Table 4 Summary information for associated genes for the four cancers identified by different tests
Cancer | Gene | chr (pos) | S | r | Burden | KM | IEHC-Fisher | IEHC-adapt | IEHC-optim | IEHC-ACAT |
|---|---|---|---|---|---|---|---|---|---|---|
BRCA | COL9A1 | 6 (70,924,764–71,012,786) | 4,121 |  − 0.32 | 8.94 × 10–2 | 8.43 × 10–1 | 1.41 × 10–1 | 1.54 × 10–1 | 2.18 × 10–1 | 1.56 × 10–1 |
BRCA | MSANTD2 | 11 (124,636,394–124,670,569) | 4,563 |  − 0.16 | 8.94 × 10–2 | 8.43 × 10–1 | 4.64 × 10–1 | 2.03 × 10–1 | 2.20 × 10–1 | 2.33 × 10–1 |
BRCA | LMBRD1 | 6 (70,385,694–70,507,003) | 4,324 | 0.26 | 8.94 × 10–2 | 8.43 × 10–1 | 1.67 × 10–1 | 1.54 × 10–1 | 2.18 × 10–1 | 1.56 × 10–1 |
BRCA | RP11-1391J7.1 | 11 (856,880–859,795) | 4,309 | 0.34 | 1.77 × 10–2 | 8.43 × 10–1 | 1.25 × 10–1 | 3.85 × 10–2 | 5.91 × 10–2 | 4.65 × 10–2 |
COAD | CTA-407F11.6 | 22 (26,043,228–26,045,199) | 4,290 | 0.23 | 9.42 × 10–2 | 8.41 × 10–1 | 6.67 × 10–1 | 2.09 × 10–1 | 3.04 × 10–1 | 2.48 × 10–1 |
OV | KIAA1841 | 2 (61,293,006–61,391,960) | 3,162 | 0.01 | 9.52 × 10–1 | 2.62 × 10–1 | 2.28 × 10–4 | 4.15 × 10–5 | 5.75 × 10–2 | 1.75 × 10–4 |
OV | FAM161A | 2 (62,051,989–62,081,278) | 3,064 | 0.17 | 8.63 × 10–1 | 2.62 × 10–1 | 1.70 × 10–4 | 4.15 × 10–5 | 1.68 × 10–3 | 1.75 × 10–4 |
OV | COMMD1 | 2 (62,115,859–62,374,382) | 3,047 | 0.16 | 9.93 × 10–1 | 2.26 × 10–1 | 6.75 × 10–1 | 5.38 × 10–1 | 1.32 × 10–2 | 4.18 × 10–2 |
STAD | CTC-338M12.5 | 5 (180,618,924–180,621,429) | 1,051 | 0.06 | 9.96 × 10–1 | 5.88 × 10–1 | 6.55 × 10–4 | 9.82 × 10–5 | 4.63 × 10–1 | 4.27 × 10–4 |