Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, Reuben JM, Doyle GV, Allard WJ, Terstappen LW, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med. 2004;351(8):781–91.
Article
PubMed
CAS
Google Scholar
de Bono JS, Scher HI, Montgomery RB, Parker C, Miller MC, Tissing H, Doyle GV, Terstappen LW, Pienta KJ, Raghavan D. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin Cancer Res Off J Am Assoc Cancer Res. 2008;14(19):6302–9.
Article
CAS
Google Scholar
Okabe H, Tsunoda S, Hosogi H, Hisamori S, Tanaka E, Tanaka S, Sakai Y. Circulating tumor cells as an independent predictor of survival in advanced gastric cancer. Ann Surg Oncol. 2015;22(12):3954–61.
Article
PubMed
CAS
Google Scholar
Cohen SJ, Punt CJ, Iannotti N, Saidman BH, Sabbath KD, Gabrail NY, Picus J, Morse MA, Mitchell E, Miller MC, et al. Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer. Ann Oncol Off J Eur Soc Med Oncol. 2009;20(7):1223–9.
Article
CAS
Google Scholar
Normanno N, Rossi A, Morabito A, Signoriello S, Bevilacqua S, Di Maio M, Costanzo R, De Luca A, Montanino A, Gridelli C, et al. Prognostic value of circulating tumor cells’ reduction in patients with extensive small-cell lung cancer. Lung Cancer. 2014;85(2):314–9.
Article
PubMed
Google Scholar
Racila E, Euhus D, Weiss AJ, Rao C, McConnell J, Terstappen LW, Uhr JW. Detection and characterization of carcinoma cells in the blood. Proc Natl Acad Sci USA. 1998;95(8):4589–94.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zieglschmid V, Hollmann C, Bocher O. Detection of disseminated tumor cells in peripheral blood. Crit Rev Clin Lab Sci. 2005;42(2):155–96.
Article
PubMed
CAS
Google Scholar
Weissenstein U, Schumann A, Reif M, Link S, Toffol-Schmidt UD, Heusser P. Detection of circulating tumor cells in blood of metastatic breast cancer patients using a combination of cytokeratin and EpCAM antibodies. BMC Cancer. 2012;12:206.
Article
PubMed
PubMed Central
CAS
Google Scholar
Liu Z, Zhang W, Huang F, Feng H, Shu W, Xu X, Chen Y. High throughput capture of circulating tumor cells using an integrated microfluidic system. Biosens Bioelectron. 2013;47:113–9.
Article
PubMed
CAS
Google Scholar
Huang T, Jia CP, Jun Y, Sun WJ, Wang WT, Zhang HL, Cong H, Jing FX, Mao HJ, Jin QH, et al. Highly sensitive enumeration of circulating tumor cells in lung cancer patients using a size-based filtration microfluidic chip. Biosens Bioelectron. 2014;51:213–8.
Article
PubMed
CAS
Google Scholar
Fan X, Jia C, Yang J, Li G, Mao H, Jin Q, Zhao J. A microfluidic chip integrated with a high-density PDMS-based microfiltration membrane for rapid isolation and detection of circulating tumor cells. Biosens Bioelectron. 2015;71:380–6.
Article
PubMed
CAS
Google Scholar
Nwankire CE, Venkatanarayanan A, Glennon T, Keyes TE, Forster RJ, Ducree J. Label-free impedance detection of cancer cells from whole blood on an integrated centrifugal microfluidic platform. Biosens Bioelectron. 2015;68:382–9.
Article
PubMed
CAS
Google Scholar
Shen H, Yang J, Chen Z, Chen X, Wang L, Hu J, Ji F, Xie G, Feng W. A novel label-free and reusable electrochemical cytosensor for highly sensitive detection and specific collection of CTCs. Biosens Bioelectron. 2016;81:495–502.
Article
PubMed
CAS
Google Scholar
Kwak B, Lee J, Lee D, Lee K, Kwon O, Kang S, Kim Y. Selective isolation of magnetic nanoparticle-mediated heterogeneity subpopulation of circulating tumor cells using magnetic gradient based microfluidic system. Biosens Bioelectron. 2017;88:153–8.
Article
PubMed
CAS
Google Scholar
Warkiani ME, Khoo BL, Wu L, Tay AK, Bhagat AA, Han J, Lim CT. Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics. Nat Protoc. 2016;11(1):134–48.
