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  1. The relationship between muscle and prognosis, especially that between muscle distribution across different body parts, and the related prognosis is not well established.

    Authors: Chen-An Liu, Tong Liu, Yi-Zhong Ge, Meng-Meng Song, Guo-Tian Ruan, Shi-Qi Lin, Hai-Lun Xie, Jin-Yu Shi, Xin Zheng, Yue Chen, Liuyi Shen, Li Deng and Han-Ping Shi
    Citation: Journal of Translational Medicine 2023 21:154
  2. The interaction between the tumor-microenvironment (TME) and the cancer cells has emerged as a key player in colorectal cancer (CRC) metastasis. A small proportion of CRC cells which undergo epithelial-mesench...

    Authors: Jinsen Zheng, Rongzhang Dou, Xinyao Zhang, Bo Zhong, Chenggang Fang, Qian Xu, Ziyang Di, Sihao Huang, Zaihuan Lin, Jialin Song, Shuyi Wang and Bin Xiong
    Citation: Journal of Translational Medicine 2023 21:153
  3. At the end of December 2019, a novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) disease (COVID-19) has been identified in Wuhan, a central city in China, and then spread to every co...

    Authors: Mohammad Hadi Abbasian, Mohammadamin Mahmanzar, Karim Rahimian, Bahar Mahdavi, Samaneh Tokhanbigli, Bahman Moradi, Mahsa Mollapour Sisakht and Youping Deng
    Citation: Journal of Translational Medicine 2023 21:152
  4. Cancer-testis antigens (CTAs) are often expressed in tumor and testicular tissues but not in other normal tissues. To date, there has been no comprehensive study of the expression and clinical significance of ...

    Authors: Yu Miao, Yosuke Konno, Baojin Wang, Lin Zhu, Tianyue Zhai, Kei Ihira, Noriko Kobayashi, Hidemichi Watari, Xin Jin, Junming Yue, Peixin Dong and Mingyan Fang
    Citation: Journal of Translational Medicine 2023 21:151
  5. Periodontitis is the sixth most prevalent chronic disease globally and places significant burdens on societies and economies worldwide. Behavioral modification, risk factor control, coupled with cause-related ...

    Authors: Jianhan Ren, Melissa Rachel Fok, Yunfan Zhang, Bing Han and Yifan Lin
    Citation: Journal of Translational Medicine 2023 21:149
  6. Valtrate, a natural compound isolated from the root of Valeriana, exhibits antitumor activity in many cancers through different mechanisms. However, its efficacy for the treatment of glioblastoma (GBM), a tumor t...

    Authors: Xuemeng Liu, Yaotian Hu, Zhiyi Xue, Xun Zhang, Xiaofei Liu, Guowei Liu, Muzi Wen, Anjing Chen, Bin Huang, Xingang Li, Ning Yang and Jian Wang
    Citation: Journal of Translational Medicine 2023 21:147
  7. Kidney cancer undergoes a dramatic metabolic shift and has demonstrated responsiveness to immunotherapeutic intervention. However, metabolic classification and the associations between metabolic alterations an...

    Authors: Le Li, Zheng Chao, Un Waikeong, Jun Xiao, Yue Ge, Yanan Wang, Zezhong Xiong, Sheng Ma, Zhihua Wang, Zhiquan Hu and Xing Zeng
    Citation: Journal of Translational Medicine 2023 21:146
  8. The realization of the “microbiota–gut–brain” axis plays a critical role in neuropsychiatric disorders, particularly depression, is advancing rapidly. Matrine is a natural bioactive compound, which has been fo...

    Authors: Ming Zhang, Aoqiang Li, Qifang Yang, Jingyi Li, Lihua Zheng, Guannan Wang, Ying Sun, Yanxin Huang, Muqing Zhang, Zhenbo Song and Lei Liu
    Citation: Journal of Translational Medicine 2023 21:145
  9. Alpha-emitter radiopharmaceutical therapy (αRPT) has shown promising outcomes in metastatic disease. However, the short range of the alpha particles necessitates dosimetry on a near-cellular spatial scale. Cur...

    Authors: Remco Bastiaannet, Ioanna Liatsou, Robert F Hobbs and George Sgouros
    Citation: Journal of Translational Medicine 2023 21:144
  10. The left dorsolateral prefrontal cortex (DLPFC) is involved in early-phase manual dexterity skill acquisition when cognitive control processes, such as integration and complexity demands, are required. However...

