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Table 1 Summary information of 10 TCGA cancers and the number of genes, sample sizes and SNPs of these cancers after combining the tissue in GTEx and quality control

From: Integrative eQTL-weighted hierarchical Cox models for SNP-set based time-to-event association studies

Cancer

N0

N1

m

Age

Female/male

Censored rate (%)

Stage or grade (1/2/3/4/5)

Tissue in GTEx

N2

k0

k1

ACC

97

75

4,473,001

47.6 ± 16.5

50/25

60.0

8/33/16/18/0

Adrenal gland

175

11,822

11,165

BRCA

1283

736

2,281,892

58.8 ± 13.0

736/0

85.9

138/408/174/11/5

Breast mammary tissue

251

13,068

7,793

COAD

570

201

4,216,239

66.0 ± 13.0

97/104

75.1

34/78/62/27/0

Colon transverse

246

12,779

11,586

LIHC

469

166

3,369,784

62.7 ± 14.1

73/93

60.8

79/44/39/4/0

Liver

153

11,073

8,595

LUAD

877

384

3,831,580

65.9 ± 9.9

213/171

63.0

216/90/62/16/0

Lung

383

13,300

10,617

LUSC

765

344

3,279,532

67.1 ± 8.8

94/250

57.3

176/117/48/3/0

Lung

383

13,300

9,450

OV

758

455

1,527,607

60.2 ± 11.4

455/0

37.4

9/19/353/74/0

Ovary

122

12,623

7,851

PAAD

223

159

4,679,901

65.6 ± 10.8

69/90

45.9

20/130/4/5/0

Pancreas

220

11,173

10,728

STAD

544

249

3,384,736

64.8 ± 10.2

97/152

60.2

33/75/128/13/0

Stomach

237

12,045

9,247

UCEC

605

368

4,008,620

64.4 ± 10.8

368/0

83.2

239/33/79/17/0

Uterus

101

12,592

10,948

  1. N0: the initial sample size in TCGA; N1: the sample size after quality control; m: the number of SNPs after combination; N2: the sample size in GTEx; k0: the number of genes after combination; k1: the number of genes after quality control