Higuchi M, Fujii M: Distinct function of HTLV-1 Tax1 from HTLV-2 Tax2 contributes key roles to viral pathogenesis. Retrovirology. 2009, 6: 117-127. 10.1186/1742-4690-6-117.
Article
PubMed Central
PubMed
Google Scholar
De Thé G, Kazanji M: An HTLV-I/II vaccine: from animal models to clinical trials?. J Acquir Immune Defic Syndr Hum Retrovirol. 1996, 13 (Suppl 1): S191-198.
Article
PubMed
Google Scholar
Feuer G, Green PL: Comparative biology of human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2. Oncogene. 2005, 24: 5996-6004. 10.1038/sj.onc.1208971.
Article
PubMed Central
CAS
PubMed
Google Scholar
Franchini G: Molecular mechanisms of human T-cell leukemia/lymphotropic virus type I infection. Blood. 1995, 86: 3619-3639.
CAS
PubMed
Google Scholar
Richardson JH, Edwards AJ, Cruickshank JK, Rudge P, Dalgleish AG: In vivo cellular tropism of human T-cell leukemia virus type 1. J Virol. 1990, 64: 5682-5687.
PubMed Central
CAS
PubMed
Google Scholar
Casoli C, Cimarelli A, Bertazzoni U: Cellular tropism of human T-cell leukemia virus type II is enlarged to B lymphocytes in patients with high proviral load. Virology. 1995, 206: 1126-1128. 10.1006/viro.1995.1036.
Article
CAS
PubMed
Google Scholar
Lal RB, Owen SM, Rudolph DL, Dawson C, Prince H: In vivo cellular tropism of human T-lymphotropic virus type II is not restricted to CD8+ cells. Virology. 1995, 210: 441-447. 10.1006/viro.1995.1360.
Article
CAS
PubMed
Google Scholar
Hoffman PM, Dhib-Jalbut S, Mikovits JA, Robbins DS, Wolf AL, Bergey GK, Lohrey NC, Weislow OS, Ruscetti FW: Human T-cell leukemia virus type I infection of monocytes and microglial cells in primary human cultures. Proc Natl Acad Sci USA. 1992, 89: 11784-11788. 10.1073/pnas.89.24.11784.
Article
PubMed Central
CAS
PubMed
Google Scholar
Poiesz B, Ruscetti F, Gazdar A, Bunn P, Minna J, Gallo R: Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA. 1980, 77: 7415-7419. 10.1073/pnas.77.12.7415.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yoshida M, Miyoshi I, Hinuma Y: Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease. Proc Natl Acad Sci USA. 1982, 79: 2031-2035. 10.1073/pnas.79.6.2031.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gessain A, Barin F, Vernant J, Gout O, Maurs L, Calender A, de The G: Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet. 1985, 2: 407-410.
Article
CAS
PubMed
Google Scholar
Osame M, Usuku K, Izumu S, Ijichi N, Amitani H, Igata A, Matsumoto M, Tara M: HTLV-1 associated myelopathy, a new clinical entity. Lancet. 1986, 1: 1031-1032.
Article
CAS
PubMed
Google Scholar
Ross TM, Pettiford SM, Green PL: The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes. J Virol. 1996, 70: 5194-5202.
PubMed Central
CAS
PubMed
Google Scholar
Robek MD, Ratner L: Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone. J Virol. 1999, 73: 4856-65.
PubMed Central
CAS
PubMed
Google Scholar
Nerenberg M, Hinrichs SH, Reynolds RK, Khoury G, Jay G: The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice. Science. 1987, 237: 1324-1329. 10.1126/science.2888190.
Article
CAS
PubMed
Google Scholar
Hasegawa H, Sawa H, Lewis MJ, Orba Y, Sheehy N, Yamamoto Y, Ichinohe T, Tsunetsugu-Yokota Y, Katano H, Takahashi H, Matsuda J, Sata T, Kurata T, Nagashima K, Hall WW: Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I. Nat Med. 2006, 12: 466-472. 10.1038/nm1389.
Article
CAS
PubMed
Google Scholar
Matsuoka M, Jeang K-T: Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ, and therapy. Oncogene. 2011, 30: 1379-1389. 10.1038/onc.2010.537.
Article
PubMed Central
CAS
PubMed
Google Scholar
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA: Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Science. 1986, 16: 877-880.
Article
Google Scholar
Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC: HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Science. 1988, 23: 1652-1655.
Article
Google Scholar
Yoshida M: Discovery of HTLV-1, the first human retrovirus, its unique regulatory mechanisms, and insights into pathogenesis. Oncogene. 2005, 5: 5931-5937.
Article
Google Scholar
Casoli C, De Lerma Barbaro A, Pilotti E, Bertazzoni U, Tosi G, Accolla RS: The MHC class II transcriptional activator (CIITA) inhibits HTLV-2 viral replication by blocking the function of the viral transactivator Tax-2. Blood. 2004, 103: 995-1001.
Article
CAS
PubMed
Google Scholar
Tosi G, Pilotti E, Mortara L, De Lerma Barbaro A, Casoli C, Accolla RS: Inhibition of human T cell leukemia virus type 2 replication by the suppressive action of class II transactivator and nuclear factor Y. Proc Natl Acad Sci. 2006, 103: 12861-12866. 10.1073/pnas.0601589103.
Article
PubMed Central
CAS
PubMed
Google Scholar
Accolla RS, De Lerma Barbaro A, Mazza S, Casoli C, De Maria A, Tosi G: The MHC class II transactivator: prey and hunter in infectious diseases. Trends Immunol. 2001, 22: 560-563. 10.1016/S1471-4906(01)02003-8.
