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  1. Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammatory reactions and tissue damage in the joints. Long-term drug use in clinical practice is often accompanied by adverse reactions. Ex...

    Authors: Yuwei Lin, Zhanrui Cheng, Yan Zhong, Yinting Zhao, Guifen Xiang, Ling Li, Li Tian and Zhong Liu
    Citation: Journal of Translational Medicine 2024 22:305
  2. The treatment of spinal cord injury (SCI) has always been a significant research focus of clinical neuroscience, with inhibition of microglia-mediated neuro-inflammation as well as oxidative stress key to succ...

    Authors: Yanan Zhang, Qian Deng, Hongxiang Hong, Zhanyang Qian, Bowen Wan and Mingjie Xia
    Citation: Journal of Translational Medicine 2024 22:304
  3. Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by fluctuating muscle weakness. Despite the availability of established therapies, the management of MG symptoms remains suboptimal, partia...

    Authors: Jiao Li, Fei Wang, Zhen Li, Jingjing Feng, Yi Men, Jinming Han, Jiangwei Xia, Chen Zhang, Yilai Han, Teng Chen, Yinan Zhao, Sirui Zhou, Yuwei Da, Guoliang Chai and Junwei Hao
    Citation: Journal of Translational Medicine 2024 22:302
  4. Due to their complexity and to the presence of common clinical features, differentiation between asthma and chronic obstructive pulmonary disease (COPD) can be a challenging task, complicated in such cases als...

    Authors: Serena Correnti, Mariaimmacolata Preianò, Fabia Gamboni, Daniel Stephenson, Corrado Pelaia, Girolamo Pelaia, Rocco Savino, Angelo D’Alessandro and Rosa Terracciano
    Citation: Journal of Translational Medicine 2024 22:301

    The Publisher Correction to this article has been published in Journal of Translational Medicine 2024 22:334

  5. Crohn's disease (CD) is a disease characterized by intestinal immune dysfunction, often accompanied by metabolic abnormalities. Disturbances in lactate metabolism have been found in the intestine of patients w...

    Authors: Jingtong Wu, Yinyin Lv, Pei Hao, Ziyi Zhang, Yongtian Zheng, Ermei Chen and Yanyun Fan
    Citation: Journal of Translational Medicine 2024 22:300
  6. The progression of gallbladder cancer (GBC) is accompanied by abnormal fatty acid β-oxidation (FAO) metabolism. Different types of lipids perform various biological functions. This study aimed to determine the...

    Authors: Yang Yang, Huaifeng Li, Ke Liu, Lu Zou, Shanshan Xiang, Yajun Geng, Xuechuan Li, Shimei Qiu, Jiahua Yang, Xuya Cui, Lin li, Yang Li, Weijian Li, Siyuan Yan, Liguo Liu, Xiangsong Wu…
    Citation: Journal of Translational Medicine 2024 22:299
  7. Diabetic retinopathy (DR) is the foremost cause of vision loss among the global working-age population, and statins are among the most frequently prescribed drugs for lipid management in patients with DR. The ...

    Authors: Chengming Chen, Huan Zhang, Yanyan Lan, Weiming Yan, Sida Liu, Yixuan Chen, Tingke Xie, Jiayi Ning, Xiaolong Yan, Lei Shang and Jing Han
    Citation: Journal of Translational Medicine 2024 22:298
  8. The aberrant secretion and excessive deposition of type I collagen (Col1) are important factors in the pathogenesis of myocardial fibrosis in dilated cardiomyopathy (DCM). However, the precise molecular mechan...

    Authors: Hongjie Shi, Ming Yuan, Jie Cai, Lan Lan, Yumou Wang, Wei Wang, Jianliang Zhou, Bin Wang, Wenjun Yu, Zhe Dong, Dawei Deng, Qiaofeng Qian, Yang Li, Xianwu Zhou and Jinping Liu
    Citation: Journal of Translational Medicine 2024 22:297
  9. Authors: William Humphries, Yongtao Wang, Wei Qiao, Chantal Reina-Ortiz, Mohamed K. Abou-Ghazal, Lamonne M. Crutcher, Jun Wei, Ling-Yuan Kong, Raymond Sawaya, Ganesh Rao, Jeffrey Weinberg, Sujit S. Prabhu, Gregory N. Fuller and Amy B. Heimberger
    Citation: Journal of Translational Medicine 2024 22:296

    The original article was published in Journal of Translational Medicine 2009 7:92

  10. Bladder cancer (BC) is the most common urinary tract malignancy. Aurora kinase B (AURKB), a component of the chromosomal passenger protein complex, affects chromosomal segregation during cell division. Mitotic...

