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  1. Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) are three nervous system diseases that partially overlap clinically and genetically. However, bulk RNA-sequencing did not accurat...

    Authors: Li-Yuan Fan, Jing Yang, Ruo-Yu Liu, Ying Kong, Guang-Yu Guo and Yu-Ming Xu
    Citation: Journal of Translational Medicine 2023 21:649
  2. Memory B cells and microRNAs (miRNAs) play important roles in the progression of gastric adenocarcinoma (GAC), also known as stomach adenocarcinoma (STAD). However, few studies have investigated the use of mem...

    Authors: Ruquan Liu, Biaojie Huang, Yongzhao Shao, Yongming Cai, Xi Liu and Zhonglu Ren
    Citation: Journal of Translational Medicine 2023 21:648
  3. Cervical cancer is one of the most common gynecological cancers threatening women’s health worldwide. Double-stranded RNA-binding proteins (dsRBPs) regulate innate immunity and are therefore believed to be inv...

    Authors: Jin Li, Chong Wan, Xiaoqi Li, Chenlian Quan, Xiaoqiu Li and Xiaohua Wu
    Citation: Journal of Translational Medicine 2023 21:647
  4. The interest in targeted cancer therapies has been growing rapidly. While numerous cancer biomarkers and targeted treatment strategies have been developed and employed, there are still significant limitations ...

    Authors: Feihong Ren, Qiubai Jin, Tongtong Liu, Xuelei Ren and Yongli Zhan
    Citation: Journal of Translational Medicine 2023 21:646
  5. Inflammation in cardiac adipose tissue (AT) is associated with atherosclerosis. We investigated whether the epicardial-, pericardial and pre-sternal subcutaneous AT (EAT, PAT and SAT) expression of Sirtuin1 (S...

    Authors: Trine Baur Opstad, Bianca Papotti, Sissel Åkra, Charlotte Holst Hansen, Bjørn Braathen, Theis Tønnessen, Svein Solheim and Ingebjørg Seljeflot
    Citation: Journal of Translational Medicine 2023 21:644
  6. Despite immunotherapies having revolutionized the treatment of advanced cutaneous melanoma, effective and durable responses were only reported in a few patients. A better understanding of the interaction of me...

    Authors: Helene Schäfer, Karthikeyan Subbarayan, Chiara Massa, Christoforos Vaxevanis, Anja Mueller and Barbara Seliger
    Citation: Journal of Translational Medicine 2023 21:643
  7. Poor medication adherence contributes to increased morbidity and mortality in patients with epilepsy and may be under-addressed in clinical practice. Ethical concerns make it impossible to study the impact of ...

    Authors: Michelle Guignet, Amanda Campbell, Jonathan Vuong, Dale Whittington and H. Steve White
    Citation: Journal of Translational Medicine 2023 21:642
  8. Nowadays, the incidence rate of advanced and metastatic prostate cancer at the first time of diagnosis grows higher in China yearly. At present, androgen deprivation therapy (ADT) is the primary treatment of a...

    Authors: Ao Liu, Yi Gao, Qi Wang, Wenhao Lin, Zhiyang Ma, Xiaoqun Yang, Lu Chen and Danfeng Xu
    Citation: Journal of Translational Medicine 2023 21:641
  9. Idiopathic pulmonary fibrosis (IPF) is fibrotic lung disease with no effective treatment. It is characterized by destruction of alveolar structure and pulmonary interstitial fibrosis, leading to dyspnea and ev...

    Authors: Jie Ji, Shudan Zheng, Yuxin Liu, Tian Xie, Xiaoyu Zhu, Yang Nie, Yi Shen and Xiaodong Han
    Citation: Journal of Translational Medicine 2023 21:640
  10. Progressive peritoneal fibrosis is a worldwide public health concern impacting patients undergoing peritoneal dialysis (PD), yet there is no effective treatment. Our previous study revealed that a novel compou...

    Authors: Shuting Li, Congwei Luo, Sijia Chen, Yiyi Zhuang, Yue Ji, Yiqun Zeng, Yao Zeng, Xiaoyang He, Jing Xiao, Huizhen Wang, Xiaowen Chen, Haibo Long and Fenfen Peng
    Citation: Journal of Translational Medicine 2023 21:639
  11. A major obstacle to the development of personalized therapies for gastric cancer (GC) is the prevalent heterogeneity at the intra-tumor, intra-patient, and inter-patient levels. Although the pathological stage...

