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  1. Radiotherapy can induce tumor cell autophagy, which might impair the antitumoral effect. This study aims to investigate the effect of autophagy inhibition on the targeted radionuclide therapy (TRT) efficacy of 13...

    Authors: Xingyu Liu, Danni Li, Tianbao Ma, Xiu Luo, Ye Peng, Tao Wang, Changjing Zuo and Jianming Cai
    Citation: Journal of Translational Medicine 2024 22:156
  2. Tumor cells of diffuse-type gastric cancer (DGC) are discohesive and infiltrate into the stroma as single cells or small subgroups, so the stroma significantly impacts DGC progression. Cancer-associated fibrob...

    Authors: Dagyeong Lee, In-Hye Ham, Hye Jeong Oh, Dong Min Lee, Jung Hwan Yoon, Sang-Yong Son, Tae-Min Kim, Jae-Young Kim, Sang-Uk Han and Hoon Hur
    Citation: Journal of Translational Medicine 2024 22:154
  3. Skeletal system disease (SSD) is defined as a class of chronic disorders of skeletal system with poor prognosis and causes heavy economic burden. m6A, methylation at the N6 position of adenosine in RNA, is a r...

    Authors: Jianhui Liang, Qian Yi, Yang Liu, Jiachen Li, Zecheng Yang, Wei Sun and Weichao Sun
    Citation: Journal of Translational Medicine 2024 22:153
  4. This study aimed to assess the clinical application of the Artery Occlusion Image Score (AOIS), a new metric based on computed tomographic angiography (CTA) that reflects the severity of occlusive changes in t...

    Authors: Rui Xu, Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang and Li Jiang
    Citation: Journal of Translational Medicine 2024 22:152
  5. Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB has improved in the last years, more than 50% of hi...

    Authors: Mario Capasso, Chiara Brignole, Vito A. Lasorsa, Veronica Bensa, Sueva Cantalupo, Enrico Sebastiani, Alessandro Quattrone, Eleonora Ciampi, Marianna Avitabile, Angela R. Sementa, Katia Mazzocco, Barbara Cafferata, Gabriele Gaggero, Valerio G. Vellone, Michele Cilli, Enzo Calarco…
    Citation: Journal of Translational Medicine 2024 22:151
  6. The tumor-agnostic indication of immune checkpoint inhibitors to treat cancers with mismatch repair deficiency (dMMR)/microsatellite instability (MSI) increased the demand for such tests beyond Lynch syndrome....

    Authors: Maja L. Nádorvári, István Kenessey, András Kiss, Tamás Barbai, Janina Kulka, Erzsébet Rásó and József Tímár
    Citation: Journal of Translational Medicine 2024 22:150
  7. Hidradenitis suppurativa (HS), an inflammatory-based dermatological condition often associated with obesity, poses significant challenges in management. The very low-calorie ketogenic diet (VLCKD) has shown ef...

    Authors: Ludovica Verde, Sara Cacciapuoti, Giuseppina Caiazzo, Matteo Megna, Fabrizio Martora, Annarita Cavaliere, Maria Mattera, Maria Maisto, Gian Carlo Tenore, Annamaria Colao, Silvia Savastano, Giovanna Muscogiuri and Luigi Barrea
    Citation: Journal of Translational Medicine 2024 22:149
  8. Helicobacter pylori (H. pylori) is a major risk factor of gastric cancer (GC). The SUMO-activating enzyme SAE1(SUMO-activating enzyme subunit 1), which is indispensable for protein SUMOylation, involves in human ...

    Authors: Liu Shi, Jianfang Shangguan, Ying Lu, Jianfang Rong, Qinyu Yang, Yihan Yang, Chuan Xie and Xu Shu
    Citation: Journal of Translational Medicine 2024 22:148
  9. Excessive energy intake in modern society has led to an epidemic surge in metabolic diseases, such as obesity and type 2 diabetes, posing profound threats to women’s reproductive health. However, the precise i...

