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CD4+CD45RA+ T-cells from early diffuse systemic sclerosis patients produce high levels of interleukin-17

Authors: Lenny van Bon, Marta Cossu, Wim van den Berg, Madelon Vonk, Hans Koenen and Timothy Radstake

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P62

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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The expression of CXCR4/CXCL12 determines subsets of patients in systemic lupus erythematosus

Authors: Philippe Guilpain, Andrew Wang, Benjamin F Chong, Sandrine Chouzenoux, Loic Guillevin, Xin J Zhou, Fangming Lin, Anna-Marie Fairhurst, Christopher Boudreaux, Christian Roux, Edward K Wakeland, Laurie Davis, Frederic Batteux and Chandra Mohan

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P60

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis

Authors: Mark H Wenink, Kim CM Santegoets, John Butcher, Lenny van Bon, Femke GM Lamers-Karnebeek, Wim B van den Berg, Piet LCM van Riel, Iain B McInnes and Timothy RDJ Radstake

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P58

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Osteoclasts modulate the balance between immunosuppression and inflammation through antigen presentation and interactions with CD4⁺ T cells

Authors: Grazia Abou Ezzi, Thomas Ciucci, Vanessa Amiot, Abdelilah Wakkach and Claudine Blin-Wakkach

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P56

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Apolipoprotein E and undercaboxylated osteocalcin are associated with bone fragility but not with bone mineral density in osteoarthritis patients

Authors: Ana Rodrigues, Joana Caetano-Lopes, Ana Lopes, Ana C Vale, Inês Aleixo, Inês P Perpétuo, Ana S Pena, Alexandra Faustino, Alexandre Sepriano, Joaquim Polido-Pereira, Elsa Vieira-Sousa, Bruno Vidal, José C Romeu, Pedro M Amaral, Luís G Rosa, José A Pereira da Silva…

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P54

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Characterization of patients with anti-modified citrullinated vimentin antibodies (MCVA)

Authors: Estíbaliz Ruiz-Ortiz de Arrizabaleta, Dolors Grados-Cánovas, Aina Teniente-Serra, Iñaki Salvador-Corres, Ana Marín, Melania Martínez-Morillo, Susana Holgado, Alejandro Olivé, Ricardo Pujol-Borrell and Eva Martínez-Cáceres

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P52

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Non-canonical NF-κB signaling in endothelial cells may enhance synovial inflammation by stimulating angiogenesis

Authors: Ae-Ri Noort, Katinka PM van Zoest, Paul Peter Tak and Sander W Tas

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P50

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Unique circulating cytokine profile of rheumatoid arthritis patients with nodules

Authors: Bridget Hodkinson, Pieter WA Meyer, Eustatius Musenge, Mahmood Ally, Ronlad Anderson and Mohammed Tikly

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P48

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Clinical and functional effectiveness of anti-TNF therapy in patients with rheumatoid arthritis

Authors: Rosalia Martínez-Pérez, Julia Uceda, Mario León, Sergio Rodríguez, Alejandro Muñoz, Francisco Gallo, Maria Luisa Velloso and Jose Luis Marenco

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P46

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Effectiveness of dose reduction of etanercept and adalimumab in patients with rheumatoid arthritis

Authors: Rosalía Martínez-Pérez, Sergio Rodríguez-Montero, Alejandro Muñoz, Julia Uceda, Mario León, Francisco Gallo, Maria Luisa Velloso and José Luis Marenco

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P44

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Therapeutic responses and prognosis in Korean adult-onset Still’s disease

Authors: Hyoun-Ah Kim, Jeong-Mi An and Chang-Hee Suh

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P35

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Synovial lymphoid neogenesis is associated with IL-23 expression and disease activity in rheumatoid arthritis

Authors: Juan D Cañete, Raquel Celis, Julio Ramírez, Sara Marsal, Gabriela Ávila, Raimón Sanmartí and José L Pablos

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P33

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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PD1/PD-L1 dependent immunosuppression by huiPS-derived cell population

Authors: Jonathan Pini, Arieh Moussaieff, Emilie Murris, Reuven Shalom-Feuerstein, Isabelle Petit, Daniel Aberdam and Matthieu Rouleau

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P31

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Alloantigenic recognition properties of CD8⁺ regulatory T cells

Authors: Elodie Picarda, Ignacio Anegon and Carole Guillonneau

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P29

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Tranilast, an analogue of tryptophan catabolites, induces allograft tolerance by CD161⁺ cells

Authors: Séverine Ménoret, Séverine Bézie, Xian-Liang Li, Claire Usal, Lise Caron and Ignacio Anegon

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P27

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Loss of IL-10 secretion by regulatory B lymphocytes in multiple sclerosis patients

Authors: Laure Michel, Nicolas Degauque, Alexandra Garcia, Marion Salou, Annie Elong Ngono, Jean-Paul Soulillou, David Laplaud and Sophie Brouard

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P25

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Regulation of chemokine and chemokine receptor expression by PPARG in adipocytes and macrophages

Authors: MT Audrey Nguyen, Ai Chen, Wendell J Lu, WuQiang Fan, Ping-Ping Li, Dayoung Oh and David Patsouris