    Authors: Ziqian Deng, Ting Guo, Jiwang Bi, Gangjian Wang, Ying Hu, Hong Du, Yuan Zhou, Shuqin Jia, Xiaofang Xing and Jiafu Ji
    Citation: Journal of Translational Medicine 2023 21:638
  12. Anti-PD1/PDL1 immune checkpoint inhibitors (ICI) transformed the prognosis of patients with advanced non-small cell lung cancer (NSCLC). However, the response rate remains disappointing and toxicity may be lif...

    Authors: Alice Mogenet, Pascal Finetti, Emilie Denicolai, Laurent Greillier, Pascaline Boudou-Rouquette, François Goldwasser, Gwenael Lumet, Michele Ceccarelli, Daniel Birnbaum, Davide Bedognetti, Emilie Mamessier, Fabrice Barlesi, François Bertucci and Pascale Tomasini
    Citation: Journal of Translational Medicine 2023 21:637
  13. A large body of evidence indicates the existence of a complex pathophysiological relationship between cardiovascular diseases and cancer. Mitochondria are crucial organelles whose optimal activity is determine...

    Authors: Carmine Rocca, Teresa Soda, Ernestina Marianna De Francesco, Marco Fiorillo, Francesco Moccia, Giuseppe Viglietto, Tommaso Angelone and Nicola Amodio
    Citation: Journal of Translational Medicine 2023 21:635
  14. Preeclampsia (PE) is a leading cause of maternal and perinatal mortality and morbidity worldwide, but effective early prediction remains a challenge due to the lack of reliable biomarkers.

    Authors: Mingxi Liu, Yue Niu, Kongyang Ma, Peter C. K. Leung, Zi-Jiang Chen, Daimin Wei and Yan Li
    Citation: Journal of Translational Medicine 2023 21:634
  15. Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection, autoimmunity, chronic inf...

    Authors: Manuel Ruiz-Pablos, Bruno Paiva and Aintzane Zabaleta
    Citation: Journal of Translational Medicine 2023 21:633
  16. Ladinin-1 (LAD1), an anchoring filament protein, has been associated with several cancer types, including cancers of the colon, lungs, and breast. However, it is still unclear how and why LAD1 causes gastric c...

    Authors: Yingming Jiang, Yanchun Feng, Jintuan Huang, Zhenze Huang, Rongchang Tan, Tuoyang Li, Zijian Chen, Xiaocheng Tang, Jun Qiu, Chujun Li, Hao Chen and Zuli Yang
    Citation: Journal of Translational Medicine 2023 21:632
  17. Increasing evidence suggests that hepatocellular carcinoma (HCC) stem cells (LCSCs) play an essential part in HCC recurrence, metastasis, and chemotherapy and radiotherapy resistance. Multiple studies have dem...

    Authors: Rui Liang, Weifeng Hong, Yang Zhang, Di Ma, Jinwei Li, Yisong Shi, Qing Luo, Shisuo Du and Guanbin Song
    Citation: Journal of Translational Medicine 2023 21:631
  18. Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy. Neutrophil extracellular traps (NETs) are pathogen-trapping structures in the tumor microenvironment that affect DLBCL progression. However, t...

    Authors: Huizhong Shi, Yiming Pan, Guifen Xiang, Mingwei Wang, Yusong Huang, Liu He, Jue Wang, Qian Fang, Ling Li and Zhong Liu
    Citation: Journal of Translational Medicine 2023 21:630
  19. Vitamin D deficiency is common among the population, but its relationship with mortality of postmenopausal females is unclear. The aim of this study is to explore the association between serum 25-Hydroxyvitami...

    Authors: Jia-Wei Shi, Jiang-Nan Wu, Xiao-Yong Zhu, Wen-Hui Zhou, Jin-Ying Yang and Ming-Qing Li
    Citation: Journal of Translational Medicine 2023 21:629
  20. Owing to the heterogeneity of Alzheimer's disease (AD), its pathogenic mechanisms are yet to be fully elucidated. Evidence suggests an important role of metabolism in the pathophysiology of AD. Herein, we iden...

    Authors: Piaopiao Lian, Xing Cai, Cailin Wang, Ke Liu, Xiaoman Yang, Yi Wu, Zhaoyuan Zhang, Zhuoran Ma, Xuebing Cao and Yan Xu
    Citation: Journal of Translational Medicine 2023 21:628
  21. Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIR...

