Volume 10 Supplement 3

7th European Workshop on Immune-Mediated Inflammatory Diseases

Meeting abstracts

Edited by Timothy Radstake, Leonie Taams and Ola Winqvist

Publication of this supplement has been supported by the conference.

7th European Workshop on Immune-Mediated Inflammatory Diseases. Go to conference site.

Noordwijk aan Zee, the Netherlands28-30 November 2012

Concatenated PDF 10S3

Page 1 of 2

Content type: Invited speaker presentation

Abstract not submitted for publication

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Citation: Journal of Translational Medicine 2012 10(Suppl 3):I1

Published on: 28 November 2012
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Citation: Journal of Translational Medicine 2012 10(Suppl 3):I2

Published on: 28 November 2012
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Lighting a candle in the dark: advances in the genetics and (gene) therapy of retinal dystrophies

Authors: Anneke I den Hollander

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I3

Published on: 28 November 2012
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Citation: Journal of Translational Medicine 2012 10(Suppl 3):I4

Published on: 28 November 2012
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Patient stratification and genomics: flares, fizzlers and foxes

Authors: Kenneth GC Smith

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I5

Published on: 28 November 2012
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Finding new immune regulatory genes by ENU mutagenesis

Authors: Anselm Enders, Hannes Bergmann, Mehmet Yabas, T Dan Andrews, Belinda Whittle, Mathew Field, Bhavani Balakishnan, Yovina Sontani, Lisa Miosge, Geoff Sjollema, Stuart Read, Ed Bertram and Chris C Goodnow

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I6

Published on: 28 November 2012
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Type 1 regulatory T (Tr1) cells: from the bench to the bedside

Authors: Silvia Gregori, Rosa Bacchetta, Manuela Battaglia and Maria Grazia Roncarolo

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I7

Published on: 28 November 2012
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What does it take to be healthy? Investigating immune-deficiency in non-immunodeficient scenarios

Authors: Elisa Binda, Reiner Schulz, Ania Showera, Andrew Cope, Michael Malim, John Cason, Mark Peakman and Adrian Hayday

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I8

Published on: 28 November 2012
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Intestinal immunity marches on its stomach

Authors: Marc Veldhoen

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I9

Published on: 28 November 2012
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Follicular lymphomagenesis: early steps and associated risk factors

Authors: Sandrine Roulland

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I10

Published on: 28 November 2012
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Citation: Journal of Translational Medicine 2012 10(Suppl 3):I11

Published on: 28 November 2012
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Type 1 diabetes - an auto-inflammatory disease: a new concept, new therapeutical strategies

Authors: Catarina Limbert

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I12

Published on: 28 November 2012
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Citation: Journal of Translational Medicine 2012 10(Suppl 3):I13

Published on: 28 November 2012
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Treg in CNS autoimmune disease

Authors: Stephen M Anderton

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I14

Published on: 28 November 2012
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IL-12 superfamily members guiding the function of Rorγt-dependent innate lymphocytes

Authors: Burkhard Becher

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I15

Published on: 28 November 2012
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Role of human innate lymphoid cells in IMID

Authors: Hergen Spits, Jochem Bernink, Charlotte Peters and Jenny Mjosberg

Citation: Journal of Translational Medicine 2012 10(Suppl 3):I16

Published on: 28 November 2012
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Content type: Oral presentation

NF-kappaB inducing kinase (NIK) is a key regulator of inflammation-induced angiogenesis

Authors: Ae-Ri Noort, Katinka PM van Zoest, Pieter Koolwijk, Paul-Peter Tak and Sander W Tas

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O1

Published on: 28 November 2012
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Graft versus host disease in humanized mice is differentially controlled by CD28 and CD80/86 antagonists

Authors: Nicolas Poirier, Nahzli Dilek, Caroline Mary and Bernard Vanhove

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O2

Published on: 28 November 2012
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Analysis of dendritic cells in human lymphoid organs

Authors: Gordon F Heidkamp, Nathalie Eissing, Lukas Heger, Robert Cesnjevar, Arndt Hartmann, Johannes Zenk, Evelyn Ulrich, Andreas Mackensen, Gerold Schuler, Burkhard Schauf, Falk Nimmerjahn and Diana Dudziak

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O3

Published on: 28 November 2012
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No lack of regulatory B cells in patients with Multiple Sclerosis

