Dolecek TA, Propp JM, Stroup NE, Kruchko C (2012) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005–2009. Neuro Oncol 14(Suppl 5):v1–v49. doi:10.1093/neuonc/nos218
Article
PubMed Central
PubMed
Google Scholar
Mawrin C, Perry A (2010) Pathological classification and molecular genetics of meningiomas. J Neurooncol 99(3):379–391. doi:10.1007/s11060-010-0342-2
Article
CAS
PubMed
Google Scholar
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) (2007) WHO classification of tumours of the central nervous system, 2007th edn. IARC, Lyon
Google Scholar
Alexiou GA, Gogou P, Markoula S, Kyritsis AP (2010) Management of meningiomas. Clin Neurol Neurosurg 112(3):177–182. doi:10.1016/j.clineuro.2009.12.011
Article
PubMed
Google Scholar
Moazzam AA, Wagle N, Zada G (2013) Recent developments in chemotherapy for meningiomas: a review. Neurosurg Focus 35(6):E18. doi:10.3171/2013.10.FOCUS13341
Article
PubMed
Google Scholar
Lee WH (1990) Characterization of a newly established malignant meningioma cell line of the human brain: IOMM-Lee. Neurosurgery 27(3):389–395 (discussion 96)
Article
CAS
PubMed
Google Scholar
Yazaki T, Takamiya Y, Costello PC, Mineta T, Menon AG, Rabkin SD et al (1995) Inhibition of angiogenesis and growth of human non-malignant and malignant meningiomas by TNP-470. J Neurooncol 23(1):23–29
Article
CAS
PubMed
Google Scholar
Tanaka K, Sato C, Maeda Y, Koike M, Matsutani M, Yamada K et al (1989) Establishment of a human malignant meningioma cell line with amplified c-myc oncogene. Cancer 64(11):2243–2249
Article
CAS
PubMed
Google Scholar
Ishiwata I, Ishiwata C, Ishiwata E, Sato Y, Kiguchi K, Tachibana T et al (2004) In vitro culture of various typed meningiomas and characterization of a human malignant meningioma cell line (HKBMM). Hum Cell 17(4):211–217
Article
PubMed
Google Scholar
Cargioli TG, Ugur HC, Ramakrishna N, Chan J, Black PM, Carroll RS (2007) Establishment of an in vivo meningioma model with human telomerase reverse transcriptase. Neurosurgery 60(4):750–759 (discussion 9–60)
Article
PubMed
Google Scholar
Puttmann S, Senner V, Braune S, Hillmann B, Exeler R, Rickert CH et al (2005) Establishment of a benign meningioma cell line by hTERT-mediated immortalization. Lab Invest 85(9):1163–1171. doi:10.1038/labinvest.3700307
Article
PubMed
Google Scholar
Baia GS, Slocum AL, Hyer JD, Misra A, Sehati N, VandenBerg SR et al (2006) A genetic strategy to overcome the senescence of primary meningioma cell cultures. J Neurooncol 78(2):113–121. doi:10.1007/s11060-005-9076-y
Article
CAS
PubMed
Google Scholar
Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A (2008) The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP. Neoplasia 10(11):1204–1212
Article
CAS
PubMed Central
PubMed
Google Scholar
Simon M, Park TW, Leuenroth S, Hans VH, Loning T, Schramm J (2000) Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progression. J Neurosurg 92(5):832–840
Article
CAS
PubMed
Google Scholar
Maes L, Van Neste L, Van Damme K, Kalala JP, De Ridder L, Bekaert S et al (2007) Relation between telomerase activity, hTERT and telomere length for intracranial tumours. Oncol Rep 18(6):1571–1576
CAS
PubMed
Google Scholar
Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M et al (2008) Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathol 18(1):62–70. doi:10.1111/j.1750-3639.2007.00105.x
Article
PubMed Central
PubMed
Google Scholar
Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C et al (2013) Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation. Oncogene 32(36):4264–4272. doi:10.1038/onc.2012.436
Article
CAS
PubMed
Google Scholar
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T et al (2014) A comparative encyclopedia of DNA elements in the mouse genome. Nature 515(7527):355–364. doi:10.1038/nature13992
Article
CAS
PubMed Central
PubMed
Google Scholar
Siolas D, Hannon GJ (2013) Patient-derived tumor xenografts: transforming clinical samples into mouse models. Cancer Res 73(17):5315–5319. doi:10.1158/0008-5472.CAN-13-1069
Article
CAS
