xin Xu
    Citation: Journal of Translational Medicine 2023 21:70
  39. Recurrence is common in glioblastoma multiforme (GBM) because of the infiltrative, residual cells in the tumor margin. Standard therapy for GBM consists of surgical resection followed by chemotherapy and radio...

    Authors: Hanwool Jeon, Joonho Byun, Hayeong Kang, Kyunggon Kim, Eunyeup Lee, Jeong Hoon Kim, Chang Ki Hong, Sang Woo Song, Young-Hoon Kim, Sangjoon Chong, Jae Hyun Kim, Soo Jeong Nam, Ji Eun Park and Seungjoo Lee
    Citation: Journal of Translational Medicine 2023 21:69
  40. Intratumoral microbial communities have been recently discovered to exist in a variety of cancers and have been found to be intricately involved in tumour progression. Therefore, investigating the profiles and...

    Authors: Yuting He, Qiyao Zhang, Xiao Yu, Shuijun Zhang and Wenzhi Guo
    Citation: Journal of Translational Medicine 2023 21:68
  41. Frailty, defined as physical performance impairment, is a common condition in older adults and can anticipate the development of sarcopenia, a geriatric syndrome characterized by loss of muscle strength and ma...

    Authors: Simone Agostini, Roberta Mancuso, Lorenzo Agostino Citterio, Gabriela Alexandra Mihali, Beatrice Arosio and Mario Clerici
    Citation: Journal of Translational Medicine 2023 21:67
  42. Diabetic cardiomyopathy (DCM) is one of the common cardiovascular complications of diabetes and a leading cause of death in diabetic patients. Mitochondrial metabolism and immune-inflammation are key for DCM p...

    Authors: Cheng Peng, Yanxiu Zhang, Xueyan Lang and Yao Zhang
    Citation: Journal of Translational Medicine 2023 21:66
  43. Cerebral small vessel disease (CSVD) is a systemic disease, affecting not only the brain, but also eyes and other organs. The total CSVD score is a tool for comprehensive evaluation of brain lesions in patient...

    Authors: Jia-lin Wang, Xue-ru Cheng, Zhao-yang Meng and Yan-ling Wang
    Citation: Journal of Translational Medicine 2023 21:65
  44. Nasopharyngeal carcinoma (NPC) is a kind of epithelial carcinoma that is common in East and Southeast Asia. Distant metastasis after radiotherapy remains the main cause of treatment failure and preradiotherapy...

    Authors: Xiaotian Xu, Fangze Wei, Lin Xiao, Runye Wu, Baojun Wei, Shengkai Huang, Junlin Yi and Wei Cui
    Citation: Journal of Translational Medicine 2023 21:64

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