    Authors: Linzhi Li, Pengcheng Jiang, Weimin Hu, Fan Zou, Ming Li, Ting Rao, Yuan Ruan, Weimin Yu, Jinzhuo Ning and Fan Cheng
    Citation: Journal of Translational Medicine 2024 22:295
  11. Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health and undeniable taste that facilitated a widespread popularity...

    Authors: Justyna Godos, Francesca Scazzina, Corrado Paternò Castello, Francesca Giampieri, José L. Quiles, Mercedes Briones Urbano, Maurizio Battino, Fabio Galvano, Licia Iacoviello, Giovanni de Gaetano, Marialaura Bonaccio and Giuseppe Grosso
    Citation: Journal of Translational Medicine 2024 22:294
  12. Regulatory T cells (Tregs) expressing the transcription factor FoxP3 are essential for maintaining immunological balance and are a significant component of the immunosuppressive tumor microenvironment (TME). S...

    Authors: Yu Li, Cangang Zhang, Aimin Jiang, Anqi Lin, Zaoqu Liu, Xiangshu Cheng, Wanting Wang, Quan Cheng, Jian Zhang, Ting Wei and Peng Luo
    Citation: Journal of Translational Medicine 2024 22:293
  13. Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the ...

    Authors: Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. Romero, Francois J. Villinger, Armando G. Burgos…
    Citation: Journal of Translational Medicine 2024 22:292
  14. Biologic TNF-α inhibitors (bTNFIs) can block cerebral TNF-α in Alzheimer’s disease (AD) if these macromolecules can cross the blood–brain barrier (BBB). Thus, a model bTNFI, the extracellular domain of type II...

    Authors: Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar, Joshua Yang, Sanjana Kolluru and Rachita K. Sumbria
    Citation: Journal of Translational Medicine 2024 22:291
  15. Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common organelle existing in most mammal cells, and its complex and dynamic functions in maintaining redox and metabolic balance, regu...

    Authors: Boer Deng, Weimin Kong, Xiaochang Shen, Chao Han, Ziyi Zhao, Shuning Chen, Chunxiao Zhou and Victoria Bae-Jump
    Citation: Journal of Translational Medicine 2024 22:290
  16. Global myopia prevalence poses a substantial public health burden with vision-threatening complications, necessitating effective prevention and control strategies. Precise prediction of spherical equivalent (S...

    Authors: Jing Zhao, Yanze Yu, Yiming Li, Feng Li, Zhe Zhang, Weijun Jian, Zhi Chen, Yang Shen, Xiaoying Wang, Zhengqiang Ye, Chencui Huang and Xingtao Zhou
    Citation: Journal of Translational Medicine 2024 22:289
  17. Non-small cell lung cancer (NSCLC) often exhibits resistance to radiotherapy, posing significant treatment challenges. This study investigates the role of SMAD3 in NSCLC, focusing on its potential in influenci...

    Authors: Fushi Han, Shuzhen Chen, Kangwei Zhang, Kunming Zhang, Meng Wang and Peijun Wang
    Citation: Journal of Translational Medicine 2024 22:288
  18. Protein cysteine oxidation is substantially involved in various biological and pathogenic processes, but its implications in pancreatic cancer development remains poorly understood.

    Authors: Chaochao Tan, Lichun Chen, Xiaoyu Guan, Wenyi Huang, Yinhong Feng, Ziyi Li, Ling Wu, Xiangping Huang, Qianhui Ouyang, Sixiang Liu, Ying Huang and Jiliang Hu
    Citation: Journal of Translational Medicine 2024 22:287
  19. Osteoarthritis (OA) is a degenerative disease characterized by chronic inflammation of the joint. As the disease progresses, patients will gradually develop symptoms such as pain, physical limitations and even...

