Skip to main content

Articles

Page 5 of 98

  1. Inflammation and oxidative stress form a vicious circle in atherosclerosis. Oxidative stress can have detrimental effects on T cells. A unique subset of CD4+ T cells, known as regulatory T (Treg) cells, has been ...

    Authors: Anna K. Lundberg, Rosanna W. S. Chung, Louise Zeijlon, Gustav Fernström and Lena Jonasson

    Citation: Journal of Translational Medicine 2021 19:241

    Content type: Research

    Published on:

  2. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Iman Osman, Paolo Cotzia, Una Moran, Douglas Donnelly, Carolina Arguelles-Grande, Sandra Mendoza and Andre Moreira

    Citation: Journal of Translational Medicine 2021 19:240

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2020 18:219

  3. Improved understanding of tumor immunology has enabled the development of therapies that harness the immune system and prevent immune escape. Numerous clinical trials and real-world experience has provided evi...

    Authors: Paolo A. Ascierto, Carlo Bifulco, Fortunato Ciardiello, Sandra Demaria, Leisha A. Emens, Robert Ferris, Silvia C. Formenti, Jerome Galon, Samir N. Khleif, Tomas Kirchhoff, Jennifer McQuade, Kunle Odunsi, Akash Patnaik, Chrystal M. Paulos, Janis M. Taube, John Timmerman…

    Citation: Journal of Translational Medicine 2021 19:238

    Content type: Meeting report

    Published on:

  4. Recently, increased interleukin (IL)-24 expression has been demonstrated in the colon biopsies of adult patients with inflammatory bowel disease (IBD). However, the role of IL-24 in the pathomechanism of IBD i...

    Authors: Anna Ónody, Apor Veres-Székely, Domonkos Pap, Réka Rokonay, Beáta Szebeni, Erna Sziksz, Franz Oswald, Gábor Veres, Áron Cseh, Attila J. Szabó and Ádám Vannay

    Citation: Journal of Translational Medicine 2021 19:237

    Content type: Research

    Published on:

  5. To investigate the performance of diffusion-weighted (DW) MRI with mono-, bi- and stretched-exponential models in predicting pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) for breast can...

    Authors: Shiteng Suo, Yan Yin, Xiaochuan Geng, Dandan Zhang, Jia Hua, Fang Cheng, Jie Chen, Zhiguo Zhuang, Mengqiu Cao and Jianrong Xu

    Citation: Journal of Translational Medicine 2021 19:236

    Content type: Research

    Published on:

  6. The hallmark of non-alcoholic fatty liver disease (NAFLD) is the excessive hepatic lipid accumulation. Currently, no pharmacotherapy exists for NAFLD. However, the glucagon-like peptide-1 receptor agonists hav...

    Authors: Khaoula Errafii, Neyla S. Al-Akl, Olfa Khalifa and Abdelilah Arredouani

    Citation: Journal of Translational Medicine 2021 19:235

    Content type: Research

    Published on:

  7. Adipose cell-free derivatives have been recently gaining attention as potential therapeutic agents for various human diseases. In this context, mesenchymal stromal/stem cells (MSCs), adipocyte mesenchymal stem...

    Authors: Loubna Mazini, Luc Rochette and Gabriel Malka

    Citation: Journal of Translational Medicine 2021 19:234

    Content type: Commentary

    Published on:

  8. The transcriptomic signature has not been fully elucidated in PV, as well as mRNA markers for clinical variables (thrombosis, leukemic transformation, survival, etc.). We attempted to reveal and validate cruci...

    Authors: Chao Guo, Ya-yue Gao, Qian-qian Ju, Min Wang, Chun-xia Zhang, Ming Gong and Zhen-ling Li

    Citation: Journal of Translational Medicine 2021 19:233

    Content type: Research

    Published on:

  9. Malignant pleural mesothelioma (MPM) is a rare and aggressive tumour. For patients with inoperable disease, few treatment options are available after first line chemotherapy. The combination of ipilimumab and ...

