Guo W, Wu S, Liu J, Fang B: Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 2008, 68: 7403-7408. 10.1158/0008-5472.CAN-08-1449.
Wei X, Guo W, Wu S, Wang L, Lu Y, Xu B, Liu J, Fang B: Inhibiting JNK dephosphorylation and induction of apoptosis by a novel anticancer agent NSC-741909 in cancer cells. J Biol Chem. 2009, 284: 16948-16955. 10.1074/jbc.M109.010256.
Davis RJ: Signal transduction by the JNK group of MAP kinases. Cell. 2000, 103: 239-252. 10.1016/S0092-8674(00)00116-1.
Jeffrey KL, Camps M, Rommel C, Mackay CR: Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov. 2007, 6: 391-403. 10.1038/nrd2289.
Rhee SG, Bae YS, Lee SR, Kwon J: Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Science's STKE [Electronic Resource]: Signal Transduction Knowledge Environment. 2000, E1-
Meng TC, Fukada T, Tonks NK: Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Molecular Cell. 2002, 9: 387-399. 10.1016/S1097-2765(02)00445-8.
Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M: Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell. 2005, 120: 649-661. 10.1016/j.cell.2004.12.041.
Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Piao JH, Yagita H, Okumura K, Doi T, Nakano H: NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J. 2003, 22: 3898-3909. 10.1093/emboj/cdg379.
Baas AS, Berk BC: Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells. Circ Res. 1995, 77: 29-36.
Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ: A common mechanism of cellular death induced by bactericidal antibiotics. Cell. 2007, 130: 797-810. 10.1016/j.cell.2007.06.049.
Choi BM, Pae HO, Jang SI, Kim YM, Chung HT: Nitric oxide as a pro-apoptotic as well as anti-apoptotic modulator. J Biochem Mol Biol. 2002, 35: 116-126.
Shen HM, Liu ZG: JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic Biol Med. 2006, 40: 928-939. 10.1016/j.freeradbiomed.2005.10.056.
Ozben T: Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci. 2007, 96: 2181-2196. 10.1002/jps.20874.
Fiers W, Beyaert R, Declercq W, Vandenabeele P: More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene. 1999, 18: 7719-7730. 10.1038/sj.onc.1203249.
Rubinstein LV, Shoemaker RH, Paull KD, Simon RM, Tosini S, Skehan P, Scudiero DA, Monks A, Boyd MR: Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J Natl Cancer Inst. 1990, 82: 1113-1118. 10.1093/jnci/82.13.1113.
Zhang L, Gu J, Lin T, Huang X, Roth JA, Fang B: Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line. Gene Ther. 2002, 9: 1262-1270. 10.1038/sj.gt.3301797.
Kamata H, Hirata H: Redox regulation of cellular signalling. Cell Signal. 1999, 11: 1-14. 10.1016/S0898-6568(98)00037-0.
Shimizu T, Numata T, Okada Y: A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl(-) channel. Proc Natl Acad Sci USA. 2004, 101: 6770-6773. 10.1073/pnas.0401604101.
Ling YH, Liebes L, Zou Y, Perez-Soler R: Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells. J Biol Chem. 2003, 278: 33714-33723. 10.1074/jbc.M302559200.
Gunasekar PG, Borowitz JL, Isom GE: Cyanide-induced generation of oxidative species: involvement of nitric oxide synthase and cyclooxygenase-2. J Pharmacol Exp Ther. 1998, 285: 236-241.
Morris CR, Chen SC, Zhou L, Schopfer LM, Ding X, Mirvish SS: Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3. Nutr Cancer. 2004, 48: 54-63. 10.1207/s15327914nc4801_8.
Berndt G, Grosser N, Hoogstraate J, Schroder H: AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells. Eur J Pharm Sci. 2005, 25: 229-235.
Bassenge E, Sommer O, Schwemmer M, Bunger R: Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state. Am J Physiol Heart Circ Physiol. 2000, 279: H2431-H2438.