Article
PubMed
CAS
Google Scholar
Saliba AE, Saias L, Psychari E, Minc N, Simon D, Bidard FC, Mathiot C, Pierga JY, Fraisier V, Salamero J, et al. Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays. Proc Natl Acad Sci USA. 2010;107(33):14524–9.
Article
PubMed
PubMed Central
Google Scholar
Jo SM, Lee JJ, Heu W, Kim HS. Nanotentacle-structured magnetic particles for efficient capture of circulating tumor cells. Small. 2015;11(16):1975–82.
Article
PubMed
CAS
Google Scholar
Liljefors M, Nilsson B, Fagerberg J, Ragnhammar P, Mellstedt H, Frodin JE. Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. Int J Oncol. 2005;26(6):1581–9.
PubMed
CAS
Google Scholar
Gorges TM, Tinhofer I, Drosch M, Rose L, Zollner TM, Krahn T, von Ahsen O. Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition. BMC Cancer. 2012;12:178.
Article
PubMed
PubMed Central
CAS
Google Scholar
Hosokawa M, Hayata T, Fukuda Y, Arakaki A, Yoshino T, Tanaka T, Matsunaga T. Size-selective microcavity array for rapid and efficient detection of circulating tumor cells. Anal Chem. 2010;82(15):6629–35.
Article
PubMed
CAS
Google Scholar
Zheng S, Lin H, Liu JQ, Balic M, Datar R, Cote RJ, Tai YC. Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells. J Chromatogr A. 2007;1162(2):154–61.
Article
PubMed
CAS
Google Scholar
Chen F, Wang S, Fang Y, Zheng L, Zhi X, Cheng B, Chen Y, Zhang C, Shi D, Song H, et al. Feasibility of a novel one-stop ISET device to capture CTCs and its clinical application. Oncotarget. 2017;8(2):3029–41.
PubMed
Google Scholar
Li Y, Gong J, Zhang Q, Lu Z, Gao J, Li Y, Cao Y, Shen L. Dynamic monitoring of circulating tumour cells to evaluate therapeutic efficacy in advanced gastric cancer. Br J Cancer. 2016;114(2):138–45.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zhou J, Ma X, Bi F, Liu M. Clinical significance of circulating tumor cells in gastric cancer patients. Oncotarget. 2017;8(15):25713–20.
PubMed
PubMed Central
Google Scholar
Matsusaka S, Chin K, Ogura M, Suenaga M, Shinozaki E, Mishima Y, Terui Y, Mizunuma N, Hatake K. Circulating tumor cells as a surrogate marker for determining response to chemotherapy in patients with advanced gastric cancer. Cancer Sci. 2010;101(4):1067–71.
Article
PubMed
CAS
Google Scholar
Dhar M, Wong J, Karimi A, Che J, Renier C, Matsumoto M, Triboulet M, Garon EB, Goldman JW, Rettig MB, et al. High efficiency vortex trapping of circulating tumor cells. Biomicrofluidics. 2015;9(6):064116.
Article
PubMed
PubMed Central
Google Scholar
Sobin LH, Gospodarowicz MK, Wittekind C. TNM Classification of Malignant Tumours. 7th ed. Oxford: Blackwell Publishing Ltd; 2010.
Google Scholar
Hsieh TH, Keh HJ. Boundary effects on electrophoresis of a colloidal cylinder with a nonuniform zeta potential distribution. J Colloid Interface Sci. 2007;315(1):343–54.
Article
PubMed
CAS
Google Scholar
Davison SM, Sharp KV. Transient simulations of the electrophoretic motion of a cylindrical particle through a 90° corner. Microfluid Nanofluid. 2008;4(5):409–18.
Article
Google Scholar
Zhao LY, Chen XL, Wang YG, Xin Y, Zhang WH, Wang YS, Chen XZ, Yang K, Liu K, Xue L, et al. A new predictive model combined of tumor size, lymph nodes count and lymphovascular invasion for survival prognosis in patients with lymph node-negative gastric cancer. Oncotarget. 2016;7(44):72300–10.
Article
PubMed
PubMed Central
Google Scholar
Lee JH, Kim MG, Jung MS, Kwon SJ. Prognostic significance of lymphovascular invasion in node-negative gastric cancer. World J Surg. 2015;39(3):732–9.