    Authors: Akihiro Watanabe, Daisuke Sawamura, Hisato Nakazono, Yukina Tokikuni, Hiroshi Miura, Kazuhiro Sugawara, Kanako Fuyama, Harukazu Tohyama, Susumu Yoshida and Shinya Sakai
    Citation: Journal of Translational Medicine 2023 21:143
  11. Sepsis is a frequent complication in critically ill patients, is highly heterogeneous and is associated with high morbidity and mortality rates, especially in the elderly population. Utilizing RNA sequencing (...

    Authors: I-Chieh Chen, Hsin-Hua Chen, Yu-Han Jiang, Tzu-Hung Hsiao, Tai-Ming Ko and Wen-Cheng Chao
    Citation: Journal of Translational Medicine 2023 21:141
  12. Prognostic factors for initial response of advanced cutaneous squamous cell carcinoma to cemiplimab treatment are lacking. Il-6 has been found to affect immune cell populations which impact tumor development. ...

    Authors: Domenico Mallardo, Ester Simeone, Lucia Festino, Marilena Tuffanelli, Vito Vanella, Claudia Trojaniello, Maria Grazia Vitale, Margaret Ottaviano, Mariaelena Capone, Gabriele Madonna, Francesca Sparano, Eleonora Cioli, Luigi Scarpato, Marco Palla, Rossella Di Trolio, Paolo Meinardi…
    Citation: Journal of Translational Medicine 2023 21:140
  13. Exercise-related signaling Fndc5/irisin expresses in brain and acts as a crucial regulator of cognitive function, but its detailed roles in vascular dementia (VaD) are still unclear. Low intensity pulsed ultra...

    Authors: Degang Song, Xiaomin Chen, Na Zhou, Yi Yuan, Shuo Geng, Cong Zhang, Zhe Zhao, Xingran Wang, Xinran Bao, Xifa Lan and Xiangjian Zhang
    Citation: Journal of Translational Medicine 2023 21:139
  14. To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN).

    Authors: Sheng Cui, Xianying Fang, Hanbi Lee, Yoo Jin Shin, Eun-Sil Koh, Sungjin Chung, Hoon Suk Park, Sun Woo Lim, Kang In Lee, Jae Young Lee, Chul Woo Yang and Byung Ha Chung
    Citation: Journal of Translational Medicine 2023 21:138
  15. Studies focusing on the relationships of adiposity and body shape indices with reproductive factors have reported conflicting results. This study aimed to investigate the influence of reproductive factors on a...

    Authors: Mina Amiri, Maryam Mousavi, Fereidoun Azizi and Fahimeh Ramezani Tehrani
    Citation: Journal of Translational Medicine 2023 21:137
  16. Mitochondria represent a major source of reactive oxygen species (ROS) in cells, and the direct increase in ROS content is the primary cause of oxidative stress, which plays an important role in tumor prolifer...

    Authors: Shiao Tong, Minqi Xia, Yang Xu, Qian Sun, Liguo Ye, Fanen Yuan, Yixuan Wang, Jiayang Cai, Zhang Ye and Daofeng Tian
    Citation: Journal of Translational Medicine 2023 21:136
  17. Cognitive function is an important ability of the brain, but cognitive dysfunction can easily develop once the brain is injured in various neuropathological conditions or diseases. Photobiomodulation therapy i...

    Authors: Wei-tong Pan, Pan-miao Liu, Daqing Ma and Jian-jun Yang
    Citation: Journal of Translational Medicine 2023 21:135
  18. Radiotherapy resistance is the main cause of treatment failure in nasopharyngeal carcinoma (NPC), which leads to poor prognosis. It is urgent to elucidate the molecular mechanisms underlying radiotherapy resis...

    Authors: Enni Chen, Jiajia Huang, Miao Chen, Jiawei Wu, Puyun Ouyang, Xiaonan Wang, Dingbo Shi, Zhiqiao Liu, Wancui Zhu, Haohui Sun, Shanshan Yang, Baoyu Zhang, Wuguo Deng, Huijuan Qiu and Fangyun Xie
    Citation: Journal of Translational Medicine 2023 21:134
  19. Neovascular age-related macular degeneration (nAMD) is a major cause of visual impairment and blindness. Anti-vascular endothelial growth factor (VEGF) agents, such as ranibizumab, bevacizumab, aflibercept, br...