    Authors: Congcong Liu, Yunde Dou, Mengge Zhang, Shan Han, Shourui Hu, Yuxuan Li, Zhiheng Yu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Han Zhao and Yuqing Zhang
    Citation: Journal of Translational Medicine 2024 22:145
  10. Neoantigens have emerged as a promising area of focus in tumor immunotherapy, with several established strategies aiming to enhance their identification. Human leukocyte antigen class I molecules (HLA-I), whic...

    Authors: Fanghzou Wang, Zhenpeng Zhang, Mingsong Mao, Yudai Yang, Ping Xu and Shichun Lu
    Citation: Journal of Translational Medicine 2024 22:144
  11. Bone is a metabolically active tissue containing different cell types acting as endocrine targets and effectors. Further, bone is a dynamic depot for calcium, phosphorous and other essential minerals. The tiss...

    Authors: Amir Mohammad Malvandi, Esra Halilaj, Martina Faraldi, Laura Mangiavini, Simone Cristoni, Valerio Leoni and Giovanni Lombardi
    Citation: Journal of Translational Medicine 2024 22:143

    The Correction to this article has been published in Journal of Translational Medicine 2024 22:303

  12. Overweight is known to be an important risk factor for colorectal cancer (CRC), and the differences in intestinal flora among CRC patients with different BMI status have not been clearly defined. The purpose o...

    Authors: Yongqi Huang, Xiaoliang Huang, Zhen Wang, Fuhai He, Zigui Huang, Chuanbin Chen, Binzhe Tang, Mingjian Qin, Yongzhi Wu, Chenyan Long, Weizhong Tang, Xianwei Mo and Jungang Liu
    Citation: Journal of Translational Medicine 2024 22:142
  13. Cancer-testis antigens (CTAs) are tumor antigens that are normally expressed in the testes but are aberrantly expressed in several cancers. CTA overexpression drives the metastasis and progression of lung canc...

    Authors: R. J. Seager, Maria-Fernanda Senosain, Erik Van Roey, Shuang Gao, Paul DePietro, Mary K. Nesline, Durga Prasad Dash, Shengle Zhang, Heidi Ko, Stephanie B. Hastings, Kyle C. Strickland, Rebecca A. Previs, Taylor J. Jensen, Marcia Eisenberg, Brian J. Caveney, Eric A. Severson…
    Citation: Journal of Translational Medicine 2024 22:141
  14. Retinitis pigmentosa is the prevailing genetic cause of blindness in developed nations with no effective treatments. In the pursuit of unraveling the intricate dynamics underlying this complex disease, mechani...

    Authors: Marina Esteban-Medina, Carlos Loucera, Kinza Rian, Sheyla Velasco, Lorena Olivares-González, Regina Rodrigo, Joaquin Dopazo and Maria Peña-Chilet
    Citation: Journal of Translational Medicine 2024 22:139
  15. Chronic liver diseases constitute a major global public health burden, posing a substantial threat to patients’ daily lives and even survival due to the potential development of musculoskeletal disorders. Alth...

    Authors: Zhengjie Lu, Xuefei Li, Yongjian Qi, Bin Li and Liaobin Chen
    Citation: Journal of Translational Medicine 2024 22:138
  16. Pulmonary hypertension (PH) is a complex multifactorial vascular pathology characterized by an increased pulmonary arterial pressure, vasoconstriction, remodelling of the pulmonary vasculature, thrombosis in s...

    Authors: Ioana Karla Comarița, Gabriela Tanko, Iliuță Laurențiu Anghelache and Adriana Georgescu
    Citation: Journal of Translational Medicine 2024 22:137
  17. Advancements in data acquisition and computational methods are generating a large amount of heterogeneous biomedical data from diagnostic domains such as clinical imaging, pathology, and next-generation sequen...

    Authors: Valentina Brancato, Giuseppina Esposito, Luigi Coppola, Carlo Cavaliere, Peppino Mirabelli, Camilla Scapicchio, Rita Borgheresi, Emanuele Neri, Marco Salvatore and Marco Aiello
    Citation: Journal of Translational Medicine 2024 22:136
  18. Tumor mutational burden (TMB) has been demonstrated to predict the response to immune checkpoint inhibitors (ICIs) in various cancers. However, the role of TMB in head and neck squamous cell carcinoma (HNSCC) ...

