Skip to main content


Page 109 of 126

  1. Human papilloma virus (HPV)-16 is the most prevalent high-risk mucosal genotype. Virus-like-particle (VLP)-based immunogens developed recently have proven to be successful as prophylactic HPV vaccines, but are...

    Authors: Carlo Zanotto, Eleana Pozzi, Sole Pacchioni, Massimiliano Bissa, Carlo De Giuli Morghen and Antonia Radaelli
    Citation: Journal of Translational Medicine 2011 9:190
  2. In the last years human proteomic has represented a promising tool to promote the communication between basic and clinical science.

    Authors: Chiara Baldini, Laura Giusti, Federica Ciregia, Ylenia Da Valle, Camillo Giacomelli, Elena Donadio, Francesco Ferro, Sara Galimberti, Valentina Donati, Laura Bazzichi, Stefano Bombardieri and Antonio Lucacchini
    Citation: Journal of Translational Medicine 2011 9:188
  3. Erythropoietin (EPO) is a glycoprotein hormone which is required to regulate the production of red blood cells. Deficiency of EPO is known to cause anemia in chronically infected renal patients and they requir...

    Authors: Humera Kausar, Sana Gull, Bushra Ijaz, Waqar Ahmad, Muhammad Tahir Sarwar, Zafar Iqbal, Zafar Nawaz, Sheikh Riazuddin and Sajida Hassan
    Citation: Journal of Translational Medicine 2011 9:186
  4. Prostate cancer metastasizes to bone in the majority of patients with advanced disease leading to painfully debilitating fractures, spinal compression and rapid decline. In addition, prostate cancer bone metas...

    Authors: Omer Raheem, Anna A Kulidjian, Christina Wu, Young B Jeong, Tomonori Yamaguchi, Kristen M Smith, Daniel Goff, Heather Leu, Sheldon R Morris, Nicholas A Cacalano, Koichi Masuda, Catriona HM Jamieson, Christopher J Kane and Christina AM Jamieson
    Citation: Journal of Translational Medicine 2011 9:185
  5. Human Leukocyte Antigen (HLA)-E is a non-classical class I HLA molecule that can be stabilized by ligands donated by other classical (HLA-A, -B, -C) and non-classical (HLA-G) family members. HLA-E engages a va...

    Authors: Maria Benevolo, Marcella Mottolese, Elisa Tremante, Francesca Rollo, Maria Grazia Diodoro, Cristiana Ercolani, Isabella Sperduti, Elisa Lo Monaco, Maurizio Cosimelli and Patrizio Giacomini
    Citation: Journal of Translational Medicine 2011 9:184
  6. Chronic refractory angina is a challenging clinical problem with limited treatment options. The results of early cardiovascular stem cell trials using ABMMC have been promising but have utilized intracoronary ...

    Authors: Jorge Tuma, Roberto Fernández-Viña, Antonio Carrasco, Jorge Castillo, Carlos Cruz, Alvaro Carrillo, Jose Ercilla, Carlos Yarleque, Jaime Cunza, Timothy D Henry and Amit N Patel
    Citation: Journal of Translational Medicine 2011 9:183
  7. Idiopathic pulmonary fibrosis represents a lethal form of progressive fibrotic lung disorder with gradually increasing incidence worldwide. Despite intense research efforts its pathogenesis is still elusive an...

    Authors: Argyris Tzouvelekis, George Koliakos, Paschalis Ntolios, Irene Baira, Evangelos Bouros, Anastasia Oikonomou, Athanassios Zissimopoulos, George Kolios, Despoina Kakagia, Vassilis Paspaliaris, Ioannis Kotsianidis, Marios Froudarakis and Demosthenes Bouros
    Citation: Journal of Translational Medicine 2011 9:182
  8. Prolonged life expectancy, life style and environmental changes have caused a changing disease pattern in developed countries towards an increase of degenerative and autoimmune diseases. Stem cells have become...

