Fig. 6

Predicted heteroclitic Trp2 peptide conformation. a The conformation of the heteroclitic Trp2 peptides, bound to the H2-Db molecule, is shown compared to the wt sequence. Contact pattern to the H2-Db are indicated in maroon for both front and rear sides. b Prediction of the heteroclitic peptides’ structure presented to the CD8⁺ T cell for interaction with the TCR