PubMed Central
PubMed
Google Scholar
Lamszus K (2004) Meningioma pathology, genetics, and biology. J Neuropathol Exp Neurol 63(4):275–286
PubMed
Google Scholar
Perry A, Gutmann DH, Reifenberger G (2004) Molecular pathogenesis of meningiomas. J Neurooncol 70(2):183–202
Article
PubMed
Google Scholar
Zang KD (2001) Meningioma: a cytogenetic model of a complex benign human tumor, including data on 394 karyotyped cases. Cytogenet Cell Genet 93(3–4):207–220
Article
CAS
PubMed
Google Scholar
Mark J, Levan G, Mitelman F (1972) Identification by fluorescence of the G chromosome lost in human meningomas. Hereditas 71(1):163–168
Article
CAS
PubMed
Google Scholar
Zankl H, Zang KD (1972) Cytological and cytogenetical studies on brain tumors. 4. Identification of the missing G chromosome in human meningiomas as no. 22 by fluorescence technique. Humangenetik 14(2):167–169
Article
CAS
PubMed
Google Scholar
Choy W, Kim W, Nagasawa D, Stramotas S, Yew A, Gopen Q et al (2011) The molecular genetics and tumor pathogenesis of meningiomas and the future directions of meningioma treatments. Neurosurg Focus 30(5):E6. doi:10.3171/2011.2.FOCUS1116
PubMed
Google Scholar
Al-Mefty O, Kadri PA, Pravdenkova S, Sawyer JR, Stangeby C, Husain M (2004) Malignant progression in meningioma: documentation of a series and analysis of cytogenetic findings. J Neurosurg 101(2):210–218
Article
PubMed
Google Scholar
Jansen M, Mohapatra G, Betensky RA, Keohane C, Louis DN (2012) Gain of chromosome arm 1q in atypical meningioma correlates with shorter progression-free survival. Neuropathol Appl Neurobiol 38(2):213–219. doi:10.1111/j.365-2990.011.01222.x
Article
CAS
PubMed Central
PubMed
Google Scholar
Christodoulidou A, Raftopoulou C, Chiourea M, Papaioannou GK, Hoshiyama H, Wright WE et al (2013) The roles of telomerase in the generation of polyploidy during neoplastic cell growth. Neoplasia 15(2):156–168
Article
CAS
PubMed Central
PubMed
Google Scholar
Zitron IM, Kamson DO, Kiousis S, Juhasz C, Mittal S (2013) In vivo metabolism of tryptophan in meningiomas is mediated by indoleamine 2,3-dioxygenase 1. Cancer Biol Ther 14(4):333–339
Article
CAS
PubMed Central
PubMed
Google Scholar
Bosnyák E, Kamson DO, Guastella AR, Varadarajan K, Robinette NL, Kupsky WJ et al (2015) Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas. Neuro Oncol. doi:10.1093/neuonc/nov098
PubMed
Google Scholar
Barch M (1991) ACT cytogenetics laboratory manual, 2nd edn. Raven Press NYC, New York
Google Scholar
Shaffer LG, McGowan-Jordan J, Schmid M (eds) (2013) ISCN 2013: an international system for human cytogenetic nomenclature, 1st edn. S. Karger AG, Basel
Futreal PA, Coin L, Marshall M, Down T, Hubbard T, Wooster R et al (2004) A census of human cancer genes. Nat Rev Cancer 4(3):177–183. doi:10.1038/nrc1299
Article
CAS
PubMed Central
PubMed
Google Scholar
Tsai JC, Goldman CK, Gillespie GY (1995) Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF. J Neurosurg 82(5):864–873
Article
CAS
PubMed
Google Scholar
Speicher MR, Carter NP (2005) The new cytogenetics: blurring the boundaries with molecular biology. Nat Rev Genet 6(10):782–792. doi:10.1038/nrg1692
Article
CAS
PubMed
Google Scholar
Kallio M, Sankila R, Hakulinen T, Jaaskelainen J (1992) Factors affecting operative and excess long-term mortality in 935 patients with intracranial meningioma. Neurosurgery 31(1):2–12
Article
CAS
PubMed
Google Scholar
Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL (1985) Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 62(1):18–24
Article
CAS
PubMed
Google Scholar
Perry A, Scheithauer BW, Stafford SL, Lohse CM, Wollan PC (1999) “Malignancy” in meningiomas: a clinicopathologic study of 116 patients, with grading implications. Cancer 85(9):2046–2056
CAS
PubMed
Google Scholar
Dziuk TW, Woo S, Butler EB, Thornby J, Grossman R, Dennis WS et al (1998) Malignant meningioma: an indication for initial aggressive surgery and adjuvant radiotherapy. J Neurooncol 37(2):177–188
Article
CAS
PubMed
Google Scholar