    Authors: Jeong Chan Ra, Sung Keun Kang, Il Seob Shin, Hyeong Geun Park, Sang Aun Joo, Jeong Geun Kim, Byeong-Cheol Kang, Yong Soon Lee, Ken Nakama, Min Piao, Bertram Sohl and Andras Kurtz
    Citation: Journal of Translational Medicine 2011 9:181
  9. Accumulating evidence supports the role of the mineralocorticoid receptor (MR) in the pathogenesis of diabetic nephropathy. These findings have generated renewed interest in novel MR antagonists with improved ...

    Authors: Rena J Eudy, Vaishali Sahasrabudhe, Kevin Sweeney, Meera Tugnait, Amanda King-Ahmad, Kristen Near, Paula Loria, Mary Ellen Banker, David W Piotrowski and Carine M Boustany-Kari
    Citation: Journal of Translational Medicine 2011 9:180
  10. Cancer patients receiving chemotherapy are at increased risk of thrombosis. Nadroparin has been demonstrated to reduce the incidence of venous and arterial thrombotic events (TEs) by about 50% in cancer outpat...

    Authors: Sandro Barni, Roberto Labianca, Giancarlo Agnelli, Erminio Bonizzoni, Melina Verso, Mario Mandalà, Matteo Brighenti, Fausto Petrelli, Carlo Bianchini, Tania Perrone and Giampietro Gasparini
    Citation: Journal of Translational Medicine 2011 9:179
  11. Ten cancer patients (Six renal cell carcinoma and four breast cancer patients) were treated in a phase I/II study with a vaccine composed of autologous dendritic cells (DCs) and IL-2 to evaluate the DC vaccine...

    Authors: Soyoung Baek, Choung-Soo Kim, Sung-Bae Kim, Yong-man Kim, Seog-Woon Kwon, YongMan Kim, HyunSoo Kim and Hyunah Lee
    Citation: Journal of Translational Medicine 2011 9:178
  12. Tumour cells communicate with the cells of their microenvironment via a series of molecular and cellular interactions to aid their progression to a malignant state and ultimately their metastatic spread. Of th...

    Authors: Thea L Rogers and Ingunn Holen
    Citation: Journal of Translational Medicine 2011 9:177
  13. Fenofibrate, a PPAR alpha agonist, has been widely used in clinics as lipid-regulating agent. PPAR alpha is known to be expressed in many organs including pancreatic beta cells and regulate genes involved in f...

    Authors: Shuai-nan Liu, Quan Liu, Lin-yi Li, Yi Huan, Su-juan Sun and Zhu-fang Shen
    Citation: Journal of Translational Medicine 2011 9:176
  14. Heat shock protein 70 (HSP70) has gained major attention as an adjuvant capable of inducing antigen-specific CD8+ and CD4+ T-cell responses. The ability of HSP70/peptide complexes to elicit cytotoxic T-cell (CTL)...

    Authors: Sabine Tischer, Megan Basila, Britta Maecker-Kolhoff, Stephan Immenschuh, Mathias Oelke, Rainer Blasczyk and Britta Eiz-Vesper
    Citation: Journal of Translational Medicine 2011 9:175
  15. In humans, the role and relationship between molecular pathways that lead to tissue destruction during acute allograft rejection are not fully understood. Based on studies conducted in humans, we recently hypo...

    Authors: Tara L Spivey, Lorenzo Uccellini, Maria Libera Ascierto, Gabriele Zoppoli, Valeria De Giorgi, Lucia Gemma Delogu, Alyson M Engle, Jaime M Thomas, Ena Wang, Francesco M Marincola and Davide Bedognetti
    Citation: Journal of Translational Medicine 2011 9:174
  16. Oncolytic viral tumor therapy is an emerging field in the fight against cancer with rising numbers of clinical trials and the first clinically approved product (Adenovirus for the treatment of Head and Neck Ca...