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P23

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Drugs that simultaneously down-regulate IL-1β and TNF secretion significantly reduce inflammation in a rat model of antigen-induced arthritis

Authors: Rita Cascão, Bruno Vidal, Helena Raquel, Vineet Gupta, João E Fonseca and Luis F Moita

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P21

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Longitudinal immunomonitoring following Tocilizumab in rheumatoid arthritis

Authors: Yves-Marie Pers, Pascale Louis-Plence, Pierre Portales, Julie Quentin, Sylvie Fabre, Jean-François Eliaou and Christian Jorgensen

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P19

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Immunostimulatory effects on B cells by the chemotherapeutic drug Doxorubicin

Authors: Johan M Kinn, Ali Zirakzadeh, Jin Hu and Ola Winqvist

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P17

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Regulatory T cells for the control of physiological and pathological immune responses

Authors: Shimon Sakaguchi

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I16

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Treatment of lupus erythematosus with fumaric acid ester derivatives: two case-reports

Authors: Deepak MW Balak and H Bing Thio

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P15

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Breakdown of antimicrobial host defense barrier as trigger of chronic inflammatory bowel diseases

Authors: Jan Wehkamp

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I14

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Synthesis and characterization of non-viral liposomal carriers for the local application of siRNA molecules and anti-miRNAs in the therapeutic treatment of psoriasis

Authors: Stefanie Bracke, Barbara Geusens, Peter Dynoodt, Mireille Van Gele, Reinhart Speeckaert, Joost Schalkwijk, Sandra Tjabringa and Jo Lambert

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P13

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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IL-10 secreting regulatory B cells are potent arbiters of autoimmunity in both mouse and man

Authors: Claudia Mauri, Fabian Flores-Borja, Paul A Blair and Natalie A Carter

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I12

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Differential regulation of IL-22BP in Crohn’s disease versus ulcerative colitis

Authors: Jérôme Martin, Céline Bossard, Arnaud Boureille and Régis Josien

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P11

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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NOD2 function in Crohn's disease

Authors: Alison Simmons

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I10

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Therapeutic inhibition of proteasomes in systemic lupus erythematosus

Authors: Falk Hiepe, Bimba Hoyer, Tobias Alexander, Adriano Taddeo, Reinhard Voll and Andreas Radbruch

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I9

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Somatostatin receptor scintigraphy in sarcoidosis

Authors: Lieke SJ Kamphuis, Dik J Kwekkeboom, Jan AM van Laar, Paul LA van Daele, G Seerp Baarsma and P Martin van Hagen

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P9

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Immune-mediated muscle wasting and cell survival - the tale of a curious gene

Authors: James A Ross

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I8

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Biological ageing is a key determinant in systemic sclerosis

Authors: Paul G Shiels, JCA Broen, LM McGlynn, J Thomson, MM Chee, R Madhok and TRDJ Radstake

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I7

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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A SNP in intron 1 of TSHR controls its thymic expression and susceptibility to Graves’ disease suggesting central tolerance failure in pathogenesis

Authors: Maria del Pilar Armengol, Rosa Faner, Lars-Olivier Tykocinski, Anna Lucas-Martin, Marta Ruiz-Riol, Manel Juan, Bruno Kyewski, Ricardo Pujol-Borrell and Roger Colobran

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P7

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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The anti-microbial peptide rCRAMP is strongly upregulated during experimental arthritis in the rat

Authors: Markus H Hoffmann, Martin Herrmann, Birgitta Agerberth and Rikard Holmdahl

Citation: Journal of Translational Medicine 2011 9(Suppl 2):O7

Content type: Oral presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Omenn Syndrome: inflammation and autoimmunity

Authors: Anna Villa

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I5

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

Authors: Stefan Uderhardt, Martin Herrmann, Olga Oskolkova, Reinhard Voll, Falk Nimmerjahn, Valery Bochkov, Georg Schett and Gerhard Kroenke

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P5

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Immunosuppressive role of fibrinogen-like protein 2 (FGL2) in CD8⁺regulatory T cells-mediated long-term graft survival

Authors: Séverine Bézie, Séverine Ménoret, Laurent Tesson, Xian-Liang Li, Claire Usal, Ignacio Anegon and Lise Caron

Citation: Journal of Translational Medicine 2011 9(Suppl 2):O5

Content type: Oral presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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A rare polymorphism in Toll Like Receptor 2 is associated with systemic sclerosis phenotype and increases production of inflammatory mediators

Authors: Jasper CA Broen, Lara Bossini-Castillo, Lenny van Bon, Madelon C Vonk, Hanneke Knaapen, Lorenzo Beretta, Blanca Rueda, Roger Hesselstrand, Ariane Herrick, Jane Worthington, Nicholas Hunzelmann, Christopher Denton, Carmen Fonseca, Gabriela Riemekasten, Hans Kiener, Raffaella Scorza…

Citation: Journal of Translational Medicine 2011 9(Suppl 2):O4

Content type: Oral presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Epigenetic alterations in autoimmune disease