    Authors: Levon M. Khachigian, Gerald Liew, Kelvin Y. C. Teo, Tien Y. Wong and Paul Mitchell
    Citation: Journal of Translational Medicine 2023 21:133
  20. Osteosarcoma is the most common malignant tumor in bone and its prognosis has reached a plateau in the past few decades. Recently, metabolic reprogramming has attracted increasing attention in the field of can...

    Authors: Gaohong Sheng, Yuan Gao, Qing Ding, Ruizhuo Zhang, Tianqi Wang, Shaoze Jing, Hongqi Zhao, Tian Ma, Hua Wu and Yong Yang
    Citation: Journal of Translational Medicine 2023 21:132
  21. 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) identifies carotid plaque inflammation and predicts stroke recurrence.

    Authors: Eduardo Garcia, Pol Camps-Renom, Núria Puig, Alejandro Fernández-Leon, Ana Aguilera-Simón, Aleyda Benitez-Amaro, Arnau Solé, David Vilades, José Luis Sanchez-Quesada, Joan Martí-Fàbregas, Elena Jiménez-Xarrié, Sonia Benitez and Vicenta Llorente-Cortés
    Citation: Journal of Translational Medicine 2023 21:131
  22. The incidence of bladder cancer (BCa) is approximately four times higher in men than in women. To develop effective BCa treatments, there is an urgent need to understand the differences in the BCa control mech...

    Authors: Jaekwon Seok, Hee Jeong Kwak, Yeonjoo Kwak, Moonjung Lee, Kyoung Sik Park, Aram Kim and Ssang-Goo Cho
    Citation: Journal of Translational Medicine 2023 21:129
  23. Obesity is accompanied by hormonal, inflammatory and endothelial alterations. These alterations induce a stimulation of several other mechanisms that contribute to the hypertensive state and to increase the ca...

    Authors: Luigi Barrea, Ludovica Verde, Pasquale Santangeli, Stefania Lucà, Annamaria Docimo, Silvia Savastano, Annamaria Colao and Giovanna Muscogiuri
    Citation: Journal of Translational Medicine 2023 21:128
  24. Osteoporosis is highly polygenic and heritable, with heritability ranging from 50 to 80%; most inherited susceptibility is associated with the cumulative effect of many common genetic variants. However, existi...

    Authors: Qing Wu and Jongyun Jung
    Citation: Journal of Translational Medicine 2023 21:127
  25. Gut mycobiota plays a crucial role in benign liver diseases; however, its correlation with hepatocellular carcinoma (HCC) remains elusive. This study aimed to elucidate fungal differences in patients with HCC-...

    Authors: Lilong Zhang, Chen Chen, Dongqi Chai, Chunlei Li, Zhendong Qiu, Tianrui Kuang, Li Liu, Wenhong Deng and Weixing Wang
    Citation: Journal of Translational Medicine 2023 21:126
  26. Histone deacetylases (HDAC) contribute to oncogenic program, pointing to their inhibitors as a potential strategy against cancers. We, thus, studied the mechanism of HDAC inhibitor ITF2357 in resistance of mut...

    Authors: Jian Cui, Fei Xu, Wei Bai, Tiantian Zhao, Junbo Hong and Wei Zuo
    Citation: Journal of Translational Medicine 2023 21:125
  27. Muscle-invasive urothelial bladder cancer (MIBC) is associated with limited response rates to systemic therapy, risk of recurrence and death. Tumor infiltrating immune cells have been associated with outcome a...

    Authors: Florestan J. Koll, Severine Banek, Luis Kluth, Jens Köllermann, Katrin Bankov, Felix K.-H. Chun, Peter J. Wild, Andreas Weigert and Henning Reis
    Citation: Journal of Translational Medicine 2023 21:124
  28. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has unpredictable manifestations of coronavirus disease (COVID-19) and variable clinical course with some patients being asymptom...