    Authors: Michael Hess, Jochen Stritzker, Barbara Härtl, Julia B Sturm, Ivaylo Gentschev and Aladar A Szalay
    Citation: Journal of Translational Medicine 2011 9:172
  17. Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with multiple genetic aberrations. Several molecular pathways involved in the regulation of proliferation and cell death are implicated in th...

    Authors: Monica Marra, Ignazio M Sordelli, Angela Lombardi, Monica Lamberti, Luciano Tarantino, Aldo Giudice, Paola Stiuso, Alberto Abbruzzese, Rossella Sperlongano, Marina Accardo, Massimo Agresti, Michele Caraglia and Pasquale Sperlongano
    Citation: Journal of Translational Medicine 2011 9:171
  18. Over 90% of low risk (LR) neuroblastoma patients survive whereas less than 30% of high risk (HR) patients are long term survivors. Age (children younger than 18 months old) is associated with LR disease. Consi...

    Authors: Madhu Gowda, Kamar Godder, Maciej Kmieciak, Andrea Worschech, Maria-Libera Ascierto, Ena Wang, Francesco M Marincola and Masoud H Manjili
    Citation: Journal of Translational Medicine 2011 9:170
  19. Inhibition of the renin-angiotensin-aldosterone system (RAAS) slows down the progression of chronic renal diseases (CKD) including IgA nephropathy (IgAN). Herein, we studied the pathogenetic roles of aldostero...

    Authors: Joseph CK Leung, Loretta YY Chan, Sydney CW Tang, Man-Fai Lam, Chui-Wa Chow, Ai-Ing Lim and Kar-Neng Lai
    Citation: Journal of Translational Medicine 2011 9:169
  20. In head and neck squamous cell carcinoma (HNSCC), expression levels of the epidermal growth factor receptor (EGFR) correlate with poor prognosis and decreased survival rates. As the mechanisms responsible for ...

    Authors: Patrick J Schuler, Petra Boeckers, Rainer Engers, Edwin Boelke, Murat Bas, Jens Greve, Claudia A Dumitru, Goetz F Lehnerdt, Robert L Ferris, Pedro A Andrade Filho, Sven Brandau, Stephan Lang, Theresa L Whiteside and Thomas K Hoffmann
    Citation: Journal of Translational Medicine 2011 9:168
  21. Mutations in SLC26A4 cause Pendred syndrome (hearing loss with goiter) or DFNB4 (non-syndromic hearing loss with inner ear malformation, such as enlarged vestibular aqueduct or Mondini deformity). The relationshi...

    Authors: Shasha Huang, Dongyi Han, Yongyi Yuan, Guojian Wang, Dongyang Kang, Xin Zhang, Xiaofei Yan, Xiaoxiao Meng, Min Dong and Pu Dai
    Citation: Journal of Translational Medicine 2011 9:167
  22. Metastasis-associated in colon cancer-1 (MACC1) is a newly identified gene that plays a role in colon cancer metastasis through upregulation of c-MET proto-oncogene (c-MET). However, the value of MACC1 as a poten...

    Authors: Jiliang Qiu, Pinzhu Huang, Qian Liu, Jian Hong, Binkui Li, Canliang Lu, Li Wang, Jianping Wang and Yunfei Yuan
    Citation: Journal of Translational Medicine 2011 9:166
  23. Autologous bone marrow-derived stem cells have been ascribed an important therapeutic role in No-Option Critical limb Ischemia (NO-CLI). One primary endpoint for evaluating NO-CLI therapy is major amputation (...

    Authors: Eric Benoit, Thomas F O'Donnell Jr, Mark D Iafrati, Enrico Asher, Dennis F Bandyk, John W Hallett, Alan B Lumsden, Gregory J Pearl, Sean P Roddy, Krishnaswami Vijayaraghavan and Amit N Patel
    Citation: Journal of Translational Medicine 2011 9:165
  24. We have shown that insertion of the three vaccinia virus (VACV) promoter-driven foreign gene expression cassettes encoding Renilla luciferase-Aequorea GFP fusion protein, β-galactosidase, and β-glucuronidase into...