Article
PubMed
Google Scholar
Aurello P, Berardi G, Tierno SM, Rampioni Vinciguerra GL, Socciarelli F, Laracca GG, Giulitti D, Pilozzi E, Ramacciato G. Influence of perineural invasion in predicting overall survival and disease-free survival in patients with locally advanced gastric cancer. Am J Surg. 2017;213(4):748–53. https://doi.org/10.1016/j.amjsurg.2016.05.022.
Article
PubMed
Google Scholar
Selcukbiricik F, Tural D, Buyukunal E, Serdengecti S. Perineural invasion independent prognostic factors in patients with gastric cancer undergoing curative resection. Asian Pac J Cancer Prev APJCP. 2012;13(7):3149–52.
Article
PubMed
Google Scholar
Chang YS, di Tomaso E, McDonald DM, Jones R, Jain RK, Munn LL. Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci USA. 2000;97(26):14608–13.
Article
PubMed
PubMed Central
CAS
Google Scholar
De Giorgi U, Valero V, Rohren E, Mego M, Doyle GV, Miller MC, Ueno NT, Handy BC, Reuben JM, Macapinlac HA, et al. Circulating tumor cells and bone metastases as detected by FDG-PET/CT in patients with metastatic breast cancer. Ann Oncol Off J Eur Soc Med Oncol. 2010;21(1):33–9.
Article
Google Scholar
De Giorgi U, Mego M, Scarpi E, Giuliano M, Giordano A, Reuben JM, Valero V, Ueno NT, Hortobagyi GN, Cristofanilli M. Relationship between lymphocytopenia and circulating tumor cells as prognostic factors for overall survival in metastatic breast cancer. Clin Breast Cancer. 2012;12(4):264–9.
Article
PubMed
Google Scholar
Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature. 2008;454(7203):436–44.
Article
PubMed
CAS
Google Scholar
Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009;30(7):1073–81.
Article
PubMed
CAS
Google Scholar
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell. 2010;140(6):883–99.
Article
PubMed
PubMed Central
CAS
Google Scholar
Xu AM, Huang L, Zhu L, Wei ZJ. Significance of peripheral neutrophil-lymphocyte ratio among gastric cancer patients and construction of a treatment-predictive model: a study based on 1131 cases. Am J Cancer Res. 2014;4(2):189–95.
PubMed
PubMed Central
Google Scholar
Kim EY, Lee JW, Yoo HM, Park CH, Song KY. The platelet-to-lymphocyte ratio versus neutrophil-to-lymphocyte ratio: which is better as a prognostic factor in gastric cancer? Ann Surg Oncol. 2015;22(13):4363–70.
Article
PubMed
Google Scholar
Jenne CN, Urrutia R, Kubes P. Platelets: bridging hemostasis, inflammation, and immunity. Int J Lab Hematol. 2013;35(3):254–61.
Article
PubMed
CAS
Google Scholar
Labelle M, Begum S, Hynes RO. Platelets guide the formation of early metastatic niches. Proc Natl Acad Sci USA. 2014;111(30):E3053–61.
Article
PubMed
PubMed Central
CAS
Google Scholar
Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21(2):137–48.
Article
PubMed
CAS
Google Scholar
De Larco JE, Wuertz BR, Furcht LT. The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8. Clin Cancer Res Off J Am Assoc Cancer Res. 2004;10(15):4895–900.
Article
Google Scholar
Zhang X, Zhang W, Feng LJ. Prognostic significance of neutrophil lymphocyte ratio in patients with gastric cancer: a meta-analysis. PLoS ONE. 2014;9(11):e111906.
Article
PubMed
PubMed Central
CAS
Google Scholar
Xin-Ji Z, Yong-Gang L, Xiao-Jun S, Xiao-Wu C, Dong Z, Da-Jian Z. The prognostic role of neutrophils to lymphocytes ratio and platelet count in gastric cancer: a meta-analysis. Int J Surg. 2015;21:84–91.
Article
PubMed
Google Scholar
Xu Z, Xu W, Cheng H, Shen W, Ying J, Cheng F, Xu W. The prognostic role of the platelet-lymphocytes ratio in gastric cancer: a meta-analysis. PLoS ONE. 2016;11(9):e0163719.
Article
PubMed
PubMed Central
CAS
Google Scholar