    Authors: Vilde Drageset Haakensen, Anna K. Nowak, Espen Basmo Ellingsen, Saima Jamil Farooqi, Maria Moksnes Bjaanæs, Henrik Horndalsveen, Tine Mcculloch, Oscar Grundberg, Susana M. Cedres and Åslaug Helland

    Citation: Journal of Translational Medicine 2021 19:232

    Content type: Protocol

    Published on:

  10. Intratumour heterogeneous gene expression among cancer and cancer stem cells (CSCs) can cause failure of current targeted therapies because each drug aims to target the function of a single gene. Long mononucl...

    Authors: Narumol Bhummaphan, Piyapat Pin-on, Preeyaporn Plaimee Phiboonchaiyanan, Jirattha Siriluksana, Chatchawit Aporntewan, Pithi Chanvorachote and Apiwat Mutirangura

    Citation: Journal of Translational Medicine 2021 19:231

    Content type: Research

    Published on:

  11. Infections are a major disease burden worldwide. While they are caused by external pathogens, host genetics also plays a part in susceptibility to infections. Past studies have reported diverse associations be...

    Authors: Ron Nudel, Rosa Lundbye Allesøe, Wesley K. Thompson, Thomas Werge, Simon Rasmussen and Michael E. Benros

    Citation: Journal of Translational Medicine 2021 19:230

    Content type: Research

    Published on:

  12. There is growing evidence discussing the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). We performed this study to explore the impact of exosomal lncRNA urothelial cancer-associated 1 (UCA1) i...

    Authors: Zhihui Gao, Qianqing Wang, Mei Ji, Xiangcui Guo, Li Li and Xiaoke Su

    Citation: Journal of Translational Medicine 2021 19:229

    Content type: Research

    Published on:

  13. The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles...

    Authors: Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang, Ming Gong and Zhen-ling Li

    Citation: Journal of Translational Medicine 2021 19:228

    Content type: Research

    Published on:

  14. Alcohol consumption is one of the modifiable risk factors for intracerebral hemorrhage, which accounts for approximately 10–20% of all strokes worldwide. We evaluated the association of stroke with genetic pol...

    Authors: Chun-Hsiang Lin, Oswald Ndi Nfor, Chien-Chang Ho, Shu-Yi Hsu, Disline Manli Tantoh, Yi-Chia Liaw, Mochly-Rosen Daria, Che-Hong Chen and Yung-Po Liaw

    Citation: Journal of Translational Medicine 2021 19:227

    Content type: Research

    Published on:

  15. Circular RNAs (circRNAs) are a new class of noncoding RNAs that have gained increased attention in human tumor research. However, the identification and function of circRNAs are largely unknown in the context ...

    Authors: Zhijie Dong, Zhaoyu Liu, Min Liang, Jinhui Pan, Mingzhen Lin, Hai Lin, Yuanwei Luo, Xinke Zhou and Wenxia Yao

    Citation: Journal of Translational Medicine 2021 19:226

    Content type: Research

    Published on:

  16. Transfusion-related immunomodulation (TRIM) can be caused by exosomes, in which case, microRNAs (miRNAs) are one critical factor impacting exosome behavior. This study aims to investigate and analyze the expre...

    Authors: Yujie Kong, Xue Tian, Rui He, Chenyue Li, Haixia Xu, Li Tian and Zhong Liu

    Citation: Journal of Translational Medicine 2021 19:225

    Content type: Research

    Published on:

  17. It has been established that microRNA (miR)-449a is anti-tumorigenic in cancers, including lung cancer. Therefore, this study further explored miR-449a-mediated mechanism in lung cancer, mainly focusing on lys...

    Authors: Shan Hu, Peng Cao, Kangle Kong, Peng Han, Yu Deng, Fan Li and Bo Zhao

    Citation: Journal of Translational Medicine 2021 19:224

    Content type: Research

    Published on:

  18. Experimental autoimmune encephalomyelitis (EAE) is a model for inflammatory demyelinating diseases of the central nervous system (CNS), a group of autoimmune diseases characterized by inflammatory infiltration...

