Volume 8 Supplement 1

5th European Workshop on Immune-Mediated Inflammatory Diseases

Meeting abstracts

Edited by Ricardo Pujol-Borrell and Dominique L Baeten

5th European Workshop on Immune-Mediated Inflammatory Diseases. Go to conference site.

Sitges-Barcelona, Spain1-3 December 2010

Concatenated PDF 8S1

Page 1 of 2

Immunosurveillance by gamma delta T cells - lessons from the cancer field

Authors: A C Hayday, E Binda, A Robert, M Serrano and F Dieli

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I1

Content type: Invited lecture presentation

Published on: 25 November 2010
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A genomic approach to biomarker discovery in human autoimmune diseases

Authors: V Pascual

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I2

Content type: Invited lecture presentation

Published on: 25 November 2010
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Skin-derived tumor specific T cells predict clinical outcome in dendritic cell vaccination studies in both stage III and IV melanoma patients

Authors: EHJG Aarntzen, W J Lesterhuis, M Van Rossum, G J Adema, C F Figdor, CJA Punt and IJM De Vries

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I3

Content type: Invited lecture presentation

Published on: 25 November 2010
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HLA guided epitope discovery in Type 1 diabetes to generate novel therapeutics

Authors: M Peakman

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I4

Content type: Invited lecture presentation

Published on: 25 November 2010
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GWAS in IMIDs

Authors: R M Plenge

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I5

Content type: Invited lecture presentation

Published on: 25 November 2010
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Crohn’s disease is caused by a failure of the innate immune response with major abnormalities in macrophage biology

Authors: A W Segal

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I6

Content type: Invited lecture presentation

Published on: 25 November 2010
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RNA interference and viruses in mammalian cells

Authors: B Monsef

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I7

Content type: Invited lecture presentation

Published on: 25 November 2010
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MicroRNAs in the context of human diseases

Authors: E Sonkoly

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I8

Content type: Invited lecture presentation

Published on: 25 November 2010
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Human T helper cells in immunity and autoimmunity: Th17 and beyond

Authors: F Sallusto

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I9

Content type: Invited lecture presentation

Published on: 25 November 2010
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Exploring new inflammatory pathways in the synovium

Authors: I B McInnes

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I10

Content type: Invited lecture presentation

Published on: 25 November 2010
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Primary antibody deficiencies in the context of normal B-cell differentiation

Authors: M van der Burg

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I11

Content type: Invited lecture presentation

Published on: 25 November 2010
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Early-onset inflammatory bowel disease caused by mutant IL10 receptor

Authors: E O Glocker, D Kotlarz, K Boztug, E M Gertz, A A Schäffer, F Noyan, M Perro, J Diestelhorst, A Allroth, D Murugan, N Hätscher, D Pfeifer, K W Sykora, M Sauer, H Kreipe, M Lacher…

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I12

Content type: Invited lecture presentation

Published on: 25 November 2010
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Chemokines as inflammatory mediators of fibrosis in liver fibrosis

Authors: H E Wasmuth

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I13

Content type: Invited lecture presentation

Published on: 25 November 2010
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Biomarkers inform clinical trials and pathogenesis in systemic sclerosis

Authors: R Lafyatis

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I14

Content type: Invited lecture presentation

Published on: 25 November 2010
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Mechanisms of accelerated atherosclerosis associated with IMIDs

Authors: Z Mallat

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I15

Content type: Invited lecture presentation

Published on: 25 November 2010
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Understanding the molecular bases of tissue inflammation

Authors: R A Flavell

Citation: Journal of Translational Medicine 2010 8(Suppl 1):I16

Content type: Invited lecture presentation

Published on: 25 November 2010
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Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy

Authors: O Gorlova, J M Martin, B Rueda, BPC Koeleman, J Ying, M Teruel, L M Diaz-Gallo, J C Broen, M C Vonk, C P Simeon, B Z Alizadeh, MJH Coenen, A E Voskuyl, A J Schuerwegh, PLCM van Riel, M Vanthuyne…

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O1

Content type: Oral presentation

Published on: 25 November 2010
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Linking genotype to cell function in chronic inflammation: analysis of the IL-23/Th17 axis in spondylarthropathy

Authors: M Roumier, M Coffre, H Law, C Salliot, M Dougados, E Bianchi and L Rogge

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O2

Content type: Oral presentation

Published on: 25 November 2010
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Cytosolic phospholipase A2α gene silencing in monocytes alters development of Th1 responses and reduces autoimmune arthritis

Authors: G Courties, J Presumey, M Baron, V Escriou, P Van Lent, D Scherman, A Cantagrel, W Van den Berg, C Jorgensen, J-L Davignon and F Apparailly

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O3

Content type: Oral presentation

Published on: 25 November 2010
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RANKL expression in human T-lymphocytes requires cooperative signaling through the T-cell receptor and adhesion molecule CD2

