Fig. 2

ADAM12 promoted the proliferation of ccRCC cells. A, B ADAM12 was significantly downregulated in CAKI-2 and 786-O cells at both the transcriptional and translational levels after infection with shADAM12 lentivirus. C, D ADAM12 was markedly overexpressed in ACHN and 786-O cells at both the transcriptional and translational levels after infection with OE-ADAM12 lentivirus. E–F CCK-8 assays showed the proliferation capacity of ccRCC cells infected with the indicated lentivirus. G, H Colony formation assay revealed the colony number of ccRCC cells infected with the indicated lentivirus