    Authors: Yishu Wang, Chong Xie, Yaying Song, Weiwei Xiang, Jing Peng, Lu Han, Jie Ding and Yangtai Guan

    Citation: Journal of Translational Medicine 2021 19:223

    Content type: Research

    Published on:

  19. The main limitation of current immune checkpoint inhibitors (ICIs) in the treatment of cervical cancer comes from the fact that it benefits only a minority of patients. The study aims to develop a classificati...

    Authors: Yimin Li, Shun Lu, Shubin Wang, Xinhao Peng and Jinyi Lang

    Citation: Journal of Translational Medicine 2021 19:222

    Content type: Research

    Published on:

  20. Until now, epidemiological evidence regarding the association between vitamin C intake (both diet and supplements) and Parkinson’s disease (PD) remains inconsistent. Hence, it is necessary to establish the cau...

    Authors: Haijie Liu, Yan Zhang, Haihua Zhang, Longcai Wang, Tao Wang, Zhifa Han, Liyong Wu and Guiyou Liu

    Citation: Journal of Translational Medicine 2021 19:221

    Content type: Research

    Published on:

  21. The phytocannabinoid cannabidiol (CBD) exhibits anxiolytic activity and has been promoted as a potential treatment for post-traumatic stress disorders. How does CBD interact with the brain to alter behavior? W...

    Authors: Aymen H. Sadaka, Ana G. Ozuna, Richard J. Ortiz, Praveen Kulkarni, Clare T. Johnson, Heather B. Bradshaw, Bruce S. Cushing, Ai-Ling Li, Andrea G. Hohmann and Craig F. Ferris

    Citation: Journal of Translational Medicine 2021 19:220

    Content type: Research

    Published on:

  22. Generally, cancer cells undergo metabolic reprogramming to adapt to energetic and biosynthetic requirements that support their uncontrolled proliferation. However, the mutual relationship between two critical ...

    Authors: Guoshu Bi, Yunyi Bian, Jiaqi Liang, Jiacheng Yin, Runmei Li, Mengnan Zhao, Yiwei Huang, Tao Lu, Cheng Zhan, Hong Fan and Qun Wang

    Citation: Journal of Translational Medicine 2021 19:219

    Content type: Research

    Published on:

  23. Post-translational modification (PTM) is a biological process that alters proteins and is therefore involved in the regulation of various cellular activities and pathogenesis. Protein phosphorylation is an ess...

    Authors: Salma Jamal, Waseem Ali, Priya Nagpal, Abhinav Grover and Sonam Grover

    Citation: Journal of Translational Medicine 2021 19:218

    Content type: Research

    Published on:

  24. Citation: Journal of Translational Medicine 2021 19:217

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2021 19:50

  25. Eukaryotic translation initiation factor 6 (eIF6) has a crucial function in the maturation of 60S ribosomal subunits, and it controls the initiation of protein translation. Although emerging studies indicate t...

    Authors: Liping Sun, Shuguang Liu, Xiaopai Wang, Xuefeng Zheng, Ya Chen and Hong Shen

    Citation: Journal of Translational Medicine 2021 19:216

    Content type: Research

    Published on:

  26. The fecal microbiota in pancreatic ductal adenocarcinoma (PDAC) and in autoimmune pancreatitis (AIP) patients remains largely unknown. We aimed to characterize the fecal microbiota in patients with PDAC and AI...

    Authors: Wenli Zhou, De Zhang, Zhengpeng Li, Huiqing Jiang, Jingnan Li, Rongrong Ren, Xuefeng Gao, Jianfeng Li, Xin Wang, Weifeng Wang and Yunsheng Yang

    Citation: Journal of Translational Medicine 2021 19:215

    Content type: Research

    Published on:

  27. Mitochondria are essential organelles that provide energy for cellular functions, participate in cellular signaling and growth, and facilitate cell death. Based on their multifactorial roles, mitochondria are ...

    Authors: Kei Hayashida, Ryosuke Takegawa, Muhammad Shoaib, Tomoaki Aoki, Rishabh C. Choudhary, Cyrus E. Kuschner, Mitsuaki Nishikimi, Santiago J. Miyara, Daniel M. Rolston, Sara Guevara, Junhwan Kim, Koichiro Shinozaki, Ernesto P. Molmenti and Lance B. Becker

    Citation: Journal of Translational Medicine 2021 19:214

    Content type: Review

    Published on:

  28. Glioma is an extremely aggressive malignant neoplasm of the central nervous system. MicroRNA (miRNA) are known to bind to specific target mRNA to regulate post-transcriptional gene expression and are, therefor...