Authors: Laure Michel, Mélanie Chesneau, Philippe Manceau, Alexandra Garcia, Marion Salou, Annie Elong Ngono, Annaïck Pallier, Marylène Jacq-Foucher, Fabienne Lefrère, Sandrine Wiertlewski, Jean-Paul Soulillou, Nicolas Degauque, David-Axel Laplaud and Sophie Brouard

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O4

Published on: 28 November 2012
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Content type: Oral presentation

The role of Bob1 in rheumatoid arthritis: potential implications for autoimmunity

Authors: Nataliya Yeremenko, Tineke Cantaert, Melissa N van Tok, Ioana Gofita, Juan D Canete, Paul-Peter Tak, Hergen Spits and Dominique L Baeten

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O5

Published on: 28 November 2012
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Content type: Oral presentation

Role of Ras isoforms in γδ T-cell development

Authors: Ana V Marín-Marín, Eva Jiménez Pérez, Eugenio Santos and Edgar Fernández-Malavé

Citation: Journal of Translational Medicine 2012 10(Suppl 3):O6

Published on: 28 November 2012
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Content type: Poster presentation

Factor Xa and thrombin induce epithelial-mesenchymal transition by retinal pigment epithelial cells via PDGF-Rβ signaling

Authors: Jeroen Bastiaans, Jan C van Meurs, Conny van Holten-Neelen, Nicole MA Nagtzaam, P Martin van Hagen, Herbert Hooijkaas and Willem A Dik

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P1

Published on: 28 November 2012
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FcRn mediated IgG transport by retinal pigment epithelium cells

Authors: Nicoline M Korthagen, Kiki van Bilsen, Willem A Dik, Jeroen Bastiaans, Marion Kolijn, Robert W Kuijpers and Martin van Hagen

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P2

Published on: 28 November 2012
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Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4⁺CD45RO⁺CD25⁺CD127^low regulatory T cells

Authors: Gina J Walter, Hayley G Evans, Bina Menon, Bruce W Kirkham, Andrew P Cope, Frederic Geissmann and Leonie S Taams

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P3

Published on: 28 November 2012
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Human circulating basophils lack the features of professional antigen presenting cells

Authors: Meenu Sharma, Pushpa Hegde, Vishukumar Aimanianda, Jean-Paul Latgé, Srini V Kaveri and Jagadeesh Bayry

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P4

Published on: 28 November 2012
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Decreased AIRE and promiscuous gene expression in thymus from Down syndrome individuals may explain predisposition to autoimmunity

Authors: Roger Colobran, Maria del Pilar Armengol, Eduard Porta, Paula A Correa and Ricardo Pujol-Borrell

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P5

Published on: 28 November 2012
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Differential regulation of motility and immune synapses by CD28/ CTLA-4 costimulation in effector and regulatory T cells

Authors: Nahzli Dilek, Nicolas Poirier, Philippe Hulin, Gilles Blancho and Bernard Vanhove

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P6

Published on: 28 November 2012
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Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps–SHP-2 pathway

Authors: Sheng Xu, Jin Hou, Xingguang Liu, Chaofeng Han, Peng Zhang and Xuetao Cao

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P7

Published on: 28 November 2012
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Distal renal tubular acidosis in primary Sjögren syndrome

Authors: Tim Both, Ewout J Hoorn, Zana Brkic, Marjan A Versnel, Jan AM van Laar, P Martin van Hagen, Robert Zietse and Paul LA van Daele

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P8

Published on: 28 November 2012
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Dynamics of CXC group chemokine platelet factor 4 (PF4) plasma levels in non-small cell lung cancer (NSCLC)

Authors: Artjoms Spaks, Inta Jaunalksne, Simona Donina, Ainis Pirtnieks, Jelena Grusina-Ujumaza, Irina Spaka, Aurika Babjoniseva and Dainis Krievins

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P9

Published on: 28 November 2012
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Basophil Activation Test in the prediction of anaphylactic reactions against Hymenoptera venom in patients suffering from Systemic Mastocytosis

Authors: Mark JA Rietveld, Marco WJ Schreurs, Jan AM van Laar, P Martin van Hagen and Paul LA van Daele

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P10

Published on: 28 November 2012
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A case report of a lichenoid eruption in a young lady with Crohn’s disease

Authors: Farida Benhadou and Véronique Del Marmol

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P11

Published on: 28 November 2012
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Dietary management of inflammatory diseases

Authors: Umar Bacha, Muhammad A Ali, Abdul Basit and Uzma Litaf

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P12

Published on: 28 November 2012
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Peripheral blood leukocytes express differential chemokine receptor profiles in irritable bowel syndrome, Crohn’s disease and ulcerative colitis