Authors: B P Harvey and Z Kaymakcalan

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O4

Content type: Oral presentation

Published on: 25 November 2010
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Single-cell analysis techniques reveal a striking heterogeneity of human CD4⁺ T cell subsets

Authors: M Coffre, K Placek, S Maiella, E Bianchi and L Rogge

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O5

Content type: Oral presentation

Published on: 25 November 2010
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Sustained T cell Rap1 activation protects against Experimental Autoimmune Encephalomyelitis (EAE) via modulation of T cell responses

Authors: G Franco Salinas, S Krausz, W Dontje, P P Tak, D Baeten and K Reedquist

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O6

Content type: Oral presentation

Published on: 25 November 2010
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Skewed X-chromosomal inactivation impacts T regulatory cell function in systemic sclerosis

Authors: JCA Broen, ILM Wolvers-Tettero, L Geurts-van Bon, M C Vonk, MJH Coenen, R Lafyatis, TRDJ Radstake and A W Langerak

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O7

Content type: Oral presentation

Published on: 25 November 2010
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Fra-1 regulates inflammatory and degenerative arthritis

Authors: T Kireva, K Zwerina, W Baum, S Hayer, G Schett and J Zwerina

Citation: Journal of Translational Medicine 2010 8(Suppl 1):O8

Content type: Oral presentation

Published on: 25 November 2010
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The neonatal Fc receptor is expressed by human lymphocytes

Authors: K van Bilsen, J Bastiaans, W A Dik, E F De Haas, S G Baarsma, R W Kuipers and P M van Hagen

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P1

Content type: Poster presentation

Published on: 25 November 2010
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Differential association of two PTPN22 coding variants with Crohn’s disease and ulcerative colitis

Authors: L M Diaz-Gallo, L Espino-Paisán, K Fransen, M Gómez-García, S van Sommeren, C Cardeña, L Rodrigo, J L Mendoza, C Taxonera, A Nieto, G Alcain, I Cueto, M A López-Nevot, N Bottini, M L Barclay, J B Crusius…

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P2

Content type: Poster presentation

Published on: 25 November 2010
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Single-cell gene profiling analysis of human regulatory T cell subsets

Authors: S Maiella, S Dong, C Becavin, M Coffre, K Placek, E Bianchi, A Benecke and L Rogge

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P3

Content type: Poster presentation

Published on: 25 November 2010
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TLR signals modify the expression of scavenger receptors

Authors: C Zamora, E Cantó, J C Nieto, C Juarez and S Vidal

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P4

Content type: Poster presentation

Published on: 25 November 2010
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A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort

Authors: L Bossini-Castillo, JCA Broen, C P Simeon, L Beretta, M C Vonk, N Ortego-Centeno, G Espinosa, P Carreira, M T Camps, N Navarrete, M F González-Escribano, E Vicente-Rabaneda, L Rodríguez, C Tolosa, J A Román-Ivorra, I Gómez-Gracia…

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P5

Content type: Poster presentation

Published on: 25 November 2010
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IMID-Biobank: Biobank of immune-mediated inflammatory diseases (IMIDs)

Authors: S Marsal, J Cañete, J Tornero, A Fernandez-Nebro, J M Hernanz, J Panes, A Julià and R Tortosa

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P6

Content type: Poster presentation

Published on: 25 November 2010
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Genetic polymorphisms of inflammatory molecules in Tunisian inflammatory bowel diseases

Authors: Y Gorgi, W Ben Aleya, D Khazen, I Sfar, H Aounallah-Skhiri, L Mouelhi, S Jendoubi-Ayed, M Makhlouf, T Ben Rhomdhane, S Matri, A Filali, H Aouadi, T Najjar, K Ayed and T Ben Abdallah

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P7

Content type: Poster presentation

Published on: 25 November 2010
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Cytokines and apoptosis genes polymorphisms influence the outcome of hepatitis C virus infection

Authors: L Ksiaa-Cheikh Rouhou, I Sfar, H Aounallah-Skhiri, H Aouadi, S Jendoubi-Ayed, T Ben Abdallah, K Ayed and Y Lakhoua-Gorgi

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P8

Content type: Poster presentation

Published on: 25 November 2010
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Lack of adalimumab's complement dependent cytotoxicity on human cells expressing complement regulatory proteins

Authors: K M Grebe, J Salfeld and Z Kaymakcalan

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P9

Content type: Poster presentation

Published on: 25 November 2010
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Efficacy of adalimumab in sarcoidosis

Authors: LSJ Kamphuis, W K Lam-Tse, W A Dik, J Bastiaans, P van Biezen, PLA van Daele, D J Kwekkeboom, RWAM Kuijpers, G S Baarsma, P M van Hagen, H Hooijkaas and JAM van Laar

