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Table 1 Clinical characteristics of patients with coronary artery disease and diabetes mellitus type 2

From: Disturbed angiogenic activity of adipose-derived stromal cells obtained from patients with coronary artery disease and diabetes mellitus type 2

Clinical characteristics

Groups of patients

p

Control

CAD

CAD + DM2

Number of patients

19

32

28

-

Age, years

56,7 ± 12,3

62,3 ± 8,6

61,0 ± 8,2

NS

Gender, male, n (%)

5 (26,3%)

29 (90,6%)

17 (60,7%)

<0,05

Functional class of stable angina, n (%)

-

II FC-8 (25%),

II FC-5 (18%),

NS

III FC - 13 (41%),

III FC-9 (32%),

IV FC – 11 (34%)

IV FC-14 (50%)

MI in past history, n (%)

-

20 (63%)

18 (64%)

NS

The score of coronary artery atherosclerosis, n (%)

-

2CA-6 (18,8%)

2CA-5 (17,9%)

NS

3CA-26 (81,3%)

3CA-23 (82,1%)

Ejection fraction (%)

57,8 ± 1,8

55,0 ± 9,8

58,0 ± 9,2

NS

Arterial hypertension, n (%)

3 (15,8%)

27 (84%)

24 (86%)

<0,05

Obesity, n (%)

12 (63%)

20 (63%)

19 (68%)

NS

BMI, kg/m2

28,6 ± 3,7

30,6 ± 0,8

28,14 ± 1,07

NS

Total protein, g/l

68,7 ± 1,9

69,4 ± 1,6

72,1 ± 3,2

NS

Glucose, mmol/l

5,46 ± 2,2

5,4 ± 3,2

10,1 ± 4,1

<0,05

Triglyceride, mmol/l

1,7 ± 1,3

2,1 ± 1,1

1,9 ± 0,9

NS

Cholesterol, mmol/l

4,4 ± 0,4

4,5 ± 0,4

4,9 ± 0,9

NS

Urea, mmol/l

5,9 ± 0,8

6,2 ± 0,5

9,02 ± 1,5

NS

Creatinine, ummol/l

68,8 ± 9,5

66,6 ± 7,5

139,8 ± 23,2

<0,01

Medical treatment before CABG

β-blockers, n (%)

-

27 (84%)

23 (82%)

NS

Antiplatelet agents, n (%)

-

32 (100%)

28 (100%)

NS

Statins, n (%)

-

28 (88%)

25 (89%)

NS

ACE inhibitors, n (%)

-

20 (63%)

18 (64%)

NS

Calcium antagonists, n (%)

-

13 (41%)

12 (43%)

NS

Diuretics, n (%)

-

23 (72%)

21 (75%)

NS

Nitrates, n (%)

-

27 (84%)

23 (82%)

NS

  1. FC – Functional class, BMI – Body mass index, CABG – Coronary artery bypass grafting, p – p-value for multiple comparison of patient’s groups, NS – Non-significant.