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Table 3 Results of the Cox regression analysis summarizing significant independent prognostic factors in the overall material.

From: The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas

Factor Hazard Ratio 95% CI P
Age    
   ≤60 1.0   
   >60 1.5 1.0-2.1 0.038
Tumor depth    
   Superficial 1.0   
   Deep 11 1.5-79 0.018
Malignancy grade    <0.001*
   1 1.0   
   2 2.4 1.3-4.2 0.003
   3 3.7 2.1-6.6 <0.001
Metastasis at the time of diagnosis    
   No 1.0   
   Yes 1.9 1.2-3.1 0.010
Surgery    
   Yes 1.0   
   No 2.2 1.1-4.4 0.031
Resection-margins    
   Free 1.0   
   Non-free 2.5 1.6-3.8 <0.001
PI3K   
   Negative 1.0   
   Positive 1.5 1.0-2.2 0.042
  1. Abbreviations: PI3K, phosphoinositide-3-kinase.
  2. * Overall significance as a prognostic factor