    Authors: Chunran Pan, Fan Lu, Xiaoxia Hao, Xiaofeng Deng, Jiawei Liu, Kai Sun, Wenjie Hou, Xingru Shang, Ruimin Chi, Fengjing Guo and Tao Xu
    Citation: Journal of Translational Medicine 2024 22:286
  20. Lactate is traditionally recognized as a by-product of anaerobic metabolism. However, lactate is a preferred oxidative substrate for stressed myocardium. Exogenous lactate infusion increases cardiac output (CO...

    Authors: Oskar Kjærgaard Hørsdal, Niels Moeslund, Kristoffer Berg-Hansen, Roni Nielsen, Niels Møller, Hans Eiskjær, Henrik Wiggers and Nigopan Gopalasingam
    Citation: Journal of Translational Medicine 2024 22:285
  21. Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition characterized by severe gut inflammation, commonly presenting as Crohn’s disease, ulcerative colitis or categorized as IBD- unclassified...

    Authors: Manoj Kumar, Selvasankar Murugesan, Nazira Ibrahim, Mamoun Elawad and Souhaila Al Khodor
    Citation: Journal of Translational Medicine 2024 22:284
  22. The activation of glycolysis, particularly in the context of reprogrammed energy metabolism, is increasingly recognized as a significant characteristic of cancer. However, the precise mechanisms by which glyco...

    Authors: Wei Zhou, Mengyuan Tang, Dan He, Yi Shen, Ziwei Huang, Wenxin Xia, Zhiyun Wu, Wenxiang Wei, Hui Zheng, Qi Wang, Weifeng Shi and Jingting Jiang
    Citation: Journal of Translational Medicine 2024 22:283
  23. Oral inflammatory diseases are localized infectious diseases primarily caused by oral pathogens with the potential for serious systemic complications. However, publicly available datasets for these diseases ar...

    Authors: Weiyin Lin, Hong Yang, Jiayu Lin, Xia Yang, Zhihao Liao, Yifan Zheng, Peng Luo and Chufeng Liu
    Citation: Journal of Translational Medicine 2024 22:282
  24. Osteoarthritis (OA) is a multifactorial, hypertrophic, and degenerative condition involving the whole joint and affecting a high percentage of middle-aged people. It is due to a combination of factors, althoug...

    Authors: Maria Claudia Costa, Claudia Angelini, Monica Franzese, Concetta Iside, Marco Salvatore, Luigi Laezza, Francesco Napolitano and Michele Ceccarelli
    Citation: Journal of Translational Medicine 2024 22:281
  25. Ovarian cancer (OC) is distinguished by its aggressive nature and the limited efficacy of current treatment strategies. Recent studies have emphasized the significant role of cancer-associated fibroblasts (CAF...

    Authors: Songwei Feng, Bo Ding, Zhu Dai, Han Yin, Yue Ding, Sicong Liu, Ke Zhang, Hao Lin, Zhongdang Xiao and Yang Shen
    Citation: Journal of Translational Medicine 2024 22:280
  26. LILRB3, a member of the leukocyte immunoglobulin-like receptor B (LILRB) family, has immunosuppressive functions and directly regulates cancer development, which indicates that LILRB3 is an attractive target f...

    Authors: Qingyan Cen, Jianyu Chen, Jiaxin Guo, Mu Chen, Hao Wang, Suwan Wu, Honghao Zhang, Xiaoling Xie and Yuhua Li
    Citation: Journal of Translational Medicine 2024 22:278
  27. Authors: Kai Horny, Christoph Sproll, Lukas Peiffer, Frauke Furtmann, Patricia Gerhardt, Jan Gravemeyer, Nikolas H. Stoecklein, Ivelina Spassova and Jürgen C. Becker
    Citation: Journal of Translational Medicine 2024 22:277

    The original article was published in Journal of Translational Medicine 2023 21:267

  28. CLAD (Chronic Lung Allograft Dysfunction) remains a serious complication following lung transplantation. Some evidence shows that portions of Extracorporeal Photopheresis (ECP)-treated patients improve/stabili...

    Authors: Sara Bozzini, Eleonora Bozza, Cecilia Bagnera, Claudia Del Fante, Eugenio Barone, Simona De Vitis, Mara De Amici, Giorgia Testa, Stefania Croce, Chiara Valsecchi, Maria A Avanzini, Rosalia Cacciatore, Cristina Mortellaro, Gianluca Viarengo, Cesare Perotti and Federica Meloni
    Citation: Journal of Translational Medicine 2024 22:276
  29. The prognostic significance of myelofibrosis (MF) grade in patients with myelodysplastic syndrome (MDS) following an allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains elusive.

