Fig. 5

a Plasma concentrations of MIV-711 in dogs on Day 1, Day 7 and Day 28 and b synovial concentrations of MIV-711 at pre-surgery (24 h after the first dose of MIV-711) and on Day 29 (24 h after last dose of MIV-711). Mean ± SEM. Numbers above columns indicate number of animals sampled. ***p<0.001 vs. right knee