    Authors: Nanhai G Chen, Yong A Yu, Qian Zhang and Aladar A Szalay
    Citation: Journal of Translational Medicine 2011 9:164
  25. Metastatic non-small-cell lung cancer (NSCLC) has a dismal prognosis. EGFR is overexpressed or mutated in a large proportion of cases. Downstream components of the EGFR pathway and crosstalk with the NF-κB pat...

    Authors: Mariacarmela Santarpia, Ignacio Magri, Maria Sanchez-Ronco, Carlota Costa, Miguel Angel Molina-Vila, Ana Gimenez-Capitan, Jordi Bertran-Alamillo, Clara Mayo, Susana Benlloch, Santiago Viteri, Amaya Gasco, Nuria Mederos, Enric Carcereny, Miquel Taron and Rafael Rosell
    Citation: Journal of Translational Medicine 2011 9:163
  26. Chronic inflammation has been suggested to favour prostate cancer (PCA) development. Interleukins (IL) represent essential inflammation mediators. IL-2, IL-7, IL-15 and IL-21, sharing a common receptor γ chain...

    Authors: Chantal Mengus, Clémentine Le Magnen, Emanuele Trella, Kawa Yousef, Lukas Bubendorf, Maurizio Provenzano, Alexander Bachmann, Michael Heberer, Giulio C Spagnoli and Stephen Wyler
    Citation: Journal of Translational Medicine 2011 9:162
  27. Autophagy is a dynamic catabolic process characterized by the formation of double membrane vacuoles termed autophagosomes. LC3, a homologue of yeast Atg8, takes part in autophagosome formation, but the exact r...

    Authors: Ting Sun, DanDan Li, LinLin Wang, LiangPing Xia, JianGuo Ma, Zhong Guan, GongKan Feng and XiaoFeng Zhu
    Citation: Journal of Translational Medicine 2011 9:161
  28. The asymptomatic phase of HIV-1 infection is characterized by a progressive depletion of uninfected peripheral effector/memory CD4+ T cells that subsequently leads to immune dysfunction and AIDS symptoms. We h...

    Authors: Antigone K Morou, Filippos Porichis, Elias Krambovitis, George Sourvinos, Demetrios A Spandidos and Alexandros Zafiropoulos
    Citation: Journal of Translational Medicine 2011 9:160
  29. Acute pulmonary embolism (APE) remains a diagnostic challenge due to a variable clinical presentation and the lack of a reliable screening tool. MicroRNAs (miRNAs) regulate gene expression in a wide range of p...

    Authors: Junjie Xiao, Zhi-Cheng Jing, Patrick T Ellinor, Dandan Liang, Hong Zhang, Ying Liu, Xiaoli Chen, Lei Pan, Robert Lyon, Yi Liu, Lu-Ying Peng, Xingqun Liang, Yunfu Sun, Laurentiu M Popescu, Gianluigi Condorelli and Yi-Han Chen
    Citation: Journal of Translational Medicine 2011 9:159
  30. Gastrointestinal stromal tumors (GISTs) are the most frequent mesenchymal tumors to develop in the digestive tract. These tumors are highly resistant to conventional chemotherapy and only the introduction of i...

    Authors: Luca Da Riva, Fabio Bozzi, Piera Mondellini, Francesca Miccichè, Elena Fumagalli, Elena Vaghi, Eva Tarantino, Veronica Huber, Alessandro Gronchi, Elena Tamborini, Marco A Pierotti, Silvana Pilotti and Italia Bongarzone
    Citation: Journal of Translational Medicine 2011 9:158
  31. Treatment failure for esophageal carcinoma is frequently due to lymph node metastasis and invasion to neighboring organs. The aim of the present study was to investigate invasion- and metastasis-related genes ...