    Authors: Benluvankar Varghese, Ugo Chianese, Lucia Capasso, Veronica Sian, Paola Bontempo, Mariarosaria Conte, Rosaria Benedetti, Lucia Altucci, Vincenzo Carafa and Angela Nebbioso
    Citation: Journal of Translational Medicine 2023 21:627
  22. Fibroblast growth factor receptor (FGFR) gene family alterations are found in several cancers, indicating their importance as potential therapeutic targets. The FGFR-tyrosine kinase inhibitor (TKI) pemigatinib...

    Authors: Angelica Pace, Fabio Scirocchi, Chiara Napoletano, Ilaria Grazia Zizzari, Agnese Po, Francesca Megiorni, Angela Asquino, Paola Pontecorvi, Hassan Rahimi, Cinzia Marchese, Elisabetta Ferretti, Marianna Nuti and Aurelia Rughetti
    Citation: Journal of Translational Medicine 2023 21:626
  23. The hepatitis B virus X (HBx) protein is an established cause of hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC). Whether arginine methylation regulates ferroptosis involved in HBx-induced HCC p...

    Authors: Wensheng Deng, Jiaoyu Ai, Wanlin Zhang, Zhenyu Zhou, Muqi Li, Likun Yan, Lidong Zhang, Zongjing Huang, Ziyi Wu, Junhua Ai and Hai Jiang
    Citation: Journal of Translational Medicine 2023 21:625
  24. Triglyceride glucose index (TyG index) has been recommended as an alternative indicator of insulin resistance. However, the association between TyG and regression from prediabetes to normoglycemia remains to b...

    Authors: Xiaojie Chen, Danfeng Liu, Weiting He, Haofei Hu and Wenjian Wang
    Citation: Journal of Translational Medicine 2023 21:624
  25. Colorectal cancer (CRC) has become a global health problem which has almost highest morbidity and mortality in all types of cancers. This study aimed to uncover the biological functions and underlying mechanis...

    Authors: Shaojun Yu, Weixing Dai, Senlin Zhao, Yongzhi Yang, Ye Xu, Jianwei Wang, Qun Deng, Jinghu He and Debing Shi
    Citation: Journal of Translational Medicine 2023 21:623
  26. Biological ageing is tightly linked to cardiovascular disease (CVD). We aimed to investigate the relationship between Life’s Essential 8 (LE8), a currently updated measure of cardiovascular health (CVH), and b...

    Authors: Ronghuai Zhang, Min Wu, Wei Zhang, Xuna Liu, Jie Pu, Tao Wei, Zhanfang Zhu, Zhiguo Tang, Na Wei, Bo Liu, Qianwei Cui, Junkui Wang, Fuqiang Liu and Ying Lv
    Citation: Journal of Translational Medicine 2023 21:622
  27. Cancer is a complex disease with many contributing factors, and researchers have gained extensive knowledge that has helped them understand the diverse and varied nature of cancer. The altered patterns of DNA ...

    Authors: Chunjie Huang, Paniz Azizi, Masoud Vazirzadeh, Seyed Mohsen Aghaei-Zarch, Fatemehsadat Aghaei-Zarch, Jalaledin Ghanavi and Poopak Farnia
    Citation: Journal of Translational Medicine 2023 21:621
  28. A significant proportion of septic patients with acute lung injury (ALI) are recognized late due to the absence of an efficient diagnostic test, leading to the postponed treatments and consequently higher mort...

    Authors: Yongxin Zheng, Jinping Wang, Zhaoyi Ling, Jiamei Zhang, Yuan Zeng, Ke Wang, Yu Zhang, Lingbo Nong, Ling Sang, Yonghao Xu, Xiaoqing Liu, Yimin Li and Yongbo Huang
    Citation: Journal of Translational Medicine 2023 21:620
  29. In situ tumor vaccine has been gradually becoming a hot research field for its advantage of achieving personalized tumor therapy without prior antigen identification. Various in situ tumor vaccine regimens hav...

    Authors: Zhichen Sun, Yanhong Chu, Jie Xiao, Yueling Yang, Fanyan Meng, Xinyue Wang, Yanbing Dong, Junmeng Zhu, Yirong Wu, Lanqun Qin, Yaohua Ke, Baorui Liu and Qin Liu
    Citation: Journal of Translational Medicine 2023 21:619
  30. Gene expression signatures can be used as prognostic biomarkers in various types of cancers. We aim to develop a gene signature for predicting the response to radiotherapy in glioma patients.

