Figure 7

Changes in protein expressions of tumor necrotic factor (TNF)-α, nuclear factor (NF)-κB and intercellular adhesion molecule (ICAM)-1 in kidney at 24 h and 72 h after ischemia-reperfusion (IR) procedure (n = 6 at each time for each group). A and B) The analytical results of TNF-α protein expression in kidney parenchyma at 24 h (A) and 72 h (B) after IR procedure. * vs. other groups with different symbols (*, †, ‡), p < 0.01 at 24 h and 72 h, respectively. C and D) The analytical results of NF-κB protein expression in kidney parenchyma at 24 h (C) and 72 h (D) after IR procedure. * vs. other groups with different symbols (*, †, ‡), p < 0.001 at 24 h and 72 h, respectively. E and F) The analytical results of ICAM-1 protein expression in kidney parenchyma at 24 h (E) and 72 h (F) after IR procedure. * vs. other groups with different symbols (*, †, ‡), p < 0.01 at 24 h and 72 h, respectively. All statistical analyses were with one-way ANOVA followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡) indicate significance at the 0.05 level. SC = sham control; IR = ischemia-reperfusion; Sita = sitagliptin; Ex-4 = extendin-4.