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P10

Content type: Poster presentation

Published on: 25 November 2010
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Differences in virus prevalence and load in the hearts of patients with chronic dilated cardiomyopathy with and without immune-mediated inflammatory disease

Authors: R Dennert, P van Paassen, C Bruggeman, P Wolffs, J W Cohen Tervaert and S Heymans

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P11

Content type: Poster presentation

Published on: 25 November 2010
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Inflammatory T-lymphocyte proliferation in morbid obesity

Authors: K Van der Weerd, P M van Hagen, W A Dik, B S Schrijver, D H Schweitzer, A W Langerak, R M Kiewiet, M O Van Aken, JJM Van Dongen, A J Van der Lelij and FJT Staal

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P12

Content type: Poster presentation

Published on: 25 November 2010
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Elevated soluble Flt1 mediates an anti-angiogenic state in patients with ANCA-associated vasculitis

Authors: S Le Roux, R Pepper, A Dufay, M Néel, N Lamandé, M Rimbert, R Josien, M Hamidou, M Hourmant, H T Cook, B Charreau, E Larger, A Salama and F Fakhouri

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P13

Content type: Poster presentation

Published on: 25 November 2010
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Functional relevance of a non-synonymous substitution in the CD5 gene (V471A) targeted for positive selection in East Asian populations

Authors: T Bielig, E Carnero-Montoro, L Bonet, J Engelken, M Arias, E Bosch and F Lozano

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P14

Content type: Poster presentation

Published on: 25 November 2010
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Atopy in cutaneous and arthropatic psoriasis

Authors: E Hajdarbegovic, AAA Westgeest and H B Thio

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P15

Content type: Poster presentation

Published on: 25 November 2010
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Safety of treatment with biologics for psoriasis in daily practice: 5-year data

Authors: PPM Van Lümig, RJB Driessen, MAM Berends, J B Boezeman, PCM van de Kerkhof and EMGJ de Jong

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P16

Content type: Poster presentation

Published on: 25 November 2010
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CCL4L polymorphisms and serum levels are associated with psoriasis severity

Authors: E Pedrosa, L Carretero-Iglesia, A Boada, R Colobran, I Pujol-Autonell, R Pujol-Borrell, C Ferrándiz, M Juan and J M Carrascosa

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P17

Content type: Poster presentation

Published on: 25 November 2010
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Demonstration of novel innate immune cells in psoriasis

Authors: R Mak, C Hundhausen, E Botti, U Laggner, K Grys, I Tosi and F O Nestle

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P18

Content type: Poster presentation

Published on: 25 November 2010
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Expression of IL-1 family members upon stimulation with IL-17 differs in keratinocytes derived from psoriasis patients and healthy donors

Authors: P Muhr, J Zeitvogel, T Werfel and M Wittmann

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P19

Content type: Poster presentation

Published on: 25 November 2010
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Mutations in the Fas gene found in Spanish ALPS (autoimmune lymphoproliferative syndrome) patients

Authors: L Martínez-Martínez, C González-Santesteban, M V Rubiales, M Orta, I Badell and O de la Calle-Martin

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P20

Content type: Poster presentation

Published on: 25 November 2010
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Discovery and validation of immunological biomarkers using an advanced flow cytometry platform

Authors: F Villanova, P Di Meglio, M Inokuma, V C Maino and F O Nestle

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P21

Content type: Poster presentation

Published on: 25 November 2010
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Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

Authors: L Van Steensel, D Paridaens, P M van Hagen, RWAM Kuijpers, W A Van den Bosch, H A Drexhage, H Hooijkaas and W A Dik

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P22

Content type: Poster presentation

Published on: 25 November 2010
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Perivascular adipocytes and signaling through toll-like receptors: role in the pathophysiology of atherosclerosis

Authors: C Benaiges, X Garcia-Moll, E Mateus, C Muñoz, E Cantó, E Pérez, R Leta, E Moga, S Vidal and C Juarez

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P23

Content type: Poster presentation

Published on: 25 November 2010
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Modulation of oxidative stress and TNFα secretion by peritoneal macrophages of arthritic rats fed with a flavonoid-enriched diet

Authors: S Ramos-Romero, F J Pérez-Cano, C Ramírez-Santana, C Castellote, A Franch and M Castell

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P24

Content type: Poster presentation

Published on: 25 November 2010
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Cocoa diet diminishes the anti-collagen humoral response in collagen-induced arthritis in rats

Authors: S Ramos-Romero, T Pérez-Berezo, F J Pérez-Cano, C Castellote, M Castell and A Franch

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P25

Content type: Poster presentation

Published on: 25 November 2010
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Toll-like receptor ligands regulate the migratory pattern of leukocytes

Authors: J C Nieto, E Cantó, M A Ortiz, C Juarez and S Vidal

Citation: Journal of Translational Medicine 2010 8(Suppl 1):P26

Content type: Poster presentation

Published on: 25 November 2010
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