    Authors: Anna Lucia Tornesello, Chiara Botti, Alberto Micillo, Francesco Labonia, Sergio Arpino, Maria Antonietta Isgrò, Serena Meola, Luigi Russo, Ernesta Cavalcanti, Silvia Sale, Carmine Nicastro, Luigi Atripaldi, Noemy Starita, Andrea Cerasuolo, Ulf Reimer, Pavlo Holenya…
    Citation: Journal of Translational Medicine 2023 21:123
  29. Malfunction of astrocytes is implicated as one of the pathological factors of ALS. Thus, intrathecal injection of healthy astrocytes in ALS can potentially compensate for the diseased astrocytes. AstroRx® is a...

    Authors: Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Slutsky, Judith Chebath, Graciela Kuperstein, Elena Estrin, Tamir Ben-Hur, Arik Hasson, Kfir Molakandov, Tehila Sonnenfeld, Yafit Stark, Ariel Revel, Michel Revel…
    Citation: Journal of Translational Medicine 2023 21:122
  30. Liver metastasis is the leading cause of death in patients with colorectal cancer (CRC). Surgical resection of the liver metastases increases the incidence of long-term survival in patients with colorectal liv...

    Authors: Xiangdong Li, Ziyi Wang, Chenyu Jiao, Yu Zhang, Nan Xia, Wenjie Yu, Xuejiao Chen, Likalamu Pascalia Wikana, Yue Liu, Linfeng Sun, Minhao Chen, Yuhao Xiao, Yuhua Shi, Sheng Han and Liyong Pu
    Citation: Journal of Translational Medicine 2023 21:121
  31. Metastasis is the predominant cause of mortality in patients with breast cancer. Long noncoding RNAs (lncRNAs) have been shown to drive important phenotypes in tumors, including invasion and metastasis. Howeve...

    Authors: Rong Guo, Yonghui Su, Qi Zhang, Bingqiu Xiu, Sheng Huang, Weiru Chi, Liyi Zhang, Lun Li, Jianjing Hou, Jia Wang, Jiajian Chen, Yayun Chi, Jingyan Xue and Jiong Wu
    Citation: Journal of Translational Medicine 2023 21:120
  32. Ki-67 labeling index (LI) is an important indicator of tumor cell proliferation in glioma, which can only be obtained by postoperative biopsy at present. This study aimed to explore the correlation between Ki-...

    Authors: Ningfang Du, Weiquan Shu, Kefeng Li, Yao Deng, Xinxin Xu, Yao Ye, Feng Tang, Renling Mao, Guangwu Lin, Shihong Li and Xuhao Fang
    Citation: Journal of Translational Medicine 2023 21:119
  33. Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale causing emotional, physical, and financial strains on individuals, families, and health care systems. Despite being the se...

    Authors: Siobhan Connal, James M. Cameron, Alexandra Sala, Paul M. Brennan, David S. Palmer, Joshua D. Palmer, Haley Perlow and Matthew J. Baker
    Citation: Journal of Translational Medicine 2023 21:118
  34. Gut dysbacteriosis has been reported as one of the etiologies for irritable bowel syndrome (IBS). However, the association between gut microbiota and IBS is still inconclusive.

    Authors: Han Chen, Rong Ou, Nana Tang, Wei Su, Ruoyun Yang, Xin Yu, Guoxin Zhang, Jianhua Jiao and Xiaoying Zhou
    Citation: Journal of Translational Medicine 2023 21:117
  35. Computed tomographies (CT) are useful for identifying muscle loss in non-small lung cancer (NSCLC) cachectic patients. However, we lack consensus on the best cutoff point for pectoralis muscle loss. We aimed t...

    Authors: Sarah Santiloni Cury, Diogo de Moraes, Jakeline Santos Oliveira, Paula Paccielli Freire, Patricia Pintor dos Reis, Miguel Luiz Batista Jr, Érica Nishida Hasimoto and Robson Francisco Carvalho
    Citation: Journal of Translational Medicine 2023 21:116
  36. Spermatogenesis associated serine rich 2 like (SPATS2L) was highly expressed in homoharringtonine (HHT) resistant acute myeloid leukemia (AML) cell lines. However, its role is little known in AML. The present ...