    Authors: Jian Pan, Yan-Fang Tao, Zhuan Zhou, Bang-rong Cao, Shui-Yan Wu, Yan-Lan Zhang, Shao-Yan Hu, Wen-Li Zhao, Jian Wang, Guo-Liang Lou, Zhen Li, Xing Feng and Jian Ni
    Citation: Journal of Translational Medicine 2011 9:157
  32. Downregulation of the putative tumor suppressor gene SLC22A18 has been reported in a number of human cancers. The aim of this study was to investigate the relationship between SLC22A18 downregulation, promoter me...

    Authors: Sheng-Hua Chu, Dong-Fu Feng, Yan-Bin Ma, Hong Zhang, Zhi-An Zhu, Zhi-Qiang Li and Pu-Cha Jiang
    Citation: Journal of Translational Medicine 2011 9:156
  33. Recent positive clinical results in cancer immunotherapy point to the potential of immune-based strategies to provide effective treatment of a variety of cancers. In some patients, the responses to cancer immu...

    Authors: Davide Bedognetti, James M Balwit, Ena Wang, Mary L Disis, Cedrik M Britten, Lucia G Delogu, Sara Tomei, Bernard A Fox, Thomas F Gajewski, Francesco M Marincola and Lisa H Butterfield
    Citation: Journal of Translational Medicine 2011 9:155
  34. The deafness-associated gene mutation profile varies greatly among regions and races. Due to the multi-ethnic coalition of over one thousand years, non-syndromic deafness (NSD) patients of Uyghur ethnicity may...

    Authors: Yu Chen, Mayila Tudi, Jie Sun, Chao He, Hong-li Lu, Qing Shang, Di Jiang, Pilidong Kuyaxi, Bin Hu and Hua Zhang
    Citation: Journal of Translational Medicine 2011 9:154
  35. The Cancer/Testis Antigens (CTAs) are an important group of proteins that are typically restricted to the testis in the normal adult but are aberrantly expressed in several types of cancers. As a result of the...

    Authors: Takumi Shiraishi, Naoki Terada, Yu Zeng, Takahito Suyama, Jun Luo, Bruce Trock, Prakash Kulkarni and Robert H Getzenberg
    Citation: Journal of Translational Medicine 2011 9:153
  36. Cancer is one of the most difficult current health challenges, being responsible for millions of deaths yearly. Systemic chemotherapy is the most common therapeutic approach, and the prevailing orientation cal...

    Authors: Enrico P Spugnini, Sylvie M Renaud, Sabrina Buglioni, Francesca Carocci, Emanuele Dragonetti, Raffaele Murace, Pierluigi Cardelli, Bruno Vincenzi, Alfonso Baldi and Gennaro Citro
    Citation: Journal of Translational Medicine 2011 9:152
  37. Active dendritic cell (DC) immunization protocols are rapidly gaining interest as therapeutic options in patients with acute myeloid leukemia (AML). Here we present for the first time a GMP-compliant 3-day pro...

    Authors: Barbara Beck, Daniela Dörfel, Felix S Lichtenegger, Christiane Geiger, Lysann Lindner, Martina Merk, Dolores J Schendel and Marion Subklewe
    Citation: Journal of Translational Medicine 2011 9:151
  38. Stem cell homing to the heart is mediated by the release of chemo-attractant cytokines. Stromal derived factor -1 alpha (SDF-1a) and monocyte chemotactic factor 1(MCP-1) are detectable in peripheral blood afte...

    Authors: Andrew J Boyle, Yerem Yeghiazarians, Henry Shih, Joy Hwang, Jianqin Ye, Rich Sievers, Daiwei Zheng, Jath Palasubramaniam, Dharshan Palasubramaniam, Connie Karschimkus, Robert Whitbourn, Alicia Jenkins and Andrew M Wilson
    Citation: Journal of Translational Medicine 2011 9:150
  39. With the approval of the first therapeutic cancer vaccines for veterinarian and human use, the field reached a significant milestone after a considerable interval of tumultuous research and development marked ...

    Authors: Adrian Bot, Mihail Obrocea and Francesco M Marincola
    Citation: Journal of Translational Medicine 2011 9:148
  40. Infection with high risk Human Papilloma Virus (HPV) is associated with cancer of the cervix, vagina, penis, vulva, anus and some cases of head and neck carcinomas. The HPV derived oncoproteins E6 and E7 are c...

