Figure 6
From: Oxidative stress in NSC-741909-induced apoptosis of cancer cells
Effects of antioxidants on NSC-741909-induced JNK/c-Jun activation. (A) H460 cells were treated with 1 μM NSC-741909 in the presence or absence of various lipoxygenase inhibitors for 24 h. (B) H460 cells were treated with 1 μM NSC-741909 in the presence or absence of 10 mM of N-acetylcysteine (NAC) for 24 h. Whole-cell lysates were harvested for Western blot analysis of JNK and c-Jun activation.