Authors: Ludvig Linton, Emma Lindh, Hans Glise, Michael Eberhardson and Ola Winqvist

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P13

Published on: 28 November 2012
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IL-17 as an important effector cytokine in a mouse model for S.typhimurium sepsis

Authors: Andrea Schroll, Manfred Nairz, Igor Theurl and Günther Weiss

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P14

Published on: 28 November 2012
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Molecular factors modulating the anti-inflammatory activity of IVIg in ITP

Authors: Inessa Schwab and Falk Nimmerjahn

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P15

Published on: 28 November 2012
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Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway

Authors: Patricia Luz-Crawford, Daniele Noël, Fernando Figueroa, Flavio Carrión, Christian Jorgensen and Farida Djouad

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P16

Published on: 28 November 2012
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Antagonist properties of monoclonal antibodies to human CD28: role of valency and heavy-chain constant domain

Authors: Caroline Mary, Flora Coulon, Nicolas Poirier, Nahzli Dilek, Bernard Martinet, Gilles Blancho and Bernard Vanhove

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P17

Published on: 28 November 2012
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Lymphocytes subset composition and modulation of sphingosie-1-phosphate mediated migration in multiple sclerosis patients treated with fingolimod or interferon-β

Authors: Heiko Sic, Michael Stock, Sebastian Rauer and Hermann Eibel

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P18

Published on: 28 November 2012
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SOCS2 expression in bone marrow derived dendritic cells is a positive regulator of T cell activation

Authors: Jin Hu, Berit Carow, Ann-Charlotte Wikström, Martin Rottenberg, Gunnar Norstedt and Ola Winqvist

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P19

Published on: 28 November 2012
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Altered innate functions of myeloid dendritic cells in ANCA-associated vasculitis

Authors: Cécile Braudeau, Antoine Néel, Marie Rimbert, Mohamed Hamidou and Régis Josien

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P20

Published on: 28 November 2012
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Vascular endothelial growth factor genetic polymorphisms and susceptibility to age-related macular degeneration in Tunisian population

Authors: Imen Habibi, Imen Sfar, Fedra Kort, Ahmed Chebil, Rim Bouraoui, Rim Limaiem, Salwa Jendoubi-Ayed, Mouna Makhlouf, Taïeb Ben Abdallah, Khaled Ayed, Leila El Matri and Yousr Gorgi

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P21

Published on: 28 November 2012
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Macrophage-fibroblast interplay: a target for neuropeptide-based treatment of fibrotic disease?

Authors: Sita Virakul, Willem A Dik, Leo J Hofland, P Martin van Hagen and Virgil ASH Dalm

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P22

Published on: 28 November 2012
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PIM2 induced MMP-9 expression in macrophages requires PI3K and Notch1 signaling

Authors: Nisha Kapoor, Kushagra Bansal, Germain Puzo, Martine Gilleron and KN Balaji

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P23

Published on: 28 November 2012
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Influence of activating Fcgamma receptors on osteoclast differentiation and bone metabolism

Authors: Michaela Seeling, Jan Peter Tuckermann, Jean Pierre David, Georg Schett and Falk Nimmerjahn

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P24

Published on: 28 November 2012
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Deficiency of regulatory B cells in a house dust mite model of asthma

Authors: Faouzi Braza, Julie Chesné, G Mahay, MA Cheminant, D Lair, K Botturi-Cavaillès, Antoine Magnan and Sophie Brouard

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P25

Published on: 28 November 2012
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Characterization of murine experimental autoimmune encephalomyelitis induced by active immunization with a CD8 epitope of myelin oligodendrocyte glycoprotein

Authors: Flora Guillot, Sophie Brouard, David A Laplaud and Arnaud B Nicot

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P26

Published on: 28 November 2012
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Tolerogenic dendritic cells in experimental autoimmune encephalomyelitis, specific tolerance induction?

Authors: Carla Sellés-Moreno, Cristina Ramo-Tello, Laia Grau-López, Ricardo Pujol-Borrel and Eva M Martínez-Cáceres

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P27

Published on: 28 November 2012
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The reason to stop infliximab is clearly related to the existence of new alternatives: a correspondence analysis of biologics, reasons to stop, and time periods

Authors: Julia Uceda, Loreto Carmona, Alejandro Muñoz and Jose L Marenco

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P28

Published on: 28 November 2012
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7th European Workshop on Immune-Mediated Inflammatory Diseases

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