Skip to main content
  • Retraction Note
  • Open access
  • Published:

Retraction Note: Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability

The Original Article was published on 22 May 2008

Retraction: Journal of Translational Medicine 2008, 6:27 https://doi.org/10.1186/1479-5876-6-27


The Editor-in-Chief has retracted this article [1]. After publication, concerns were raised regarding potential issues in the western blot images presented in the figures. Specifically:

  • Two pairs of bands appear highly similar in Fig. 5a—MSTO C CycD1 (CTRL 3 h and 6 h) and P + C Actin (CTRL 6 h and 24 h).

  • A number of bands appear highly similar in Fig. 6b P + C Actin.

  • Also in Fig. 6b, NCI P p21 bands (CTRL 6 h and 24 h) appear highly similar to P + C p21 bands (CTRL 3 h and 6 h).

  • All NCI Actin bands appear to be highly similar in Figs. 5a and 6b.

  • NCI C Actin bands in Figs. 5a and 6b appear to be highly similar but rotated 180 degrees, with the same bands representing different groups.

  • In Fig. 6b NCI blots, some backgrounds appear inconsistent and contain unexpected breaks or changes between bands.

As the article was published in 2008, the authors are unable to provide the raw data used to produce these figures. The Editor-in-Chief therefore no longer has confidence in the presented data.

Alfonso Baldi does not agree to this retraction. Angela Nebbioso and Lucia Altucci have not explicitly stated whether they agree to this retraction. Simona Menegozzo has not responded to any correspondence from the editor or publisher about this retraction. The Publisher has not been able to obtain a current email address for author Alessandra Verdina, Irene Cardillo, Rossella Galati and Ada Sacchi.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alfonso Baldi.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Verdina, A., Cardillo, I., Nebbioso, A. et al. Retraction Note: Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability. J Transl Med 20, 624 (2022). https://doi.org/10.1186/s12967-022-03834-5

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s12967-022-03834-5