    Authors: Kirsten BJ Scholten, Annelies W Turksma, Janneke J Ruizendaal, Muriel van den Hende, Sjoerd H van der Burg, Mirjam HM Heemskerk, Chris JLM Meijer and Erik Hooijberg
    Citation: Journal of Translational Medicine 2011 9:147
  41. The advent of high-throughput technology challenges the traditional histopathological classification of cancer, and proposes new taxonomies derived from global transcriptional patterns. Although most of these ...

    Authors: Maria Libera Ascierto, Valeria De Giorgi, Qiuzhen Liu, Davide Bedognetti, Tara L Spivey, Daniela Murtas, Lorenzo Uccellini, Ben D Ayotte, David F Stroncek, Lotfi Chouchane, Masoud H Manjili, Ena Wang and Francesco M Marincola
    Citation: Journal of Translational Medicine 2011 9:146
  42. Both endothelial progenitor cells (EPC) and markers of neuroinflammation are candidate biomarkers for stroke severity and outcome prediction. A relationship between EPC and neuroinflammatory markers in early s...

    Authors: Tanya Bogoslovsky, Maria Spatz, Aneeka Chaudhry, Dragan Maric, Marie Luby, Joseph Frank and Steven Warach
    Citation: Journal of Translational Medicine 2011 9:145
  43. The syndrome of resistance to thyroid hormone (RTH) is caused by mutations in the thyroid hormone receptor β gene (THRB). The syndrome varies from asymptomatic to diffuse hypothyroidism, to pituitary-selective re...

    Authors: Anna Teresa Alberobello, Valentina Congedo, Hong Liu, Craig Cochran, Monica C Skarulis, Douglas Forrest and Francesco S Celi
    Citation: Journal of Translational Medicine 2011 9:144
  44. The ability to measure T-cell responses to antigens is proving critical in the field of vaccine development and for understanding immunity to pathogens, allergens and self-antigens. Although a variety of techn...

    Authors: Aron Chakera, Sophia C Bennett and Richard J Cornall
    Citation: Journal of Translational Medicine 2011 9:143
  45. Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanism...

    Authors: María Valcárcel, Lorea Mendoza, José-Julio Hernández, Teresa Carrascal, Clarisa Salado, Olatz Crende and Fernando Vidal-Vanaclocha
    Citation: Journal of Translational Medicine 2011 9:142
  46. This study tested the superiority of combined cyclosporine A (CsA)-erythropoietin (EPO) therapy compared with either one in limiting brain infarction area (BIA) and preserving neurological function in rat afte...

    Authors: Chun-Man Yuen, Cheuk-Kwan Sun, Yu-Chun Lin, Li-Teh Chang, Ying-Hsien Kao, Chia-Hung Yen, Yung-Lung Chen, Tzu-Hsien Tsai, Sarah Chua, Pei-Lin Shao, Steve Leu and Hon-Kan Yip
    Citation: Journal of Translational Medicine 2011 9:141
  47. Active-specific immunotherapy used as an adjuvant therapeutic strategy is rather unexplored for cancers with poorly characterized tumor antigens like gastric cancer. The aim of this study was to augment a ther...

    Authors: Natasja K van den Engel, Dominik Rüttinger, Margareta Rusan, Robert Kammerer, Wolfgang Zimmermann, Rudolf A Hatz and Hauke Winter
    Citation: Journal of Translational Medicine 2011 9:140

Annual Journal Metrics

  • 2022 Citation Impact
    7.4 - 2-year Impact Factor
    6.9 - 5-year Impact Factor
    1.458 - SNIP (Source Normalized Impact per Paper)
    1.544 - SJR (SCImago Journal Rank)

    2022 Speed
    5 days submission to first editorial decision for all manuscripts (Median)
    84 days submission to accept (Median)

    2022 Usage 
    32,614 Altmetric mentions