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Emerging Therapeutics

Section edited by Gennaro Ciliberto

© Parilov / stock.adobe.comThe Emerging Therapeutics section is dedicated to the wave of emerging therapeutics arising from the intense research efforts and therapeutic breakthroughs based on recent scientific and technological developments. 

The section is interested in original papers, reviews and perspectives on the advancements in the field, including genetic vaccines, monoclonal antibodies, CAR-Ts, gene therapy with viral vectors, clinical applications of CRISPR/CAS9 gene editing, microbiota-modulating approaches, ‘omics approaches, emerging therapeutics from the development of new technologies for drug development, and discovery of new intervention targets and the possibility for new drug combinations.

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  1. DNA damage response plays critical roles in tumor pathogenesis and radiotherapy resistance. Protein phosphorylation is a critical mechanism in regulation of DNA damage response; however, the key mediators for ...

    Authors: Jia Liu, Jingyi Li, Zhao Sun, Yangmiao Duan, Fengqin Wang, Guangwei Wei and Jing-Hua Yang
    Citation: Journal of Translational Medicine 2021 19:339
    Content type: Research Published on:

  2. In recent years, long non-coding RNAs (lncRNAs) have attracted much attention because of its regulatory role in occurrence and progression of tumors, including triple-negative breast cancer (TNBC). LncRNA PITP...

    Authors: Bolong Liu, Pingbo Yao, Feng Xiao, Jianjin Guo, Lianghui Wu and Yong Yang
    Citation: Journal of Translational Medicine 2021 19:333
    Content type: Research Published on:

  3. Reversible enzymatic methylation of mammalian mRNA is widespread and serves crucial regulatory functions, but little is known to what degree chemical alkylators mediate overlapping modifications and whether ce...

    Authors: Kristian Lied Wollen, Lars Hagen, Cathrine B. Vågbø, Renana Rabe, Tobias S. Iveland, Per Arne Aas, Animesh Sharma, Bjørnar Sporsheim, Hilde O. Erlandsen, Vuk Palibrk, Magnar Bjørås, Davi M. Fonseca, Nima Mosammaparast and Geir Slupphaug
    Citation: Journal of Translational Medicine 2021 19:287
    Content type: Research Published on:

  4. Improved understanding of tumor immunology has enabled the development of therapies that harness the immune system and prevent immune escape. Numerous clinical trials and real-world experience has provided evi...

    Authors: Paolo A. Ascierto, Carlo Bifulco, Fortunato Ciardiello, Sandra Demaria, Leisha A. Emens, Robert Ferris, Silvia C. Formenti, Jerome Galon, Samir N. Khleif, Tomas Kirchhoff, Jennifer McQuade, Kunle Odunsi, Akash Patnaik, Chrystal M. Paulos, Janis M. Taube, John Timmerman…
    Citation: Journal of Translational Medicine 2021 19:238
    Content type: Meeting report Published on:

Journal of Translational Medicine

ISSN: 1479-5876

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