    Authors: Lei Wang, Yan Liu, Zhengtao Yu, Jianwu Gong, Zhiyong Deng, Nianjun Ren, Zhe Zhong, Hao Cai, Zhi Tang, Haofeng Cheng, Shuai Chen and Zhengwen He

    Citation: Journal of Translational Medicine 2021 19:213

    Content type: Research

    Published on:

  29. Optimizing the therapeutic ratio for radiation therapy (RT) in head and neck squamous cell carcinoma (HNSCC) is uniquely challenging owing to high rates of early and late toxicity involving nearby organs at ri...

    Authors: Whitney Sumner, Xenia Ray, Leisa Sutton, Daniel Rebibo, Francesco Marincola, Parag Sanghvi, Vitali Moiseenko and Ida Deichaite

    Citation: Journal of Translational Medicine 2021 19:212

    Content type: Research

    Published on:

  30. Prickle planar cell polarity protein 1 (PRICKLE1), a core component of the non-canonical Wnt/planar cell polarity (PCP) pathway, was recently reported to be upregulated and correlated with poor prognosis in so...

    Authors: Duanfeng Jiang, Yanjuan He, Qiuyu Mo, Enyi Liu, Xin Li, Lihua Huang, Qin Zhang, Fangping Chen, Yan Li and Haigang Shao

    Citation: Journal of Translational Medicine 2021 19:211

    Content type: Research

    Published on:

  31. As a significant cause of malignancy mortality, gastric carcinoma (GC) has been well documented to be an often-fatal diagnosis. Despite the limitations of effective therapy, immunotherapy has emerged as a prom...

    Authors: Qianmei Fu, Xiaohong Tan, Huaming Tang and Jijiang Liu

    Citation: Journal of Translational Medicine 2021 19:210

    Content type: Research

    Published on:

  32. Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive type of renal malignancy. Methyltransferase like 13 (METTL13) functions as an oncogene in most of human cancers, but its function and m...

    Authors: Zhuonan Liu, Tianshui Sun, Chiyuan Piao, Zhe Zhang and Chuize Kong

    Citation: Journal of Translational Medicine 2021 19:209

    Content type: Research

    Published on:

  33. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yini Jiang, Yanqiong Zhang, Weiheng Chen, Chunfang Liu, Xiaomin Li, Danni Sun, Zhenli Liu, Ying Xu, Xia Mao, Qiuyan Guo and Na Lin

    Citation: Journal of Translational Medicine 2021 19:208

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2014 12:334

  34. Inappropriate matching of motor and sensory fibers after nerve repair or nerve grafting can lead to failure of nerve recovery. Identification of motor and sensory fibers is important for the development of new...

    Authors: Xijie Zhou, Jian Du, Liming Qing, Thomas Mee, Xiang Xu, Zhuoran Wang, Cynthia Xu and Xiaofeng Jia

    Citation: Journal of Translational Medicine 2021 19:207

    Content type: Research

    Published on:

  35. Tumor metastasis is the main cause of death of cancer patients, and cancer stem cells (CSCs) is the basis of tumor metastasis. However, systematic analysis of the stemness of prostate cancer cells is still not...

    Authors: Zao Dai and Ping Liu

    Citation: Journal of Translational Medicine 2021 19:206

    Content type: Research

    Published on:

  36. Currently, no molecular classification is established for bladder cancer based on metabolic characteristics. Therefore, we conducted a comprehensive analysis of bladder cancer metabolism-related genes using mu...

    Authors: Chaozhi Tang, Meng Yu, Jiakang Ma and Yuyan Zhu

    Citation: Journal of Translational Medicine 2021 19:205

    Content type: Research

    Published on:

  37. Soft-tissue sarcomas (STS) are a heterogeneous group of mesenchymal tumors for which response to immunotherapies is not well established. Therefore, it is important to risk-stratify and identify STS patients w...