    Authors: Juan P. Rodrigo, Mario Sánchez-Canteli, María Otero-Rosales, Pablo Martínez-Camblor, Francisco Hermida-Prado and Juana M. García-Pedrero
    Citation: Journal of Translational Medicine 2024 22:135
  19. Overweight and obesity are established risk factors for various types of cancers including colorectal cancer (CRC). However the underlying molecular mechanisms remain unclear. An in-depth understanding of the ...

    Authors: Guozhong Xiao, Yihui Zheng, Huaxian Chen, Minyi Luo, Chaoxin Yang, Donglin Ren, Pengfei Qin, Heng Zhang and Hongcheng Lin
    Citation: Journal of Translational Medicine 2024 22:134
  20. Oxaliplatin resistance usually leads to therapeutic failure and poor prognosis in colorectal cancer (CRC), while the underlying mechanisms are not yet fully understood. Metabolic reprogramming is strongly link...

    Authors: Yuting Huang, Szehoi Chan, Shuna Chen, Xueqi Liu, Miao Li, Liyuan Zheng, Zhaoxia Dong, Ziyi Yang, Zixuan Liu, Disheng Zhou, Xingding Zhang and Bo Zhang
    Citation: Journal of Translational Medicine 2024 22:133
  21. The current precision medicine relies on biomarkers, which are mainly obtained through next-generation sequencing (NGS). However, this model failed to find effective drugs for most cancer patients. This study ...

    Authors: Huan Yang, Xing Xiao, Leli Zeng, Haiteng Zeng, Yueyuan Zheng, Jingshu Wang, Guanghua Li, Weigang Dai, Yulong He, Suihai Wang, Jianjun Peng and Wei Chen
    Citation: Journal of Translational Medicine 2024 22:132
  22. The capability to gather heterogeneous data, alongside the increasing power of artificial intelligence to examine it, leading a revolution in harnessing multimodal data in the life sciences. However, most appr...

    Authors: Xiaobing Feng, Wen Shu, Mingya Li, Junyu Li, Junyao Xu and Min He
    Citation: Journal of Translational Medicine 2024 22:131
  23. Immune checkpoint blockades have been prized in circumventing and ablating the impediments posed by immunosuppressive receptors, reaching an exciting juncture to be an innovator in anticancer therapy beyond tr...

    Authors: Siyuan Wang, Jiaxin Wang, Yu Xia, Le Zhang, Yueqiang Jiang, Man Liu, Qinglei Gao and Cuntai Zhang
    Citation: Journal of Translational Medicine 2024 22:130
  24. DNMT3L is a crucial DNA methylation regulatory factor, yet its function and mechanism in hepatocellular carcinoma (HCC) remain poorly understood. Bioinformatics-based big data analysis has increasingly gained ...

    Authors: Xiaokai Yan, Yao Qi, Xinyue Yao, Nanjing Zhou, Xinxin Ye and Xing Chen
    Citation: Journal of Translational Medicine 2024 22:128
  25. Fertility preservation treatment is increasingly essential for patients with apical endometrial hyperplasia (AEH) and early endometrial cancer (EEC) worldwide. Complete regression (CR) is the main endpoint of ...

    Authors: Xingchen Li, Yiqin Wang, Jiaqi Wang, Yuan Fan and Jianliu Wang
    Citation: Journal of Translational Medicine 2024 22:127
  26. Glioblastoma multiforme (GBM) is the most common malignant primary brain cancer affecting the adult population. Median overall survival for GBM patients is poor (15 months), primarily due to high rates of tumo...

    Authors: Carla Bianca Luena Victorio, Wisna Novera, Arun Ganasarajah, Joanne Ong, Melisyaa Thomas, Jonas Wu, Hilary Si Yin Toh, Alfred Xuyang Sun, Eng Eong Ooi and Ann-Marie Chacko
    Citation: Journal of Translational Medicine 2024 22:126
  27. Previous studies have shown that changes in the microbial community of the female urogenital tract are associated with Human papillomavirus (HPV) infection. However, research on this association was mostly foc...