    Authors: Fenglin Li, Wenle Ye, Yiyi Yao, Wenwen Wei, Xiangjie Lin, Haihui Zhuang, Chenying Li, Xia Li, Qing Ling, Chao Hu, Xin Huang, Yu Qian, Shihui Mao, Jiansong Huang, Ying Lu and Jie Jin
    Citation: Journal of Translational Medicine 2023 21:115
  37. Cell–cell communications of various cell populations within tumor microenvironment play an essential role in primary tumor growth, metastasis evolution, and immune escape. Nevertheless, comprehensive investiga...

    Authors: Liu-xun Chen, Shen-jie Zeng, Xv-dong Liu, Hai-bin Tang, Jia-wu Wang and Qing Jiang
    Citation: Journal of Translational Medicine 2023 21:113
  38. Myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) is a complex, heterogenous disease. It has been suggested that subgroups of people with ME/CFS exist, displaying a specific cluster of symptoms. In...

    Authors: Anouk W. Vaes, Maarten Van Herck, Qichen Deng, Jeannet M. Delbressine, Leonard A. Jason and Martijn A. Spruit
    Citation: Journal of Translational Medicine 2023 21:112
  39. Fibroblast growth factor receptor 3 is known as a favorable aim in vast range of cancers, particularly in bladder cancer treatment. Pharmacophore and QSAR modeling approaches are broadly utilized for developin...

    Authors: Mahmoud Ganji, Shohreh Bakhshi, Alireza Shoari and Reza Ahangari Cohan
    Citation: Journal of Translational Medicine 2023 21:111
  40. Preclinical evidence from us and others demonstrates that the anticancer effects of cyclin-dependent kinase 4/6 (CDK4/6) inhibitors can be enhanced with focal radiation therapy (RT), but only when RT is delive...

    Authors: Vanessa Klapp, Aitziber Buqué, Norma Bloy, Ai Sato, Takahiro Yamazaki, Xi Kathy Zhou, Silvia C. Formenti, Lorenzo Galluzzi and Giulia Petroni
    Citation: Journal of Translational Medicine 2023 21:110
  41. Inadequate immunity caused by poor immune surveillance leads to tumorigenesis, while excessive immunity due to breakdown of immune tolerance causes autoimmune genesis. Although the function of immunity during ...

    Authors: Yuan Sui, Shuping Li, Xue-Qi Fu, Zhizhuang Joe Zhao and Shu Xing
    Citation: Journal of Translational Medicine 2023 21:109
  42. The prognosis of B-cell acute lymphoblastic leukemia (B-ALL) has improved significantly with current first-line therapy, although the recurrence of B-ALL is still a problem. Toll-like receptor 9 (TLR9) agonist...

    Authors: Ling Bai, Lei Zhou, Wei Han, Jingtao Chen, Xiaoyi Gu, Zheng Hu, Yongguang Yang, Wei Li, Xiaoying Zhang, Chao Niu, Yongchong Chen, Hui Li and Jiuwei Cui
    Citation: Journal of Translational Medicine 2023 21:108
  43. The incidence and mortality rate of gastrointestinal cancers are high worldwide. Increasing studies have illustrated that the occurrence, progression, metastasis and prognosis of cancers are intimately linked ...

    Authors: Weili Liu, Yuan Gao, Hua Li, Xinxing Wang, Min Jin, Zhiqiang Shen, Dong Yang, Xuelian Zhang, Zilin Wei, Zhaoli Chen and Junwen Li
    Citation: Journal of Translational Medicine 2023 21:107
  44. The Bacillus Calmette-Guérin (BCG) vaccine was discovered a century ago and has since been clinically applicable. BCG can not only be used for the prevention of tuberculosis, but also has a non-specific protec...

    Authors: Jingjing Chen, Li Gao, Xinya Wu, Yuxin Fan, Meixiao Liu, Li Peng, Jieqin Song, Bingxue Li, Aihua Liu and Fukai Bao
    Citation: Journal of Translational Medicine 2023 21:106
  45. The role of microRNA (miRNA) in modulating the function of cancer stem cells through diverse signaling pathway has been evidenced. We here identified a role of microRNA (miRNA) family, specifically miR-148/152...

    Authors: Xiaoying Li, Lin Li and Jiangying Wu
    Citation: Journal of Translational Medicine 2023 21:105
  46. Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospi...

    Authors: Fan Shuen Tseng, Joel Qi Xuan Foo, Aaron Shengting Mai and Eng-King Tan
    Citation: Journal of Translational Medicine 2023 21:104

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