Article
CAS
PubMed
Google Scholar
Accolla RS, Mazza S, De Lerma Barbaro A, De Maria A, Tosi G: The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication. Eur J Immunol. 2002, 32: 2783-2791. 10.1002/1521-4141(2002010)32:10<2783::AID-IMMU2783>3.0.CO;2-E.
Article
CAS
PubMed
Google Scholar
Accolla RS, Jottrand-Bellomo M, Scarpellino L, Maffei A, Carra G, Guardiola J: aIr-1, a newly found locus on mouse chromosome 16 encoding a trans-acting activator factor for MHC class II gene expression. J Exp Med. 1986, 164: 369-374. 10.1084/jem.164.1.369.
Article
CAS
PubMed
Google Scholar
Steimle V, Otten LA, Zufferey M, Mach B: Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell. 1993, 75: 135-146.
Article
CAS
PubMed
Google Scholar
Reith W, LeibundGut-Landmann S, Waldburger JM: Regulation of MHC class II gene expression by the class II transactivator. Nat Rev Immunol. 2005, 5: 703-806.
Article
Google Scholar
Germain RN: MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell. 1994, 76: 287-299. 10.1016/0092-8674(94)90336-0.
Article
CAS
PubMed
Google Scholar
Caretti G, Cocchiarella F, Sidoli C, Villard J, Peretti M, Reith W, Mantovani R: Dissection of functional NF-Y-RFX cooperative interactions on the MHC class II Ea promoter. Mol Biol. 2000, 302: 539-552. 10.1006/jmbi.2000.4028.
Article
CAS
Google Scholar
De Sandro AM, Nagarajan UM, Boss JM: Associations and interactions between bare lymphocyte syndrome factors. Mol Cell Biol. 2000, 20: 6587-6599. 10.1128/MCB.20.17.6587-6599.2000.
Article
CAS
Google Scholar
Masternak K, Muhlethaler-Mottet A, Villard J, Zufferey M, Steimle V, Reith W: CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex. Genes Dev. 2000, 14: 1156-1166.
PubMed Central
CAS
PubMed
Google Scholar
Zhu XS, Linhoff M W, Li G, Chin K, Ting JPY: Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter. Mol Cell Biol. 2000, 20: 6051-6064. 10.1128/MCB.20.16.6051-6061.2000.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jabrane-Ferrat N, Nekrep N, Tosi G, Esserman L, Peterlin BM: Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor × (RFX) on DNA requires RFX5 dimers. Mol Cell Biol. 2002, 22: 5616-5625. 10.1128/MCB.22.15.5616-5625.2002.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jabrane-Ferrat N, Nekrep N, Tosi G, Peterlin BM: MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?. Int Immunol. 2003, 15: 467-475. 10.1093/intimm/dxg048.
Article
CAS
PubMed
Google Scholar
Kretsovali A, Agalioti T, Spilianakis C, Tzortzakaki E, Merika M, Papamatheakis J: Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol Cell Biol. 1998, 18: 6777-6783.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fontes JD, Kanazawa S, Jean D, Peterlin BM: Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes. Mol Cell Biol. 1999, 19: 941-947.
Article
PubMed Central
CAS
PubMed
Google Scholar
Spilianakis C, Papamatheakis J, Kretsovali A: Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Mol Cell Biol. 2000, 20: 8489-8498. 10.1128/MCB.20.22.8489-8498.2000.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kanazawa S, Takashi O, Peterlin BM: Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection. Immunity. 2000, 12: 61-70. 10.1016/S1074-7613(00)80159-4.
Article
CAS
PubMed
Google Scholar
Wei P, Garber ME, Fang SM, Fisher WH, Jones KA: A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell. 1998, 92: 451-462. 10.1016/S0092-8674(00)80939-3.
Article
CAS
PubMed
Google Scholar
Tosi G, Jabrane-Ferrat N, Peterlin BM: Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters. EMBO J. 2002, 21: 5467-5476. 10.1093/emboj/cdf557.
Article
PubMed Central
CAS
PubMed
Google Scholar
Harton JA, O'Connor W, Conti BJ, Linhoff MW, Ting JPY: Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation. Hum Immunol. 2002, 63: 588-601. 10.1016/S0198-8859(02)00400-7.
Article
CAS
PubMed
Google Scholar
Cressman DE, O'Connor WJ, Greer SF, Zhu XS, Ting JPY: Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator. J Immunol. 2001, 167: 3626-3634.
Article
CAS
PubMed
Google Scholar
Chevalier SA, Meertens L, Calattini S, Gessain A, Kiemer L, Mahieux R: Presence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein. Retrovirology. 2005, 70-79. 2
Meertens L, Chevalier S, Weil R, Gessain A, Mahieux R: A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution. J Biol Chem. 2004, 279: 43307-43320. 10.1074/jbc.M400497200.
Article
CAS
PubMed
Google Scholar
Avesani F, Romanelli MG, Turci M, Di Gennaro G, Sampaio C, Bidoia C, Bertazzoni U, Bex F: Association of HTLV Tax proteins with TAK1-binding protein 2 and RelA in calreticulin-containing cytoplasmic structures participates in Tax-mediated NF-κB activation. Virology. 2010, 408: 39-48. 10.1016/j.virol.2010.08.023.
Article
CAS
PubMed
Google Scholar
Alefantis T, Barmak K, Harhaj EW, Grant C, Wigdahl B: Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax. J Biol Chem. 2003, 278: 21814-21822. 10.1074/jbc.M211576200.
Article
CAS
PubMed
Google Scholar
Kahle J, Baake M, Doenecke D, Albig W: Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13. Mol Cell Biol. 2005, 5339-5354. 25
Google Scholar