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Table 4 HIV isolate coverage provided by identified epitope regions.

From: Defining epitope coverage requirements for T cell-based HIV vaccines: Theoretical considerations and practical applications

Protein

Epitope

Intra-subtype Coverage

Global Coverage

  

(CRF01_AE)

(All Group M)

Gag

VDRFYKTLRAE

89.7%

42.1%

 

NFPQSRPEPTAPPAE

58.6%

42.4%

 

All Gag

95.7%

66.7%

Env

VHALFYKLDIVPIED

20.70%

6.9%

 

EKLKEHFNNKTIIFQ

0%

0%

 

EISNYTNQIYEILTE

45.10%

2.8%

 

EPDRSERIEEGGGEQ

30.6%

5.7%

 

All Env

69.9%

14.7%

Overall

Gag and Env

98.7%

71.6%