Authors: Esteban Ballestar, Biola M Javierre, Lorenzo de la Rica, David Gómez-Cabrero, Jesper Tegnér, Carmen Gomez-Vaquero, Javier Narvaez, Henar Hernando, Virginia C Rodriguez, Roser Vento, Laura Ciudad and Javier Rodriguez-Ubreva

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I3

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung

Authors: Nicolas Glaichenhaus, Cyrille Mionnet and Valérie Julia

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P3

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Reverse signalling of membrane TNF in human natural killer cells: a comparison of the effect of certolizumab pegol and other anti-TNF agents

Authors: Gianluca Fossati and Andrew M Nesbitt

Citation: Journal of Translational Medicine 2011 9(Suppl 2):O3

Content type: Oral presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Coeliac disease: the showcase of interaction between genes, environment and immunology in chronic tissue inflammation

Authors: Ludvig M Sollid

Citation: Journal of Translational Medicine 2011 9(Suppl 2):I1

Content type: Invited lecture presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10

Authors: Carmen Ambarus, Lenny Geurts-van Bon, Mark Wenink, Paul Peter Tak, Timothy Radstake and Dominique Baeten

Citation: Journal of Translational Medicine 2011 9(Suppl 2):P1

Content type: Poster presentation Published on: 23 November 2011

This article is part of a Supplement: Volume 9 Supplement 2
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Calcium-sensing receptor and calcium kidney stones

Calcium nephrolithiasis may be considered as a complex disease having multiple pathogenetic mechanisms and characterized by various clinical manifestations. Both genetic and environmental factors may increase ...

Authors: Giuseppe Vezzoli, Annalisa Terranegra, Francesco Rainone, Teresa Arcidiacono, Mario Cozzolino, Andrea Aloia, Elena Dogliotti, Daniele Cusi and Laura Soldati

Citation: Journal of Translational Medicine 2011 9:201

Content type: Review Published on: 22 November 2011
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The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of ca...

Authors: Andrej Valkov, Thomas K Kilvaer, Sveinung W Sorbye, Tom Donnem, Eivind Smeland, Roy M Bremnes and Lill-Tove Busund

Citation: Journal of Translational Medicine 2011 9:200

Content type: Research Published on: 22 November 2011
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How scientists use social media to communicate their research

Millions of people all over the world are constantly sharing an extremely wide range of fascinating, quirky, funny, irrelevant and important content all at once. Even scientists are no strangers to this trend....

Authors: Laura Van Eperen and Francesco M Marincola

Citation: Journal of Translational Medicine 2011 9:199

Content type: Editorial Published on: 15 November 2011
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Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate

Dendritic cells (DCs) are the most potent antigen-presenting cell population for activating tumor-specific T cells. Due to the wide range of methods for generating DCs, there is no common protocol or defined s...

Authors: Cheryl L-L Chiang, Dawn A Maier, Lana E Kandalaft, Andrea L Brennan, Evripidis Lanitis, Qunrui Ye, Bruce L Levine, Brian J Czerniecki, Daniel J Powell Jr and George Coukos

Citation: Journal of Translational Medicine 2011 9:198

Content type: Research Published on: 14 November 2011
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Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms

MicroRNA (miR) miR-34 a, -34b/c, -124-1 and -203 are tumor suppressor miRs implicated in carcinogenesis.

Authors: Chor Sang Chim, Thomas S Wan, Kwan Yeung Wong, Tsz Kin Fung, Hans G Drexler and Kit Fai Wong

Citation: Journal of Translational Medicine 2011 9:197

Content type: Research Published on: 14 November 2011
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Anti-CTLA4 monoclonal antibodies: the past and the future in clinical application

Recently, two studies using ipilimumab, an anti-CTLA-4 monoclonal antibody (mab) demonstrated improvements in overall survival in the treatment of advanced melanoma. These studies utilized two different schedu...

Authors: Paolo A Ascierto, Francesco M Marincola and Antoni Ribas

Citation: Journal of Translational Medicine 2011 9:196

Content type: Commentary Published on: 13 November 2011
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Inhibition of HCV 3a genotype entry through Host CD81 and HCV E2 antibodies

HCV causes acute and chronic hepatitis which can eventually lead to permanent liver damage hepatocellular carcinoma and death. HCV glycoproteins play an important role in HCV entry by binding with CD81 recepto...

Authors: Usman A Ashfaq, Muhammad Qasim, Muhammad Z Yousaf, Muhammad Tariq Awan and Shah Jahan

Citation: Journal of Translational Medicine 2011 9:194

Content type: Research Published on: 10 November 2011
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Elevated levels of Dickkopf-related protein 3 in seminal plasma of prostate cancer patients

Expression of Dkk-3, a secreted putative tumor suppressor, is altered in age-related proliferative disorders of the human prostate. We now investigated the suitability of Dkk-3 as a diagnostic biomarker for pr...

Authors: Christoph Zenzmaier, Martin Heitz, Helmut Klocker, Marion Buck, Robert A Gardiner and Peter Berger

Citation: Journal of Translational Medicine 2011 9:193

Content type: Research Published on: 10 November 2011
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