HLA class I and II genotype of the NCI-60 cell lines

Adams, Sharon; Robbins, Fu-Meei; Chen, Deborah; Wagage, Devika; Holbeck, Susan L; Morse, Herbert C; Stroncek, David; Marincola, Francesco M

doi:10.1186/1479-5876-3-11

Journal of Translational Medicine

Table 2 Sequence-based typing of NCI-60 HLA class I Loci

From: HLA class I and II genotype of the NCI-60 cell lines

Cell Line	ID	Tissue	A locus	B Locus	Cw Locus
BT-549	41292-D	Breast CA	N.R.	151701, 5501	030301, 07^a
HS 578T	41293-D	Breast CA	03^a, 24^a	35^a, 40^a	030401, 04^a
MCF7	41294-D	Breast CA	020101	18^a, 44^a	05^a
MDA-MB-231	41296-D	Breast CA	0201, 0217	4002, 4101	020202, 17^a
MDA-MB435	41297-D	Breast CA	110101, 240201	15^a, 35^a	030301, 04^a
T47D	41298-D	Breast CA	3301	1402	0802
SF-268	41286-D	CNS CA	010101, 3201	0801, 4002	020202, 07^a
SF-295	41287-D	CNS CA	010101, 2601	070201, 5501	03^a, 07^a
SF-539	41288-D	CNS CA	020101	08^a, 35^a	04^a, 07^a
SNB-19	41289-D	CNS CA	020101	18^a	05^a
SNB-75	41290-D	CNS CA	020101, 110101	35^a, 39^a	04^a, 120301
U251	41291-D	CNS CA	020101	18^a	05^a
COLO 205	41299-D	Colon CA	01^a, 02^a	07^a, 08^a	070201, 07^a
HCC-2998	41300-D	Colon CA	02^a, 24^a	3701, 400601	04^a, 0602
HCT-116	41301-D	Colon CA	01^a, 02^a	18^a, 4501	05^a, 07^a
HCT-15	41302-D	Colon CA	02^a, 24^a	08new, 350101	04^a, 07^a
HT29	41303-D	Colon CA	01^a, 24^a	35^a, 440301	04^a
KM12	41304-D	Colon CA	02new	70201	70201
SW-620	41305-D	Colon CA	02^a, 24^a	07^a, 15^a	070201, 07^a
MOLT 4	41281-D	Leukemia, ALL	010101, 2501	18^a, 570101	0602, 120301
CCRF-CEM	41282-D	Leukemia, ALL	N.R.	08^a, 40^a	030401, 07^a
HL-60	41284-D	Leukemia, APL	10101	570101	0602
K-562	41280-D	Leukemia, CML	110101, 310102	18^a, 40^a	03^a, N.R.
SR	41285-D	Leukemia, LCIL	02^a, 03^a	3701, 3901	0602, 120301
LOX IMVI	41315-D	Melanoma	110101, 2902	070201, 440301	070201, 1601
M 14	41316-D	Melanoma	110101, 240201	15^a, 35^a	030301, 04^a
SK-MEL-2	41317-D	Melanoma	03^a, 26^a	35^a, 38^a	04^a, 120301
SK-MEL-5	41319-D	Melanoma	020101, 110101	07^a, 40^a	030401, 070201
SK-MEL-28	41318-D	Melanoma	110101	4001	030401
UACC-62	41321-D	Melanoma	02^a, 32^a	39^a, 44^a	05^a, 12^a
UACC-257	41320-D	Melanoma	020101	18^a, 44^a	05^a, 07^a
RPMI-8226	41283-D	MM	3001, 6802	1503, 1510	020204, 030402
A549/ATCC	41306-D	NSCLC	2501, 3001	18^a, 440301	120301, 1601
EKVX	41307-D	NSCLC	010101	3701	0602
HOP-62	41308-D	NSCLC	030101	07^a, 44^a	05^a, 070201
HOP-92	41309-D	NSCLC	03^a, 24^a	27^a, 470101	01^a, 06^a
NCI-H23	41312-D	NSCLC	8001	5001	0602
NCI-H226	41311-D	NSCLC	010101, 240201	07^a, 39^a	070201, 120301
NCI-H322M	41310-D	NSCLC	2902	440301	1601
NCI-H460	41313-D	NSCLC	24^a, 68^a	35^a, 51^a	03^a, 15^a
NCI-H522	41314-D	NSCLC	020101	44^a, 5501	030301, 05^a
IGROV1	41322-D	Ovarian CA	240201, 3301	4901	07^a
OVCAR-3	41323-D	Ovarian CA	020101, 2902	070201, 5801	070201, 07^a
OVCAR-4	41324-D	Ovarian CA	010101, 3201	0801, 4002	07^a, 15^a
OVCAR-5	41325-D	Ovarian CA	01^a, 02^a	08^a, 44^a	05^a, 07^a
OVCAR-8	41326-D	Ovarian CA	010101, 2501	570101	0602
NCI/ADR-RES	41295-D	Ovarian CA	010101, 2501	570101	0602
SK-OV-3	41327-D	Ovarian CA	03^a, 68^a	18^a, 35^a	04^a, 05^a
DU-145	41328-D	Prostate CA	030101, 3303	5001, 570101	0602
PC-3	41329-D	Prostate CA	010101, 240201	1302, 5501	01^a, 06^a
786-O	41330-D	Renal CA	030101	07^a, 44^a	05^a, 070201
A498	41331-D	Renal CA	020101	0801	07^a
ACHN	41332-D	Renal CA	2601	4901	07^a
CAKI-1	41333-D	Renal CA	2301, 240201	3502, 440301	04^a, 04new
SN12C	41334-D	Renal CA	03, 24new	07^a, 44^a	05^a, 070201
TK-10	41335-D	Renal CA	3301	1402	0802
UO-31	41336-D	Renal CA	010101, 030101	07^a, 14^a	07^a, 08^a
RXF-393	41337-D	Renal CA	02^a, 24^a	1401, 44^a	05^a, 0802

Sequence-based typing for the HLA class I loci are reported with the highest degree of resolution. Non-resolved ambiguities are reported as two digit denominations with a superscript ^a as previously described 43. HLA typings divergent from those originally described in the ATCC database are reported in red. ID# refers to the HLA laboratory reference number. New alleles are indicated by the suffix new following the allele. N.R. – Ambiguity not resolved at the lower level of resolution.

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ISSN: 1479-5876

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