Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30.
Article
Google Scholar
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
Article
Google Scholar
Cortez AJ, Tudrej P, Kujawa KA, Lisowska KM. Advances in ovarian cancer therapy. Cancer Chemother Pharmacol. 2018;81(1):17–38.
Article
CAS
Google Scholar
Webb PM, Jordan SJ. Epidemiology of epithelial ovarian cancer. Best Pract Res Clin Obstet Gynaecol. 2017;41:3–14.
Article
Google Scholar
Schmit K, Michiels C. TMEM proteins in cancer: a review. Front Pharmacol. 2018;9:1345.
Article
CAS
Google Scholar
Sebastien M, Thomas D, Chen JW, Marina B, Johan W, Carine M, Benjamin L. Transmembrane (TMEM) protein family members: Poorly characterized even if essential for the metastatic process. Semin Cancer Biol. 2020;60:96–106.
Article
Google Scholar
Hrasovec S, Hauptman N, Glavac D, Jelenc F, Ravnik-Glavac M. TMEM25 is a candidate biomarker methylated and down-regulated in colorectal cancer. Dis Markers. 2013;34(2):93–104.
Article
CAS
Google Scholar
Cheng ZP, Guo J, Chen L, Luo N, Yang WH, Qu XY. Overexpression of TMEM158 contributes to ovarian carcinogenesis. J Exp Clin Canc Res. 2015. https://doi.org/10.1186/s13046-015-0193-y.
Article
Google Scholar
Guo J, Chen L, Luo N, Yang WH, Qu XY, Cheng ZP. Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells. Oncol Rep. 2015;33(6):3124–30.
Article
CAS
Google Scholar
Zheng LL, Chen LL, Zhang X, Zhan JF, Chen J. TMEM49-related apoptosis and metastasis in ovarian cancer and regulated cell death. Mol Cell Biochem. 2016;416(1–2):1–9.
Article
CAS
Google Scholar
de Leon M, Cardenas H, Vieth E, Emerson R, Segar M, Liu YL, Nephew K, Matei D. Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer. Gynecol Oncol. 2016;142(3):539–47.
Article
Google Scholar
Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H, Furukawa T. Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation. Bmc Dev Biol. 2009;9:70.
Article
Google Scholar
Zheng PF, Wang WF, Ji MX, Zhu Q, Feng YL, Zhou F, He QN. TMEM119 silencing inhibits cell viability and causes the apoptosis of gastric cancer SGC-7901 cells. Oncol Lett. 2018;15(6):8281–6.
PubMed
PubMed Central
Google Scholar
Jiang ZH, Peng J, Yang HL, Fu XL, Wang JZ, Liu L, Jiang JN, Tan YF, Ge ZJ. Upregulation and biological function of transmembrane protein 119 in osteosarcoma. Exp Mol Med. 2017;49:e329.
Article
CAS
Google Scholar
Tandefelt DG, Boormans JL, van der Korput HA, Jenster GW, Trapman J. A 36-gene signature predicts clinical progression in a subgroup of ERG-positive prostate cancers. Eur Urol. 2013;64(6):941–50.
Article
Google Scholar
Tang ZF, Li CW, Kang BX, Gao G, Li C, Zhang ZM. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res. 2017;45(W1):W98–102.
Article
CAS
Google Scholar
Gyorffy B, Lanczky A, Szallasi Z. Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients. Endocr-Relat Cancer. 2012;19(2):197–208.
Article
CAS
Google Scholar
KEGG PATHWAY: Focal adhesion—Homo sapiens (human). https://www.genome.jp/kegg/pathway/hsa/hsa04510.html. Accessed 18 May 2020.
Chang KK, Yoon C, Yi BC, Tap WD, Simon MC, Yoon SS. Platelet-derived growth factor receptor-alpha and -beta promote cancer stem cell phenotypes in sarcomas. Oncogenesis. 2018. https://doi.org/10.1038/s41389-018-0059-1.
Article
PubMed
PubMed Central
Google Scholar
Zhang Z, Ren XM, Lu XY, Wang DP, Hu XJ, Zheng Y, Song LY, Pang HW, Yu RM, Ding K. GZD856, a novel potent PDGFR alpha/beta inhibitor, suppresses the growth and migration of lung cancer cells in vitro and in vivo. Cancer Lett. 2016;375(1):172–8.
Article
CAS
Google Scholar
Ediriweera MK, Tennekoon KH, Samarakoon SR. Role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer: biological and therapeutic significance. Semin Cancer Biol. 2019;59:147–60.
Article
CAS
Google Scholar
Bai KH, He SY, Shu LL, Wang WD, Lin SY, Zhang QY, Li L, Cheng L, Dai YJ. Identification of cancer stem cell characteristics in liver hepatocellular carcinoma by WGCNA analysis of transcriptome stemness index. Cancer Med-Us. 2020;9(12):4290–8.