    Authors: Panpan Zhu, Xiaoyu Lai, Lizhen Liu, Jimin Shi, Jian Yu, Yanmin Zhao, Luxin Yang, Tingting Yang, Weiyan Zheng, Jie Sun, Wenjun Wu, Yi Zhao, Zhen Cai, He Huang and Yi Luo
    Citation: Journal of Translational Medicine 2024 22:275
  30. Chimeric antigen receptor natural killer (CAR-NK) cells represent a promising advancement in CAR cell therapy, addressing limitations observed in CAR-T cell therapy. However, our prior study revealed challenge...

    Authors: Na Yang, Caili Zhang, Yingchun Zhang, Yuting Fan, Jing Zhang, Xiaojin Lin, Ting Guo, Yangzuo Gu, Jieheng Wu, Jianmei Gao, Xing Zhao and Zhixu He
    Citation: Journal of Translational Medicine 2024 22:274
  31. Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade cytokine release syndrome (CRS) and immune e...

    Authors: Thomas Poiret, Sara Vikberg, Esther Schoutrop, Jonas Mattsson and Isabelle Magalhaes
    Citation: Journal of Translational Medicine 2024 22:273
  32. In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress. Moreover, polymerase-specific T cells exhi...

    Authors: Yan Jia, Jianing Zhao, Chunqing Wang, Jing Meng, Liqing Zhao, Hongwei Yang and Xiaoqing Zhao
    Citation: Journal of Translational Medicine 2024 22:272
  33. Patients with spondyloarthritis (SpA)/HLA-B27-associated acute anterior uveitis (AAU) experience recurring acute flares, which pose significant visual and financial challenges. Despite established links betwee...

    Authors: Shuming Chen, Weidi Huang, Qiaoqian Wan, Zichun Tang, Xie Li, Fang Zeng, Shuyan Zheng, Zhuo Li and Xiao Liu
    Citation: Journal of Translational Medicine 2024 22:271
  34. Most anti-cancer modalities are designed to directly kill cancer cells deploying mechanisms of action (MOAs) centered on the presence of a precise target on cancer cells. The efficacy of these approaches is li...

    Authors: Joyce Hu, Paolo Ascierto, Alessandra Cesano, Volker Herrmann and Francesco M. Marincola
    Citation: Journal of Translational Medicine 2024 22:270
  35. Chemotherapy is a primary treatment for cancer, but its efficacy is often limited by cancer-associated bacteria (CAB) that impair tumor suppressor functions. Our previous research found that Mycoplasma fermentans

    Authors: Francesca Benedetti, Emmanuel F. Mongodin, Jonathan H. Badger, Arshi Munawwar, Ashley Cellini, Weirong Yuan, Giovannino Silvestri, Carl N. Kraus, Simone Marini, Chozha V. Rathinam, Marco Salemi, Hervé Tettelin, Robert C. Gallo and Davide Zella
    Citation: Journal of Translational Medicine 2024 22:269
  36. MicroRNAs (miRNAs) play a crucial role in gene expression and regulation, with dysregulation of miRNA function linked to various diseases, including hepatitis C virus (HCV)-related hepatocellular carcinoma (HC...

    Authors: Ciniso Sylvester Shabangu, Wen-Hsiu Su, Chia-Yang Li, Ming-Lung Yu, Chia-Yen Dai, Jee-Fu Huang, Wan-Long Chuang and Shu-Chi Wang
    Citation: Journal of Translational Medicine 2024 22:268
  37. Mitophagy, a prominent cellular homeostasis process, has been implicated in modulating endothelial cell function. Emerging evidence suggests that extracellular vesicles (EVs) participate in intercellular commu...

    Authors: Xiang Ying, Xiaocui Zheng, Xiaoqian Zhang, Yujia Yin and Xipeng Wang
    Citation: Journal of Translational Medicine 2024 22:267
  38. The clinical routine test of HBV-specific T cell reactivity is still limited due to the high polymorphisms of human leukocyte antigens (HLA) in patient cohort and the lack of universal detection kit, thus the ...

