Fig. 6From: C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2ʹ-O-methylation of PARP1Knockdown of FBL or PARP1 reversed the carcinogenic effect of SNORD104. A PARP1 RNA levels in the EC tissues in the TGCA dataset. B Correlation between PARP1 expression and 5-year overall survival (OS) of EC patients from the Kaplan–Meier Plotter (P = 0.037). C FBL and PARP1 were knocked down in SNORD104-overexpressing HEC1B cells. The effect of FBL or PARP1 knockdown on the D, E proliferation, F colony formation, and G apoptosis of SNORD104-overexpressing cells. *P < 0.05Back to article page