Table 1 Patient demographic data and status of microRNA methylation
From: Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
sex | age | Diagnosis | Symptoms at diagnosis | myeloid transformation | JAK2 V617F mutation | miR-34b/c | miR-34a | miR-203 | miR-124-1 |
|---|---|---|---|---|---|---|---|---|---|
F | 78 | ET | Epigastric pain | No | yes | U | U | M | U |
F | 81 | ET | Epigastric pain | No | yes | U | U | U | U |
M | 32 | ET | erythromelalgia | No | yes | U | U | U | U |
M | 81 | ET | N/A | No | yes | U | U | U | U |
M | 59 | ET | N/A | N/A (No record) | yes | M | U | U | U |
M | 76 | ET | Nil | No | yes | U | M | U | U |
M | 53 | ET | Nil | MDS | yes | U | U | U | U |
F | 89 | ET | Nil | N/A (No record) | yes | U | U | U | U |
F | 43 | ET | Nil | N/A (No record) | yes | M | U | M | U |
F | 82 | ET | Nil | No | yes | U | U | U | U |
M | 78 | ET | Nil | No | yes | U | U | U | U |
F | 79 | ET | Nil | No | yes | U | U | U | U |
M | 84 | ET | Nil | AML | yes | U | U | U | U |
F | 74 | ET | Nil | No | yes | M | U | M | U |
F | 56 | ET | Nil | No | yes | U | U | U | U |
M | 60 | ET | Nil | No | N/A | U | U | U | U |
M | 68 | ET | Nil | AML | yes | U | U | U | U |
M | 39 | ET | Nil | No | yes | U | U | U | U |
F | 79 | ET | Weight loss | No | yes | U | U | U | U |
F | 60 | ET | erythromelalgia | No | no | U | U | U | U |
M | 63 | ET | Minor stroke (LUL numbness) | No | no | U | U | U | U |
M | 47 | ET | erythromelalgia | No | no | U | U | U | U |
F | 62 | ET | erythromelalgia, Headache | No | no | U | U | U | U |
F | 83 | ET | N/A | N/A (No record) | no | U | U | M | U |
F | 32 | ET | Nil | N/A (No record) | no | U | U | U | U |
F | 42 | ET | Nil | No | no | M | U | U | U |
M | 85 | ET | Nil | No | no | U | U | U | U |
M | 71 | ET | Nil | No | no | U | U | U | U |
F | 28 | ET | Nil | No | no | U | U | U | U |
F | 87 | ET | Nil | No | no | U | U | U | U |
M | 48 | ET | Nil | No | no | U | U | U | U |
M | 48 | ET | Nil | No | no | U | U | U | U |
M | 41 | ET | epistaxis | No | N/A | U | U | U | U |
M | 82 | ET | N/A | No | N/A | U | U | U | U |
F | 41 | PMF | Easy bruising | N/A (No record) | yes | U | U | U | U |
M | 67 | PMF | Nil | No | yes | U | U | U | U |
F | 82 | PMF | Nil | No | yes | U | U | U | U |
F | 42 | PV | Minor stroke (RUL paraesthesia) | No | yes | U | U | U | U |
M | 48 | PV | Gum bleeding | No | yes | U | U | U | U |
F | 75 | PV | Nil | AML | yes | U | U | U | U |
M | 78 | PV | Nil | No | yes | U | U | U | U |
M | 57 | PV | Visual blurring (BRAO) | No | yes | U | U | U | U |
M | 44 | PV | abdominal pain (splenic infarction) | No | no | U | U | U | U |
M | 71 | PV | Gum bleeding | MDS | N/A | U | U | U | U |
F | 77 | PV | N/A | No | N/A | U | U | U | U |