    Authors: Xiaonan Zhang, Qiannan Ren, Zhiyong Li, Xiaolin Xia, Wan Zhang, Yue Qin, Dehua Wu and Chen Ren
    Citation: Journal of Translational Medicine 2023 21:618
  31. Vibrational spectroscopy can be a valuable tool to monitor the markers of cardiovascular diseases. In the present work, we explored the vibrational spectroscopy characteristics of the cardiac tissue in an expe...

    Authors: Leonardo Pioppi, Reza Parvan, Alan Samrend, Gustavo Jose Justo Silva, Marco Paolantoni, Paola Sassi and Alessandro Cataliotti
    Citation: Journal of Translational Medicine 2023 21:617
  32. Rheumatoid arthritis (RA) is a chronic inflammatory illness that mostly affects the joints of the hands and feet and can reduce life expectancy by an average of 3 to 10 years. Although tremendous progress has ...

    Authors: Yu Cao, Ying Yang, Qingfeng Hu and Guojun Wei
    Citation: Journal of Translational Medicine 2023 21:616
  33. IFN-λ has been shown to have a dual function in cancer, with its tumor-suppressive roles being well-established. However, the potential existence of a negative ‘‘tumor-promoting’’ effect of endogenous IFN-λ is...

    Authors: Zhen Zhen Wang, Xiao Ling Wen, Na Wang, Xu Hua Li, Yu Guo, Xu Zhu, Shu Heng Fu, Fei Fan Xiong, Jin Li, Limei Wang, Xiao Ling Gao and Hong Jiu Wang
    Citation: Journal of Translational Medicine 2023 21:615
  34. Peritoneal dialysis (PD) remains limited due to dialysis failure caused by peritoneal fibrosis. Tamoxifen (TAM), an inhibitor of estrogen receptor 1 (ESR1), has been reported to treat fibrosis, but the underly...

    Authors: Tingting Zhao, Zhengyu Sun, Xueli Lai, Hongtao Lu, Lulu Liu, Shuangxi Li, Ji-hang Yuan and Zhiyong Guo
    Citation: Journal of Translational Medicine 2023 21:614
  35. Mitochondrial dysfunction is reiteratively involved in the pathogenesis of diverse neurodegenerative diseases. Current in vitro and in vivo approaches support that mitochondrial dysfunction is branded by sever...

    Authors: Felipe A. Bustamante-Barrientos, Noymar Luque-Campos, María Jesús Araya, Eliana Lara-Barba, Javiera de Solminihac, Carolina Pradenas, Luis Molina, Yeimi Herrera-Luna, Yildy Utreras-Mendoza, Roberto Elizondo-Vega, Ana María Vega-Letter and Patricia Luz-Crawford
    Citation: Journal of Translational Medicine 2023 21:613
  36. Distant metastasis remains a leading cause of mortality among patients with colorectal cancer (CRC). Organotropism, referring to the propensity of metastasis to target specific organs, is a well-documented phe...

    Authors: Kai He, Zhihan Wang, Maochao Luo, Bowen Li, Ning Ding, Lei Li, Bo He, Han Wang, Jiangjun Cao, Canhua Huang, Jun Yang and Hai-Ning Chen
    Citation: Journal of Translational Medicine 2023 21:612
  37. Recurrent or metastatic cervical cancer (r/m CC) often has poor prognosis owing to its limited treatment options. The development of novel therapeutic strategies has been hindered by the lack of preclinical mo...

    Authors: Liting Liu, Min Wu, Anni Huang, Chun Gao, Yifan Yang, Hong Liu, Han Jiang, Long Yu, Yafei Huang and Hui Wang
    Citation: Journal of Translational Medicine 2023 21:611
  38. Identifying response markers is highly needed to guide the treatment strategy in patients with metastatic melanoma.

    Authors: Domenico Mallardo, Mario Fordellone, Andrew White, Margaret Ottaviano, Francesca Sparano, Michael Bailey, Arianna Bianca Facchini, Sufey Ong, Piera Maiolino, Corrado Caracò, Sarah Church, Ernesta Cavalcanti, Sarah Warren, Alfredo Budillon, Alessandra Cesano, Ester Simeone…
    Citation: Journal of Translational Medicine 2023 21:610
  39. Vascularized composite allotransplantation can improve quality of life and restore functionality. However, the complex tissue composition of vascularized composite allografts (VCAs) presents unique clinical ch...

