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Table 1 Summary information of 10 TCGA cancers and the number of genes, sample sizes and SNPs of these cancers after combining the tissue in GTEx and quality control

From: Integrative eQTL-weighted hierarchical Cox models for SNP-set based time-to-event association studies

Cancer N0 N1 m Age Female/male Censored rate (%) Stage or grade (1/2/3/4/5) Tissue in GTEx N2 k0 k1
ACC 97 75 4,473,001 47.6 ± 16.5 50/25 60.0 8/33/16/18/0 Adrenal gland 175 11,822 11,165
BRCA 1283 736 2,281,892 58.8 ± 13.0 736/0 85.9 138/408/174/11/5 Breast mammary tissue 251 13,068 7,793
COAD 570 201 4,216,239 66.0 ± 13.0 97/104 75.1 34/78/62/27/0 Colon transverse 246 12,779 11,586
LIHC 469 166 3,369,784 62.7 ± 14.1 73/93 60.8 79/44/39/4/0 Liver 153 11,073 8,595
LUAD 877 384 3,831,580 65.9 ± 9.9 213/171 63.0 216/90/62/16/0 Lung 383 13,300 10,617
LUSC 765 344 3,279,532 67.1 ± 8.8 94/250 57.3 176/117/48/3/0 Lung 383 13,300 9,450
OV 758 455 1,527,607 60.2 ± 11.4 455/0 37.4 9/19/353/74/0 Ovary 122 12,623 7,851
PAAD 223 159 4,679,901 65.6 ± 10.8 69/90 45.9 20/130/4/5/0 Pancreas 220 11,173 10,728
STAD 544 249 3,384,736 64.8 ± 10.2 97/152 60.2 33/75/128/13/0 Stomach 237 12,045 9,247
UCEC 605 368 4,008,620 64.4 ± 10.8 368/0 83.2 239/33/79/17/0 Uterus 101 12,592 10,948
  1. N0: the initial sample size in TCGA; N1: the sample size after quality control; m: the number of SNPs after combination; N2: the sample size in GTEx; k0: the number of genes after combination; k1: the number of genes after quality control