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Table 1 Characteristics of AML patients and experiments

From: Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia

Pt No

Source

% Blasts

Disease status

Molecular mutation

Cytogenetic

Experiments

1

BM

86

New diagnosis

IDH1 + TET2

46,XX

Chi

2

BM

71

New diagnosis

Negative

46,XY

Chi

3

BM

92

Relapse/refractory

FLT3-ITD

Complex

Chi

4

BM

65

New diagnosis

Negative

t(8;21)

Chi

5

BM

46

New diagnosis

Kit D816

t(8;21)

Chi

6

BM

77

Relapse

Negative

Complex

Chi + ADM

7

BM

63

New diagnosis

NPM1 + DNMT3a

46,XY

Chi + ADM

8

BM

90

New diagnosis

FLT3-ITD + NPM1

Complex

Chi + ADM

9

BM

74

New diagnosis

Negative

Inv(16)

Chi + ADM

10

BM

59

Relapse/refractory

FLT3-ITD + DNMT3a

46,XY

Chi + ADM

11

BM

81

Relapse

Negative

47,XX, + 8

Chi + ADM

  1. Pt No Patient number, BM Bone marrow, Chi Chidamide, ADM Adriamycin