Guzman-Beltran S, Espada S, Orozco-Ibarra M, Pedraza-Chaverri J, Cuadrado A: Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress. Neurosci Lett. 2008, 447: 167-171. 10.1016/j.neulet.2008.09.079.
Rillema JA: Effect of NDGA, a lipoxygenase inhibitor, on prolactin actions in mouse mammary gland explants. Prostaglandins Leukot Med. 1984, 16: 89-94. 10.1016/0262-1746(84)90089-1.
Shimizu T, Wolfe LS: Arachidonic acid cascade and signal transduction. J Neurochem. 1990, 55: 1-15. 10.1111/j.1471-4159.1990.tb08813.x.
Smith WL: The eicosanoids and their biochemical mechanisms of action. Biochem J. 1989, 259: 315-324.
Bhosle SM, Pandey BN, Huilgol NG, Mishra KP, Bhosle SM, Pandey BN, Huilgol NG, Mishra KP: Membrane oxidative damage and apoptosis in cervical carcinoma cells of patients after radiation therapy. Methods Cell Sci. 2002, 24: 65-68. 10.1023/A:1024145931652.
Huang HL, Fang LW, Lu SP, Chou CK, Luh TY, Lai MZ: DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation. Oncogene. 2003, 22: 8168-8177. 10.1038/sj.onc.1206979.
Alexandre J, Hu Y, Lu W, Pelicano H, Huang P: Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species. Cancer Res. 2007, 67: 3512-3517. 10.1158/0008-5472.CAN-06-3914.
Furusawa S, Kimura E, Kisara S, Nakano S, Murata R, Tanaka Y, Sakaguchi S, Takayanagi M, Takayanagi Y, Sasaki K: Mechanism of resistance to oxidative stress in doxorubicin resistant cells. Biol Pharm Bull. 2001, 24: 474-479. 10.1248/bpb.24.474.
Kotamraju S, Kalivendi SV, Konorev E, Chitambar CR, Joseph J, Kalyanaraman B: Oxidant-induced iron signaling in Doxorubicin-mediated apoptosis. Methods Enzymol. 2004, 378: 362-382. full_text.
Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW: The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc Natl Acad Sci USA. 2001, 98: 10833-10838. 10.1073/pnas.191208598.
Simizu S, Takada M, Umezawa K, Imoto M: Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs. J Biol Chem. 1998, 273: 26900-26907. 10.1074/jbc.273.41.26900.
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ: Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science. 1997, 275: 1649-1652. 10.1126/science.275.5306.1649.
Maciag A, Anderson LM: Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis. Exp Lung Res. 2005, 31: 83-104. 10.1080/01902140490495048.
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM: Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature. 2002, 419: 316-321. 10.1038/nature01036.
Nogueira V, Park Y, Chen CC, Xu PZ, Chen ML, Tonic I, Unterman T, Hay N: Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell. 2008, 14: 458-470. 10.1016/j.ccr.2008.11.003.
Meng D, Shi X, Jiang BH, Fang J: Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. Free Radic Biol Med. 2007, 42: 1651-1660. 10.1016/j.freeradbiomed.2007.01.037.
Chen CH, Cheng TH, Lin H, Shih NL, Chen YL, Chen YS, Cheng CF, Lian WS, Meng TC, Chiu WT, Chen JJ: Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts. Mol Pharmacol. 2006, 69: 1347-1355. 10.1124/mol.105.017558.
Colavitti R, Pani G, Bedogni B, Anzevino R, Borrello S, Waltenberger J, Galeotti T: Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR. J Biol Chem. 2002, 277: 3101-3108. 10.1074/jbc.M107711200.
Benhar M, Dalyot I, Engelberg D, Levitzki A: Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol Cell Biol. 2001, 21: 6913-6926. 10.1128/MCB.21.20.6913-6926.2001.
Kyriakis JM, Avruch J: Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev. 2001, 81: 807-869.
Lewis TS, Shapiro PS, Ahn NG: Signal transduction through MAP kinase cascades. Cancer Res. 1998, 74: 49-139. full_text.
Shen HM, Pervaiz S: TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J. 2006, 20: 1589-1598. 10.1096/fj.05-5603rev.