Jaaskelainen J, Haltia M, Servo A (1986) Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy, and outcome. Surg Neurol 25(3):233–242
Article
CAS
PubMed
Google Scholar
Goldsmith BJ, Wara WM, Wilson CB, Larson DA (1994) Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg 80(2):195–201
Article
CAS
PubMed
Google Scholar
Adeberg S, Hartmann C, Welzel T, Rieken S, Habermehl D, von Deimling A et al (2012) Long-term outcome after radiotherapy in patients with atypical and malignant meningiomas—clinical results in 85 patients treated in a single institution leading to optimized guidelines for early radiation therapy. Int J Radiat Oncol Biol Phys 83(3):859–864. doi:10.1016/j.ijrobp.2011.08.010
Article
PubMed
Google Scholar
Kaur G, Sayegh ET, Larson A, Bloch O, Madden M, Sun MZ et al (2014) Adjuvant radiotherapy for atypical and malignant meningiomas: a systematic review. Neuro Oncol 16(5):628–636. doi:10.1093/neuonc/nou025
Article
PubMed Central
PubMed
Google Scholar
Ragel BT, Couldwell WT, Gillespie DL, Wendland MM, Whang K, Jensen RL (2008) A comparison of the cell lines used in meningioma research. Surg Neurol 70(3):295–307. doi:10.1016/j.surneu.2007.06.031
Article
PubMed
Google Scholar
Pravdenkova S, Al-Mefty O, Sawyer J, Husain M (2006) Progesterone and estrogen receptors: opposing prognostic indicators in meningiomas. J Neurosurg 105(2):163–173. doi:10.3171/jns.2006.105.2.163
Article
CAS
PubMed
Google Scholar
Van Marck VL, Bracke ME (2000) Epithelial–mesenchymal transitions in human cancer. Madame Curie Bioscience Database [Internet]. Landes Bioscience, Austin
Nagaishi M, Nobusawa S, Tanaka Y, Ikota H, Yokoo H, Nakazato Y (2012) Slug, twist, and E-cadherin as immunohistochemical biomarkers in meningeal tumors. PLoS One 7(9):e46053. doi:10.1371/journal.pone.0046053
Article
CAS
PubMed Central
PubMed
Google Scholar
Zhang X, Liu G, Kang Y, Dong Z, Qian Q, Ma X (2013) N-cadherin expression is associated with acquisition of EMT phenotype and with enhanced invasion in erlotinib-resistant lung cancer cell lines. PLoS One 8(3):e57692. doi:10.1371/journal.pone.0057692
Article
CAS
PubMed Central
PubMed
Google Scholar
Nakajima S, Doi R, Toyoda E, Tsuji S, Wada M, Koizumi M et al (2004) N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma. Clin Cancer Res 10(12 Pt 1):4125–4133. doi:10.1158/1078-0432.CCR-0578-03
Article
CAS
PubMed
Google Scholar
Pecina-Slaus N, Cicvara-Pecina T, Kafka A (2012) Epithelial-to-mesenchymal transition: possible role in meningiomas. Front Biosci (Elite Ed) 4:889–896
Article
Google Scholar
Mocellin S, Pooley KA, Nitti D (2013) Telomerase and the search for the end of cancer. Trends Mol Med 19(2):125–133. doi:10.1016/j.molmed.2012.11.006
Article
CAS
PubMed
Google Scholar
De Lange T (2005) Telomere-related genome instability in cancer. Cold Spring Harb Symp Quant Biol 70:197–204. doi:10.1101/sqb.2005.70.032
Article
PubMed
Google Scholar
Chen HJ, Liang CL, Lu K, Lin JW, Cho CL (2000) Implication of telomerase activity and alternations of telomere length in the histologic characteristics of intracranial meningiomas. Cancer 89(10):2092–2098
Article
CAS
PubMed
Google Scholar
Langford LA, Piatyszek MA, Xu R, Schold SC Jr, Wright WE, Shay JW (1997) Telomerase activity in ordinary meningiomas predicts poor outcome. Hum Pathol 28(4):416–420
Article
CAS
PubMed
Google Scholar
Leuraud P, Dezamis E, Aguirre-Cruz L, Taillibert S, Lejeune J, Robin E et al (2004) Prognostic value of allelic losses and telomerase activity in meningiomas. J Neurosurg 100(2):303–309
Article
CAS
PubMed
Google Scholar
Urbschat S, Rahnenfuhrer J, Henn W, Feiden W, Wemmert S, Linsler S et al (2011) Clonal cytogenetic progression within intratumorally heterogeneous meningiomas predicts tumor recurrence. Int J Oncol 39(6):1601–1608. doi:10.3892/ijo.2011.1199
PubMed
Google Scholar
Goutagny S, Nault JC, Mallet M, Henin D, Rossi JZ, Kalamarides M (2014) High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression. Brain Pathol 24(2):184–189. doi:10.1111/bpa.12110
Article
CAS
PubMed
Google Scholar