    Authors: Carolyn Ton, Sara Salehi, Sara Abasi, John R. Aggas, Renee Liu, Gerald Brandacher, Anthony Guiseppi-Elie and Warren L. Grayson
    Citation: Journal of Translational Medicine 2023 21:609
  40. Assisted reproductive technologies (ART) have increased the incidence of multiple births, which can have a negative impact on maternal and offspring health. The study aimed to investigate the association betwe...

    Authors: Yi Jiang, Yuanyuan Du, Rui Su, Xuan Zhou, Lijie Wei, Jingyi Zhang, Shenglan Zhu, Huiting Zhang, Chenyun Fang, Yuting Chen, Peng Gao, Liangnan Zhang, Shaoshuai Wang, Jun Yu, Mengzhou He, Wencheng Ding…
    Citation: Journal of Translational Medicine 2023 21:608
  41. Non-union formation represents a major complication in trauma and orthopedic surgery. The phosphodiesterase-5 (PDE-5) inhibitor sildenafil has been shown to exert pro-angiogenic and pro-osteogenic effects in v...

    Authors: Maximilian M. Menger, David Bauer, Michelle Bleimehl, Claudia Scheuer, Benedikt J. Braun, Steven C. Herath, Mika F. Rollmann, Michael D. Menger, Matthias W. Laschke and Tina Histing
    Citation: Journal of Translational Medicine 2023 21:607
  42. The identifying of B-cell lymphoma 2 (Bcl-2) as a therapeutic target has led to a paradigm shift in acute myeloid leukemia (AML) treatment. Pyroptosis is a novel antitumor therapeutic mechanism due to its cyto...

    Authors: Fanghua Ye, Wen Zhang, Chenying Fan, Jiajia Dong, Min Peng, Wenjun Deng, Hui Zhang and Liangchun Yang
    Citation: Journal of Translational Medicine 2023 21:606
  43. Glycolysis under normoxic conditions, known as the Warburg effect, confers a selective advantage for the survival and proliferation of many tumors. In this study, we investigated the role of estrogen-related r...

    Authors: Tianxiao Wang, Yongjun Zhu, Lu Chen, WenXin Zhang, Huijie Qi, Xiaojin Shi, Mingkang Zhong, Haifei Chen and Qunyi Li
    Citation: Journal of Translational Medicine 2023 21:605
  44. Neuroblastoma (NB) and pheochromocytoma/paraganglioma (PHEO/PGL) are neuroendocrine tumors. Imaging of these neoplasms is performed by scintigraphy after injection of radiolabeled meta-iodobenzylguanidine (mIBG),...

    Authors: Joana Grand-Guillaume, Rosalba Mansi, Raghuvir H. Gaonkar, Sandra Zanger, Melpomeni Fani, Philippe J. Eugster, Maja Beck Popovic, Eric Grouzmann and Karim Abid
    Citation: Journal of Translational Medicine 2023 21:604
  45. The early differential diagnosis between bacterial meningitis (BM) and tuberculous meningitis (TBM) or cryptococcal meningitis (CM) remains a significant clinical challenge. Neutrophil Gelatinase-Associated Li...

    Authors: Qi Wang, Qingwen Lin, Haiyan Wang, Minjie Tang, Kengna Fan, Zeqin Zhang, Er Huang, Weiqing Zhang, Fengqing Wang, Qishui Ou and Xiaofeng Liu
    Citation: Journal of Translational Medicine 2023 21:603
  46. Cell-based strategies focusing on replacement or protection of dopaminergic neurons have been considered as a potential approach to treat Parkinson’s disease (PD) for decades. However, despite promising precli...

    Authors: Fang Wang, Zhengwu Sun, Daoyong Peng, Shikha Gianchandani, Weidong Le, Johannes Boltze and Shen Li
    Citation: Journal of Translational Medicine 2023 21:601
  47. A chromobox homologue 3 (CBX3) is elevated in various cancers and significantly contributes to the promotion of malignant behavior; despite this, its exact involvement in clear cell renal cell carcinoma (ccRCC...

    Authors: Jiasheng Chen, Yuxin Lin, Shukai zheng, Qingshan Chen, Shijie Tang and Xiaoping Zhong
    Citation: Journal of Translational Medicine 2023 21:600

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