Skip to main content

Advertisement

Table 2 Sequence-based typing of NCI-60 HLA class I Loci

From: HLA class I and II genotype of the NCI-60 cell lines

Cell Line ID Tissue A locus B Locus Cw Locus
BT-549 41292-D Breast CA N.R. 151701, 5501 030301, 07a
HS 578T 41293-D Breast CA 03a, 24a 35a, 40a 030401, 04a
MCF7 41294-D Breast CA 020101 18a, 44a 05a
MDA-MB-231 41296-D Breast CA 0201, 0217 4002, 4101 020202, 17a
MDA-MB435 41297-D Breast CA 110101, 240201 15a, 35a 030301, 04a
T47D 41298-D Breast CA 3301 1402 0802
SF-268 41286-D CNS CA 010101, 3201 0801, 4002 020202, 07a
SF-295 41287-D CNS CA 010101, 2601 070201, 5501 03a, 07a
SF-539 41288-D CNS CA 020101 08a, 35a 04a, 07a
SNB-19 41289-D CNS CA 020101 18a 05a
SNB-75 41290-D CNS CA 020101, 110101 35a, 39a 04a, 120301
U251 41291-D CNS CA 020101 18a 05a
COLO 205 41299-D Colon CA 01a, 02a 07a, 08a 070201, 07a
HCC-2998 41300-D Colon CA 02a, 24a 3701, 400601 04a, 0602
HCT-116 41301-D Colon CA 01a, 02a 18a, 4501 05a, 07a
HCT-15 41302-D Colon CA 02a, 24a 08new, 350101 04a, 07a
HT29 41303-D Colon CA 01a, 24a 35a, 440301 04a
KM12 41304-D Colon CA 02new 70201 70201
SW-620 41305-D Colon CA 02a, 24a 07a, 15a 070201, 07a
MOLT 4 41281-D Leukemia, ALL 010101, 2501 18a, 570101 0602, 120301
CCRF-CEM 41282-D Leukemia, ALL N.R. 08a, 40a 030401, 07a
HL-60 41284-D Leukemia, APL 10101 570101 0602
K-562 41280-D Leukemia, CML 110101, 310102 18a, 40a 03a, N.R.
SR 41285-D Leukemia, LCIL 02a, 03a 3701, 3901 0602, 120301
LOX IMVI 41315-D Melanoma 110101, 2902 070201, 440301 070201, 1601
M 14 41316-D Melanoma 110101, 240201 15a, 35a 030301, 04a
SK-MEL-2 41317-D Melanoma 03a, 26a 35a, 38a 04a, 120301
SK-MEL-5 41319-D Melanoma 020101, 110101 07a, 40a 030401, 070201
SK-MEL-28 41318-D Melanoma 110101 4001 030401
UACC-62 41321-D Melanoma 02a, 32a 39a, 44a 05a, 12a
UACC-257 41320-D Melanoma 020101 18a, 44a 05a, 07a
RPMI-8226 41283-D MM 3001, 6802 1503, 1510 020204, 030402
A549/ATCC 41306-D NSCLC 2501, 3001 18a, 440301 120301, 1601
EKVX 41307-D NSCLC 010101 3701 0602
HOP-62 41308-D NSCLC 030101 07a, 44a 05a, 070201
HOP-92 41309-D NSCLC 03a, 24a 27a, 470101 01a, 06a
NCI-H23 41312-D NSCLC 8001 5001 0602
NCI-H226 41311-D NSCLC 010101, 240201 07a, 39a 070201, 120301
NCI-H322M 41310-D NSCLC 2902 440301 1601
NCI-H460 41313-D NSCLC 24a, 68a 35a, 51a 03a, 15a
NCI-H522 41314-D NSCLC 020101 44a, 5501 030301, 05a
IGROV1 41322-D Ovarian CA 240201, 3301 4901 07a
OVCAR-3 41323-D Ovarian CA 020101, 2902 070201, 5801 070201, 07a
OVCAR-4 41324-D Ovarian CA 010101, 3201 0801, 4002 07a, 15a
OVCAR-5 41325-D Ovarian CA 01a, 02a 08a, 44a 05a, 07a
OVCAR-8 41326-D Ovarian CA 010101, 2501 570101 0602
NCI/ADR-RES 41295-D Ovarian CA 010101, 2501 570101 0602
SK-OV-3 41327-D Ovarian CA 03a, 68a 18a, 35a 04a, 05a
DU-145 41328-D Prostate CA 030101, 3303 5001, 570101 0602
PC-3 41329-D Prostate CA 010101, 240201 1302, 5501 01a, 06a
786-O 41330-D Renal CA 030101 07a, 44a 05a, 070201
A498 41331-D Renal CA 020101 0801 07a
ACHN 41332-D Renal CA 2601 4901 07a
CAKI-1 41333-D Renal CA 2301, 240201 3502, 440301 04a, 04new
SN12C 41334-D Renal CA 03, 24new 07a, 44a 05a, 070201
TK-10 41335-D Renal CA 3301 1402 0802
UO-31 41336-D Renal CA 010101, 030101 07a, 14a 07a, 08a
RXF-393 41337-D Renal CA 02a, 24a 1401, 44a 05a, 0802
  1. Sequence-based typing for the HLA class I loci are reported with the highest degree of resolution. Non-resolved ambiguities are reported as two digit denominations with a superscript a as previously described 43. HLA typings divergent from those originally described in the ATCC database are reported in red. ID# refers to the HLA laboratory reference number. New alleles are indicated by the suffix new following the allele. N.R. – Ambiguity not resolved at the lower level of resolution.