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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathway

Fig. 4

ADAM12 enhanced the EGFR/ERK signaling pathway in ccRCC. A Volcano plots of the distribution of DEGs by comparing shNC with shADAM12 cell samples and Vector with OE-ADAM12 cell samples. B The distribution of DEGs was plotted on the heatmap. C, D The biological functions of the integrated DEGs were explored by GO and KEGG enrichment analysis. E, F Western blot revealed the expression of EGFR/ERK and c-Myc proteins upon the knockdown and overexpression of ADAM12

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Journal of Translational Medicine

ISSN: 1479-5876

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