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Table 7 Distribution of autoantibodies by cytokine clusters

From: Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Autoantibody Neutral (n = 24) Chemotactic (n = 13) G-CSF (n = 20) IFNα/Pro-inflammatory (n = 10) p-value
RF 8 (33) 3 (23) 8 (40) 5 (50) 0.570
CCP3 1 (4) 0 (0) 0 (0) 0 (0) 0.610
TPOAb 2 (8) 1 (8) 4 (20) 0 (0) 0.342
TgAb 1 (4) 1 (8) 2 (10) 1 (10) 0.882
dsDNA 7 (29) 7 (54) 11 (55) 7 (70) 0.115
ACA-IgM 6 (25) 1 (8) 1 (5) 3 (30) 0.154
ACA-IgG 4 (17) 4 (31) 2 (10) 2 (20) 0.499
β2GP1-IgM 2 (8) 4 (31) 0 (0) 1 (10) 0.042
β2GP1-IgG 1 (4) 2 (15) 1 (5) 2 (20) 0.359
ANAs 18 (75) 12 (92) 19 (95) 8 (80) 0.239
RNP 4 (17) 7 (54) 10 (50) 4 (40) 0.062
Ro 9 (37) 4 (31) 7 (35) 6 (60) 0.496
La 1 (4) 1 (8) 2 (10) 1 (10) 0.882
Sm 1 (4) 3 (23) 5 (25) 3 (30) 0.172
  1. Data correspond to number of patients (%)
  2. RF rheumatoid factor, CCP3 anti-cyclic citrullinated peptide third-generation, TPOAb anti-thyroperoxidase antibody, TgAb anti-thyroglobulin antibody, dsDNA anti-double stranded DNA antibodies, ACA anticardiolipin antibody, β2GP1 β2 glycoprotein-1, ANAs antinuclear antibodies