    Authors: Yandan Wu, Xiaotao Liu, Yuan Mao, Ruixue Ji, Lingzhi Xia, Zining Zhou, Yan Ding, Pinqing Li, Yu Zhao, Min Peng, Jie Qiu and Chuanlai Shen
    Citation: Journal of Translational Medicine 2024 22:266
  39. Identifying individuals with mild cognitive impairment (MCI) at risk of progressing to Alzheimer’s disease (AD) provides a unique opportunity for early interventions. Therefore, accurate and long-term predicti...

    Authors: Yifan Wang, Ruitian Gao, Ting Wei, Luke Johnston, Xin Yuan, Yue Zhang and Zhangsheng Yu
    Citation: Journal of Translational Medicine 2024 22:265
  40. Idiopathic Pulmonary Fibrosis (IPF) is a type of chronic interstitial pneumonia, often fatal, with elusive causes and a bleak prognosis. Its treatment options are limited and largely ineffective. Early detecti...

    Authors: Wenhua Gan, Wenwen Song, Yujuan Gao, Xuexue Zheng, Fengjuan Wang, Zirui Zhang, Ke Zen, Hongwei Liang and Xin Yan
    Citation: Journal of Translational Medicine 2024 22:264
  41. Angiopoietin-like protein 3 (ANGPTL3) is secreted by hepatocytes and inhibits lipoprotein lipase and endothelial lipase activity. Previous studies reported the correlation between plasma ANGPTL3 levels and hig...

    Authors: Longyan Yang, Yan Wang, Yongsong Xu, Kun Li, Ruili Yin, Lijie Zhang, Di Wang, Lingling Wei, Jianan Lang, Yanan Cheng, Lu Wang, Jing Ke and Dong Zhao
    Citation: Journal of Translational Medicine 2024 22:263
  42. The mitochondria and endoplasmic reticulum (ER) communicate via contact sites known as mitochondria associated membranes (MAMs). Many important cellular functions such as bioenergetics, mitophagy, apoptosis, a...

    Authors: Yi Li, Hua-bin Wang, Jin-long Cao, Wen-jun Zhang, Hai-long Wang, Chang-hong Xu, Kun-peng Li, Yi Liu, Ji-rong Wang, Hua-lan Ha, Sheng-jun Fu and Li Yang
    Citation: Journal of Translational Medicine 2024 22:261
  43. Amino acids (AAs) are one of the primary metabolic substrates for cardiac work. The correlation between AAs and both atrial fibrillation (AF) and aging has been documented. However, the relationship between AA...

    Authors: Yunying Huang, Qiuzhen Lin, Yong Zhou, Jiayi Zhu, Yingxu Ma, Keke Wu, Zuodong Ning, Zixi Zhang, Na Liu, Mohan Li, Yaozhong Liu, Tao Tu and Qiming Liu
    Citation: Journal of Translational Medicine 2024 22:259
  44. Neural Tube Defects (NTDs) are congenital malformations of the central nervous system resulting from the incomplete closure of the neural tube during early embryonic development. Neuroinflammation refers to th...

    Authors: Wenshuang Wang, Yanhong Ji, Zhexu Dong, Zheran Liu, Shuang Chen, Lei Dai, Xiaolan Su, Qingyuan Jiang and Hongxin Deng
    Citation: Journal of Translational Medicine 2024 22:257
  45. Children with cancer receiving chemotherapy commonly report a cluster of psychoneurological symptoms (PNS), including pain, fatigue, anxiety, depression, and cognitive dysfunction. The role of the gut microbio...

    Authors: Jinbing Bai, Ronald Eldridge, Madelyn Houser, Melissa Martin, Christie Powell, Kathryn S. Sutton, Hye In Noh, Yuhua Wu, Thomas Olson, Konstantinos T. Konstantinidis and Deborah W. Bruner
    Citation: Journal of Translational Medicine 2024 22:256
  46. Benign prostatic hyperplasia (BPH) is common in elder men. The current study aims to identify differentially expressed genes (DEGs) in hyperplastic prostate and to explore the role of Nik related kinase (NRK) ...

    Authors: Weixiang He, Zelin Tian, Bingchen Dong, Yitong Cao, Wei Hu, Peng Wu, Lei Yu, Xinhua Zhang and Shanshan Guo
    Citation: Journal of Translational Medicine 2024 22:255

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