    Authors: Yong-Hong Dong, Yu-Hua Luo, Chen-Jian Liu, Wen-Yu Huang, Lin Feng, Xing-Yuan Zou, Jin-Yan Zhou and Xiao-Ran Li
    Citation: Journal of Translational Medicine 2024 22:125
  28. Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions associated with acute processes has been observed. We ai...

    Authors: Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón and Esther Roselló-Lletí
    Citation: Journal of Translational Medicine 2024 22:124
  29. Esophageal strictures significantly impair patient quality of life and present a therapeutic challenge, particularly due to the high recurrence post-ESD/EMR. Current treatments manage symptoms rather than addr...

    Authors: Fang Yang, Yiwei Hu, Zewen Shi, Mujie Liu, Kefeng Hu, Guoliang Ye, Qian Pang, Ruixia Hou, Keqi Tang and Yabin Zhu
    Citation: Journal of Translational Medicine 2024 22:123
  30. Emerging evidence suggests that Rho GTPases play a crucial role in tumorigenesis and metastasis, but their involvement in the tumor microenvironment (TME) and prognosis of hepatocellular carcinoma (HCC) is not...

    Authors: Qi Yang, Zewei Zhuo, Xinqi Qiu, Ruibang Luo, Kehang Guo, Huihuan Wu, Rui Jiang, Jingwei Li, Qizhou Lian, Pengfei Chen, Weihong Sha and Hao Chen
    Citation: Journal of Translational Medicine 2024 22:122
  31. Treatment responses to biologic agents vary between patients with moderate to severe psoriasis; while some patients achieve total skin clearance (TSC), a proportion of patients may only experience partial impr...

    Authors: Yuxiong Jiang, Dawei Huang, Qianyu Chen, Yingyuan Yu, Yifan Hu, Yu Wang, Rongfen Chen, Lingling Yao, Xiaoyuan Zhong, Luyang Kong, Qian Yu, Jiajing Lu, Ying Li and Yuling Shi
    Citation: Journal of Translational Medicine 2024 22:121
  32. One of the main factors for the osseointegration of dental implants is the development of an adequate soft tissue barrier, mainly composed by collagen, which protects the implant from bacterial development. Th...

    Authors: Alessia Belloni, Giulio Argentieri, Giulia Orilisi, Valentina Notarstefano, Elisabetta Giorgini, Gianmaria D’Addazio, Giovanna Orsini, Sergio Caputi and Bruna Sinjari
    Citation: Journal of Translational Medicine 2024 22:120
  33. Vitamin D (VD) is implicated in various health conditions, including colorectal cancer (CRC). To investigate potential relationships between pre-chemotherapy VD levels and the time-to-outcome in metastatic CRC...

    Authors: Alessandro Ottaiano, Maria Lucia Iacovino, Mariachiara Santorsola, Sergio Facchini, Domenico Iervolino, Francesco Perri, Guglielmo Nasti, Vincenzo Quagliariello, Nicola Maurea, Andrea Ronchi, Bianca Arianna Facchini, Alessia Bignucolo and Massimiliano Berretta
    Citation: Journal of Translational Medicine 2024 22:119
  34. Authors: Xing He, Yaorong Peng, Gui He, Huilin Ye, Liqiang Liu, Qixian Zhou, Juanyi Shi, Sha Fu, Jie Wang, Zhenyu Zhou and Wenbin Li
    Citation: Journal of Translational Medicine 2024 22:118

    The original article was published in Journal of Translational Medicine 2023 21:717

  35. Radioresistance is a primary factor contributing to the failure of rectal cancer treatment. Immune suppression plays a significant role in the development of radioresistance. We have investigated the potential...

    Authors: Junxian Liang, Limin Liao, Lang Xie, WenWen Tang, Xiang Yu, Yinghao Lu, Hongzhen Chen, Juanli Xu, Lei Sun, Huanmei Wu, Chunhui Cui and Yujing Tan
    Citation: Journal of Translational Medicine 2024 22:117
  36. Liver fibrosis contributes to significant morbidity and mortality in Western nations, primarily attributed to chronic hepatitis C virus (HCV) infection. Hypoxia and immune status have been reported to be signi...

