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Table 7 Distribution of autoantibodies by cytokine clusters

From: Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Autoantibody

Neutral (n = 24)

Chemotactic (n = 13)

G-CSF (n = 20)

IFNα/Pro-inflammatory (n = 10)

p-value

RF

8 (33)

3 (23)

8 (40)

5 (50)

0.570

CCP3

1 (4)

0 (0)

0 (0)

0 (0)

0.610

TPOAb

2 (8)

1 (8)

4 (20)

0 (0)

0.342

TgAb

1 (4)

1 (8)

2 (10)

1 (10)

0.882

dsDNA

7 (29)

7 (54)

11 (55)

7 (70)

0.115

ACA-IgM

6 (25)

1 (8)

1 (5)

3 (30)

0.154

ACA-IgG

4 (17)

4 (31)

2 (10)

2 (20)

0.499

β2GP1-IgM

2 (8)

4 (31)

0 (0)

1 (10)

0.042

β2GP1-IgG

1 (4)

2 (15)

1 (5)

2 (20)

0.359

ANAs

18 (75)

12 (92)

19 (95)

8 (80)

0.239

RNP

4 (17)

7 (54)

10 (50)

4 (40)

0.062

Ro

9 (37)

4 (31)

7 (35)

6 (60)

0.496

La

1 (4)

1 (8)

2 (10)

1 (10)

0.882

Sm

1 (4)

3 (23)

5 (25)

3 (30)

0.172

  1. Data correspond to number of patients (%)
  2. RF rheumatoid factor, CCP3 anti-cyclic citrullinated peptide third-generation, TPOAb anti-thyroperoxidase antibody, TgAb anti-thyroglobulin antibody, dsDNA anti-double stranded DNA antibodies, ACA anticardiolipin antibody, β2GP1 β2 glycoprotein-1, ANAs antinuclear antibodies