Article
CAS
Google Scholar
Zheng PF, Wang WF, Ji MX, Zhu Q, Feng YL, Zhou F, He QN. TMEM119 promotes gastric cancer cell migration and invasion through STAT3 signaling pathway. Oncotargets Ther. 2018;11:5835–44.
Article
CAS
Google Scholar
Gronwald RG, Grant FJ, Haldeman BA, Hart CE, O’Hara PJ, Hagen FS, Ross R, Bowen-Pope DF, Murray MJ. Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class. Proc Natl Acad Sci U S A. 1988;85(10):3435–9.
Article
CAS
Google Scholar
Kazlauskas A, Durden DL, Cooper JA. Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit. Cell Regul. 1991;2(6):413–25.
Article
CAS
Google Scholar
Kim HJ, Cha BY, Choi B, Lim JS, Woo JT, Kim JS. Glyceollins inhibit platelet-derived growth factor-mediated human arterial smooth muscle cell proliferation and migration. Brit J Nutr. 2012;107(1):24–35.
Article
CAS
Google Scholar
Wardega P, Heldin CH, Lennartsson J. Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration. Cell Signal. 2010;22(9):1363–8.
Article
CAS
Google Scholar
Forte L, Turdo F, Ghirelli C, Aiello P, Casalini P, Iorio MV, D’Ippolito E, Gasparini P, Agresti R, Belmonte B, et al. The PDGFR beta/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer. BMC Cancer. 2018. https://doi.org/10.1186/s12885-018-4500-9.
Article
PubMed
PubMed Central
Google Scholar
Matei D, Kelich S, Coa L, Menning N, Ernerson RE, Rao J, Jeng MH, Sledge GW. PDGF BB induces VEGF secretion in ovarian cancer. Cancer Biol Ther. 2007;6(12):1951–9.
Article
CAS
Google Scholar
Wilczynski SP, Chen YY, Chen W, Howell SB, Shively JE, Alberts DS. Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFR alpha, and PDGFR beta in ovarian cancers. Hum Pathol. 2005;36(3):242–9.
Article
CAS
Google Scholar
Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ. Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecol Oncol. 2004;93(1):78–86.
Article
CAS
Google Scholar
Marx S, Dal Maso T, Chen JW, Bury M, Wouters J, Michiels C, Le Calvé B. Transmembrane (TMEM) protein family members: poorly characterized even if essential for the metastatic process. Semin Cancer Biol. 2020;60:96–106.
Article
CAS
Google Scholar
Mizuhashi K, Chaya T, Kanamoto T, Omori Y, Furukawa T. Obif, a transmembrane protein, is required for bone mineralization and spermatogenesis in mice. PLoS ONE. 2015;10(7):e0133704.
Article
Google Scholar
Hisa I, Inoue Y, Hendy GN, Canaff L, Kitazawa R, Kitazawa S, Komori T, Sugimoto T, Seino S, Kaji H. Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway. J Biol Chem. 2011;286(11):9787–96.
Article
CAS
Google Scholar
Shukla PK, Meena AS, Rao R. Prevention and mitigation of alcohol-induced neuroinflammation by Lactobacillus plantarum by an EGF receptor-dependent mechanism. Nutr Neurosci. 2020. https://doi.org/10.1080/1028415X.2020.1819105.
Article
PubMed
Google Scholar
Huang XJ, Liu GH, Guo J, Su ZQ. The PI3K/AKT pathway in obesity and type 2 diabetes. Int J Biol Sci. 2018;14(11):1483–96.
Article
CAS
Google Scholar
Chen HX, Zhou L, Wu XR, Li RB, Wen JL, Sha JJ, Wen XF. The PI3K/AKT pathway in the pathogenesis of prostate cancer. Front Biosci-Landmrk. 2016;21:1084–91.
Article
CAS
Google Scholar
Ao R, Guan L, Wang Y, Wang JN. Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k-Akt signaling pathway. J Cell Biochem. 2018;119(6):4420–34.
Article
CAS
Google Scholar
Sarker D, Ang JE, Baird R, Kristeleit R, Shah K, Moreno V, Clarke PA, Raynaud FI, Levy G, Ware JA, et al. First-in-human phase i study of pictilisib (GDC-0941), a potent pan-class i phosphatidylinositol-3-kinase (PI3K) inhibitor, in patients with advanced solid tumors. Clin Cancer Res. 2015;21(1):77–86.
Article
CAS
Google Scholar
Matulonis UA, Wulf GM, Barry WT, Birrer M, Westin SN, Farooq S, Bell-McGuinn KM, Obermayer E, Whalen C, Spagnoletti T, et al. Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer. Ann Oncol. 2017;28(3):512–8.
Article
CAS
Google Scholar
Salha S, Gehmert S, Brebant V, Anker A, Loibl M, Prantl L, Gehmert S. PDGF regulated migration of mesenchymal stem cells towards malignancy acts via the PI3K signaling pathway. Clin Hemorheol Micro. 2018;70(4):543–51.
CAS
Google Scholar
Heldin CH, Lennartsson J, Westermark B. Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis. J Intern Med. 2018;283(1):16–44.
Article
CAS
Google Scholar