    Authors: Chuwen Chen, Haozheng Cai, Junyi Shen, Xiaoyun Zhang, Wei Peng, Chuan Li, Haopeng Lv and Tianfu Wen
    Citation: Journal of Translational Medicine 2024 22:116
  37. Several evidence demonstrated that glucagon-like peptide 1 receptor agonists (GLP1-RAs) reduce the risk of dementia in type 2 diabetes patients by improving memory, learning, and overcoming cognitive impairmen...

    Authors: Rosaria Anna Fontanella, Puja Ghosh, Ada Pesapane, Fatemeh Taktaz, Armando Puocci, Martina Franzese, Maria Federica Feliciano, Giovanni Tortorella, Lucia Scisciola, Eduardo Sommella, Concetta Ambrosino, Giuseppe Paolisso and Michelangela Barbieri
    Citation: Journal of Translational Medicine 2024 22:114
  38. Ovarian cancer poses a serious threat to women's health. Due to the difficulty of early detection, most patients are diagnosed with advanced-stage disease or peritoneal metastasis. We found that LncRNA MEG3 is...

    Authors: Yan Li, Shenghan Lou, Jian Zhang, Shilu Zhao and Ge Lou
    Citation: Journal of Translational Medicine 2024 22:113
  39. Malignant progression is the major cause of poor prognosis in breast cancer (BC) patients. Plasma exosomal miRNAs have been reported to be involved in tumor progression, but their roles in BC remain unclear.

    Authors: Yao Li, Lei Fan, An Yan, Xiaotian Ren, Yanyang Zhao and Bin Hua
    Citation: Journal of Translational Medicine 2024 22:112
  40. Converging data have suggested that monocytic inflammation and C-reactive protein (CRP) are biologically intertwined processes and are involved in diabetogenesis. This study aimed to investigate the associatio...

    Authors: Dan Wu, Genyuan Chen, Yulong Lan, Shuohua Chen, Xiong Ding, Chiju Wei, Lois Balmer, Wei Wang, Shouling Wu and Wencan Xu
    Citation: Journal of Translational Medicine 2024 22:110
  41. Major depressive disorder (MDD) is a common mental illness that affects millions of people worldwide and imposes a heavy burden on individuals, families and society. Previous studies on MDD predominantly focus...

    Authors: Yinping Xie, Lijuan Chen, Leimin Wang, Tongou Liu, Yage Zheng, Lujia Si, Hailong Ge, Hong Xu, Ling Xiao and Gaohua Wang
    Citation: Journal of Translational Medicine 2024 22:109
  42. Patients with pancreatic ductal adenocarcinoma (PDCA) carrying impaired mismatch repair mechanisms seem to have an outcome advantage under treatment with conventional chemotherapy, whereas the role for the tum...

    Authors: Maria Cristina Sini, Maria Grazia Doro, Laura Frogheri, Angelo Zinellu, Panagiotis Paliogiannis, Alberto Porcu, Fabrizio Scognamillo, Daniele Delogu, Davide Adriano Santeufemia, Ivana Persico, Grazia Palomba, Giovanni Battista Maestrale, Antonio Cossu and Giuseppe Palmieri
    Citation: Journal of Translational Medicine 2024 22:108
  43. Several large cohort studies in cardiovascular disease (CVD) patients have shown an increased incidence of cancer. Previous studies in a myocardial infarction (MI) mouse model reported increased colon, breast,...

    Authors: Tanawat Attachaipanich, Siriporn C. Chattipakorn and Nipon Chattipakorn
    Citation: Journal of Translational Medicine 2024 22:105
  44. Prostate cancer (PCa) is one of the most common malignant tumors affecting the male genitourinary system. However, there is currently a lack of effective treatments for patients with advanced prostate cancer, ...

    Authors: Zefeng Wang, Zheng Chao, Qi Wang, Fan Zou, Tianbao Song, Lizhe Xu, Jinzhuo Ning and Fan Cheng
    Citation: Journal of Translational Medicine 2024 22:104

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