Fig. 2From: Matrine alleviates depressive-like behaviors via modulating microbiota–gut–brain axis in CUMS-induced miceThe diversity and composition of gut microbiota in different groups. A Principal coordinate analysis (PCoA) plot of beta diversity in different groups by Bray-Curtis distance. Percentages of variance explained by first two axes explain were provided, accounting for 18.2% and 8.8%, respectively. B Unweighted pair group-method with arithmetic means (UPGMA) based on Bray-Curtis dissimilarity matrices. Groups with different letters are significantly different according to PERMANOVA (padj < 0.05). C Taxonomic tree in packed circles. The circles represent phylum, class, order, family, and genus from outside to inside. The abundance of each ASV in the different treatment groups is displayed as a pie chart. D Relative abundances of the top ten ASVs at the phylum level. E Relative abundances of the top ten ASVs at the genus level. F Cladogram showed ASVs with LDA scores greater than 2 based on linear discriminant analysis effect size analysisBack to article page