Table 3 Results of the Cox regression analysis summarizing significant independent prognostic factors in the overall material.
Factor | Hazard Ratio | 95% CI | P |
|---|---|---|---|
Age | Â | Â | Â |
   ≤60 | 1.0 |  |  |
   >60 | 1.5 | 1.0-2.1 | 0.038 |
Tumor depth | Â | Â | Â |
   Superficial | 1.0 |  |  |
   Deep | 11 | 1.5-79 | 0.018 |
Malignancy grade | Â | Â | <0.001* |
   1 | 1.0 |  |  |
   2 | 2.4 | 1.3-4.2 | 0.003 |
   3 | 3.7 | 2.1-6.6 | <0.001 |
Metastasis at the time of diagnosis | Â | Â | Â |
   No | 1.0 |  |  |
   Yes | 1.9 | 1.2-3.1 | 0.010 |
Surgery | Â | Â | Â |
   Yes | 1.0 |  |  |
   No | 2.2 | 1.1-4.4 | 0.031 |
Resection-margins | Â | Â | Â |
   Free | 1.0 |  |  |
   Non-free | 2.5 | 1.6-3.8 | <0.001 |
PI3K | Â | Â | |
   Negative | 1.0 |  |  |
   Positive | 1.5 | 1.0-2.2 | 0.042 |