    Authors: Malte Simon, Sadaf S. Mughal, Peter Horak, Sebastian Uhrig, Jonas Buchloh, Bogac Aybey, Albrecht Stenzinger, Hanno Glimm, Stefan Fröhling, Benedikt Brors and Charles D. Imbusch

    Citation: Journal of Translational Medicine 2021 19:204

    Content type: Research

    Published on:

  38. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yuchen Du, Qiuying Chen, Ying Fan, Jianfeng Zhu, Jiangnan He, Haidong Zou, Dazhen Sun, Bowen Xin, David Feng, Michael Fulham, Xiuying Wang, Lisheng Wang and Xun Xu

    Citation: Journal of Translational Medicine 2021 19:203

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2021 19:167

  39. The gut-brain-microbiota axis (GBMAx) coordinates bidirectional communication between the gut and brain, and is increasingly recognized as playing a central role in physiology and disease. MicroRNAs are import...

    Authors: Liang Zhao, Yingze Ye, Lijuan Gu, Zhihong Jian, Creed M. Stary and Xiaoxing Xiong

    Citation: Journal of Translational Medicine 2021 19:202

    Content type: Review

    Published on:

  40. Due to mTOR (mammalian/mechanistic target of rapamycin) gene-loss mice die during embryonic development, the role of mTOR in platelets has not been evaluated using gene knockout technology.

    Authors: Longsheng Wang, Gang Liu, Nannan Wu, Baiyun Dai, Shuang Han, Qiaoyun Liu, Fang Huang, Zhihua Chen, Weihong Xu, Dajing Xia and Cunji Gao

    Citation: Journal of Translational Medicine 2021 19:201

    Content type: Research

    Published on:

  41. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Xiangying Kong, Wenbin Wu, Yue Yang, Hongye Wan, Xiaomin Li, Michun Zhong, Hongyan Zhao, Xiaohui Su, Shiwei Jia, Dahong Ju and Na Lin

    Citation: Journal of Translational Medicine 2021 19:199

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2015 13:91

  42. The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is 30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a global issue with raising ...

    Authors: Wendi Wang, Wei Lei, Lina Jiang, Siqi Gao, Shijun Hu, Zi-Gang Zhao, Chun-Yu Niu and Zhen-Ao Zhao

    Citation: Journal of Translational Medicine 2021 19:198

    Content type: Review

    Published on:

  43. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Neil H. Riordan, Isabela Morales, Giselle Fernández, Nicole Allen, Neal E. Fearnot, Michael E. Leckrone, Dedra Jones Markovich, Darla Mansfield, Dorita Avila, Amit N. Patel, Santosh Kesari and Jorge Paz Rodriguez

    Citation: Journal of Translational Medicine 2021 19:197

    Content type: Correction

    Published on:

    The original article was published in Journal of Translational Medicine 2018 16:57

  44. Scleroderma is an autoimmune disease that causes dermal fibrosis. It occurs when collagen accumulates in tissue as a result of persistent inflammation. Th17 cells and pro-inflammatory cytokines such as IL-1β,...

    Authors: Jeonghyeon Moon, Seon-yeong Lee, Jeong Won Choi, A Ram Lee, Jin Hee Yoo, Su-Jin Moon, Sung-Hwan Park and Mi-La Cho

    Citation: Journal of Translational Medicine 2021 19:192

    Content type: Research

    Published on:

    The Correction to this article has been published in Journal of Translational Medicine 2021 19:266

  45. The timeliness of diagnostic testing after positive screening remains suboptimal because of limited evidence and methodology, leading to delayed diagnosis of lung cancer and over-examination. We propose a radi...

    Authors: Zixing Wang, Ning Li, Fuling Zheng, Xin Sui, Wei Han, Fang Xue, Xiaoli Xu, Cuihong Yang, Yaoda Hu, Lei Wang, Wei Song and Jingmei Jiang

    Citation: Journal of Translational Medicine 2021 19:191

    Content type: Research

    Published on:

Annual Journal Metrics